Mmu-miR-702 functions as an anti-apoptotic mirtron by mediating ATF6 inhibition in mice

Gene

Volumn 531, Issue 2, 2013, Pages 235-242

  Zhang, Wei guang ^a   Chen, Lin ^b   Dong, Qin ^a   He, Juan ^a   Zhao, Han dong ^a   Li, Feng lan ^a   Li, Hui ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b Harbin Red Cross Central Hospital   (China)

Author keywords

Apoptosis; Isoproterenol; MicroRNA; MiR 702; Short hairpin introns

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CASPASE 3; ISOPRENALINE; LUCIFERASE; MICRORNA; MOUSE MICRORNA 702; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BINDING SITE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; GENE OVEREXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN GENOME; IN VITRO STUDY; IN VIVO STUDY; INTRON; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; WESTERN BLOTTING;

78KDA GLUCOSE-REGULATED PROTEIN; ACTIVATING TRANSCRIPTION FACTOR 6; APOPTOSIS; ATF6; B-CELL CLL/LYMPHOMA 2; BAX; BCL2; BCL2-ASSOCIATED X PROTEIN; C/EBP HOMOLOGOUS PROTEIN; CHOP; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS RESPONSE ELEMENT; ER; ERSE; GRP78; ISO; ISOPROTERENOL; MICRORNA; MIR-702; MMU-MIR-702; MOUSE MICRORNA-702; SHORT HAIRPIN INTRONS; UNFOLDED PROTEIN RESPONSE; UNTRANSLATED REGIONS; UPR; UTR; X-BOX BINDING PROTEIN 1; XBP1;

ACTIVATING TRANSCRIPTION FACTOR 6; ANIMALS; APOPTOSIS; DOWN-REGULATION; HEK293 CELLS; HUMANS; ISOPROTERENOL; MALE; MICE; MICE, INBRED C57BL; MICRORNAS; MYOCARDIUM; MYOCYTES, CARDIAC; NIH 3T3 CELLS;

MUS;

EID: 84885418155     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2013.09.005     Document Type: Article

References (37)

1. Adachi Y., Yamamoto K., Okada T., Yoshida H., Harada A., Mori K. ATF6 is a transcription factor specializing in the regulation of quality control proteins in the endoplasmic reticulum. Cell Struct. Funct. 2008, 33:75-89.
2. Ambros V. MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing. Cell 2003, 113:673-676.
3. Belmont P.J., Chen W.J., Thuerauf D.J., Glembotski C.C. Regulation of microRNA expression in the heart by the ATF6 branch of the ER stress response. J. Mol. Cell. Cardiol. 2012, 52:1176-1182.
4. Friedman R.C., Farh K.K., Burge C.B., Bartel D.P. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res. 2009, 19:92-105.
5. Galindo I., Hernaez B., Munoz-Moreno R., Cuesta-Geijo M.A., Dalmau-Mena I., Alonso C. The ATF6 branch of unfolded protein response and apoptosis are activated to promote African swine fever virus infection. Cell Death Dis. 2012, 3:e341.
6. Glazov E.A., Cottee P.A., Barris W.C., Moore R.J., Dalrymple B.P., Tizard M.L. A microRNA catalog of the developing chicken embryo identified by a deep sequencing approach. Genome Res. 2008, 18:957-964.
7. Haze K., Yoshida H., Yanagi H., Yura T., Mori K. Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress. Mol. Biol. Cell. 1999, 10:3787-99.
8. Hsu P.L., Su B.C., Kuok Q.Y., Mo F.E. Extracellular matrix protein CCN1 regulates cardiomyocyte apoptosis in mice with stress-induced cardiac injury. Cardiovasc. Res. 2013, 98:64-72.
9. Hudecova S., Lencesova L., Csaderova L., Sedlak J., Bohacova V., Laukova M., Krizanova O. Isoproterenol accelerates apoptosis through the over-expression of the sodium/calcium exchanger in HeLa cells. Gen. Physiol. Biophys. 2013, 32:311-23.
10. Iwai-Kanai E., Hasegawa K., Araki M., Kakita T., Morimoto T., Sasayama S. Alpha- and beta-adrenergic pathways differentially regulate cell type-specific apoptosis in rat cardiac myocytes. Circulation 1999, 100:305-311.
11. Jin Y.T., et al. Magnesium attenuates isoproterenol-induced acute cardiac dysfunction and beta-adrenergic desensitization. Am. J. Physiol. Heart Circ. Physiol. 2007, 292:H1593-H1599.
12. Kim B.M., Choi M.Y. Non-canonical microRNAs miR-320 and miR-702 promote proliferation in Dgcr8-deficient embryonic stem cells. Biochem. Biophys. Res. Commun. 2012, 426:183-189.
13. Kurata M., et al. Anti-apoptotic function of Xbp1 as an IL-3 signaling molecule in hematopoietic cells. Cell Death Dis. 2011, 2:e118.
14. Lai E., Teodoro T., Volchuk A. Endoplasmic reticulum stress: signaling the unfolded protein response. Physiology (Bethesda) 2007, 22:193-201.
15. Lee R.C., Ambros V. An extensive class of small RNAs in Caenorhabditis elegans. Science 2001, 294:862-864.
16. Li P. MicroRNAs in cardiac apoptosis. J. Cardiovasc. Transl. Res. 2010, 3:219-224.
17. Liao X., Che X., Zhao W., Zhang D., Bi T., Wang G. The beta-adrenoceptor antagonist, propranolol, induces human gastric cancer cell apoptosis and cell cycle arrest via inhibiting nuclear factor kappaB signaling. Oncol. Rep. 2010, 24:1669-1676.
18. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25:402-408.
19. Logue S.E., Cleary P., Saveljeva S., Samali A. New directions in ER stress-induced cell death. Apoptosis 2013, 18:537-546.
20. Maimaitiyiming H., Li Y., Cui W., Tong X., Norman H., Qi X., Wang S. Increasing cGMP-dependent protein kinase I activity attenuates cisplatin-induced kidney injury through protection of mitochondria function. Am. J. Physiol. Renal Physiol. 2013, 305:F881-90.
21. Mineno J., et al. The expression profile of microRNAs in mouse embryos. Nucleic Acids Res. 2006, 34:1765-1771.
22. Nakanishi K., Sudo T., Morishima N. Endoplasmic reticulum stress signaling transmitted by ATF6 mediates apoptosis during muscle development. J. Cell Biol. 2005, 169:555-560.
23. Okamura K., Hagen J.W., Duan H., Tyler D.M., Lai E.C. The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell 2007, 130:89-100.
24. Okamura K., Chung W.J., Lai E.C. The long and short of inverted repeat genes in animals: microRNAs, mirtrons and hairpin RNAs. Cell Cycle 2008, 7:2840-2845.
25. Oyadomari S., Mori M. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ. 2004, 11:381-389.
26. Quail D.F., et al. Embryonic morphogen nodal promotes breast cancer growth and progression. PLoS One 2012, 7:e48237.
27. Rehmsmeier M., Steffen P., Hochsmann M., Giegerich R. Fast and effective prediction of microRNA/target duplexes. RNA 2004, 10:1507-1517.
28. Ruby J.G., Jan C.H., Bartel D.P. Intronic microRNA precursors that bypass Drosha processing. Nature 2007, 448:83-86.
29. Singh K., Communal C., Sawyer D.B., Colucci W.S. Adrenergic regulation of myocardial apoptosis. Cardiovasc. Res. 2000, 45:713-719.
30. Teixeira M., et al. Cardiac antiapoptotic and proproliferative effect of recombinant human erythropoietin in a moderate stage of chronic renal failure in the rat. J. Pharm. Bioallied Sci. 2012, 4:76-83.
31. Tsukano H., et al. The endoplasmic reticulum stress-C/EBP homologous protein pathway-mediated apoptosis in macrophages contributes to the instability of atherosclerotic plaques. Arterioscler. Thromb. Vasc. Biol. 2010, 30:1925-1932.
32. Vaughan A.T., Betti C.J., Villalobos M.J. Surviving apoptosis. Apoptosis 2002, 7:173-177.
33. Westholm J.O., Lai E.C. Mirtrons: microRNA biogenesis via splicing. Biochimie 2011, 93:1897-1904.
34. Yao S., et al. Activating transcription factor 6 mediates oxidized LDL-induced cholesterol accumulation and apoptosis in macrophages by up-regulating CHOP expression. J. Atheroscler. Thromb. 2013, 20:94-107.
35. Yoshida H., Haze K., Yanagi H., Yura T., Mori K. Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors. J. Biol. Chem. 1998, 273:33741-33749.
36. Yoshida H., Matsui T., Yamamoto A., Okada T., Mori K. XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell 2001, 107:881-891.
37. Zhuo X.Z., et al. Isoproterenol instigates cardiomyocyte apoptosis and heart failure via AMPK inactivation-mediated endoplasmic reticulum stress. Apoptosis 2013, 18:800-810.