Monascuspiloin enhances the radiation sensitivity of human prostate cancer cells by stimulating endoplasmic reticulum stress and inducing autophagy

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Chiu, Hui Wen ^a   Fang, Wen Hung ^a   Chen, Yen Lin ^b   Wu, Ming Der ^b   Yuan, Gwo Fang ^b   Ho, Sheng Yow ^c   Wang, Ying Jan ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b FOOD INDUSTRY RESEARCH AND DEVELOPMENT INSTITUTE   (Taiwan)

^c TAINAN SIN LAU HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

INITIATION FACTOR 2ALPHA; MAMMALIAN TARGET OF RAPAMYCIN; MONASCUSPILOIN; PIGMENT; PROTEIN IRE1; PROTEIN IRE1 ALPHA; PROTEIN KINASE B; RADIOSENSITIZING AGENT; S6 KINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CANCER INHIBITION; CANCER RADIOTHERAPY; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG STRUCTURE; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTERMETHOD COMPARISON; IONIZING RADIATION; MALE; MONASCUS PILOSUS; MOUSE; NONHUMAN; PROSTATE CANCER; PROTEIN EXPRESSION; RADIOSENSITIVITY; SURVIVAL RATE; TUMOR VOLUME; TUMOR XENOGRAFT;

ANIMALS; AUTOPHAGY; BIOLOGICAL AGENTS; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM STRESS; HETEROCYCLIC COMPOUNDS, 3-RING; HUMANS; MALE; MICE; MICE, NUDE; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; RADIATION TOLERANCE; RADIATION-SENSITIZING AGENTS;

MONASCUS PILOSUS; MONASCUS PURPUREUS;

EID: 84863630617     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040462     Document Type: Article

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