-
1
-
-
43049176549
-
Effect of folic acid and B vitamins on risk of cardiovascular events and total mortality among women at high risk for cardiovascular disease: A randomized trial
-
DOI 10.1001/jama.299.17.2027
-
Albert, C.M., Cook, N.R., Gaziano, J.M., Zaharris, E., MacFadyen, J., Danielson, E., Buring, J.E., Manson, J.E., 2008. Effect of folic acid and B vitamins on risk of cardiovascular events and total mortality among women at high risk for cardiovascular disease: a randomized trial. JAMA 299, 2027-2036. (Pubitemid 351656584)
-
(2008)
JAMA - Journal of the American Medical Association
, vol.299
, Issue.17
, pp. 2027-2036
-
-
Albert, C.M.1
Cook, N.R.2
Gaziano, J.M.3
Zaharris, E.4
MacFadyen, J.5
Danielson, E.6
Buring, J.E.7
Manson, J.E.8
-
2
-
-
33748645122
-
5-Methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: Effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling
-
DOI 10.1161/CIRCULATIONAHA.106.612325, PII 0000301720060912000012
-
Antoniades, C., Shirodaria, C., Warrick, N., Cai, S., de Bono, J., Lee, J., Leeson, P., Neubauer, S., Ratnatunga, C., Pillai, R., Refsum, H., Channon, K.M., 2006. 5-Methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiop-terin availability and endothelial nitric oxide synthase coupling. Circulation 114, 1193-1201. (Pubitemid 44386484)
-
(2006)
Circulation
, vol.114
, Issue.11
, pp. 1193-1201
-
-
Antoniades, C.1
Shirodaria, C.2
Warrick, N.3
Cai, S.4
De Bono, J.5
Lee, J.6
Leeson, P.7
Neubauer, S.8
Ratnatunga, C.9
Pillai, R.10
Refsum, H.11
Channon, K.M.12
-
3
-
-
0037772382
-
Compensatory phosphorylation and protein-protein interactions revealed by loss of function and gain of function mutants of multiple serine phosphorylation sites in endothelial nitric-oxide synthase
-
DOI 10.1074/jbc.M211926200
-
Bauer, P.M., Fulton, D., Boo, Y.C., Sorescu, G.P., Kemp, B.E., Jo, H., Sessa, W.C., 2003. Compensatory phosphorylation and protein-protein interactions revealed by loss of function and gain of function mutants of multiple serine phosphorylation sites in endothelial nitric-oxide synthase. J. Biol. Chem. 278, 14841-14849. (Pubitemid 36799811)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.17
, pp. 14841-14849
-
-
Bauer, P.M.1
Fulton, D.2
Boo, Y.C.3
Sorescu, G.P.4
Kemp, B.E.5
Jo, H.6
Sessa, W.C.7
-
4
-
-
0032783131
-
Oral folate enhances endothelial function in hyperhomocysteinaemic subjects
-
DOI 10.1046/j.1365-2362.1999.00527.x
-
Bellamy, M.F., McDowell, I.F., Ramsey, M.W., Brownlee, M., Newcombe, R.G., Lewis, M.J., 1999. Oral folate enhances endothelial function in hyperhomo-cysteinaemic subjects. Eur. J. Clin. Invest. 29, 659-662. (Pubitemid 29366712)
-
(1999)
European Journal of Clinical Investigation
, vol.29
, Issue.8
, pp. 659-662
-
-
Bellamy, M.F.1
McDowell, I.F.W.2
Ramsey, M.W.3
Brownlee, M.4
Newcombe, R.G.5
Lewis, M.J.6
-
5
-
-
33645796222
-
Homocysteine lowering and cardiovascular events after acute myocardial infarction
-
Bonaa, K.H., Njolstad, I., Ueland, P.M., Schirmer, H., Tverdal, A., Steigen, T., Wang, H., Nordrehaug, J.E., Arnesen, E., Rasmussen, K., 2006. Homocysteine lowering and cardiovascular events after acute myocardial infarction. N. Engl. J. Med. 354, 1578-1588.
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 1578-1588
-
-
Bonaa, K.H.1
Njolstad, I.2
Ueland, P.M.3
Schirmer, H.4
Tverdal, A.5
Steigen, T.6
Wang, H.7
Nordrehaug, J.E.8
Arnesen, E.9
Rasmussen, K.10
-
6
-
-
0142227698
-
635 produces NO without requiring intracellular calcium increase
-
DOI 10.1016/S0891-5849(03)00397-6
-
Boo, Y.C., Sorescu, G.P., Bauer, P.M., Fulton, D., Kemp, B.E., Harrison, D.G., Sessa, W.C., Jo, H., 2003. Endothelial NO synthase phosphorylated at SER635 produces NO without requiring intracellular calcium increase. Free Radical Biol. Med. 35, 729-741. (Pubitemid 37329476)
-
(2003)
Free Radical Biology and Medicine
, vol.35
, Issue.7
, pp. 729-741
-
-
Boo, Y.C.1
Sorescu, G.P.2
Bauer, P.M.3
Fulton, D.4
Kemp, B.E.5
Harrison, D.G.6
Sessa, W.C.7
Jo, H.8
-
7
-
-
0035980110
-
Hsp90 ensures the transition from the early ca2+-dependent to the late phosphorylation-dependent activation of the endothelial nitric-oxide synthase in vascular endothelial growth factor-exposed endothelial cells
-
Brouet, A., Sonveaux, P., Dessy, C., Balligand, J.L., Feron, O., 2001. Hsp90 ensures the transition from the early Ca2+-dependent to the late phosphorylation-dependent activation of the endothelial nitric-oxide synthase in vascular endothelial growth factor-exposed endothelial cells. J. Biol. Chem. 276, 32663-32669.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 32663-32669
-
-
Brouet, A.1
Sonveaux, P.2
Dessy, C.3
Balligand, J.L.4
Feron, O.5
-
8
-
-
4644367113
-
Effects of multivitamins and low-dose folic acid supplements on flow-mediated vasodilation and plasma homocysteine levels in older adults
-
DOI 10.1016/j.ahj.2004.01.023, PII S0002870304001632
-
Carlsson, C.M., Pharo, L.M., Aeschlimann, S.E., Mitchell, C., Underbakke, G., Stein, J.H., 2004. Effects of multivitamins and low-dose folic acid supplements on flow-mediated vasodilation and plasma homocysteine levels in older adults. Am. Heart J. 148, E11. (Pubitemid 39265105)
-
(2004)
American Heart Journal
, vol.148
, Issue.3
-
-
Carlsson, C.M.1
Pharo, L.M.2
Aeschlimann, S.E.3
Mitchell, C.4
Underbakke, G.5
Stein, J.H.6
-
9
-
-
0034649324
-
Improved vascular endothelial function after oral B vitamins: An effect mediated through reduced concentrations of free plasma homocysteine
-
Chambers, J.C., Ueland, P.M., Obeid, O.A., Wrigley, J., Refsum, H., Kooner, J.S., 2000. Improved vascular endothelial function after oral B vitamins: an effect mediated through reduced concentrations of free plasma homocysteine. Circulation 102, 2479-2483.
-
(2000)
Circulation
, vol.102
, pp. 2479-2483
-
-
Chambers, J.C.1
Ueland, P.M.2
Obeid, O.A.3
Wrigley, J.4
Refsum, H.5
Kooner, J.S.6
-
10
-
-
74949143633
-
Cyclin-dependent kinase 5 phosphorylates endothelial nitric oxide synthase at serine 116
-
Cho, D.H., Seo, J., Park, J.H., Jo, C., Choi, Y.J., Soh, J.W., Jo, I., 2010. Cyclin-dependent kinase 5 phosphorylates endothelial nitric oxide synthase at serine 116. Hypertension 55, 345-352.
-
(2010)
Hypertension
, vol.55
, pp. 345-352
-
-
Cho, D.H.1
Seo, J.2
Park, J.H.3
Jo, C.4
Choi, Y.J.5
Soh, J.W.6
Jo, I.7
-
11
-
-
0033542476
-
Activation of nitric oxide synthase in endothelial cells by akt-dependent phosphorylation
-
Dimmeler, S., Fleming, I., Fisslthaler, B., Hermann, C., Busse, R., Zeiher, A.M., 1999. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 399, 601-605.
-
(1999)
Nature
, vol.399
, pp. 601-605
-
-
Dimmeler, S.1
Fleming, I.2
Fisslthaler, B.3
Hermann, C.4
Busse, R.5
Zeiher, A.M.6
-
12
-
-
0035721992
-
Folate improves endothelial function in coronary artery disease: An effect mediated by reduction of intracellular superoxide?
-
Doshi, S.N., McDowell, I.F., Moat, S.J., Lang, D., Newcombe, R.G., Kredan, M.B., Lewis, M.J., Goodfellow, J., 2001. Folate improves endothelial function in coronary artery disease: an effect mediated by reduction of intracellular superoxide? Arterioscler. Thromb. Vasc. Biol. 21, 1196-1202. (Pubitemid 34215150)
-
(2001)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.21
, Issue.7
, pp. 1196-1202
-
-
Doshi, S.N.1
McDowell, I.F.W.2
Moat, S.J.3
Lang, D.4
Newcombe, R.G.5
Kredan, M.B.6
Lewis, M.J.7
Goodfellow, J.8
-
13
-
-
0036140785
-
Folic acid improves endothelial function in coronary artery disease via mechanisms largely independent of homocysteine lowering
-
DOI 10.1161/hc0102.101388
-
Doshi, S.N., McDowell, I.F., Moat, S.J., Payne, N., Durrant, H.J., Lewis, M.J., Goodfellow, J., 2002. Folic acid improves endothelial function in coronary artery disease via mechanisms largely independent of homocysteine lowering. Circulation 105, 22-26. (Pubitemid 34049137)
-
(2002)
Circulation
, vol.105
, Issue.1
, pp. 22-26
-
-
Doshi, S.N.1
McDowell, I.F.W.2
Moat, S.J.3
Payne, N.4
Durrant, H.J.5
Lewis, M.J.6
Goodfellow, J.7
-
14
-
-
22144473356
-
Effect of lowering of homocysteine levels on inflammatory markers: A randomized controlled trial
-
DOI 10.1001/archinte.165.12.1388
-
Durga, J., van Tits, L.J., Schouten, E.G., Kok, F.J., Verhoef, P., 2005. Effect of lowering of homocysteine levels on inflammatory markers: a randomized controlled trial. Arch. Intern. Med. 165, 1388-1394. (Pubitemid 40983631)
-
(2005)
Archives of Internal Medicine
, vol.165
, Issue.12
, pp. 1388-1394
-
-
Durga, J.1
Van Tits, L.J.H.2
Schouten, E.G.3
Kok, F.J.4
Verhoef, P.5
-
15
-
-
19944429119
-
Homocysteine-lowering treatment with folic acid, cobalamin, and pyridoxine does not reduce blood markers of inflammation, endothelial dysfunction, or hypercoagulability in patients with previous transient ischemic attack or stroke: A randomized substudy of the VITATOPS trial
-
DOI 10.1161/01.STR.0000150494.91762.70
-
Dusitanond, P., Eikelboom, J.W., Hankey, G.J., Thom, J., Gilmore, G., Loh, K., Yi, Q., Klijn, C.J., Langton, P., van Bockxmeer, F.M., Baker, R., Jamrozik, K., 2005. Homocysteine-lowering treatment with folic acid, cobalamin, and pyridoxine does not reduce blood markers of inflammation, endothelial dysfunction, or hypercoagulability in patients with previous transient ischemic attack or stroke: a randomized substudy of the VITATOPS trial. Stroke 36, 144-146. (Pubitemid 40054191)
-
(2005)
Stroke
, vol.36
, Issue.1
, pp. 144-146
-
-
Dusitanond, P.1
Eikelboom, J.W.2
Hankey, G.J.3
Thom, J.4
Gilmore, G.5
Loh, K.6
Yi, Q.7
Klijn, C.J.M.8
Langton, P.9
Van Bockxmeer, F.M.10
Baker, R.11
Jamrozik, K.12
-
16
-
-
49949101867
-
Mortality and cardiovascular events in patients treated with homocysteine-lowering B vitamins after coronary angiography: A randomized controlled trial
-
Ebbing, M., Bleie, O., Ueland, P.M., Nordrehaug, J.E., Nilsen, D.W., Vollset, S.E., Refsum, H., Pedersen, E.K., Nygard, O., 2008. Mortality and cardiovascular events in patients treated with homocysteine-lowering B vitamins after coronary angiography: a randomized controlled trial. JAMA 300, 795-804.
-
(2008)
JAMA
, vol.300
, pp. 795-804
-
-
Ebbing, M.1
Bleie, O.2
Ueland, P.M.3
Nordrehaug, J.E.4
Nilsen, D.W.5
Vollset, S.E.6
Refsum, H.7
Pedersen, E.K.8
Nygard, O.9
-
17
-
-
0029787241
-
Endothelial nitric oxide synthase targeting to caveolae. Specific interactions with caveolin isoforms in cardiac myocytes and endothelial cells
-
DOI 10.1074/jbc.271.37.22810
-
Feron, O., Belhassen, L., Kobzik, L., Smith, T.W., Kelly, R.A., Michel, T., 1996. Endothelial nitric oxide synthase targeting to caveolae. Specific interactions with caveolin isoforms in cardiac myocytes and endothelial cells. J. Biol. Chem. 271, 22810-22814. (Pubitemid 26304729)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.37
, pp. 22810-22814
-
-
Feron, O.1
Belhassen, L.2
Kobzik, L.3
Smith, T.W.4
Kelly, R.A.5
Michel, T.6
-
18
-
-
0035827676
-
Phosphorylation of thr(495) regulates ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity
-
Fleming, I., Fisslthaler, B., Dimmeler, S., Kemp, B.E., Busse, R., 2001. Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity. Circ. Res. 88, E68-E75.
-
(2001)
Circ. Res.
, vol.88
-
-
Fleming, I.1
Fisslthaler, B.2
Dimmeler, S.3
Kemp, B.E.4
Busse, R.5
-
19
-
-
0026071876
-
Calmodulin-dependent endothelium-derived relaxing factor/nitric oxide synthase activity is present in the particulate and cytosolic fractions of bovine aortic endothelial cells
-
Forstermann, U., Pollock, J.S., Schmidt, H.H., Heller, M., Murad, F., 1991. Calmodulin-dependent endothelium-derived relaxing factor/nitric oxide synthase activity is present in the particulate and cytosolic fractions of bovine aortic endothelial cells. Proc. Natl. Acad. Sci. USA 88, 1788-1792. (Pubitemid 21916311)
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, Issue.5
, pp. 1788-1792
-
-
Forstermann, U.1
Pollock, J.S.2
Schmidt, H.H.H.W.3
Heller, M.4
Murad, F.5
-
20
-
-
0037040278
-
Localization of endothelial nitric-oxide synthase phosphorylated on serine 1179 and nitric oxide in golgi and plasma membrane defines the existence of two pools of active enzyme
-
DOI 10.1074/jbc.M106302200
-
Fulton, D., Fontana, J., Sowa, G., Gratton, J.P., Lin, M., Li, K.X., Michell, B., Kemp, B.E., Rodman, D., Sessa, W.C., 2002. Localization of endothelial nitric-oxide synthase phosphorylated on serine 1179 and nitric oxide in Golgi and plasma membrane defines the existence of two pools of active enzyme. J. Biol. Chem. 277, 4277-4284. (Pubitemid 34968692)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.6
, pp. 4277-4284
-
-
Fulton, D.1
Fontana, J.2
Sowa, G.3
Gratton, J.-P.4
Lin, M.5
Li, K.-X.6
Michell, B.7
Kemp, B.E.8
Rodman, D.9
Sessa, W.C.10
-
21
-
-
0033542414
-
Regulation of endothelium-derived nitric oxide production by the protein kinase akt
-
Fulton, D., Gratton, J.P., McCabe, T.J., Fontana, J., Fujio, Y., Walsh, K., Franke, T.F., Papapetropoulos, A., Sessa, W.C., 1999. Regulation of endothelium-derived nitric oxide production by the protein kinase Akt. Nature 399, 597-601.
-
(1999)
Nature
, vol.399
, pp. 597-601
-
-
Fulton, D.1
Gratton, J.P.2
McCabe, T.J.3
Fontana, J.4
Fujio, Y.5
Walsh, K.6
Franke, T.F.7
Papapetropoulos, A.8
Sessa, W.C.9
-
22
-
-
0035192750
-
Post-translational control of endothelial nitric oxide synthase: Why isn't calcium/calmodulin enough?
-
Fulton, D., Gratton, J.P., Sessa, W.C., 2001. Post-translational control of endothelial nitric oxide synthase: why isn't calcium/calmodulin enough? J. Pharmacol. Exp. Ther. 299, 818-824. (Pubitemid 33104947)
-
(2001)
Journal of Pharmacology and Experimental Therapeutics
, vol.299
, Issue.3
, pp. 818-824
-
-
Fulton, D.1
Gratton, J.-P.2
Sessa, W.C.3
-
23
-
-
83655167072
-
Role of uncoupled endothelial nitric oxide synthase in abdominal aortic aneurysm formation: Treatment with folic acid
-
Gao, L., Siu, K.L., Chalupsky, K., Nguyen, A., Chen, P., Weintraub, N.L., Galis, Z., Cai, H., 2012. Role of uncoupled endothelial nitric oxide synthase in abdominal aortic aneurysm formation: treatment with folic acid. Hypertension 59, 158-166.
-
(2012)
Hypertension
, vol.59
, pp. 158-166
-
-
Gao, L.1
Siu, K.L.2
Chalupsky, K.3
Nguyen, A.4
Chen, P.5
Weintraub, N.L.6
Galis, Z.7
Cai, H.8
-
24
-
-
0009621605
-
Dynamic activation of endothelial nitric oxide synthase by Hsp90
-
DOI 10.1038/33934
-
Garcia-Cardena, G., Fan, R., Shah, V., Sorrentino, R., Cirino, G., Papapetropoulos, A., Sessa, W.C., 1998. Dynamic activation of endothelial nitric oxide synthase by Hsp90. Nature 392, 821-824. (Pubitemid 28225323)
-
(1998)
Nature
, vol.392
, Issue.6678
, pp. 821-824
-
-
Garcia-Cardena, G.1
Fan, R.2
Shah, V.3
Sorrentino, R.4
Cirino, G.5
Papapetropoulos, A.6
Sessa, W.C.7
-
25
-
-
0034698050
-
Reconstitution of an endothelial nitric-oxide synthase (eNOS), hsp90, and caveolin-1 complex in vitro: Evidence that hsp90 facilitates calmodulin stimulated displacement of eNOS from caveolin-1
-
DOI 10.1074/jbc.M001644200
-
Gratton, J.P., Fontana, J., O'Connor, D.S., Garcia-Cardena, G., McCabe, T.J., Sessa, W.C., 2000. Reconstitution of an endothelial nitric-oxide synthase (eNOS), hsp90, and caveolin-1 complex in vitro. Evidence that hsp90 facilitates calmodulin stimulated displacement of eNOS from caveolin-1. J. Biol. Chem. 275, 22268-22272. (Pubitemid 30621809)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.29
, pp. 22268-22272
-
-
Gratton, J.-P.1
Fontana, J.2
O'Connor, D.S.3
Garcia-Cardena, G.4
McCabe, T.J.5
Sessa, W.C.6
-
26
-
-
77955656519
-
B vitamins in patients with recent transient ischaemic attack or stroke in the VITAmins TO prevent stroke (VITATOPS) trial: A randomised, double-blind, parallel, placebo-controlled trial
-
Hankey, G.J., Eikelboom, J.W., Baker, R.I., Gelavis, A., Hickling, S.C., Jamrozik, K., et al., 2010. B vitamins in patients with recent transient ischaemic attack or stroke in the VITAmins TO Prevent Stroke (VITATOPS) trial: a randomised, double-blind, parallel, placebo-controlled trial. Lancet Neurol. 9, 855-865.
-
(2010)
Lancet Neurol.
, vol.9
, pp. 855-865
-
-
Hankey, G.J.1
Eikelboom, J.W.2
Baker, R.I.3
Gelavis, A.4
Hickling, S.C.5
Jamrozik, K.6
-
27
-
-
0030853953
-
Direct interaction of endothelial nitric-oxide synthase and caveolin-1 inhibits synthase activity
-
DOI 10.1074/jbc.272.30.18522
-
Ju, H., Zou, R., Venema, V.J., Venema, R.C., 1997. Direct interaction of endothelial nitric-oxide synthase and caveolin-1 inhibits synthase activity. J. Biol. Chem. 272, 18522-18525. (Pubitemid 27318186)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.30
, pp. 18522-18525
-
-
Ju, H.1
Zou, R.2
Venema, V.J.3
Venema, R.C.4
-
28
-
-
22144471207
-
No effect of folic acid supplementation in the course of 1 year on haemostasis markers and C-reactive protein in older adults
-
DOI 10.1160/TH04-08-0524
-
Klerk, M., Durga, J., Schouten, E.G., Kluft, C., Kok, F.J., Verhoef, P., 2005. No effect of folic acid supplementation in the course of 1 year on haemostasis markers and C-reactive protein in older adults. Thromb. Haemostasis 94, 96-100. (Pubitemid 40974712)
-
(2005)
Thrombosis and Haemostasis
, vol.94
, Issue.1
, pp. 96-100
-
-
Klerk, M.1
Durga, J.2
Schouten, E.G.3
Kluft, C.4
Kok, F.J.5
Verhoef, P.6
-
29
-
-
0038486928
-
Protein interactions with nitric oxide synthases: Controlling the right time, the right place, and the right amount of nitric oxide
-
Kone, B.C., Kuncewicz, T., Zhang, W., Yu, Z.Y., 2003. Protein interactions with nitric oxide synthases: controlling the right time, the right place, and the right amount of nitric oxide. Am. J. Physiol. Renal Physiol. 285, F178-F190. (Pubitemid 36871190)
-
(2003)
American Journal of Physiology - Renal Physiology
, vol.285
, Issue.2
-
-
Kone, B.C.1
Kuncewicz, T.2
Zhang, W.3
Yu, Z.-Y.4
-
30
-
-
0037166321
-
Disabling a C-terminal autoinhibitory control element in endothelial nitric-oxide synthase by phosphorylation provides a molecular explanation for activation of vascular NO synthesis by diverse physiological stimuli
-
DOI 10.1074/jbc.M200258200
-
Lane, P., Gross, S.S., 2002. Disabling a C-terminal autoinhibitory control element in endothelial nitric-oxide synthase by phosphorylation provides a molecular explanation for activation of vascular NO synthesis by diverse physiological stimuli. J. Biol. Chem. 277, 19087-19094. (Pubitemid 34952474)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.21
, pp. 19087-19094
-
-
Lane, P.1
Gross, S.S.2
-
31
-
-
35548954714
-
Role of eNOS phosphorylation at Ser-116 in regulation of eNOS activity in endothelial cells
-
DOI 10.1016/j.vph.2007.07.001, PII S153718910700119X
-
Li, C., Ruan, L., Sood, S.G., Papapetropoulos, A., Fulton, D., Venema, R.C., 2007. Role of eNOS phosphorylation at Ser-116 in regulation of eNOS activity in endothelial cells. Vascul. Pharmacol. 47, 257-264. (Pubitemid 350017809)
-
(2007)
Vascular Pharmacology
, vol.47
, Issue.5-6
, pp. 257-264
-
-
Li, C.1
Ruan, L.2
Sood, S.G.3
Papapetropoulos, A.4
Fulton, D.5
Venema, R.C.6
-
32
-
-
33645753544
-
Homocysteine lowering with folic acid and B vitamins in vascular disease
-
Lonn, E., Yusuf, S., Arnold, M.J., Sheridan, P., Pogue, J., Micks, M., McQueen, M.J., Probstfield, J., Fodor, G., Held, C., Genest Jr., J., 2006. Homocysteine lowering with folic acid and B vitamins in vascular disease. N. Engl. J. Med. 354, 1567-1577.
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 1567-1577
-
-
Lonn, E.1
Yusuf, S.2
Arnold, M.J.3
Sheridan, P.4
Pogue, J.5
Micks, M.6
McQueen, M.J.7
Probstfield, J.8
Fodor, G.9
Held, C.10
Genest Jr., J.11
-
33
-
-
0034054493
-
Enhanced electron flux and reduced calmodulin dissociation may explain 'calcium-independent' eNOS activation by phosphorylation
-
DOI 10.1074/jbc.275.9.6123
-
McCabe, T.J., Fulton, D., Roman, L.J., Sessa, W.C., 2000. Enhanced electron flux and reduced calmodulin dissociation may explain "calcium-independent," eNOS activation by phosphorylation. J. Biol. Chem. 275, 6123-6128. (Pubitemid 30129896)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.9
, pp. 6123-6128
-
-
McCabe, T.J.1
Fulton, D.2
Roman, L.J.3
Sessa, W.C.4
-
34
-
-
0030953208
-
2+- calmodulin and caveolin
-
DOI 10.1074/jbc.272.25.15583
-
Michel, J.B., Feron, O., Sacks, D., Michel, T., 1997a. Reciprocal regulation of endothelial nitric-oxide synthase by Ca2+-calmodulin and caveolin. J. Biol. Chem. 272, 15583-15586. (Pubitemid 27265522)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.25
, pp. 15583-15586
-
-
Michel, J.B.1
Feron, O.2
Sacks, D.3
Michel, T.4
-
35
-
-
0030770629
-
Caveolin versus calmodulin. Counterbalancing allosteric modulators of endothelial nitric oxide synthase
-
DOI 10.1074/jbc.272.41.25907
-
Michel, J.B., Feron, O., Sase, K., Prabhakar, P., Michel, T., 1997b. Caveolin versus calmodulin. Counterbalancing allosteric modulators of endothelial nitric oxide synthase. J. Biol. Chem. 272, 25907-25912. (Pubitemid 27438916)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.41
, pp. 25907-25912
-
-
Michel, J.B.1
Feron, O.2
Sase, K.3
Prabhakar, P.4
Michel, T.5
-
36
-
-
0036829884
-
Identification of regulatory sites of phosphorylation of the bovine endothelial nitric-oxide synthase at Serine 617 and Serine 635
-
DOI 10.1074/jbc.M205144200
-
Michell, B.J., Harris, M.B., Chen, Z.P., Ju, H., Venema, V.J., Blackstone, M.A., Huang, W., Venema, R.C., Kemp, B.E., 2002. Identification of regulatory sites of phosphor-ylation of the bovine endothelial nitric-oxide synthase at serine 617 and serine 635. J. Biol. Chem. 277, 42344-42351. (Pubitemid 35257555)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.44
, pp. 42344-42351
-
-
Michell, B.J.1
Brennan Harris, M.2
Chen, Z.-P.3
Ju, H.4
Venema, V.J.5
Blackstone, M.A.6
Huang, W.7
Venema, R.C.8
Kemp, B.E.9
-
37
-
-
30444458698
-
Folic acid reverses endothelial dysfunction induced by inhibition of tetrahydrobiopterin biosynthesis
-
DOI 10.1016/j.ejphar.2005.11.047, PII S0014299905012501
-
Moat, S.J., Clarke, Z.L., Madhavan, A.K., Lewis, M.J., Lang, D., 2006a. Folic acid reverses endothelial dysfunction induced by inhibition of tetrahydrobiopterin biosynthesis. Eur. J. Pharmacol. 530, 250-258. (Pubitemid 43075496)
-
(2006)
European Journal of Pharmacology
, vol.530
, Issue.3
, pp. 250-258
-
-
Moat, S.J.1
Clarke, Z.L.2
Madhavan, A.K.3
Lewis, M.J.4
Lang, D.5
-
38
-
-
33750728400
-
High- but not low-dose folic acid improves endothelial function in coronary artery disease
-
DOI 10.1111/j.1365-2362.2006.01739.x
-
Moat, S.J., Madhavan, A., Taylor, S.Y., Payne, N., Allen, R.H., Stabler, S.P., Goodfellow, J., McDowell, I.F., Lewis, M.J., Lang, D., 2006b. High-but not low-dose folic acid improves endothelial function in coronary artery disease. Eur. J. Clin. Invest. 36, 850-859. (Pubitemid 44707084)
-
(2006)
European Journal of Clinical Investigation
, vol.36
, Issue.12
, pp. 850-859
-
-
Moat, S.J.1
Madhavan, A.2
Taylor, S.Y.3
Payne, N.4
Allen, R.H.5
Stabler, S.P.6
Goodfellow, J.7
McDowell, I.F.W.8
Lewis, M.J.9
Lang, D.10
-
39
-
-
77649275766
-
DeltaPKC inhibition or varepsilon PKC activation repairs endothelial vascular dysfunction by regulating eNOS post-translational modification
-
Monti, M., Donnini, S., Giachetti, A., Mochly-Rosen, D., Ziche, M., 2010. deltaPKC inhibition or varepsilon PKC activation repairs endothelial vascular dysfunction by regulating eNOS post-translational modification. J. Mol. Cell Cardiol. 48, 746-756.
-
(2010)
J. Mol. Cell Cardiol.
, vol.48
, pp. 746-756
-
-
Monti, M.1
Donnini, S.2
Giachetti, A.3
Mochly-Rosen, D.4
Ziche, M.5
-
40
-
-
33846392950
-
Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation
-
DOI 10.1016/j.yjmcc.2006.05.023, PII S0022282806005888
-
Mount, P.F., Kemp, B.E., Power, D.A., 2007. Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation. J. Mol. Cell Cardiol. 42, 271-279. (Pubitemid 46135596)
-
(2007)
Journal of Molecular and Cellular Cardiology
, vol.42
, Issue.2
, pp. 271-279
-
-
Mount, P.F.1
Kemp, B.E.2
Power, D.A.3
-
41
-
-
62349112228
-
Effect of uncoupling endothelial nitric oxide synthase on calcium homeostasis in aged porcine endothelial cells
-
Perrier, E., Fournet-Bourguignon, M.P., Royere, E., Molez, S., Reure, H., Lesage, L., Gosgnach, W., Frapart, Y., Boucher, J.L., Villeneuve, N., Vilaine, J.P., 2009. Effect of uncoupling endothelial nitric oxide synthase on calcium homeostasis in aged porcine endothelial cells. Cardiovasc. Res. 82, 133-142.
-
(2009)
Cardiovasc. Res.
, vol.82
, pp. 133-142
-
-
Perrier, E.1
Fournet-Bourguignon, M.P.2
Royere, E.3
Molez, S.4
Reure, H.5
Lesage, L.6
Gosgnach, W.7
Frapart, Y.8
Boucher, J.L.9
Villeneuve, N.10
Vilaine, J.P.11
-
42
-
-
80052758036
-
ENOS activation and NO function: Structural motifs responsible for the posttranslational control of endothelial nitric oxide synthase activity
-
Rafikov, R., Fonseca, F.V., Kumar, S., Pardo, D., Darragh, C., Elms, S., Fulton, D., Black, S.M., 2011. eNOS activation and NO function: structural motifs responsible for the posttranslational control of endothelial nitric oxide synthase activity. J. Endocrinol. 210, 271-284.
-
(2011)
J. Endocrinol.
, vol.210
, pp. 271-284
-
-
Rafikov, R.1
Fonseca, F.V.2
Kumar, S.3
Pardo, D.4
Darragh, C.5
Elms, S.6
Fulton, D.7
Black, S.M.8
-
43
-
-
0029561612
-
Myristoylation of endothelial cell nitric oxide synthase is important for extracellular release of nitric oxide
-
DOI 10.1007/BF01076076
-
Sakoda, T., Hirata, K., Kuroda, R., Miki, N., Suematsu, M., Kawashima, S., Yokoyama, M., 1995. Myristoylation of endothelial cell nitric oxide synthase is important for extracellular release of nitric oxide. Mol. Cell. Biochem. 152, 143-148. (Pubitemid 26006136)
-
(1995)
Molecular and Cellular Biochemistry
, vol.152
, Issue.2
, pp. 143-148
-
-
Sakoda, T.1
Hirata, K.-I.2
Kuroda, R.3
Miki, N.4
Suematsu, M.5
Katiashima, S.6
Yokoyama, M.7
-
44
-
-
0029022062
-
The golgi association of endothelial nitric oxide synthase is necessary for the efficient synthesis of nitric oxide
-
Sessa, W.C., Garcia-Cardena, G., Liu, J., Keh, A., Pollock, J.S., Bradley, J., Thiru, S., Braverman, I.M., Desai, K.M., 1995. The Golgi association of endothelial nitric oxide synthase is necessary for the efficient synthesis of nitric oxide. J. Biol. Chem. 270, 17641-17644.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 17641-17644
-
-
Sessa, W.C.1
Garcia-Cardena, G.2
Liu, J.3
Keh, A.4
Pollock, J.S.5
Bradley, J.6
Thiru, S.7
Braverman, I.M.8
Desai, K.M.9
-
45
-
-
77955847141
-
Folic acid consumption reduces resistin level and restores blunted acetylcholine-induced aortic relaxation in obese/diabetic mice
-
Seto, S.W., Lam, T.Y., Or, P.M., Lee, W.Y., Au, A.L., Poon, C.C., Li, R.W., Chan, S.W., Yeung, J.H., Leung, G.P., Lee, S.M., Ngai, S.M., Kwan, Y.W., 2010. Folic acid consumption reduces resistin level and restores blunted acetylcholine-induced aortic relaxation in obese/diabetic mice. J. Nutr. Biochem. 21, 872-880.
-
(2010)
J. Nutr. Biochem.
, vol.21
, pp. 872-880
-
-
Seto, S.W.1
Lam, T.Y.2
Or, P.M.3
Lee, W.Y.4
Au, A.L.5
Poon, C.C.6
Li, R.W.7
Chan, S.W.8
Yeung, J.H.9
Leung, G.P.10
Lee, S.M.11
Ngai, S.M.12
Kwan, Y.W.13
-
46
-
-
0036199988
-
Regulation of endothelial nitric oxide synthase: Location, location, location
-
DOI 10.1146/annurev.physiol.64.081501.155952
-
Shaul, P.W., 2002. Regulation of endothelial nitric oxide synthase: location, location, location. Annu. Rev. Physiol. 64, 749-774. (Pubitemid 34259248)
-
(2002)
Annual Review of Physiology
, vol.64
, pp. 749-774
-
-
Shaul, P.W.1
-
47
-
-
0029664995
-
Acylation targets endothelial nitric-oxide synthase to plasmalemmal caveolae
-
DOI 10.1074/jbc.271.11.6518
-
Shaul, P.W., Smart, E.J., Robinson, L.J., German, Z., Yuhanna, I.S., Ying, Y., Anderson, R.G., Michel, T., 1996. Acylation targets emdothelial nitric-oxide synthase to plasmalemmal caveolae. J. Biol. Chem. 271, 6518-6522. (Pubitemid 26095467)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.11
, pp. 6518-6522
-
-
Shaul, P.W.1
Smart, E.J.2
Robinson, L.J.3
German, Z.4
Yuhanna, I.S.5
Ying, Y.6
Anderson, R.G.W.7
Michel, T.8
-
48
-
-
34247578183
-
Global improvement of vascular function and redox state with low-dose folic acid: Implications for folate therapy in patients with coronary artery disease
-
DOI 10.1161/CIRCULATIONAHA.106.679084
-
Shirodaria, C., Antoniades, C., Lee, J., Jackson, C.E., Robson, M.D., Francis, J.M., Moat, S.J., Ratnatunga, C., Pillai, R., Refsum, H., Neubauer, S., Channon, K.M., 2007. Global improvement of vascular function and redox state with low-dose folic acid: implications for folate therapy in patients with coronary artery disease. Circulation 115, 2262-2270. (Pubitemid 46685894)
-
(2007)
Circulation
, vol.115
, Issue.17
, pp. 2262-2270
-
-
Shirodaria, C.1
Antoniades, C.2
Lee, J.3
Jackson, C.E.4
Robson, M.D.5
Francis, J.M.6
Moat, S.J.7
Ratnatunga, C.8
Pillai, R.9
Refsum, H.10
Neubauer, S.11
Channon, K.M.12
-
49
-
-
0033529678
-
Trafficking of endothelial nitric-oxide synthase in living cells. Quantitative evidence supporting the role of palmitoylation as a kinetic trapping mechanism limiting membrane diffusion
-
Sowa, G., Liu, J., Papapetropoulos, A., Rex-Haffner, M., Hughes, T.E., Sessa, W.C., 1999. Trafficking of endothelial nitric-oxide synthase in living cells. Quantitative evidence supporting the role of palmitoylation as a kinetic trapping mechanism limiting membrane diffusion. J. Biol. Chem. 274, 22524-22531.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 22524-22531
-
-
Sowa, G.1
Liu, J.2
Papapetropoulos, A.3
Rex-Haffner, M.4
Hughes, T.E.5
Sessa, W.C.6
-
50
-
-
0141888365
-
NOS 3 subcellular localization in the regulation of nitric oxide production
-
DOI 10.1046/j.1365-201X.2003.01181.x
-
Sullivan, J.C., Pollock, J.S., 2003. NOS 3 subcellular localization in the regulation of nitric oxide production. Acta Physiol. Scand. 179, 115-122. (Pubitemid 37249245)
-
(2003)
Acta Physiologica Scandinavica
, vol.179
, Issue.2
, pp. 115-122
-
-
Sullivan, J.C.1
Pollock, J.S.2
-
51
-
-
0043234527
-
Synergistic activation of endothelial nitric-oxide synthase (eNOS) by HSP90 and Akt. Calcium-independent eNOS activation involves formation of an HSP90-Akt-CaM-bound eNOS complex
-
DOI 10.1074/jbc.M304471200
-
Takahashi, S., Mendelsohn, M.E., 2003. Synergistic activation of endothelial nitric-oxide synthase (eNOS) by HSP90 and Akt: calcium-independent eNOS activation involves formation of an HSP90-Akt-CaM-bound eNOS complex. J. Biol. Chem. 278, 30821-30827. (Pubitemid 36994590)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.33
, pp. 30821-30827
-
-
Takahashi, S.1
Mendelsohn, M.E.2
-
52
-
-
1342309318
-
Lowering Homocysteine in Patients with Ischemic Stroke to Prevent Recurrent Stroke, Myocardial Infarction, and Death: The Vitamin Intervention for Stroke Prevention (VISP) Randomized Controlled Trial
-
DOI 10.1001/jama.291.5.565
-
Toole, J.F., Malinow, M.R., Chambless, L.E., Spence, J.D., Pettigrew, L.C., Howard, V.J., Sides, E.G., Wang, C.H., Stampfer, M., 2004. Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial. JAMA 291, 565-575. (Pubitemid 38500310)
-
(2004)
Journal of the American Medical Association
, vol.291
, Issue.5
, pp. 565-575
-
-
Toole, J.F.1
Malinow, M.R.2
Chambless, L.E.3
Spence, J.D.4
Pettigrew, L.C.5
Howard, V.J.6
Sides, E.G.7
Wang, C.-H.8
Stampfer, M.9
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