-
1
-
-
33745133006
-
Extrafollicular activation of lymph node B cells by antigen-bearing dendritic cells
-
Qi H, Egen JG, Huang AY, Germain RN. Extrafollicular activation of lymph node B cells by antigen-bearing dendritic cells. Science 2006;312:1672-1676.
-
(2006)
Science
, vol.312
, pp. 1672-1676
-
-
Qi, H.1
Egen, J.G.2
Huang, A.Y.3
Germain, R.N.4
-
2
-
-
78049287668
-
The tipping points in the initiation of B cell signalling: how small changes make big differences
-
Pierce SK, Liu W. The tipping points in the initiation of B cell signalling: how small changes make big differences. Nat Rev Immunol 2010;10:767-777.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 767-777
-
-
Pierce, S.K.1
Liu, W.2
-
3
-
-
43049165459
-
New insights into the early molecular events underlying B cell activation
-
Harwood NE, Batista FD. New insights into the early molecular events underlying B cell activation. Immunity 2008;28:609-619.
-
(2008)
Immunity
, vol.28
, pp. 609-619
-
-
Harwood, N.E.1
Batista, F.D.2
-
4
-
-
33646137152
-
Immunological synapse and microclusters: the site for recognition and activation of T cells
-
Saito T, Yokosuka T. Immunological synapse and microclusters: the site for recognition and activation of T cells. Curr Opin Immunol 2006;18:305-313.
-
(2006)
Curr Opin Immunol
, vol.18
, pp. 305-313
-
-
Saito, T.1
Yokosuka, T.2
-
6
-
-
18244397166
-
Actin depolymerization transduces the strength of B-cell receptor stimulation
-
Hao S, August A. Actin depolymerization transduces the strength of B-cell receptor stimulation. Mol Biol Cell 2005;16:2275-2284.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 2275-2284
-
-
Hao, S.1
August, A.2
-
7
-
-
33748612196
-
The Nck-interacting kinase phosphorylates ERM proteins for formation of lamellipodium by growth factors
-
Baumgartner M, et al. The Nck-interacting kinase phosphorylates ERM proteins for formation of lamellipodium by growth factors. Proc Natl Acad Sci USA 2006;103:13391-13396.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 13391-13396
-
-
Baumgartner, M.1
-
8
-
-
0344826472
-
Chemokine stimulation of human peripheral blood T lymphocytes induces rapid dephosphorylation of ERM proteins, which facilitates loss of microvilli and polarization
-
Brown MJ, et al. Chemokine stimulation of human peripheral blood T lymphocytes induces rapid dephosphorylation of ERM proteins, which facilitates loss of microvilli and polarization. Blood 2003;102:3890-3899.
-
(2003)
Blood
, vol.102
, pp. 3890-3899
-
-
Brown, M.J.1
-
9
-
-
79954991429
-
Conformational switching in ezrin regulates morphological and cytoskeletal changes required for B cell chemotaxis
-
Parameswaran N, Matsui K, Gupta N. Conformational switching in ezrin regulates morphological and cytoskeletal changes required for B cell chemotaxis. J Immunol 2011;186:4088-4097.
-
(2011)
J Immunol
, vol.186
, pp. 4088-4097
-
-
Parameswaran, N.1
Matsui, K.2
Gupta, N.3
-
10
-
-
1542377326
-
ERM proteins regulate cytoskeleton relaxation promoting T cell-APC conjugation
-
Faure S, et al. ERM proteins regulate cytoskeleton relaxation promoting T cell-APC conjugation. Nat Immunol 2004;5:272-279.
-
(2004)
Nat Immunol
, vol.5
, pp. 272-279
-
-
Faure, S.1
-
11
-
-
33744494534
-
Quantitative proteomic analysis of B cell lipid rafts reveals that ezrin regulates antigen receptor-mediated lipid raft dynamics
-
Gupta N, Wollscheid B, Watts JD, Scheer B, Aebersold R, DeFranco AL. Quantitative proteomic analysis of B cell lipid rafts reveals that ezrin regulates antigen receptor-mediated lipid raft dynamics. Nat Immunol 2006;7:625-633.
-
(2006)
Nat Immunol
, vol.7
, pp. 625-633
-
-
Gupta, N.1
Wollscheid, B.2
Watts, J.D.3
Scheer, B.4
Aebersold, R.5
DeFranco, A.L.6
-
12
-
-
77953550608
-
Spatiotemporal control of cyclic AMP immunomodulation through the PKA-Csk inhibitory pathway is achieved by anchoring to an Ezrin-EBP50-PAG scaffold in effector T cells
-
Cornez I, Tasken K. Spatiotemporal control of cyclic AMP immunomodulation through the PKA-Csk inhibitory pathway is achieved by anchoring to an Ezrin-EBP50-PAG scaffold in effector T cells. FEBS Lett 2010;584:2681-2688.
-
(2010)
FEBS Lett
, vol.584
, pp. 2681-2688
-
-
Cornez, I.1
Tasken, K.2
-
13
-
-
84874284008
-
Spatial coupling of JNK activation to the B cell antigen receptor by tyrosine-phosphorylated ezrin
-
Parameswaran N, Enyindah-Asonye G, Bagheri N, Shah NB, Gupta N. Spatial coupling of JNK activation to the B cell antigen receptor by tyrosine-phosphorylated ezrin. J Immunol 2013;190:2017-2026.
-
(2013)
J Immunol
, vol.190
, pp. 2017-2026
-
-
Parameswaran, N.1
Enyindah-Asonye, G.2
Bagheri, N.3
Shah, N.B.4
Gupta, N.5
-
14
-
-
0037376772
-
A role for moesin in polarity
-
Miller KG. A role for moesin in polarity. Trends Cell Biol 2003;13:165-168.
-
(2003)
Trends Cell Biol
, vol.13
, pp. 165-168
-
-
Miller, K.G.1
-
15
-
-
3042704362
-
The C. elegans ezrin-radixin-moesin protein ERM-1 is necessary for apical junction remodelling and tubulogenesis in the intestine
-
Van Furden D, Johnson K, Segbert C, Bossinger O. The C. elegans ezrin-radixin-moesin protein ERM-1 is necessary for apical junction remodelling and tubulogenesis in the intestine. Dev Biol 2004;272:262-276.
-
(2004)
Dev Biol
, vol.272
, pp. 262-276
-
-
Van Furden, D.1
Johnson, K.2
Segbert, C.3
Bossinger, O.4
-
17
-
-
0034524664
-
ERM-Merlin and EBP50 protein families in plasma membrane organization and function
-
Bretscher A, Chambers D, Nguyen R, Reczek D. ERM-Merlin and EBP50 protein families in plasma membrane organization and function. Annu Rev Cell Dev Biol 2000;16:113-143.
-
(2000)
Annu Rev Cell Dev Biol
, vol.16
, pp. 113-143
-
-
Bretscher, A.1
Chambers, D.2
Nguyen, R.3
Reczek, D.4
-
19
-
-
84861312738
-
Ezrin ubiquitylation by the E3 ubiquitin ligase, WWP1, and consequent regulation of hepatocyte growth factor receptor activity
-
Zaarour RF, et al. Ezrin ubiquitylation by the E3 ubiquitin ligase, WWP1, and consequent regulation of hepatocyte growth factor receptor activity. PLoS ONE 2012;7:e37490.
-
(2012)
PLoS ONE
, vol.7
-
-
Zaarour, R.F.1
-
20
-
-
0034724536
-
Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain
-
Pearson MA, Reczek D, Bretscher A, Karplus PA. Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain. Cell 2000;101:259-270.
-
(2000)
Cell
, vol.101
, pp. 259-270
-
-
Pearson, M.A.1
Reczek, D.2
Bretscher, A.3
Karplus, P.A.4
-
21
-
-
0034283003
-
Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain
-
Hamada K, Shimizu T, Matsui T, Tsukita S, Hakoshima T. Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain. EMBO J 2000;19:4449-4462.
-
(2000)
EMBO J
, vol.19
, pp. 4449-4462
-
-
Hamada, K.1
Shimizu, T.2
Matsui, T.3
Tsukita, S.4
Hakoshima, T.5
-
22
-
-
0035912664
-
The 2.7 A crystal structure of the activated FERM domain of moesin: an analysis of structural changes on activation
-
Edwards SD, Keep NH. The 2.7 A crystal structure of the activated FERM domain of moesin: an analysis of structural changes on activation. Biochemistry 2001;40:7061-7068.
-
(2001)
Biochemistry
, vol.40
, pp. 7061-7068
-
-
Edwards, S.D.1
Keep, N.H.2
-
23
-
-
0038136972
-
Structure of the active N-terminal domain of Ezrin. Conformational and mobility changes identify keystone interactions
-
Smith WJ, Nassar N, Bretscher A, Cerione RA, Karplus PA. Structure of the active N-terminal domain of Ezrin. Conformational and mobility changes identify keystone interactions. J Biol Chem 2003;278:4949-4956.
-
(2003)
J Biol Chem
, vol.278
, pp. 4949-4956
-
-
Smith, W.J.1
Nassar, N.2
Bretscher, A.3
Cerione, R.A.4
Karplus, P.A.5
-
24
-
-
0028800154
-
Identification of a phosphatidylinositol-4,5-bisphosphate-binding domain in the N-terminal region of ezrin
-
Niggli V, Andreoli C, Roy C, Mangeat P. Identification of a phosphatidylinositol-4, 5-bisphosphate-binding domain in the N-terminal region of ezrin. FEBS Lett 1995;376:172-176.
-
(1995)
FEBS Lett
, vol.376
, pp. 172-176
-
-
Niggli, V.1
Andreoli, C.2
Roy, C.3
Mangeat, P.4
-
25
-
-
0032583447
-
C-terminal threonine phosphorylation activates ERM proteins to link the cell's cortical lipid bilayer to the cytoskeleton
-
Simons PC, Pietromonaco SF, Reczek D, Bretscher A, Elias L. C-terminal threonine phosphorylation activates ERM proteins to link the cell's cortical lipid bilayer to the cytoskeleton. Biochem Biophys Res Commun 1998;253:561-565.
-
(1998)
Biochem Biophys Res Commun
, vol.253
, pp. 561-565
-
-
Simons, P.C.1
Pietromonaco, S.F.2
Reczek, D.3
Bretscher, A.4
Elias, L.5
-
26
-
-
57649194806
-
Characterization of the Ca2 + -regulated ezrin-S100P interaction and its role in tumor cell migration
-
Austermann J, Nazmi AR, Muller-Tidow C, Gerke V. Characterization of the Ca2 + -regulated ezrin-S100P interaction and its role in tumor cell migration. J Biol Chem 2008;283:29331-29340.
-
(2008)
J Biol Chem
, vol.283
, pp. 29331-29340
-
-
Austermann, J.1
Nazmi, A.R.2
Muller-Tidow, C.3
Gerke, V.4
-
27
-
-
0029121577
-
Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site
-
Gary R, Bretscher A. Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site. Mol Biol Cell 1995;6:1061-1075.
-
(1995)
Mol Biol Cell
, vol.6
, pp. 1061-1075
-
-
Gary, R.1
Bretscher, A.2
-
28
-
-
0032498528
-
Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association
-
Matsui T, et al. Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association. J Cell Biol 1998;140:647-657.
-
(1998)
J Cell Biol
, vol.140
, pp. 647-657
-
-
Matsui, T.1
-
29
-
-
21844467495
-
G protein-coupled receptor kinase 2-mediated phosphorylation of ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton
-
Cant SH, Pitcher JA. G protein-coupled receptor kinase 2-mediated phosphorylation of ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton. Mol Biol Cell 2005;16:3088-3099.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 3088-3099
-
-
Cant, S.H.1
Pitcher, J.A.2
-
30
-
-
70449377127
-
Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis
-
Parisiadou L, et al. Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis. J Neurosci 2009;29:13971-13980.
-
(2009)
J Neurosci
, vol.29
, pp. 13971-13980
-
-
Parisiadou, L.1
-
31
-
-
63849151166
-
LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation
-
Belkina NV, Liu Y, Hao JJ, Karasuyama H, Shaw S. LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation. Proc Natl Acad Sci USA 2009;106:4707-4712.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 4707-4712
-
-
Belkina, N.V.1
Liu, Y.2
Hao, J.J.3
Karasuyama, H.4
Shaw, S.5
-
32
-
-
0032571406
-
Protein kinase C-theta phosphorylation of moesin in the actin-binding sequence
-
Pietromonaco SF, Simons PC, Altman A, Elias L. Protein kinase C-theta phosphorylation of moesin in the actin-binding sequence. J Biol Chem 1998;273:7594-7603.
-
(1998)
J Biol Chem
, vol.273
, pp. 7594-7603
-
-
Pietromonaco, S.F.1
Simons, P.C.2
Altman, A.3
Elias, L.4
-
33
-
-
0032550225
-
Association of the myosin-binding subunit of myosin phosphatase and moesin: dual regulation of moesin phosphorylation by Rho-associated kinase and myosin phosphatase
-
Fukata Y, Kimura K, Oshiro N, Saya H, Matsuura Y, Kaibuchi K. Association of the myosin-binding subunit of myosin phosphatase and moesin: dual regulation of moesin phosphorylation by Rho-associated kinase and myosin phosphatase. J Cell Biol 1998;141:409-418.
-
(1998)
J Cell Biol
, vol.141
, pp. 409-418
-
-
Fukata, Y.1
Kimura, K.2
Oshiro, N.3
Saya, H.4
Matsuura, Y.5
Kaibuchi, K.6
-
34
-
-
0033578730
-
Protein phosphatase 2C inactivates F-actin binding of human platelet moesin
-
Hishiya A, Ohnishi M, Tamura S, Nakamura F. Protein phosphatase 2C inactivates F-actin binding of human platelet moesin. J Biol Chem 1999;274:26705-26712.
-
(1999)
J Biol Chem
, vol.274
, pp. 26705-26712
-
-
Hishiya, A.1
Ohnishi, M.2
Tamura, S.3
Nakamura, F.4
-
35
-
-
63349090552
-
Phospholipase C-mediated hydrolysis of PIP2 releases ERM proteins from lymphocyte membrane
-
Hao JJ, Liu Y, Kruhlak M, Debell KE, Rellahan BL, Shaw S. Phospholipase C-mediated hydrolysis of PIP2 releases ERM proteins from lymphocyte membrane. J Cell Biol 2009;184:451-462.
-
(2009)
J Cell Biol
, vol.184
, pp. 451-462
-
-
Hao, J.J.1
Liu, Y.2
Kruhlak, M.3
Debell, K.E.4
Rellahan, B.L.5
Shaw, S.6
-
36
-
-
0026760578
-
Identification of the two major epidermal growth factor-induced tyrosine phosphorylation sites in the microvillar core protein ezrin
-
Krieg J, Hunter T. Identification of the two major epidermal growth factor-induced tyrosine phosphorylation sites in the microvillar core protein ezrin. J Biol Chem 1992;267:19258-19265.
-
(1992)
J Biol Chem
, vol.267
, pp. 19258-19265
-
-
Krieg, J.1
Hunter, T.2
-
37
-
-
14844299368
-
Src-dependent ezrin phosphorylation in adhesion-mediated signaling
-
Srivastava J, Elliott BE, Louvard D, Arpin M. Src-dependent ezrin phosphorylation in adhesion-mediated signaling. Mol Biol Cell 2005;16:1481-1490.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 1481-1490
-
-
Srivastava, J.1
Elliott, B.E.2
Louvard, D.3
Arpin, M.4
-
38
-
-
0037472801
-
Ezrin is a substrate for Lck in T cells
-
Autero M, Heiska L, Ronnstrand L, Vaheri A, Gahmberg CG, Carpen O. Ezrin is a substrate for Lck in T cells. FEBS Lett 2003;535:82-86.
-
(2003)
FEBS Lett
, vol.535
, pp. 82-86
-
-
Autero, M.1
Heiska, L.2
Ronnstrand, L.3
Vaheri, A.4
Gahmberg, C.G.5
Carpen, O.6
-
39
-
-
0033594950
-
Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway
-
Gautreau A, Poullet P, Louvard D, Arpin M. Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway. Proc Natl Acad Sci USA 1999;96:7300-7305.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7300-7305
-
-
Gautreau, A.1
Poullet, P.2
Louvard, D.3
Arpin, M.4
-
40
-
-
15444367539
-
Src phosphorylates ezrin at tyrosine 477 and induces a phosphospecific association between ezrin and a kelch-repeat protein family member
-
Heiska L, Carpen O. Src phosphorylates ezrin at tyrosine 477 and induces a phosphospecific association between ezrin and a kelch-repeat protein family member. J Biol Chem 2005;280:10244-10252.
-
(2005)
J Biol Chem
, vol.280
, pp. 10244-10252
-
-
Heiska, L.1
Carpen, O.2
-
41
-
-
0042316854
-
Characterization of protein kinase A-mediated phosphorylation of ezrin in gastric parietal cell activation
-
Zhou R, et al. Characterization of protein kinase A-mediated phosphorylation of ezrin in gastric parietal cell activation. J Biol Chem 2003;278:35651-35659.
-
(2003)
J Biol Chem
, vol.278
, pp. 35651-35659
-
-
Zhou, R.1
-
42
-
-
0031471375
-
Ezrin: a protein requiring conformational activation to link microfilaments to the plasma membrane in the assembly of cell surface structures
-
Bretscher A, Reczek D, Berryman M. Ezrin: a protein requiring conformational activation to link microfilaments to the plasma membrane in the assembly of cell surface structures. J Cell Sci 1997;110:3011-3018.
-
(1997)
J Cell Sci
, vol.110
, pp. 3011-3018
-
-
Bretscher, A.1
Reczek, D.2
Berryman, M.3
-
43
-
-
0034597013
-
CD95 (APO-1/Fas) linkage to the actin cytoskeleton through ezrin in human T lymphocytes: a novel regulatory mechanism of the CD95 apoptotic pathway
-
Parlato S, et al. CD95 (APO-1/Fas) linkage to the actin cytoskeleton through ezrin in human T lymphocytes: a novel regulatory mechanism of the CD95 apoptotic pathway. EMBO J 2000;19:5123-5134.
-
(2000)
EMBO J
, vol.19
, pp. 5123-5134
-
-
Parlato, S.1
-
44
-
-
0032559637
-
Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2
-
Yonemura S, Hirao M, Doi Y, Takahashi N, Kondo T, Tsukita S. Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2. J Cell Biol 1998;140:885-895.
-
(1998)
J Cell Biol
, vol.140
, pp. 885-895
-
-
Yonemura, S.1
Hirao, M.2
Doi, Y.3
Takahashi, N.4
Kondo, T.5
Tsukita, S.6
-
45
-
-
0037127291
-
The cytoplasmic tail of L-selectin interacts with members of the Ezrin-Radixin-Moesin (ERM) family of proteins: cell activation-dependent binding of Moesin but not Ezrin
-
Ivetic A, Deka J, Ridley A, Ager A. The cytoplasmic tail of L-selectin interacts with members of the Ezrin-Radixin-Moesin (ERM) family of proteins: cell activation-dependent binding of Moesin but not Ezrin. J Biol Chem 2002;277:2321-2329.
-
(2002)
J Biol Chem
, vol.277
, pp. 2321-2329
-
-
Ivetic, A.1
Deka, J.2
Ridley, A.3
Ager, A.4
-
46
-
-
0036080407
-
A juxta-membrane amino acid sequence of P-selectin glycoprotein ligand-1 is involved in moesin binding and ezrin/radixin/moesin-directed targeting at the trailing edge of migrating lymphocytes
-
Serrador JM, et al. A juxta-membrane amino acid sequence of P-selectin glycoprotein ligand-1 is involved in moesin binding and ezrin/radixin/moesin-directed targeting at the trailing edge of migrating lymphocytes. Eur J Immunol 2002;32:1560-1566.
-
(2002)
Eur J Immunol
, vol.32
, pp. 1560-1566
-
-
Serrador, J.M.1
-
47
-
-
0037080345
-
Cutting edge: negative regulation of immune synapse formation by anchoring lipid raft to cytoskeleton through Cbp-EBP50-ERM assembly
-
Itoh K, et al. Cutting edge: negative regulation of immune synapse formation by anchoring lipid raft to cytoskeleton through Cbp-EBP50-ERM assembly. J Immunol 2002;168:541-544.
-
(2002)
J Immunol
, vol.168
, pp. 541-544
-
-
Itoh, K.1
-
48
-
-
80052461316
-
Proteomics analysis of the ezrin interactome in B cells reveals a novel association with Myo18aalpha
-
Matsui K, Parameswaran N, Bagheri N, Willard B, Gupta N. Proteomics analysis of the ezrin interactome in B cells reveals a novel association with Myo18aalpha. J Proteome Res 2011;10:3983-3992.
-
(2011)
J Proteome Res
, vol.10
, pp. 3983-3992
-
-
Matsui, K.1
Parameswaran, N.2
Bagheri, N.3
Willard, B.4
Gupta, N.5
-
49
-
-
0346997045
-
The fence and picket structure of the plasma membrane of live cells as revealed by single molecule techniques (Review)
-
Ritchie K, Iino R, Fujiwara T, Murase K, Kusumi A. The fence and picket structure of the plasma membrane of live cells as revealed by single molecule techniques (Review). Mol Membr Biol 2003;20:13-18.
-
(2003)
Mol Membr Biol
, vol.20
, pp. 13-18
-
-
Ritchie, K.1
Iino, R.2
Fujiwara, T.3
Murase, K.4
Kusumi, A.5
-
50
-
-
76949108167
-
The membrane skeleton controls diffusion dynamics and signaling through the B cell receptor
-
Treanor B, et al. The membrane skeleton controls diffusion dynamics and signaling through the B cell receptor. Immunity 2010;32:187-199.
-
(2010)
Immunity
, vol.32
, pp. 187-199
-
-
Treanor, B.1
-
51
-
-
66149112125
-
Early events of B cell activation by antigen
-
Depoil D, et al. Early events of B cell activation by antigen. Sci Signal 2009;2:pt1.
-
(2009)
Sci Signal
, vol.2
-
-
Depoil, D.1
-
52
-
-
70350354671
-
The molecular assembly and organization of signaling active B-cell receptor oligomers
-
Tolar P, Sohn HW, Liu W, Pierce SK. The molecular assembly and organization of signaling active B-cell receptor oligomers. Immunol Rev 2009;232:34-41.
-
(2009)
Immunol Rev
, vol.232
, pp. 34-41
-
-
Tolar, P.1
Sohn, H.W.2
Liu, W.3
Pierce, S.K.4
-
53
-
-
79956106702
-
Dynamic cortical actin remodeling by ERM proteins controls BCR microcluster organization and integrity
-
Treanor B, Depoil D, Bruckbauer A, Batista FD. Dynamic cortical actin remodeling by ERM proteins controls BCR microcluster organization and integrity. J Exp Med 2011;208:1055-1068.
-
(2011)
J Exp Med
, vol.208
, pp. 1055-1068
-
-
Treanor, B.1
Depoil, D.2
Bruckbauer, A.3
Batista, F.D.4
-
54
-
-
70350353059
-
Engagement of CD81 induces ezrin tyrosine phosphorylation and its cellular redistribution with filamentous actin
-
Coffey GP, et al. Engagement of CD81 induces ezrin tyrosine phosphorylation and its cellular redistribution with filamentous actin. J Cell Sci 2009;122:3137-3144.
-
(2009)
J Cell Sci
, vol.122
, pp. 3137-3144
-
-
Coffey, G.P.1
-
55
-
-
18644377589
-
ITAM-based interaction of ERM proteins with Syk mediates signaling by the leukocyte adhesion receptor PSGL-1
-
Urzainqui A, et al. ITAM-based interaction of ERM proteins with Syk mediates signaling by the leukocyte adhesion receptor PSGL-1. Immunity 2002;17:401-412.
-
(2002)
Immunity
, vol.17
, pp. 401-412
-
-
Urzainqui, A.1
-
56
-
-
60549109319
-
Ezrin and moesin function together to promote T cell activation
-
Shaffer MH, et al. Ezrin and moesin function together to promote T cell activation. J Immunol 2009;182:1021-1032.
-
(2009)
J Immunol
, vol.182
, pp. 1021-1032
-
-
Shaffer, M.H.1
-
57
-
-
0037008853
-
Clustering of a lipid-raft associated pool of ERM proteins at the immunological synapse upon T cell receptor or CD28 ligation
-
Tomas EM, Chau TA, Madrenas J. Clustering of a lipid-raft associated pool of ERM proteins at the immunological synapse upon T cell receptor or CD28 ligation. Immunol Lett 2002;83:143-147.
-
(2002)
Immunol Lett
, vol.83
, pp. 143-147
-
-
Tomas, E.M.1
Chau, T.A.2
Madrenas, J.3
-
58
-
-
36349036612
-
Immune synapse formation requires ZAP-70 recruitment by ezrin and CD43 removal by moesin
-
Ilani T, Khanna C, Zhou M, Veenstra TD, Bretscher A. Immune synapse formation requires ZAP-70 recruitment by ezrin and CD43 removal by moesin. J Cell Biol 2007;179:733-746.
-
(2007)
J Cell Biol
, vol.179
, pp. 733-746
-
-
Ilani, T.1
Khanna, C.2
Zhou, M.3
Veenstra, T.D.4
Bretscher, A.5
-
59
-
-
0035654721
-
The membrane-microfilament linker ezrin is involved in the formation of the immunological synapse and in T cell activation
-
Roumier A, et al. The membrane-microfilament linker ezrin is involved in the formation of the immunological synapse and in T cell activation. Immunity 2001;15:715-728.
-
(2001)
Immunity
, vol.15
, pp. 715-728
-
-
Roumier, A.1
-
60
-
-
77954886643
-
Ezrin tunes T-cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse
-
Lasserre R, et al. Ezrin tunes T-cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse. EMBO J 2010;29:2301-2314.
-
(2010)
EMBO J
, vol.29
, pp. 2301-2314
-
-
Lasserre, R.1
-
61
-
-
0026697728
-
Identification of ezrin as an 81-kDa tyrosine-phosphorylated protein in T cells
-
Egerton M, Burgess WH, Chen D, Druker BJ, Bretscher A, Samelson LE. Identification of ezrin as an 81-kDa tyrosine-phosphorylated protein in T cells. J Immunol 1992;149:1847-1852.
-
(1992)
J Immunol
, vol.149
, pp. 1847-1852
-
-
Egerton, M.1
Burgess, W.H.2
Chen, D.3
Druker, B.J.4
Bretscher, A.5
Samelson, L.E.6
-
63
-
-
0028141777
-
Ligation of CD4 surface antigen induces rapid tyrosine phosphorylation of the cytoskeletal protein ezrin
-
Thuillier L, Hivroz C, Fagard R, Andreoli C, Mangeat P. Ligation of CD4 surface antigen induces rapid tyrosine phosphorylation of the cytoskeletal protein ezrin. Cell Immunol 1994;156:322-331.
-
(1994)
Cell Immunol
, vol.156
, pp. 322-331
-
-
Thuillier, L.1
Hivroz, C.2
Fagard, R.3
Andreoli, C.4
Mangeat, P.5
-
64
-
-
0027183643
-
Ezrin is concentrated in the apical microvilli of a wide variety of epithelial cells whereas moesin is found primarily in endothelial cells
-
Berryman M, Franck Z, Bretscher A. Ezrin is concentrated in the apical microvilli of a wide variety of epithelial cells whereas moesin is found primarily in endothelial cells. J Cell Sci 1993;105:1025-1043.
-
(1993)
J Cell Sci
, vol.105
, pp. 1025-1043
-
-
Berryman, M.1
Franck, Z.2
Bretscher, A.3
-
65
-
-
51649124968
-
Enrichment of distinct microfilament-associated and GTP-binding-proteins in membrane/microvilli fractions from lymphoid cells
-
Hao JJ, et al. Enrichment of distinct microfilament-associated and GTP-binding-proteins in membrane/microvilli fractions from lymphoid cells. J Proteome Res 2008;7:2911-2927.
-
(2008)
J Proteome Res
, vol.7
, pp. 2911-2927
-
-
Hao, J.J.1
-
66
-
-
84882844733
-
Ezrin/Radixin/Moesin proteins and flotillins cooperate to promote uropod formation in T cells
-
Martinelli S, et al. Ezrin/Radixin/Moesin proteins and flotillins cooperate to promote uropod formation in T cells. Front Immunol 2013;4:84.
-
(2013)
Front Immunol
, vol.4
, pp. 84
-
-
Martinelli, S.1
-
67
-
-
84862940918
-
Constitutively active ezrin increases membrane tension, slows migration, and impedes endothelial transmigration of lymphocytes in vivo in mice
-
Liu Y, et al. Constitutively active ezrin increases membrane tension, slows migration, and impedes endothelial transmigration of lymphocytes in vivo in mice. Blood 2011;119:445-453.
-
(2011)
Blood
, vol.119
, pp. 445-453
-
-
Liu, Y.1
-
68
-
-
0031838741
-
CD43 interacts with moesin and ezrin and regulates its redistribution to the uropods of T lymphocytes at the cell-cell contacts
-
Serrador JM, et al. CD43 interacts with moesin and ezrin and regulates its redistribution to the uropods of T lymphocytes at the cell-cell contacts. Blood 1998;91:4632-4644.
-
(1998)
Blood
, vol.91
, pp. 4632-4644
-
-
Serrador, J.M.1
-
69
-
-
7244247060
-
Roles of p-ERM and Rho-ROCK signaling in lymphocyte polarity and uropod formation
-
Lee JH, Katakai T, Hara T, Gonda H, Sugai M, Shimizu A. Roles of p-ERM and Rho-ROCK signaling in lymphocyte polarity and uropod formation. J Cell Biol 2004;167:327-337.
-
(2004)
J Cell Biol
, vol.167
, pp. 327-337
-
-
Lee, J.H.1
Katakai, T.2
Hara, T.3
Gonda, H.4
Sugai, M.5
Shimizu, A.6
-
70
-
-
0032700438
-
Rho GTPases control migration and polarization of adhesion molecules and cytoskeletal ERM components in T lymphocytes
-
del Pozo MA, Vicente-Manzanares M, Tejedor R, Serrador JM, Sanchez-Madrid F. Rho GTPases control migration and polarization of adhesion molecules and cytoskeletal ERM components in T lymphocytes. Eur J Immunol 1999;29:3609-3620.
-
(1999)
Eur J Immunol
, vol.29
, pp. 3609-3620
-
-
del Pozo, M.A.1
Vicente-Manzanares, M.2
Tejedor, R.3
Serrador, J.M.4
Sanchez-Madrid, F.5
-
71
-
-
0030939803
-
ICAMs redistributed by chemokines to cellular uropods as a mechanism for recruitment of T lymphocytes
-
del Pozo MA, Cabanas C, Montoya MC, Ager A, Sanchez-Mateos P, Sanchez-Madrid F. ICAMs redistributed by chemokines to cellular uropods as a mechanism for recruitment of T lymphocytes. J Cell Biol 1997;137:493-508.
-
(1997)
J Cell Biol
, vol.137
, pp. 493-508
-
-
del Pozo, M.A.1
Cabanas, C.2
Montoya, M.C.3
Ager, A.4
Sanchez-Mateos, P.5
Sanchez-Madrid, F.6
-
72
-
-
34547760739
-
Activated ezrin promotes cell migration through recruitment of the GEF Dbl to lipid rafts and preferential downstream activation of Cdc42
-
Prag S, et al. Activated ezrin promotes cell migration through recruitment of the GEF Dbl to lipid rafts and preferential downstream activation of Cdc42. Mol Biol Cell 2007;18:2935-2948.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 2935-2948
-
-
Prag, S.1
-
73
-
-
38449083181
-
Age-related defects in moesin/ezrin cytoskeletal signals in mouse CD4 T cells
-
Garcia GG, Sadighi Akha AA, Miller RA. Age-related defects in moesin/ezrin cytoskeletal signals in mouse CD4 T cells. J Immunol 2007;179:6403-6409.
-
(2007)
J Immunol
, vol.179
, pp. 6403-6409
-
-
Garcia, G.G.1
Sadighi Akha, A.A.2
Miller, R.A.3
-
74
-
-
2942622503
-
Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine
-
Saotome I, Curto M, McClatchey AI. Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine. Dev Cell 2004;6:855-864.
-
(2004)
Dev Cell
, vol.6
, pp. 855-864
-
-
Saotome, I.1
Curto, M.2
McClatchey, A.I.3
-
75
-
-
31044441357
-
Microvilli defects in retinas of ezrin knockout mice
-
Bonilha VL, Rayborn ME, Saotome I, McClatchey AI, Hollyfield JG. Microvilli defects in retinas of ezrin knockout mice. Exp Eye Res 2006;82:720-729.
-
(2006)
Exp Eye Res
, vol.82
, pp. 720-729
-
-
Bonilha, V.L.1
Rayborn, M.E.2
Saotome, I.3
McClatchey, A.I.4
Hollyfield, J.G.5
-
76
-
-
20244363654
-
Achlorhydria by ezrin knockdown: defects in the formation/expansion of apical canaliculi in gastric parietal cells
-
Tamura A, et al. Achlorhydria by ezrin knockdown: defects in the formation/expansion of apical canaliculi in gastric parietal cells. J Cell Biol 2005;169:21-28.
-
(2005)
J Cell Biol
, vol.169
, pp. 21-28
-
-
Tamura, A.1
-
77
-
-
4143152925
-
Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia
-
Kitajiri S, et al. Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia. J Cell Biol 2004;166:559-570.
-
(2004)
J Cell Biol
, vol.166
, pp. 559-570
-
-
Kitajiri, S.1
-
78
-
-
0036648878
-
Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes
-
Kikuchi S, et al. Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes. Nat Genet 2002;31:320-325.
-
(2002)
Nat Genet
, vol.31
, pp. 320-325
-
-
Kikuchi, S.1
-
79
-
-
0033593481
-
Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout
-
Doi Y, et al. Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout. J Biol Chem 1999;274:2315-2321.
-
(1999)
J Biol Chem
, vol.274
, pp. 2315-2321
-
-
Doi, Y.1
-
80
-
-
49549092936
-
Attenuated response to liver injury in moesin-deficient mice: impaired stellate cell migration and decreased fibrosis
-
Okayama T, et al. Attenuated response to liver injury in moesin-deficient mice: impaired stellate cell migration and decreased fibrosis. Biochim Biophys Acta 2008;1782:542-548.
-
(2008)
Biochim Biophys Acta
, vol.1782
, pp. 542-548
-
-
Okayama, T.1
-
81
-
-
56149095752
-
Dysregulation of lung injury and repair in moesin-deficient mice treated with intratracheal bleomycin
-
Hashimoto S, et al. Dysregulation of lung injury and repair in moesin-deficient mice treated with intratracheal bleomycin. Am J Physiol Lung Cell Mol Physiol 2008;295:L566-L574.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.295
-
-
Hashimoto, S.1
-
82
-
-
84874536522
-
Ezrin and moesin are required for efficient T cell adhesion and homing to lymphoid organs
-
Chen EJ, Shaffer MH, Williamson EK, Huang Y, Burkhardt JK. Ezrin and moesin are required for efficient T cell adhesion and homing to lymphoid organs. PLoS ONE 2013;8:e52368.
-
(2013)
PLoS ONE
, vol.8
-
-
Chen, E.J.1
Shaffer, M.H.2
Williamson, E.K.3
Huang, Y.4
Burkhardt, J.K.5
-
83
-
-
77957914392
-
Ezrin is highly expressed in early thymocytes, but dispensable for T cell development in mice
-
Shaffer MH, et al. Ezrin is highly expressed in early thymocytes, but dispensable for T cell development in mice. PLoS ONE 2010;5:e12404.
-
(2010)
PLoS ONE
, vol.5
-
-
Shaffer, M.H.1
-
84
-
-
84868123643
-
Moesin-deficient mice reveal a non-redundant role for moesin in lymphocyte homeostasis
-
Hirata T, et al. Moesin-deficient mice reveal a non-redundant role for moesin in lymphocyte homeostasis. Int Immunol 2012;24:705-717.
-
(2012)
Int Immunol
, vol.24
, pp. 705-717
-
-
Hirata, T.1
-
85
-
-
62149083847
-
Moesin is required for HIV-1-induced CD4-CXCR4 interaction, F-actin redistribution, membrane fusion and viral infection in lymphocytes
-
Barrero-Villar M, et al. Moesin is required for HIV-1-induced CD4-CXCR4 interaction, F-actin redistribution, membrane fusion and viral infection in lymphocytes. J Cell Sci 2009;122:103-113.
-
(2009)
J Cell Sci
, vol.122
, pp. 103-113
-
-
Barrero-Villar, M.1
-
86
-
-
2342557375
-
CD95/phosphorylated ezrin association underlies HIV-1 GP120/IL-2-induced susceptibility to CD95(APO-1/Fas)-mediated apoptosis of human resting CD4(+)T lymphocytes
-
Luciani F, et al. CD95/phosphorylated ezrin association underlies HIV-1 GP120/IL-2-induced susceptibility to CD95(APO-1/Fas)-mediated apoptosis of human resting CD4(+)T lymphocytes. Cell Death Differ 2004;11:574-582.
-
(2004)
Cell Death Differ
, vol.11
, pp. 574-582
-
-
Luciani, F.1
-
87
-
-
79957785375
-
PDZD8 is a novel moesin-interacting cytoskeletal regulatory protein that suppresses infection by herpes simplex virus type 1
-
Henning MS, et al. PDZD8 is a novel moesin-interacting cytoskeletal regulatory protein that suppresses infection by herpes simplex virus type 1. Virology 2011;415:114-121.
-
(2011)
Virology
, vol.415
, pp. 114-121
-
-
Henning, M.S.1
-
88
-
-
0345691365
-
A functional role for ezrin during Shigella flexneri entry into epithelial cells
-
Skoudy A, et al. A functional role for ezrin during Shigella flexneri entry into epithelial cells. J Cell Sci 1999;112:2059-2068.
-
(1999)
J Cell Sci
, vol.112
, pp. 2059-2068
-
-
Skoudy, A.1
-
89
-
-
17144399487
-
Listeria monocytogenes exploits ERM protein functions to efficiently spread from cell to cell
-
Pust S, Morrison H, Wehland J, Sechi AS, Herrlich P. Listeria monocytogenes exploits ERM protein functions to efficiently spread from cell to cell. EMBO J 2005;24:1287-1300.
-
(2005)
EMBO J
, vol.24
, pp. 1287-1300
-
-
Pust, S.1
Morrison, H.2
Wehland, J.3
Sechi, A.S.4
Herrlich, P.5
-
90
-
-
79954572864
-
Knockdown of ezrin via RNA interference suppresses Helicobacter pylori-enhanced invasion of gastric cancer cells
-
Fan LL, Chen DF, Lan CH, Liu KY, Fang DC. Knockdown of ezrin via RNA interference suppresses Helicobacter pylori-enhanced invasion of gastric cancer cells. Cancer Biol Ther 2011;11:746-752.
-
(2011)
Cancer Biol Ther
, vol.11
, pp. 746-752
-
-
Fan, L.L.1
Chen, D.F.2
Lan, C.H.3
Liu, K.Y.4
Fang, D.C.5
-
91
-
-
81355154689
-
The ERM protein, ezrin, regulates neutrophil transmigration by modulating the apical localization of MRP2 in response to the SipA effector protein during Salmonella Typhimurium infection
-
Agbor TA, Demma ZC, Mumy KL, Bien JD, McCormick BA. The ERM protein, ezrin, regulates neutrophil transmigration by modulating the apical localization of MRP2 in response to the SipA effector protein during Salmonella Typhimurium infection. Cell Microbiol 2011;13:2007-2021.
-
(2011)
Cell Microbiol
, vol.13
, pp. 2007-2021
-
-
Agbor, T.A.1
Demma, Z.C.2
Mumy, K.L.3
Bien, J.D.4
McCormick, B.A.5
-
92
-
-
79955541351
-
Mice with disrupted type I protein kinase A anchoring in T cells resist retrovirus-induced immunodeficiency
-
Mosenden R, et al. Mice with disrupted type I protein kinase A anchoring in T cells resist retrovirus-induced immunodeficiency. J Immunol 2011;186:5119-5130.
-
(2011)
J Immunol
, vol.186
, pp. 5119-5130
-
-
Mosenden, R.1
-
93
-
-
34247603150
-
Expression of the cytoskeleton linker protein ezrin in human cancers
-
Bruce B, et al. Expression of the cytoskeleton linker protein ezrin in human cancers. Clin Exp Metastasis 2007;24:69-78.
-
(2007)
Clin Exp Metastasis
, vol.24
, pp. 69-78
-
-
Bruce, B.1
-
94
-
-
1442334887
-
Ezrin a metastatic detERMinant?
-
Curto M, McClatchey AI. Ezrin a metastatic detERMinant? Cancer Cell 2004;5:113-114.
-
(2004)
Cancer Cell
, vol.5
, pp. 113-114
-
-
Curto, M.1
McClatchey, A.I.2
-
95
-
-
77949423269
-
Ezrin mediates c-Myc actions in prostate cancer cell invasion
-
Chuan YC, et al. Ezrin mediates c-Myc actions in prostate cancer cell invasion. Oncogene 2009;29:1531-1542.
-
(2009)
Oncogene
, vol.29
, pp. 1531-1542
-
-
Chuan, Y.C.1
-
96
-
-
77952092336
-
Ezrin is a key molecule in the metastasis of MOLT4 cells induced by CCL25/CCR9
-
Zhou B, et al. Ezrin is a key molecule in the metastasis of MOLT4 cells induced by CCL25/CCR9. Leuk Res 2010;34:769-776.
-
(2010)
Leuk Res
, vol.34
, pp. 769-776
-
-
Zhou, B.1
-
97
-
-
84878298628
-
Ezrin dephosphorylation/downregulation contributes to ursolic acid-mediated cell death in human leukemia cells
-
Li G, et al. Ezrin dephosphorylation/downregulation contributes to ursolic acid-mediated cell death in human leukemia cells. Blood Cancer J 2013;3:e108.
-
(2013)
Blood Cancer J
, vol.3
-
-
Li, G.1
-
98
-
-
84878322681
-
Loss of TCR-beta F1 and/or EZRIN expression is associated with unfavorable prognosis in nodal peripheral T-cell lymphomas
-
Rodriguez-Pinilla SM, et al. Loss of TCR-beta F1 and/or EZRIN expression is associated with unfavorable prognosis in nodal peripheral T-cell lymphomas. Blood Cancer J 2013;3:e111.
-
(2013)
Blood Cancer J
, vol.3
-
-
Rodriguez-Pinilla, S.M.1
-
99
-
-
33846536952
-
Phosphorylated ERM is responsible for increased T cell polarization, adhesion, and migration in patients with systemic lupus erythematosus
-
Li Y, et al. Phosphorylated ERM is responsible for increased T cell polarization, adhesion, and migration in patients with systemic lupus erythematosus. J Immunol 2007;178:1938-1947.
-
(2007)
J Immunol
, vol.178
, pp. 1938-1947
-
-
Li, Y.1
-
100
-
-
0025769919
-
The secretion-stimulated 80K phosphoprotein of parietal cells is ezrin, and has properties of a membrane cytoskeletal linker in the induced apical microvilli
-
Hanzel D, Reggio H, Bretscher A, Forte JG, Mangeat P. The secretion-stimulated 80K phosphoprotein of parietal cells is ezrin, and has properties of a membrane cytoskeletal linker in the induced apical microvilli. EMBO J 1991;10:2363-2373.
-
(1991)
EMBO J
, vol.10
, pp. 2363-2373
-
-
Hanzel, D.1
Reggio, H.2
Bretscher, A.3
Forte, J.G.4
Mangeat, P.5
-
101
-
-
31744449520
-
PKA-mediated protein phosphorylation regulates ezrin-WWOX interaction
-
Jin C, et al. PKA-mediated protein phosphorylation regulates ezrin-WWOX interaction. Biochem Biophys Res Commun 2006;341:784-791.
-
(2006)
Biochem Biophys Res Commun
, vol.341
, pp. 784-791
-
-
Jin, C.1
-
102
-
-
0030847406
-
Moesin interacts with the cytoplasmic region of intercellular adhesion molecule-3 and is redistributed to the uropod of T lymphocytes during cell polarization
-
Serrador JM, et al. Moesin interacts with the cytoplasmic region of intercellular adhesion molecule-3 and is redistributed to the uropod of T lymphocytes during cell polarization. J Cell Biol 1997;138:1409-1423.
-
(1997)
J Cell Biol
, vol.138
, pp. 1409-1423
-
-
Serrador, J.M.1
-
103
-
-
18244364886
-
ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse
-
Allenspach EJ, et al. ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse. Immunity 2001;15:739-750.
-
(2001)
Immunity
, vol.15
, pp. 739-750
-
-
Allenspach, E.J.1
|