Propionyl-L-carnitine induces eNOS activation and nitric oxide synthesis in endothelial cells via PI3 and Akt kinases

Vascular Pharmacology

Volumn 59, Issue 3-4, 2013, Pages 76-82

  Ning, Wen hu ^a   Zhao, Kan ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Akt; Endothelial cells; Endothelial nitric oxide synthase; Phosphatidylinositol 3 kinase; Propionyl l carnitine

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; 6 (2,6 DICHLOROPHENYL) 8 METHYL 2 (3 METHYLTHIOANILINO) 8H PYRIDO[2,3 D]PYRIMIDIN 7 ONE; 8 [4 (1 AMINOCYCLOBUTYL)PHENYL] 9 PHENYL 1,2,4 TRIAZOLO[3,4 F][1,6]NAPHTHYRIDIN 3(2H) ONE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; N(G) NITROARGININE METHYL ESTER; PHOSPHATIDYLINOSITOL 3 KINASE; PROPIONYLCARNITINE; PROTEIN KINASE P60;

ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HEART PROTECTION; HUMAN; HUMAN CELL; MICROVASCULAR ENDOTHELIAL CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

(PLC); AKT; DN-AKT; DOMINANT-NEGATIVE MUTANT OF PROTEIN KINASE B (AKT); ENDOTHELIAL CELLS; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENOS; HAEC; HUMAN AORTIC ENDOTHELIAL CELLS; L-CARNITINE; LC; NITRIC OXIDE; NO; PHOSPHATIDYLINOSITOL 3-KINASE; PI3 KINASE; PROPIONYL-L-CARNITINE; SHR; SPONTANEOUSLY HYPERTENSIVE RATS;

AMP-ACTIVATED PROTEIN KINASES; AORTA; CARNITINE; CELLS, CULTURED; ENDOTHELIAL CELLS; HUMANS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 84885293932     PISSN: 15371891     EISSN: 18793649     Source Type: Journal    
DOI: 10.1016/j.vph.2013.07.001     Document Type: Article

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