Mechanistic basis of desmosome-targeted diseases

Journal of Molecular Biology

Volumn 425, Issue 21, 2013, Pages 4006-4022

  Al Jassar, Caezar ^a   Bikker, Hennie ^b   Overduin, Michael ^a   Chidgey, Martyn ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

arrhythmogenic right ventricular cardiomyopathy; desmoplakin; desmosomal cadherin; desmosome; plakoglobin

Indexed keywords

BETA CATENIN; CADHERIN; DESMIN; DESMOCOLLIN; DESMOCOLLIN 2; DESMOCOLLIN 3; DESMOGLEIN 2; DESMOPLAKIN; DESMOSOMAL CADHERIN; EPIDERMAL GROWTH FACTOR RECEPTOR; KERATIN; MUTANT PROTEIN; PLAKIN; PLAKOGLOBIN; PLAKOPHILIN; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN;

BINDING SITE; CANCER GROWTH; CELL MEMBRANE; CELL STRUCTURE; CRYOELECTRON MICROSCOPY; CRYSTAL STRUCTURE; DESMOSOMAL DISEASE; DESMOSOME; ELECTRON TOMOGRAPHY; GENE DELETION; GENE MUTATION; GENETIC DISORDER; HEART MUSCLE CELL; HEART RIGHT VENTRICLE DYSPLASIA; HUMAN; MECHANICAL STRESS; MISSENSE MUTATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OROPHARYNX TUMOR; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; RECEPTOR DOWN REGULATION; REVIEW; SIGNAL TRANSDUCTION; X RAY CRYSTALLOGRAPHY;

ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY; ARVC; DESMOPLAKIN; DESMOSOMAL CADHERIN; DESMOSOME; DESMOSOME-INTERMEDIATE FILAMENT COMPLEX; DIFC; EC; EGFR; EPIDERMAL GROWTH FACTOR RECEPTOR; EXTRACELLULAR CADHERIN; IA; ICS; INDUCED PLURIPOTENT STEM CELL; INTRACELLULAR ANCHOR; INTRACELLULAR CADHERIN-TYPICAL SEQUENCE; IPSC; LEF; LYMPHOID ENHANCER FACTOR; NMD; NONSENSE-MEDIATED RNA DECAY; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PLAKIN REPEAT DOMAIN; PLAKOGLOBIN; PPAR; PRD; SH3; SPECTRIN REPEAT; SR; SRC HOMOLOGY 3; T-CELL FACTOR; TCF;

ANIMALS; DESMOPLAKINS; DESMOSOMES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MUTATION; PLAKOPHILINS; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS;

EID: 84885190645     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2013.07.035     Document Type: Review

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