Molecular changes in the heart of a severe case of arrhythmogenic right ventricular cardiomyopathy caused by a desmoglein-2 null allele

Cardiovascular Pathology

Volumn 21, Issue 4, 2012, Pages 275-282

  Gehmlich, Katja ^a,e   Syrris, Petros ^a   Reimann, Mareike ^a   Asimaki, Angeliki ^b   Ehler, Elisabeth ^c   Evans, Alison ^a   Quarta, Giovanni ^a,d   Pantazis, Antonis ^a   Saffitz, Jeffrey E ^b   McKenna, William J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b HARVARD MEDICAL SCHOOL   (United States)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

^e UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Arrhythmogenic right ventricular cardiomyopathy; Cardiac transplant; Connexin43; Desmoglein 2; Desmosomal mutation; End stage heart failure; Gap junction; Plakoglobin

Indexed keywords

COMPLEMENTARY DNA; CONNEXIN 43; DESMOCOLLIN; DESMOGLEIN 2; NERVE CELL ADHESION MOLECULE; PLAKOGLOBIN; PLAKOPHILIN;

ARTICLE; CELL JUNCTION; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; GENE EXPRESSION; GENE MUTATION; HEART FAILURE; HEART REPOLARIZATION; HEART RIGHT VENTRICLE DYSPLASIA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NULL ALLELE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; Q WAVE; T WAVE; WESTERN BLOTTING;

ADOLESCENT; ANIMALS; ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA; BLOTTING, WESTERN; CERCOPITHECUS AETHIOPS; CONNEXIN 43; COS CELLS; DESMOGLEIN 2; GAMMA CATENIN; GENE SILENCING; HEART FAILURE; HEART TRANSPLANTATION; HEART VENTRICLES; HETEROZYGOTE; HUMANS; MALE; MYOCARDIUM; PHOSPHORYLATION; TRANSFECTION;

EID: 84863717016     PISSN: 10548807     EISSN: 18791336     Source Type: Journal    
DOI: 10.1016/j.carpath.2011.09.005     Document Type: Article

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