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Volumn 137, Issue 10, 2013, Pages 1326-1336

Enhancer of zeste homolog 2 expression is associated with metastasis and adverse clinical outcome in clear cell renal cell carcinoma: A comparative study and review of the literature

Author keywords

[No Author keywords available]

Indexed keywords

EZH2 PROTEIN, HUMAN; POLYCOMB REPRESSIVE COMPLEX 2; TUMOR MARKER;

EID: 84885164072     PISSN: 00039985     EISSN: 15432165     Source Type: Journal    
DOI: 10.5858/arpa.2012-0525-OA     Document Type: Article
Times cited : (19)

References (98)
  • 1
    • 84867400172 scopus 로고    scopus 로고
    • Epigenomics of cancer-emerging new concepts
    • Hassler MR, Egger G. Epigenomics of cancer-emerging new concepts. Biochimie. 2012;94(11):2219-2230.
    • (2012) Biochimie. , vol.94 , Issue.11 , pp. 2219-2230
    • Hassler, M.R.1    Egger, G.2
  • 2
    • 84860635387 scopus 로고    scopus 로고
    • Epigenetics: Marked for success
    • Ledford H. Epigenetics: marked for success. Nature. 2012;483(7391):637- 639.
    • (2012) Nature. , vol.483 , Issue.7391 , pp. 637-639
    • Ledford, H.1
  • 3
    • 84873084354 scopus 로고    scopus 로고
    • Genomics and Epigenomics of Renal Cell Carcinoma [Published Online Ahead of Print June 28, 2012]
    • doi: 10.1016/j.semcancer.2012.06.003-rfsti Semin Cancer Biol
    • Maher ER. Genomics and epigenomics of renal cell carcinoma [published online ahead of print June 28, 2012]. doi: 10.1016/j.semcancer.2012.06.003 Semin Cancer Biol.
    • Semin Cancer Biol
    • Maher, E.R.1
  • 4
    • 84858439628 scopus 로고    scopus 로고
    • Cancer epigenomics: Beyond genomics
    • Sandoval J, Esteller M. Cancer epigenomics: beyond genomics. Curr Opin Genet Dev. 2012;22(1):50-55.
    • (2012) Curr Opin Genet Dev. , vol.22 , Issue.1 , pp. 50-55
    • Sandoval, J.1    Esteller, M.2
  • 5
    • 84861169885 scopus 로고    scopus 로고
    • Epigenetic therapy in cancer: Perspective and paradoxes
    • Filosa A, Fabiani A. Epigenetic therapy in cancer: perspective and paradoxes. Anal Quant Cytol Histol. 2011;33(5):303-304.
    • (2011) Anal Quant Cytol Histol. , vol.33 , Issue.5 , pp. 303-304
    • Filosa, A.1    Fabiani, A.2
  • 6
    • 84908130650 scopus 로고    scopus 로고
    • Research highlights: Significance of epigenetic modifiers in cancer progression: Potential for therapy
    • Jazirehi AR, Arle D, Wenn PB. Research highlights: significance of epigenetic modifiers in cancer progression: potential for therapy. Epigenomics. 2012;4(3):251-254.
    • (2012) Epigenomics. , vol.4 , Issue.3 , pp. 251-254
    • Jazirehi, A.R.1    Arle, D.2    Wenn, P.B.3
  • 8
    • 55949136562 scopus 로고    scopus 로고
    • Roles of the EZH2 histone methyltransferase in cancer epigenetics
    • Simon JA, Lange CA. Roles of the EZH2 histone methyltransferase in cancer epigenetics. Mutat Res. 2008;647(1-2):21-29.
    • (2008) Mutat Res. , vol.647 , Issue.2 , pp. 21-29
    • Simon, J.A.1    Lange, C.A.2
  • 9
    • 78650412626 scopus 로고    scopus 로고
    • Epigenetic regulation of signaling pathways in cancer: Role of the histone methyltransferase EZH2
    • Tsang DP, Cheng AS. Epigenetic regulation of signaling pathways in cancer: role of the histone methyltransferase EZH2. J Gastroenterol Hepatol. 2011;26(1):19-27.
    • (2011) J Gastroenterol Hepatol. , vol.26 , Issue.1 , pp. 19-27
    • Tsang, D.P.1    Cheng, A.S.2
  • 10
    • 79952105934 scopus 로고    scopus 로고
    • Enhancer of zeste homolog 2: A potential target for tumor therapy
    • Xiao Y. Enhancer of zeste homolog 2: a potential target for tumor therapy. Int J Biochem Cell Biol. 2011;43(4):474-477.
    • (2011) Int J Biochem Cell Biol. , vol.43 , Issue.4 , pp. 474-477
    • Xiao, Y.1
  • 11
    • 84864344679 scopus 로고    scopus 로고
    • Enhancer of zeste homolog 2 epigenetically silences multiple tumor suppressor microRNAs to promote liver cancer metastasis
    • Au SL, Wong CC, Lee JM, et al. Enhancer of zeste homolog 2 epigenetically silences multiple tumor suppressor microRNAs to promote liver cancer metastasis. Hepatology. 2012;56(2):622-631.
    • (2012) Hepatology. , vol.56 , Issue.2 , pp. 622-631
    • Au, S.L.1    Wong, C.C.2    Lee, J.M.3
  • 12
    • 79959794787 scopus 로고    scopus 로고
    • Clinical effect of point mutations in myelodysplastic syndromes
    • Bejar R, Stevenson K, Abdel-Wahab O, et al. Clinical effect of point mutations in myelodysplastic syndromes. N Engl J Med. 2011;364(26):2496-2506.
    • (2011) N Engl J Med. , vol.364 , Issue.26 , pp. 2496-2506
    • Bejar, R.1    Stevenson, K.2    Abdel-Wahab, O.3
  • 13
    • 67650511419 scopus 로고    scopus 로고
    • Epigenetic maintenance of stemness and malignancy in peripheral neuroectodermal tumors by EZH2
    • Burdach S, Plehm S, Unland R, et al. Epigenetic maintenance of stemness and malignancy in peripheral neuroectodermal tumors by EZH2. Cell Cycle. 2009;8(13):1991-1996.
    • (2009) Cell Cycle. , vol.8 , Issue.13 , pp. 1991-1996
    • Burdach, S.1    Plehm, S.2    Unland, R.3
  • 14
    • 57649124289 scopus 로고    scopus 로고
    • Repression of E-cadherin by the polycomb group protein EZH2 in cancer
    • Cao Q, Yu J, Dhanasekaran SM, et al. Repression of E-cadherin by the polycomb group protein EZH2 in cancer. Oncogene. 2008;27(58):7274-7284.
    • (2008) Oncogene. , vol.27 , Issue.58 , pp. 7274-7284
    • Cao, Q.1    Yu, J.2    Dhanasekaran, S.M.3
  • 15
    • 18644382388 scopus 로고    scopus 로고
    • The polycomb group protein EZH2 is involved in progression of prostate cancer
    • Varambally S, Dhanasekaran SM, Zhou M, et al. The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature. 2002; 419(6907):624-629.
    • (2002) Nature. , vol.419 , Issue.6907 , pp. 624-629
    • Varambally, S.1    Dhanasekaran, S.M.2    Zhou, M.3
  • 17
    • 79958219307 scopus 로고    scopus 로고
    • EZH2 protein: A promising immunomarker for the detection of hepatocellular carcinomas in liver needle biopsies
    • Cai MY, Tong ZT, Zheng F, et al. EZH2 protein: a promising immunomarker for the detection of hepatocellular carcinomas in liver needle biopsies. Gut. 2011;60(7):967-976.
    • (2011) Gut. , vol.60 , Issue.7 , pp. 967-976
    • Cai, M.Y.1    Tong, Z.T.2    Zheng, F.3
  • 18
    • 34250793839 scopus 로고    scopus 로고
    • EZH2 polycomb transcriptional repressor expression correlates with methylation of the APAF-1 gene in superficial transitional cell carcinoma of the bladder
    • DOI 10.1159/000103380
    • Hinz S, Kempkensteffen C, Weikert S, et al. EZH2 polycomb transcriptional repressor expression correlates with methylation of the APAF-1 gene in superficial transitional cell carcinoma of the bladder. Tumour Biol. 2007;28(3):151-157. (Pubitemid 46976001)
    • (2007) Tumor Biology , vol.28 , Issue.3 , pp. 151-157
    • Hinz, S.1    Kempkensteffen, C.2    Weikert, S.3    Schostak, M.4    Schrader, M.5    Miller, K.6    Christoph, F.7
  • 20
    • 33748371194 scopus 로고    scopus 로고
    • Epigenetics of prostate cancer: Beyond DNA methylation
    • DOI 10.1111/j.1582-4934.2006.tb00293.x
    • Schulz WA, Hatina J. Epigenetics of prostate cancer: beyond DNA methylation. J Cell Mol Med. 2006;10(1):100-125. (Pubitemid 44874294)
    • (2006) Journal of Cellular and Molecular Medicine , vol.10 , Issue.1 , pp. 100-125
    • Schulz, W.A.1    Hatina, J.2
  • 21
    • 84862983558 scopus 로고    scopus 로고
    • Increased EZH2 protein expression is associated with invasive urothelial carcinoma of the bladder
    • Wang H, Albadine R, Magheli A, et al. Increased EZH2 protein expression is associated with invasive urothelial carcinoma of the bladder. Urol Oncol. 2012;30(4):428-433.
    • (2012) Urol Oncol. , vol.30 , Issue.4 , pp. 428-433
    • Wang, H.1    Albadine, R.2    Magheli, A.3
  • 22
    • 60749126576 scopus 로고    scopus 로고
    • Deregulated expression of miR-26a and Ezh2 in rhabdomyosarcoma
    • Ciarapica R, Russo G, Verginelli F, et al. Deregulated expression of miR-26a and Ezh2 in rhabdomyosarcoma. Cell Cycle. 2009;8(1):172-175.
    • (2009) Cell Cycle. , vol.8 , Issue.1 , pp. 172-175
    • Ciarapica, R.1    Russo, G.2    Verginelli, F.3
  • 23
    • 80955176375 scopus 로고    scopus 로고
    • Enhancer of zeste homolog 2 (EZH2) in pediatric soft tissue sarcomas: First implications
    • Ciarapica R, Miele L, Giordano A, Locatelli F, Rota R. Enhancer of zeste homolog 2 (EZH2) in pediatric soft tissue sarcomas: first implications. BMC Med. 2011;9:63.
    • (2011) BMC Med. , vol.9 , pp. 63
    • Ciarapica, R.1    Miele, L.2    Giordano, A.3    Locatelli, F.4    Rota, R.5
  • 24
    • 78651241548 scopus 로고    scopus 로고
    • Aberrant expression of EZH2 is associated with a poor outcome and P53 alteration in squamous cell carcinoma of the esophagus
    • Yamada A, Fujii S, Daiko H, Nishimura M, Chiba T, Ochiai A. Aberrant expression of EZH2 is associated with a poor outcome and P53 alteration in squamous cell carcinoma of the esophagus. Int J Oncol. 2011;38(2):345-353.
    • (2011) Int J Oncol. , vol.38 , Issue.2 , pp. 345-353
    • Yamada, A.1    Fujii, S.2    Daiko, H.3    Nishimura, M.4    Chiba, T.5    Ochiai, A.6
  • 26
    • 80053545678 scopus 로고    scopus 로고
    • Mutations in epigenetic modifiers in myeloid malignancies and the prospect of novel epigenetic-targeted therapy
    • Fathi AT, Abdel-Wahab O. Mutations in epigenetic modifiers in myeloid malignancies and the prospect of novel epigenetic-targeted therapy. Adv Hematol. 2012;2012:469592.
    • Adv Hematol. , vol.2012 , pp. 469592
    • Fathi, A.T.1    Abdel-Wahab, O.2
  • 27
    • 70350494322 scopus 로고    scopus 로고
    • Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells
    • Fiskus W, Wang Y, Sreekumar A, et al. Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells. Blood. 2009;114(13):2733-2743.
    • (2009) Blood. , vol.114 , Issue.13 , pp. 2733-2743
    • Fiskus, W.1    Wang, Y.2    Sreekumar, A.3
  • 28
    • 84856747744 scopus 로고    scopus 로고
    • Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia
    • Ntziachristos P, Tsirigos A, Van VP, et al. Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia. Nat Med. 2012;18(2):298-301.
    • (2012) Nat Med. , vol.18 , Issue.2 , pp. 298-301
    • Ntziachristos, P.1    Tsirigos, A.2    Van, V.P.3
  • 29
    • 79960891281 scopus 로고    scopus 로고
    • DNA methylation as a pathogenic event and as a therapeutic target in AML
    • Schoofs T, Muller-Tidow C. DNA methylation as a pathogenic event and as a therapeutic target in AML. Cancer Treat Rev. 2011;37(suppl 1):S13-S18.
    • (2011) Cancer Treat Rev. , vol.37 , Issue.SUPPL. 1
    • Schoofs, T.1    Muller-Tidow, C.2
  • 30
    • 79959590587 scopus 로고    scopus 로고
    • Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells
    • Xie Z, Bi C, Cheong LL, et al. Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells. PLoS One. 2011;6(6):e21583.
    • (2011) PLoS One. , vol.6 , Issue.6
    • Xie, Z.1    Bi, C.2    Cheong, L.L.3
  • 31
    • 77955085750 scopus 로고    scopus 로고
    • Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
    • Ernst T, Chase AJ, Score J, et al. Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders. Nat Genet. 2010;42(8):722-726.
    • (2010) Nat Genet. , vol.42 , Issue.8 , pp. 722-726
    • Ernst, T.1    Chase, A.J.2    Score, J.3
  • 32
    • 84856271833 scopus 로고    scopus 로고
    • Epigenetic abnormalities in myeloproliferative neoplasms: A target for novel therapeutic strategies
    • Mascarenhas J, Roper N, Chaurasia P, Hoffman R. Epigenetic abnormalities in myeloproliferative neoplasms: a target for novel therapeutic strategies. Clin Epigenetics. 2011;2(2):197-212.
    • (2011) Clin Epigenetics. , vol.2 , Issue.2 , pp. 197-212
    • Mascarenhas, J.1    Roper, N.2    Chaurasia, P.3    Hoffman, R.4
  • 33
    • 84859042371 scopus 로고    scopus 로고
    • Update on cytogenetic and molecular changes in myelodysplastic syndromes
    • Schlegelberger B, Gohring G, Thol F, Heuser M. Update on cytogenetic and molecular changes in myelodysplastic syndromes. Leuk Lymphoma. 2012; 53(4):525-536.
    • (2012) Leuk Lymphoma. , vol.53 , Issue.4 , pp. 525-536
    • Schlegelberger, B.1    Gohring, G.2    Thol, F.3    Heuser, M.4
  • 34
    • 84864100711 scopus 로고    scopus 로고
    • The role of histone methyltransferase EZH2 in myelodysplastic syndromes
    • Xu F, Li X. The role of histone methyltransferase EZH2 in myelodysplastic syndromes. Expert Rev Hematol. 2012;5(2):177-185.
    • (2012) Expert Rev Hematol. , vol.5 , Issue.2 , pp. 177-185
    • Xu, F.1    Li, X.2
  • 35
    • 79957552560 scopus 로고    scopus 로고
    • Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98
    • Alajez NM, Shi W, Hui AB, et al. Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98. Cell Death Dis. 2010;1:e85.
    • (2010) Cell Death Dis. , vol.1
    • Alajez, N.M.1    Shi, W.2    Hui, A.B.3
  • 36
    • 84859099474 scopus 로고    scopus 로고
    • Increased risk for distant metastasis in patients with familial early-stage breast cancer and high EZH2 expression
    • Alford SH, Toy K, Merajver SD, Kleer CG. Increased risk for distant metastasis in patients with familial early-stage breast cancer and high EZH2 expression. Breast Cancer Res Treat. 2012;132(2):429-437.
    • (2012) Breast Cancer Res Treat. , vol.132 , Issue.2 , pp. 429-437
    • Alford, S.H.1    Toy, K.2    Merajver, S.D.3    Kleer, C.G.4
  • 37
    • 79955652051 scopus 로고    scopus 로고
    • Enhancer of zeste homologue 2 expression in breast carcinoma smears in relationship with p53 Ki-67 and other prognostic parameters
    • Athanassiadou AM, Tsipis A, Patsouris E, et al. Enhancer of zeste homologue 2 expression in breast carcinoma smears in relationship with p53, Ki-67 and other prognostic parameters. Acta Cytol. 2011;55(2):180-186.
    • (2011) Acta Cytol. , vol.55 , Issue.2 , pp. 180-186
    • Athanassiadou, A.M.1    Tsipis, A.2    Patsouris, E.3
  • 38
    • 84861332826 scopus 로고    scopus 로고
    • Up-regulation of enhancer of zeste homolog 2 is associated positively with cyclin D1 overexpression and poor clinical outcome in head and neck squamous cell carcinoma
    • Cao W, Feng Z, Cui Z, et al. Up-regulation of enhancer of zeste homolog 2 is associated positively with cyclin D1 overexpression and poor clinical outcome in head and neck squamous cell carcinoma. Cancer. 2012;118(11):2858- 2871.
    • (2012) Cancer. , vol.118 , Issue.11 , pp. 2858-2871
    • Cao, W.1    Feng, Z.2    Cui, Z.3
  • 39
    • 33644765912 scopus 로고    scopus 로고
    • Expression of enhancer of zeste homologue 2 is significantly associated with increased tumor cell proliferation and is a marker of aggressive breast cancer
    • DOI 10.1158/1078-0432.CCR-05-1533
    • Collett K, Eide GE, Arnes J, et al. Expression of enhancer of zeste homologue 2 is significantly associated with increased tumor cell proliferation and is a marker of aggressive breast cancer. Clin Cancer Res. 2006;12(4):1168-1174. (Pubitemid 43342505)
    • (2006) Clinical Cancer Research , vol.12 , Issue.4 , pp. 1168-1174
    • Collett, K.1    Eide, G.E.2    Arnes, J.3    Stefansson, I.M.4    Eide, J.5    Braaten, A.6    Aas, T.7    Otte, A.P.8    Akslen, L.A.9
  • 40
    • 82555176159 scopus 로고    scopus 로고
    • Polycomb group protein EZH2 is frequently expressed in inflammatory breast cancer and is predictive of worse clinical outcome
    • Gong Y, Huo L, Liu P, et al. Polycomb group protein EZH2 is frequently expressed in inflammatory breast cancer and is predictive of worse clinical outcome. Cancer. 2011;117(24):5476-5484.
    • (2011) Cancer. , vol.117 , Issue.24 , pp. 5476-5484
    • Gong, Y.1    Huo, L.2    Liu, P.3
  • 41
    • 74249098871 scopus 로고    scopus 로고
    • Prognostic impact of H3K27me3 expression on locoregional progression after chemoradiotherapy in esophageal squamous cell carcinoma
    • He LR, Liu MZ, Li BK, et al. Prognostic impact of H3K27me3 expression on locoregional progression after chemoradiotherapy in esophageal squamous cell carcinoma. BMC Cancer. 2009;9:461.
    • (2009) BMC Cancer. , vol.9 , pp. 461
    • He, L.R.1    Liu, M.Z.2    Li, B.K.3
  • 42
    • 77953444201 scopus 로고    scopus 로고
    • High expression of EZH2 is associated with tumor aggressiveness and poor prognosis in patients with esophageal squamous cell carcinoma treated with definitive chemoradiotherapy
    • He LR, Liu MZ, Li BK, et al. High expression of EZH2 is associated with tumor aggressiveness and poor prognosis in patients with esophageal squamous cell carcinoma treated with definitive chemoradiotherapy. Int J Cancer. 2010; 127(1):138-147.
    • (2010) Int J Cancer. , vol.127 , Issue.1 , pp. 138-147
    • He, L.R.1    Liu, M.Z.2    Li, B.K.3
  • 43
    • 84866050864 scopus 로고    scopus 로고
    • Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes
    • Holm K, Grabau D, Lovgren K, et al. Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes. Mol Oncol. 2012;6(5):494-506.
    • (2012) Mol Oncol. , vol.6 , Issue.5 , pp. 494-506
    • Holm, K.1    Grabau, D.2    Lovgren, K.3
  • 44
    • 84857998198 scopus 로고    scopus 로고
    • Enhancer of zeste homolog 2 is a novel prognostic biomarker in nonsmall cell lung cancer
    • Huqun, Ishikawa R, Zhang J, et al. Enhancer of zeste homolog 2 is a novel prognostic biomarker in nonsmall cell lung cancer. Cancer. 2012;118(6):1599- 1606.
    • (2012) Cancer. , vol.118 , Issue.6 , pp. 1599-1606
    • Huqun Ishikawa, R.1    Zhang, J.2
  • 45
    • 84862956349 scopus 로고    scopus 로고
    • Enhancer of zeste homolog 2 overexpression in nasopharyngeal carcinoma: An independent poor prognosti-cator that enhances cell growth
    • Hwang CF, Huang HY, Chen CH, et al. Enhancer of zeste homolog 2 overexpression in nasopharyngeal carcinoma: an independent poor prognosti-cator that enhances cell growth. Int J Radiat Oncol Biol Phys. 2012;82(2):597-604.
    • (2012) Int J Radiat Oncol Biol Phys. , vol.82 , Issue.2 , pp. 597-604
    • Hwang, C.F.1    Huang, H.Y.2    Chen, C.H.3
  • 46
    • 57549115637 scopus 로고    scopus 로고
    • High expression of EZH2 is associated with tumor proliferation and prognosis in human oral squamous cell carcinomas
    • Kidani K, Osaki M, Tamura T, et al. High expression of EZH2 is associated with tumor proliferation and prognosis in human oral squamous cell carcinomas. Oral Oncol. 2009;45(1):39-46.
    • (2009) Oral Oncol. , vol.45 , Issue.1 , pp. 39-46
    • Kidani, K.1    Osaki, M.2    Tamura, T.3
  • 47
    • 77953978709 scopus 로고    scopus 로고
    • Distinctive expression of the polycomb group proteins Bmi1 polycomb ring finger oncogene and enhancer of zeste homolog 2 in nonsmall cell lung cancers and their clinical and clinicopathologic significance
    • Kikuchi J, Kinoshita I, Shimizu Y, et al. Distinctive expression of the polycomb group proteins Bmi1 polycomb ring finger oncogene and enhancer of zeste homolog 2 in nonsmall cell lung cancers and their clinical and clinicopathologic significance. Cancer. 2010;116(12):3015-3024.
    • (2010) Cancer. , vol.116 , Issue.12 , pp. 3015-3024
    • Kikuchi, J.1    Kinoshita, I.2    Shimizu, Y.3
  • 48
    • 70449433173 scopus 로고    scopus 로고
    • Carcinoma of the breast with medullary-like features: Diagnostic challenges and relationship with BRCA1 and EZH2 functions
    • Kleer CG. Carcinoma of the breast with medullary-like features: diagnostic challenges and relationship with BRCA1 and EZH2 functions. Arch Pathol Lab Med. 2009;133(11):1822-1825.
    • (2009) Arch Pathol Lab Med. , vol.133 , Issue.11 , pp. 1822-1825
    • Kleer, C.G.1
  • 50
    • 84866503477 scopus 로고    scopus 로고
    • Immunohistochem-ical analysis of polycomb group protein expression in advanced gastric cancer
    • Lee H, Yoon SO, Jeong WY, Kim HK, Kim A, Kim BH. Immunohistochem-ical analysis of polycomb group protein expression in advanced gastric cancer. Hum Pathol. 2012;43(10):1704-1710.
    • (2012) Hum Pathol. , vol.43 , Issue.10 , pp. 1704-1710
    • Lee, H.1    Yoon, S.O.2    Jeong, W.Y.3    Kim, H.K.4    Kim, A.5    Kim, B.H.6
  • 51
    • 80051786943 scopus 로고    scopus 로고
    • Overexpression of EZH2 and loss of expression of PTEN is associated with invasion, metastasis, and poor progression of gallbladder adenocarcinoma
    • Liu DC, Yang ZL. Overexpression of EZH2 and loss of expression of PTEN is associated with invasion, metastasis, and poor progression of gallbladder adenocarcinoma. Pathol Res Pract. 2011;207(8):472-478.
    • (2011) Pathol Res Pract. , vol.207 , Issue.8 , pp. 472-478
    • Liu, D.C.1    Yang, Z.L.2
  • 52
    • 33744519651 scopus 로고    scopus 로고
    • Expression of the enhancer of zeste homolog 2 is correlated with poor prognosis in human gastric cancer
    • DOI 10.1111/j.1349-7006.2006.00203.x
    • Matsukawa Y, Semba S, Kato H, Ito A, Yanagihara K, Yokozaki H. Expression of the enhancer of zeste homolog 2 is correlated with poor prognosis in human gastric cancer. Cancer Sci. 2006;97(6):484-491. (Pubitemid 43811589)
    • (2006) Cancer Science , vol.97 , Issue.6 , pp. 484-491
    • Matsukawa, Y.1    Semba, S.2    Kato, H.3    Ito, A.4    Yanagihara, K.5    Yokozaki, H.6
  • 53
    • 63849258988 scopus 로고    scopus 로고
    • EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer
    • Pietersen AM, Horlings HM, Hauptmann M, et al. EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer. Breast Cancer Res. 2008;10(6):R109.
    • (2008) Breast Cancer Res. , vol.10 , Issue.6
    • Pietersen, A.M.1    Horlings, H.M.2    Hauptmann, M.3
  • 54
    • 77956277833 scopus 로고    scopus 로고
    • EZH2 supports ovarian carcinoma cell invasion and/or metastasis via regulation of TGF-beta1 and is a predictor of outcome in ovarian carcinoma patients
    • Rao ZY, Cai MY, Yang GF, et al. EZH2 supports ovarian carcinoma cell invasion and/or metastasis via regulation of TGF-beta1 and is a predictor of outcome in ovarian carcinoma patients. Carcinogenesis. 2010;31(9):1576-1583.
    • (2010) Carcinogenesis. , vol.31 , Issue.9 , pp. 1576-1583
    • Rao, Z.Y.1    Cai, M.Y.2    Yang, G.F.3
  • 55
    • 78650987804 scopus 로고    scopus 로고
    • Decreased expression of EZH2 is associated with upregulation of ER and favorable outcome to tamoxifen in advanced breast cancer
    • Reijm EA, Jansen MP, Ruigrok-Ritstier K, et al. Decreased expression of EZH2 is associated with upregulation of ER and favorable outcome to tamoxifen in advanced breast cancer. Breast Cancer Res Treat. 2011;125(2):387-394.
    • (2011) Breast Cancer Res Treat. , vol.125 , Issue.2 , pp. 387-394
    • Reijm, E.A.1    Jansen, M.P.2    Ruigrok-Ritstier, K.3
  • 56
    • 79959267832 scopus 로고    scopus 로고
    • Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker
    • Takawa M, Masuda K, Kunizaki M, et al. Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker. Cancer Sci. 2011;102(7):1298-1305.
    • (2011) Cancer Sci. , vol.102 , Issue.7 , pp. 1298-1305
    • Takawa, M.1    Masuda, K.2    Kunizaki, M.3
  • 57
    • 77955924614 scopus 로고    scopus 로고
    • Implications of enhancer of zeste homologue 2 expression in pancreatic ductal adenocarcinoma
    • Toll AD, Dasgupta A, Potoczek M, et al. Implications of enhancer of zeste homologue 2 expression in pancreatic ductal adenocarcinoma. Hum Pathol. 2010;41(9):1205-1209.
    • (2010) Hum Pathol. , vol.41 , Issue.9 , pp. 1205-1209
    • Toll, A.D.1    Dasgupta, A.2    Potoczek, M.3
  • 60
    • 77953176278 scopus 로고    scopus 로고
    • EZH2 and STAT6 expression profiles are correlated with colorectal cancer stage and prognosis
    • Wang CG, Ye YJ, Yuan J, Liu FF, Zhang H, Wang S. EZH2 and STAT6 expression profiles are correlated with colorectal cancer stage and prognosis. World J Gastroenterol. 2010;16(19):2421-2427.
    • (2010) World J Gastroenterol. , vol.16 , Issue.19 , pp. 2421-2427
    • Wang, C.G.1    Ye, Y.J.2    Yuan, J.3    Liu, F.F.4    Zhang, H.5    Wang, S.6
  • 61
    • 71849116150 scopus 로고    scopus 로고
    • Expression profile of the polycomb group protein enhancer of Zeste homologue 2 and its prognostic relevance in renal cell carcinoma
    • Hinz S, Weikert S, Magheli A, et al. Expression profile of the polycomb group protein enhancer of Zeste homologue 2 and its prognostic relevance in renal cell carcinoma. J Urol. 2009;182(6):2920-2925.
    • (2009) J Urol. , vol.182 , Issue.6 , pp. 2920-2925
    • Hinz, S.1    Weikert, S.2    Magheli, A.3
  • 62
    • 50549103560 scopus 로고    scopus 로고
    • The enhancer of zeste homolog 2 gene contributes to cell proliferation and apoptosis resistance in renal cell carcinoma cells
    • Wagener N, Holland D, Bulkescher J, et al. The enhancer of zeste homolog 2 gene contributes to cell proliferation and apoptosis resistance in renal cell carcinoma cells. Int J Cancer. 2008;123(7):1545-1550.
    • (2008) Int J Cancer. , vol.123 , Issue.7 , pp. 1545-1550
    • Wagener, N.1    Holland, D.2    Bulkescher, J.3
  • 63
    • 77957282672 scopus 로고    scopus 로고
    • Enhancer of zeste homolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma
    • Wagener N, Macher-Goeppinger S, Pritsch M, et al. Enhancer of zeste homolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma. BMC Cancer. 2010;10:524.
    • (2010) BMC Cancer. , vol.10 , pp. 524
    • Wagener, N.1    MacHer-Goeppinger, S.2    Pritsch, M.3
  • 65
    • 84867987203 scopus 로고    scopus 로고
    • EZH2 inhibition: Targeting the crossroad of tumor invasion and angiogenesis
    • Crea F, Fornaro L, Bocci G, et al. EZH2 inhibition: targeting the crossroad of tumor invasion and angiogenesis. Cancer Metastasis Rev. 2012;31(3-4):753-761.
    • (2012) Cancer Metastasis Rev. , vol.31 , Issue.3-4 , pp. 753-761
    • Crea, F.1    Fornaro, L.2    Bocci, G.3
  • 66
    • 47749134140 scopus 로고    scopus 로고
    • Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation
    • Fujii S, Ito K, Ito Y, Ochiai A. Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation. J Biol Chem. 2008;283(25):17324-17332.
    • (2008) J Biol Chem. , vol.283 , Issue.25 , pp. 17324-17332
    • Fujii, S.1    Ito, K.2    Ito, Y.3    Ochiai, A.4
  • 67
    • 77956296864 scopus 로고    scopus 로고
    • The role of EZH2 and DNA methylation in the silencing of the tumour suppressor RUNX3 in colorectal cancer
    • Kodach LL, Jacobs RJ, Heijmans J, et al. The role of EZH2 and DNA methylation in the silencing of the tumour suppressor RUNX3 in colorectal cancer. Carcinogenesis. 2010;31(9):1567-1575.
    • (2010) Carcinogenesis. , vol.31 , Issue.9 , pp. 1567-1575
    • Kodach, L.L.1    Jacobs, R.J.2    Heijmans, J.3
  • 68
    • 79951723134 scopus 로고    scopus 로고
    • EZH2 regulates expression of p57 and contributes to progression of ovarian cancer in vitro and in vivo
    • Guo J, Cai J, Yu L, Tang H, Chen C, Wang Z. EZH2 regulates expression of p57 and contributes to progression of ovarian cancer in vitro and in vivo. Cancer Sci. 2011;102(3):530-539.
    • (2011) Cancer Sci. , vol.102 , Issue.3 , pp. 530-539
    • Guo, J.1    Cai, J.2    Yu, L.3    Tang, H.4    Chen, C.5    Wang, Z.6
  • 69
    • 80054940941 scopus 로고    scopus 로고
    • The tumor suppressor gene rap1GAP is silenced by miR-101-mediated EZH2 overexpression in invasive squamous cell carcinoma
    • Banerjee R, Mani RS, Russo N, et al. The tumor suppressor gene rap1GAP is silenced by miR-101-mediated EZH2 overexpression in invasive squamous cell carcinoma. Oncogene. 2011;30(42):4339-4349.
    • (2011) Oncogene. , vol.30 , Issue.42 , pp. 4339-4349
    • Banerjee, R.1    Mani, R.S.2    Russo, N.3
  • 70
    • 84863799452 scopus 로고    scopus 로고
    • Rap1 and its regulatory proteins: The tumor suppressor, oncogene, tumor suppressor gene axis in head and neck cancer
    • Banerjee R, Russo N, Liu M, Tubergen E, D'Silva N. Rap1 and its regulatory proteins: the tumor suppressor, oncogene, tumor suppressor gene axis in head and neck cancer. Small GTPases. 2012;3(3):192-197.
    • (2012) Small GTPases. , vol.3 , Issue.3 , pp. 192-197
    • Banerjee, R.1    Russo, N.2    Liu, M.3    Tubergen, E.4    D'Silva, N.5
  • 71
    • 34447125133 scopus 로고    scopus 로고
    • The gene encoding the prostatic tumor suppressor PSP94 is a target for repression by the Polycomb group protein EZH2
    • DOI 10.1038/sj.onc.1210248, PII 1210248
    • Beke L, Nuytten M, Van EA, Beullens M, Bollen M. The gene encoding the prostatic tumor suppressor PSP94 is a target for repression by the Polycomb group protein EZH2. Oncogene. 2007;26(31):4590-4595. (Pubitemid 47037047)
    • (2007) Oncogene , vol.26 , Issue.31 , pp. 4590-4595
    • Beke, L.1    Nuytten, M.2    Van Eynde, A.3    Beullens, M.4    Bollen, M.5
  • 72
    • 20444475352 scopus 로고    scopus 로고
    • Down-regulation of human DAB2IP gene expression mediated by polycomb Ezh2 complex and histone deacetylase in prostate cancer
    • DOI 10.1074/jbc.M501379200
    • Chen H, Tu SW, Hsieh JT. Down-regulation of human DAB2IP gene expression mediated by polycomb Ezh2 complex and histone deacetylase in prostate cancer. J Biol Chem. 2005;280(23):22437-22444. (Pubitemid 40827899)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.23 , pp. 22437-22444
    • Chen, H.1    Tu, S.-W.2    Hsieh, J.-T.3
  • 73
    • 84860255370 scopus 로고    scopus 로고
    • MicroRNA-26a regulates tumorigenic properties of EZH2 in human lung carcinoma cells
    • Dang X, Ma A, Yang L, et al. MicroRNA-26a regulates tumorigenic properties of EZH2 in human lung carcinoma cells. Cancer Genet. 2012;205(3): 113-123.
    • (2012) Cancer Genet. , vol.205 , Issue.3 , pp. 113-123
    • Dang, X.1    Ma, A.2    Yang, L.3
  • 74
    • 77749297990 scopus 로고    scopus 로고
    • An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB
    • Min J, Zaslavsky A, Fedele G, et al. An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB. Nat Med. 2010;16(3):286-294.
    • (2010) Nat Med. , vol.16 , Issue.3 , pp. 286-294
    • Min, J.1    Zaslavsky, A.2    Fedele, G.3
  • 75
    • 84864444749 scopus 로고    scopus 로고
    • EZH2-regulated DAB2IP is a medulloblastoma tumor suppressor and a positive marker for survival
    • Smits M, van Rijn S, Hulleman E, et al. EZH2-regulated DAB2IP is a medulloblastoma tumor suppressor and a positive marker for survival. Clin Cancer Res. 2012;18(15):4048-4058.
    • (2012) Clin Cancer Res. , vol.18 , Issue.15 , pp. 4048-4058
    • Smits, M.1    Van Rijn, S.2    Hulleman, E.3
  • 76
    • 79953862870 scopus 로고    scopus 로고
    • Enhancer of zeste homolog 2 overexpression has a role in the development of anaplastic thyroid carcinomas
    • Borbone E, Troncone G, Ferraro A, et al. Enhancer of zeste homolog 2 overexpression has a role in the development of anaplastic thyroid carcinomas. J Clin Endocrinol Metab. 2011;96(4):1029-1038.
    • (2011) J Clin Endocrinol Metab. , vol.96 , Issue.4 , pp. 1029-1038
    • Borbone, E.1    Troncone, G.2    Ferraro, A.3
  • 77
    • 41349104897 scopus 로고    scopus 로고
    • Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells
    • DOI 10.1111/j.1349-7006.2008.00743.x
    • Fujii S, Ochiai A. Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells. Cancer Sci. 2008; 99(4):738-746. (Pubitemid 351448078)
    • (2008) Cancer Science , vol.99 , Issue.4 , pp. 738-746
    • Fujii, S.1    Ochiai, A.2
  • 78
    • 84856533341 scopus 로고    scopus 로고
    • EZH2 supports nasopharyngeal carcinoma cell aggressiveness by forming a co-repressor complex with HDAC1/HDAC2 and Snail to inhibit E-cadherin
    • Tong ZT, Cai MY, Wang XG, et al. EZH2 supports nasopharyngeal carcinoma cell aggressiveness by forming a co-repressor complex with HDAC1/HDAC2 and Snail to inhibit E-cadherin. Oncogene. 2012;31(5):583-594.
    • (2012) Oncogene. , vol.31 , Issue.5 , pp. 583-594
    • Tong, Z.T.1    Cai, M.Y.2    Wang, X.G.3
  • 79
    • 84873273556 scopus 로고    scopus 로고
    • Polycomb group protein EZH2-mediated E-cadherin repression promotes metastasis of oral tongue squamous cell carcinoma [published online ahead of print December 7, 2011
    • doi:10. 1002/mc.21848
    • Wang C, Liu X, Chen Z, et al. Polycomb group protein EZH2-mediated E-cadherin repression promotes metastasis of oral tongue squamous cell carcinoma [published online ahead of print December 7, 2011]. Mol Carcinog 54. doi:10. 1002/mc.21848.
    • Mol Carcinog , vol.54
    • Wang, C.1    Liu, X.2    Chen, Z.3
  • 80
    • 84856221154 scopus 로고    scopus 로고
    • FOXC1, a target of polycomb, inhibits metastasis of breast cancer cells
    • Du J, Li L, Ou Z, et al. FOXC1, a target of polycomb, inhibits metastasis of breast cancer cells. Breast Cancer Res Treat. 2012;131(1):65-73.
    • (2012) Breast Cancer Res Treat. , vol.131 , Issue.1 , pp. 65-73
    • Du, J.1    Li, L.2    Ou, Z.3
  • 81
    • 84862560519 scopus 로고    scopus 로고
    • Polycomb protein EZH2 regulates tumor invasion via the transcriptional repression of the metastasis suppressor RKIP in breast and prostate cancer
    • Ren G, Baritaki S, Marathe H, et al. Polycomb protein EZH2 regulates tumor invasion via the transcriptional repression of the metastasis suppressor RKIP in breast and prostate cancer. Cancer Res. 2012;72(12):3091-3104.
    • (2012) Cancer Res. , vol.72 , Issue.12 , pp. 3091-3104
    • Ren, G.1    Baritaki, S.2    Marathe, H.3
  • 82
    • 84863969631 scopus 로고    scopus 로고
    • Cancer angiogenesis induced by Kaposi sarcoma-associated herpesvirus is mediated by EZH2
    • He M, Zhang W, Bakken T, et al. Cancer angiogenesis induced by Kaposi sarcoma-associated herpesvirus is mediated by EZH2. Cancer Res. 2012;72(14): 3582-3592.
    • (2012) Cancer Res. , vol.72 , Issue.14 , pp. 3582-3592
    • He, M.1    Zhang, W.2    Bakken, T.3
  • 83
    • 77955541508 scopus 로고    scopus 로고
    • Regulation of tumor angiogenesis by EZH2
    • Lu C, Han HD, Mangala LS, et al. Regulation of tumor angiogenesis by EZH2. Cancer Cell. 2010;18(2):185-197.
    • (2010) Cancer Cell. , vol.18 , Issue.2 , pp. 185-197
    • Lu, C.1    Han, H.D.2    Mangala, L.S.3
  • 84
    • 34447335892 scopus 로고    scopus 로고
    • Expression of polycomb group protein EZH2 in nevi and melanoma
    • DOI 10.1111/j.1600-0560.2006.00678.x
    • McHugh JB, Fullen DR, Ma L, Kleer CG, Su LD. Expression of polycomb group protein EZH2 in nevi and melanoma. J Cutan Pathol. 2007;34(8):597-600. (Pubitemid 47063232)
    • (2007) Journal of Cutaneous Pathology , vol.34 , Issue.8 , pp. 597-600
    • McHugh, J.B.1    Fullen, D.R.2    Ma, L.3    Kleer, C.G.4    Su, L.D.5
  • 85
    • 84865339061 scopus 로고    scopus 로고
    • Targeting the enhancer of zeste homologue 2 in medulloblastoma
    • Alimova I, Venkataraman S, Harris P, et al. Targeting the enhancer of zeste homologue 2 in medulloblastoma. Int J Cancer. 2012;131(8):1800-1809.
    • (2012) Int J Cancer. , vol.131 , Issue.8 , pp. 1800-1809
    • Alimova, I.1    Venkataraman, S.2    Harris, P.3
  • 86
    • 53649093784 scopus 로고    scopus 로고
    • Accumulation of malignant renal stem cells is associated with epigenetic changes in normal renal progenitor genes
    • Metsuyanim S, Pode-Shakked N, Schmidt-Ott KM, et al. Accumulation of malignant renal stem cells is associated with epigenetic changes in normal renal progenitor genes. Stem Cells. 2008;26(7):1808-1817.
    • (2008) Stem Cells. , vol.26 , Issue.7 , pp. 1808-1817
    • Metsuyanim, S.1    Pode-Shakked, N.2    Schmidt-Ott, K.M.3
  • 88
    • 84865122721 scopus 로고    scopus 로고
    • Invasive breast carcinomas in Ghana: High frequency of high grade, basal-like histology and high EZH2 expression
    • Pang J, Toy KA, Griffith KA, et al. Invasive breast carcinomas in Ghana: high frequency of high grade, basal-like histology and high EZH2 expression. Breast Cancer Res Treat. 2012;135(1):59-66.
    • (2012) Breast Cancer Res Treat. , vol.135 , Issue.1 , pp. 59-66
    • Pang, J.1    Toy, K.A.2    Griffith, K.A.3
  • 89
    • 84864112566 scopus 로고    scopus 로고
    • Co-expression of Bmi1 and EZH2 as an independent poor prognostic factor in esophageal squamous cell carcinoma
    • Ha SY, Kim SH. Co-expression of Bmi1 and EZH2 as an independent poor prognostic factor in esophageal squamous cell carcinoma. Pathol Res Pract. 2012;208(8):462-469.
    • (2012) Pathol Res Pract. , vol.208 , Issue.8 , pp. 462-469
    • Ha, S.Y.1    Kim, S.H.2
  • 90
    • 76149136889 scopus 로고    scopus 로고
    • Enhancer of zeste homolog 2 expression is associated with tumor cell proliferation and metastasis in gastric cancer
    • Choi JH, Song YS, Yoon JS, Song KW, Lee YY. Enhancer of zeste homolog 2 expression is associated with tumor cell proliferation and metastasis in gastric cancer. APMIS. 2010;118(3):196-202.
    • (2010) APMIS. , vol.118 , Issue.3 , pp. 196-202
    • Choi, J.H.1    Song, Y.S.2    Yoon, J.S.3    Song, K.W.4    Lee, Y.Y.5
  • 91
    • 78650493658 scopus 로고    scopus 로고
    • Enhancer of zeste homolog 2 promotes the proliferation and invasion of epithelial ovarian cancer cells
    • Li H, Cai Q, Godwin AK, Zhang R. Enhancer of zeste homolog 2 promotes the proliferation and invasion of epithelial ovarian cancer cells. Mol Cancer Res. 2010;8(12):1610-1618.
    • (2010) Mol Cancer Res. , vol.8 , Issue.12 , pp. 1610-1618
    • Li, H.1    Cai, Q.2    Godwin, A.K.3    Zhang, R.4
  • 92
    • 48749104292 scopus 로고    scopus 로고
    • The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma
    • Sasaki M, Ikeda H, Itatsu K, et al. The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma. Lab Invest. 2008;88(8):873-882.
    • (2008) Lab Invest. , vol.88 , Issue.8 , pp. 873-882
    • Sasaki, M.1    Ikeda, H.2    Itatsu, K.3
  • 94
    • 29344445843 scopus 로고    scopus 로고
    • Increased expression of the polycomb group gene, EZH2, in transitional cell carcinoma of the bladder
    • DOI 10.1158/1078-0432.CCR-05-1047
    • Raman JD, Mongan NP, Tickoo SK, Boorjian SA, Scherr DS, Gudas LJ. Increased expression of the polycomb group gene, EZH2, in transitional cell carcinoma of the bladder. Clin Cancer Res. 2005;11(24, pt 1):8570-8576. (Pubitemid 43005902)
    • (2005) Clinical Cancer Research , vol.11 , Issue.24 , pp. 8570-8576
    • Raman, J.D.1    Mongan, N.P.2    Tickoo, S.K.3    Boorjian, S.A.4    Scherr, D.S.5    Gudas, L.J.6
  • 95
    • 77957120443 scopus 로고    scopus 로고
    • Deregulation of EZH2 expression in human spermatogenic disorders and testicular germ cell tumors
    • Hinz S, Magheli A, Weikert S, et al. Deregulation of EZH2 expression in human spermatogenic disorders and testicular germ cell tumors. World J Urol. 2010;28(5):631-635.
    • (2010) World J Urol. , vol.28 , Issue.5 , pp. 631-635
    • Hinz, S.1    Magheli, A.2    Weikert, S.3
  • 96
    • 70349958032 scopus 로고    scopus 로고
    • Expression of EZH2 and Ki-67 in colorectal cancer and associations with treatment response and prognosis
    • Fluge O, Gravdal K, Carlsen E, et al. Expression of EZH2 and Ki-67 in colorectal cancer and associations with treatment response and prognosis. Br J Cancer. 2009;101(8):1282-1289.
    • (2009) Br J Cancer. , vol.101 , Issue.8 , pp. 1282-1289
    • Fluge, O.1    Gravdal, K.2    Carlsen, E.3
  • 97
    • 79956132811 scopus 로고    scopus 로고
    • High-grade neuroendocrine carcinomas of the lung highly express enhancer of zeste homolog 2, but carcinoids do not
    • Findeis-Hosey JJ, Huang J, Li F, Yang Q, McMahon LA, Xu H. High-grade neuroendocrine carcinomas of the lung highly express enhancer of zeste homolog 2, but carcinoids do not. Hum Pathol. 2011;42(6):867-872.
    • (2011) Hum Pathol. , vol.42 , Issue.6 , pp. 867-872
    • Findeis-Hosey, J.J.1    Huang, J.2    Li, F.3    Yang, Q.4    McMahon, L.A.5    Xu, H.6
  • 98
    • 84863690032 scopus 로고    scopus 로고
    • Prognostic impact of the cancer stem cell related markers ALDH1 and EZH2 in triple negative and basal-like breast cancers
    • De Brot M, Rocha RM, Soares FA, Gobbi H. Prognostic impact of the cancer stem cell related markers ALDH1 and EZH2 in triple negative and basal-like breast cancers. Pathology. 2012;44(4):303-312.
    • (2012) Pathology. , vol.44 , Issue.4 , pp. 303-312
    • De Brot, M.1    Rocha, R.M.2    Soares, F.A.3    Gobbi, H.4


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