A macrocyclic peptide that serves as a cocrystallization ligand and inhibits the function of a MATE family transporter

Molecules

Volumn 18, Issue 9, 2013, Pages 10514-10530

  Hipolito, Christopher J ^a   Tanaka, Yoshiki ^a,b   Katoh, Takayuki ^a   Nureki, Osamu ^a   Suga, Hiroaki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b KYOTO UNIVERSITY FACULTY OF MEDICINE   (Japan)

Author keywords

Cocrystallization ligand; In vitro selection; Macrocyclic peptide; PfMATE; Random non standard peptide integrated discovery (RaPID)

Indexed keywords

ANTIPORTER; ARCHAEAL PROTEIN; CYCLOPEPTIDE; ETHIDIUM; FLUORESCENT DYE; LIGAND; PROTEIN BINDING;

AMINO ACID SEQUENCE; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; CRYSTALLIZATION; DRUG DEVELOPMENT; ESCHERICHIA COLI; METABOLISM; MOLECULAR GENETICS; MULTIDRUG RESISTANCE; PROTEIN SECONDARY STRUCTURE; PYROCOCCUS FURIOSUS; X RAY CRYSTALLOGRAPHY; ARTICLE; DRUG ANTAGONISM; PROTEIN BINDING;

AMINO ACID SEQUENCE; ANTIPORTERS; ARCHAEAL PROTEINS; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DRUG DISCOVERY; DRUG RESISTANCE, MULTIPLE; ESCHERICHIA COLI; ETHIDIUM; FLUORESCENT DYES; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES, CYCLIC; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PYROCOCCUS FURIOSUS;

EID: 84885151475     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules180910514     Document Type: Article

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