Natural product-like macrocyclic N-methyl-peptide inhibitors against a ubiquitin ligase uncovered from a ribosome-expressed de novo library

Chemistry and Biology

Volumn 18, Issue 12, 2011, Pages 1562-1570

  Yamagishi, Yusuke ^a   Shoji, Ikuo ^b   Miyagawa, Shoji ^b   Kawakami, Takashi ^a   Katoh, Takayuki ^a   Goto, Yuki ^a   Suga, Hiroaki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL PRODUCT; MACROCYCLIC COMPOUND; PEPTIDE; PROTEIN P53; UBIQUITIN PROTEIN LIGASE;

AMINO ACID SEQUENCE; ARTICLE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; METHYLATION; PEPTIDE LIBRARY; PROTEIN TERTIARY STRUCTURE; RIBOSOME; UBIQUITINATION;

AMINO ACID SEQUENCE; BIOLOGICAL AGENTS; MACROCYCLIC COMPOUNDS; METHYLATION; PEPTIDE LIBRARY; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; RIBOSOMES; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84555190565     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2011.09.013     Document Type: Article

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