-
1
-
-
0036187615
-
The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
-
L. Bingle, N.J. Brown, and C.E. Lewis The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies J. Pathol. 196 2002 254 265
-
(2002)
J. Pathol.
, vol.196
, pp. 254-265
-
-
Bingle, L.1
Brown, N.J.2
Lewis, C.E.3
-
2
-
-
33644825565
-
Dynamic imaging of protease activity with fluorescently quenched activity-based probes
-
G. Blum, S.R. Mullins, K. Keren, M. Fonovic, C. Jedeszko, M.J. Rice, B.F. Sloane, and M. Bogyo Dynamic imaging of protease activity with fluorescently quenched activity-based probes Nat. Chem. Biol. 1 2005 203 209
-
(2005)
Nat. Chem. Biol.
, vol.1
, pp. 203-209
-
-
Blum, G.1
Mullins, S.R.2
Keren, K.3
Fonovic, M.4
Jedeszko, C.5
Rice, M.J.6
Sloane, B.F.7
Bogyo, M.8
-
3
-
-
34548666006
-
Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes
-
G. Blum, G. von Degenfeld, M.J. Merchant, H.M. Blau, and M. Bogyo Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes Nat. Chem. Biol. 3 2007 668 677
-
(2007)
Nat. Chem. Biol.
, vol.3
, pp. 668-677
-
-
Blum, G.1
Von Degenfeld, G.2
Merchant, M.J.3
Blau, H.M.4
Bogyo, M.5
-
4
-
-
79960412246
-
Myeloid suppressor cells regulate the lung environment - Letter
-
author reply 5052-5053
-
M. Bosiljcic, M.J. Hamilton, J.P. Banath, N.E. Lepard, D.C. McDougal, J.X. Jia, G. Krystal, and K.L. Bennewith Myeloid suppressor cells regulate the lung environment - letter Cancer Res. 71 2011 5050 5051 author reply 5052-5053
-
(2011)
Cancer Res.
, vol.71
, pp. 5050-5051
-
-
Bosiljcic, M.1
Hamilton, M.J.2
Banath, J.P.3
Lepard, N.E.4
McDougal, D.C.5
Jia, J.X.6
Krystal, G.7
Bennewith, K.L.8
-
5
-
-
77955390094
-
Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella
-
P. Broz, K. Newton, M. Lamkanfi, S. Mariathasan, V.M. Dixit, and D.M. Monack Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella J. Exp. Med. 207 2010 1745 1755
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1745-1755
-
-
Broz, P.1
Newton, K.2
Lamkanfi, M.3
Mariathasan, S.4
Dixit, V.M.5
Monack, D.M.6
-
6
-
-
79551503110
-
Functional in vivo imaging of cysteine cathepsin activity in murine model of inflammation
-
D. Caglič, A. Globisch, M. Kindermann, N.H. Lim, V. Jeske, H.P. Juretschke, E. Bartnik, K.U. Weithmann, H. Nagase, B. Turk, and K.U. Wendt Functional in vivo imaging of cysteine cathepsin activity in murine model of inflammation Bioorg. Med. Chem. 19 2011 1055 1061
-
(2011)
Bioorg. Med. Chem.
, vol.19
, pp. 1055-1061
-
-
Caglič, D.1
Globisch, A.2
Kindermann, M.3
Lim, N.H.4
Jeske, V.5
Juretschke, H.P.6
Bartnik, E.7
Weithmann, K.U.8
Nagase, H.9
Turk, B.10
Wendt, K.U.11
-
7
-
-
67650151005
-
Cancer-related inflammation, the seventh hallmark of cancer: Links to genetic instability
-
F. Colotta, P. Allavena, A. Sica, C. Garlanda, and A. Mantovani Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability Carcinogenesis 30 2009 1073 1081
-
(2009)
Carcinogenesis
, vol.30
, pp. 1073-1081
-
-
Colotta, F.1
Allavena, P.2
Sica, A.3
Garlanda, C.4
Mantovani, A.5
-
8
-
-
82755167524
-
Cathepsins and their involvement in immune responses
-
S. Conus, and H.U. Simon Cathepsins and their involvement in immune responses Swiss Med. Wkly. 140 2010 w13042
-
(2010)
Swiss Med. Wkly.
, vol.140
, pp. 13042
-
-
Conus, S.1
Simon, H.U.2
-
9
-
-
62449179631
-
Granulocyte macrophage colony-stimulating factor inhibits breast cancer growth and metastasis by invoking an anti-angiogenic program in tumor-educated macrophages
-
T.D. Eubank, R.D. Roberts, M. Khan, J.M. Curry, G.J. Nuovo, P. Kuppusamy, and C.B. Marsh Granulocyte macrophage colony-stimulating factor inhibits breast cancer growth and metastasis by invoking an anti-angiogenic program in tumor-educated macrophages Cancer Res. 69 2009 2133 2140
-
(2009)
Cancer Res.
, vol.69
, pp. 2133-2140
-
-
Eubank, T.D.1
Roberts, R.D.2
Khan, M.3
Curry, J.M.4
Nuovo, G.J.5
Kuppusamy, P.6
Marsh, C.B.7
-
10
-
-
80052359505
-
Renal collecting duct epithelial cells regulate inflammation in tubulointerstitial damage in mice
-
K. Fujiu, I. Manabe, and R. Nagai Renal collecting duct epithelial cells regulate inflammation in tubulointerstitial damage in mice J. Clin. Invest. 121 2011 3425 3441
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 3425-3441
-
-
Fujiu, K.1
Manabe, I.2
Nagai, R.3
-
11
-
-
33846643454
-
Cysteine cathepsins and the cutting edge of cancer invasion
-
V. Gocheva, and J.A. Joyce Cysteine cathepsins and the cutting edge of cancer invasion Cell Cycle 6 2007 60 64
-
(2007)
Cell Cycle
, vol.6
, pp. 60-64
-
-
Gocheva, V.1
Joyce, J.A.2
-
12
-
-
76149146398
-
IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion
-
V. Gocheva, H.W. Wang, B.B. Gadea, T. Shree, K.E. Hunter, A.L. Garfall, T. Berman, and J.A. Joyce IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion Genes Dev. 24 2010 241 255
-
(2010)
Genes Dev.
, vol.24
, pp. 241-255
-
-
Gocheva, V.1
Wang, H.W.2
Gadea, B.B.3
Shree, T.4
Hunter, K.E.5
Garfall, A.L.6
Berman, T.7
Joyce, J.A.8
-
13
-
-
51449115025
-
Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth
-
E. Gounaris, C.H. Tung, C. Restaino, R. Maehr, R. Kohler, J.A. Joyce, H.L. Ploegh, T.A. Barrett, R. Weissleder, and K. Khazaie Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth PLoS ONE 3 2008 e2916
-
(2008)
PLoS ONE
, vol.3
, pp. 2916
-
-
Gounaris, E.1
Tung, C.H.2
Restaino, C.3
Maehr, R.4
Kohler, R.5
Joyce, J.A.6
Ploegh, H.L.7
Barrett, T.A.8
Weissleder, R.9
Khazaie, K.10
-
14
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
D. Hanahan, and R.A. Weinberg Hallmarks of cancer: the next generation Cell 144 2011 646 674
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
15
-
-
0024814219
-
Cathepsin S from bovine spleen: Purification, distribution, intracellular localization and action on proteins
-
H. Kirschke, B. Wiederanders, D. Brömme, and A. Rinne Cathepsin S from bovine spleen: purification, distribution, intracellular localization and action on proteins Biochem. J. 264 1989 467 473
-
(1989)
Biochem. J.
, vol.264
, pp. 467-473
-
-
Kirschke, H.1
Wiederanders, B.2
Brömme, D.3
Rinne, A.4
-
16
-
-
79954600458
-
Significance of M2-polarized tumor-associated macrophage in pancreatic cancer
-
H. Kurahara, H. Shinchi, Y. Mataki, K. Maemura, H. Noma, F. Kubo, M. Sakoda, S. Ueno, S. Natsugoe, and S. Takao Significance of M2-polarized tumor-associated macrophage in pancreatic cancer J. Surg. Res. 167 2011 e211 e219
-
(2011)
J. Surg. Res.
, vol.167
-
-
Kurahara, H.1
Shinchi, H.2
Mataki, Y.3
Maemura, K.4
Noma, H.5
Kubo, F.6
Sakoda, M.7
Ueno, S.8
Natsugoe, S.9
Takao, S.10
-
17
-
-
78049353699
-
Tumor cell-released TLR4 ligands stimulate Gr-1+CD11b+F4/80+ cells to induce apoptosis of activated T cells
-
Y.Y. Liu, L.C. Sun, J.J. Wei, D. Li, Y. Yuan, B. Yan, Z.H. Liang, H.F. Zhu, Y. Xu, and B. Li Tumor cell-released TLR4 ligands stimulate Gr-1+CD11b+F4/80+ cells to induce apoptosis of activated T cells J. Immunol. 185 2010 2773 2782
-
(2010)
J. Immunol.
, vol.185
, pp. 2773-2782
-
-
Liu, Y.Y.1
Sun, L.C.2
Wei, J.J.3
Li, D.4
Yuan, Y.5
Yan, B.6
Liang, Z.H.7
Zhu, H.F.8
Xu, Y.9
Li, B.10
-
18
-
-
0344438130
-
Near-infrared optical imaging of proteases in cancer
-
U. Mahmood, and R. Weissleder Near-infrared optical imaging of proteases in cancer Mol. Cancer Ther. 2 2003 489 496
-
(2003)
Mol. Cancer Ther.
, vol.2
, pp. 489-496
-
-
Mahmood, U.1
Weissleder, R.2
-
20
-
-
33749017931
-
Cysteine cathepsins: Multifunctional enzymes in cancer
-
M.M. Mohamed, and B.F. Sloane Cysteine cathepsins: multifunctional enzymes in cancer Nat. Rev. Cancer 6 2006 764 775
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 764-775
-
-
Mohamed, M.M.1
Sloane, B.F.2
-
21
-
-
56749174940
-
Exploring the full spectrum of macrophage activation
-
D.M. Mosser, and J.P. Edwards Exploring the full spectrum of macrophage activation Nat. Rev. Immunol. 8 2008 958 969
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 958-969
-
-
Mosser, D.M.1
Edwards, J.P.2
-
22
-
-
33748524564
-
Antiamyloidogenic and neuroprotective functions of cathepsin B: Implications for Alzheimer's disease
-
S. Mueller-Steiner, Y. Zhou, H. Arai, E.D. Roberson, B. Sun, J. Chen, X. Wang, G. Yu, L. Esposito, L. Mucke, and L. Gan Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease Neuron 51 2006 703 714
-
(2006)
Neuron
, vol.51
, pp. 703-714
-
-
Mueller-Steiner, S.1
Zhou, Y.2
Arai, H.3
Roberson, E.D.4
Sun, B.5
Chen, J.6
Wang, X.7
Yu, G.8
Esposito, L.9
Mucke, L.10
Gan, L.11
-
23
-
-
78650547508
-
Tumor-associated macrophages in breast cancer as potential biomarkers for new treatments and diagnostics
-
R.A. Mukhtar, O. Nseyo, M.J. Campbell, and L.J. Esserman Tumor-associated macrophages in breast cancer as potential biomarkers for new treatments and diagnostics Expert Rev. Mol. Diagn. 11 2011 91 100
-
(2011)
Expert Rev. Mol. Diagn.
, vol.11
, pp. 91-100
-
-
Mukhtar, R.A.1
Nseyo, O.2
Campbell, M.J.3
Esserman, L.J.4
-
24
-
-
33750125526
-
Identification of selective, nonpeptidic nitrile inhibitors of cathepsin s using the substrate activity screening method
-
A.W. Patterson, W.J. Wood, M. Hornsby, S. Lesley, G. Spraggon, and J.A. Ellman Identification of selective, nonpeptidic nitrile inhibitors of cathepsin s using the substrate activity screening method J. Med. Chem. 49 2006 6298 6307
-
(2006)
J. Med. Chem.
, vol.49
, pp. 6298-6307
-
-
Patterson, A.W.1
Wood, W.J.2
Hornsby, M.3
Lesley, S.4
Spraggon, G.5
Ellman, J.A.6
-
25
-
-
77950950894
-
Macrophage diversity enhances tumor progression and metastasis
-
B.Z. Qian, and J.W. Pollard Macrophage diversity enhances tumor progression and metastasis Cell 141 2010 39 51
-
(2010)
Cell
, vol.141
, pp. 39-51
-
-
Qian, B.Z.1
Pollard, J.W.2
-
26
-
-
79953757620
-
Molecular imaging of macrophage protease activity in cardiovascular inflammation in vivo
-
T. Quillard, K. Croce, F.A. Jaffer, R. Weissleder, and P. Libby Molecular imaging of macrophage protease activity in cardiovascular inflammation in vivo Thromb. Haemost. 105 2011 828 836
-
(2011)
Thromb. Haemost.
, vol.105
, pp. 828-836
-
-
Quillard, T.1
Croce, K.2
Jaffer, F.A.3
Weissleder, R.4
Libby, P.5
-
27
-
-
77957855881
-
Specialized roles for cysteine cathepsins in health and disease
-
J. Reiser, B. Adair, and T. Reinheckel Specialized roles for cysteine cathepsins in health and disease J. Clin. Invest. 120 2010 3421 3431
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 3421-3431
-
-
Reiser, J.1
Adair, B.2
Reinheckel, T.3
-
28
-
-
77949345555
-
Tumor-associated macrophages and survival in classic Hodgkin's lymphoma
-
C. Steidl, T. Lee, S.P. Shah, P. Farinha, G. Han, T. Nayar, A. Delaney, S.J. Jones, J. Iqbal, and D.D. Weisenburger Tumor-associated macrophages and survival in classic Hodgkin's lymphoma N. Engl. J. Med. 362 2010 875 885
-
(2010)
N. Engl. J. Med.
, vol.362
, pp. 875-885
-
-
Steidl, C.1
Lee, T.2
Shah, S.P.3
Farinha, P.4
Han, G.5
Nayar, T.6
Delaney, A.7
Jones, S.J.8
Iqbal, J.9
Weisenburger, D.D.10
-
29
-
-
51349151553
-
Imagable 4T1 model for the study of late stage breast cancer
-
K. Tao, M. Fang, J. Alroy, and G.G. Sahagian Imagable 4T1 model for the study of late stage breast cancer BMC Cancer 8 2008 228
-
(2008)
BMC Cancer
, vol.8
, pp. 228
-
-
Tao, K.1
Fang, M.2
Alroy, J.3
Sahagian, G.G.4
-
30
-
-
0035801514
-
Lysosomal cysteine proteases: Facts and opportunities
-
V. Turk, B. Turk, and D. Turk Lysosomal cysteine proteases: facts and opportunities EMBO J. 20 2001 4629 4633
-
(2001)
EMBO J.
, vol.20
, pp. 4629-4633
-
-
Turk, V.1
Turk, B.2
Turk, D.3
-
31
-
-
27644555726
-
Substrate activity screening: A fragment-based method for the rapid identification of nonpeptidic protease inhibitors
-
W.J. Wood, A.W. Patterson, H. Tsuruoka, R.K. Jain, and J.A. Ellman Substrate activity screening: a fragment-based method for the rapid identification of nonpeptidic protease inhibitors J. Am. Chem. Soc. 127 2005 15521 15527
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 15521-15527
-
-
Wood, W.J.1
Patterson, A.W.2
Tsuruoka, H.3
Jain, R.K.4
Ellman, J.A.5
-
32
-
-
33646513917
-
Cysteine cathepsins in the immune response
-
T. Zavasnik-Bergant, and B. Turk Cysteine cathepsins in the immune response Tissue Antigens 67 2006 349 355
-
(2006)
Tissue Antigens
, vol.67
, pp. 349-355
-
-
Zavasnik-Bergant, T.1
Turk, B.2
|