메뉴 건너뛰기




Volumn 73, Issue 19, 2013, Pages 5892-5904

Dysregulated hematopoiesiscausedbymammary Cancer is associated with epigenetic changes and Hox gene expression in hematopoietic cells

Author keywords

[No Author keywords available]

Indexed keywords

FLT3 LIGAND; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; POLYCOMB REPRESSIVE COMPLEX 2; STEM CELL FACTOR RECEPTOR; FLT3 LIGAND PROTEIN; HISTONE; MEMBRANE PROTEIN; MESSENGER RNA;

EID: 84885065133     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-0842     Document Type: Article
Times cited : (41)

References (50)
  • 3
    • 77954255971 scopus 로고    scopus 로고
    • Cancer-associated myeloproliferation: Old association, new therapeutic target
    • Wilcox RA. Cancer-associated myeloproliferation: old association, new therapeutic target. Mayo Clin Proc 2010;85:656-63.
    • (2010) Mayo Clin Proc , vol.85 , pp. 656-663
    • Wilcox, R.A.1
  • 4
    • 78449245411 scopus 로고    scopus 로고
    • Incidence of anemia, leukocytosis, and thrombocytosis in patients with solid tumors in China
    • Qiu MZ, Xu RH, Ruan DY, Li ZH, Luo HY, Teng KY, et al. Incidence of anemia, leukocytosis, and thrombocytosis in patients with solid tumors in China. Tumour Biol 2010;31:633-41.
    • (2010) Tumour Biol , vol.31 , pp. 633-641
    • Qiu, M.Z.1    Xu, R.H.2    Ruan, D.Y.3    Li, Z.H.4    Luo, H.Y.5    Teng, K.Y.6
  • 5
    • 79952093380 scopus 로고    scopus 로고
    • Histopathologic-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction
    • Mlecnik B, Tosolini M, Kirilovsky A, Berger A, Bindea G, Meatchi T, et al. Histopathologic-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction. J Clin Oncol 2011;29:610-8.
    • (2011) J Clin Oncol , vol.29 , pp. 610-618
    • Mlecnik, B.1    Tosolini, M.2    Kirilovsky, A.3    Berger, A.4    Bindea, G.5    Meatchi, T.6
  • 6
    • 51049108540 scopus 로고    scopus 로고
    • Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma
    • Quezada SA, Peggs KS, Simpson TR, Shen Y, Littman DR, Allison JP. Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma. J Exp Med 2008;205:2125-38.
    • (2008) J Exp Med , vol.205 , pp. 2125-2138
    • Quezada, S.A.1    Peggs, K.S.2    Simpson, T.R.3    Shen, Y.4    Littman, D.R.5    Allison, J.P.6
  • 7
    • 79959674418 scopus 로고    scopus 로고
    • Epigenetics of haematopoietic cell development
    • Cedar H, Bergman Y. Epigenetics of haematopoietic cell development. Nat Rev Immunol 2011;11:478-88.
    • (2011) Nat Rev Immunol , vol.11 , pp. 478-488
    • Cedar, H.1    Bergman, Y.2
  • 8
    • 77955085750 scopus 로고    scopus 로고
    • Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
    • Ernst T, Chase AJ, Score J, Hidalgo-Curtis CE, Bryant C, Jones AV, et al. Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders. Nat Genet 2010;42:722-6.
    • (2010) Nat Genet , vol.42 , pp. 722-726
    • Ernst, T.1    Chase, A.J.2    Score, J.3    Hidalgo-Curtis, C.E.4    Bryant, C.5    Jones, A.V.6
  • 9
    • 77957154350 scopus 로고    scopus 로고
    • Throwing the cancer switch: Reciprocal roles of Polycomb and Trithorax proteins
    • Mills AA. Throwing the cancer switch: reciprocal roles of Polycomb and Trithorax proteins. Nat Rev Cancer 2010;10:669-82.
    • (2010) Nat Rev Cancer , vol.10 , pp. 669-682
    • Mills, A.A.1
  • 10
    • 0036830642 scopus 로고    scopus 로고
    • Role of histone H3 lysine 27 methylation in Polycomb-group silencing
    • Cao R, Wang L, Wang H, Xia L, Erdjument-Bromage H, Tempst P, et al. Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science 2002;298:1039-43.
    • (2002) Science , vol.298 , pp. 1039-1043
    • Cao, R.1    Wang, L.2    Wang, H.3    Xia, L.4    Erdjument-Bromage, H.5    Tempst, P.6
  • 11
    • 3042801308 scopus 로고    scopus 로고
    • SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex
    • Cao R, Zhang Y. SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex. Mol Cell 2004;15:57-67.
    • (2004) Mol Cell , vol.15 , pp. 57-67
    • Cao, R.1    Zhang, Y.2
  • 14
    • 0032722268 scopus 로고    scopus 로고
    • The role of homeobox genes in normal hematopoiesis and hematological malignancies
    • van Oostveen J, Bijl J, Raaphorst F, Walboomers J, Meijer C. The role of homeobox genes in normal hematopoiesis and hematological malignancies. Leukemia 1999;13:1675-90.
    • (1999) Leukemia , vol.13 , pp. 1675-1690
    • Van Oostveen, J.1    Bijl, J.2    Raaphorst, F.3    Walboomers, J.4    Meijer, C.5
  • 15
    • 34548644772 scopus 로고    scopus 로고
    • The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of Polycomb-mediated gene silencing
    • De Santa F, Totaro MG, Prosperini E, Notarbartolo S, Testa G, Natoli G. The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of Polycomb-mediated gene silencing. Cell 2007;130:1083-94.
    • (2007) Cell , vol.130 , pp. 1083-1094
    • De Santa, F.1    Totaro, M.G.2    Prosperini, E.3    Notarbartolo, S.4    Testa, G.5    Natoli, G.6
  • 17
    • 0033569406 scopus 로고    scopus 로고
    • Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
    • Golub TR, Slonim DK, Tamayo P, Huard C, Gaasenbeek M, Mesirov JP, et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 1999;286:531-7.
    • (1999) Science , vol.286 , pp. 531-537
    • Golub, T.R.1    Slonim, D.K.2    Tamayo, P.3    Huard, C.4    Gaasenbeek, M.5    Mesirov, J.P.6
  • 18
    • 34447119507 scopus 로고    scopus 로고
    • Spontaneousmammary tumors differ widely in their inherent sensitivity to adoptively transferred T cells
    • Wall EM, Milne K, Martin ML, Watson PH, Theiss P, Nelson BH. Spontaneousmammary tumors differ widely in their inherent sensitivity to adoptively transferred T cells. Cancer Re 2007;67:6442-50.
    • (2007) Cancer Re , vol.67 , pp. 6442-6450
    • Wall, E.M.1    Milne, K.2    Martin, M.L.3    Watson, P.H.4    Theiss, P.5    Nelson, B.H.6
  • 20
    • 0035760889 scopus 로고    scopus 로고
    • Ineffective erythropoiesis in Stat5a (-/-) 5b (-/-) mice due to decreased survival of early erythroblasts
    • Socolovsky M, Nam H, Fleming MD, Haase VH, Brugnara C, Lodish HF. Ineffective erythropoiesis in Stat5a (-/-) 5b (-/-) mice due to decreased survival of early erythroblasts. Blood 2001;98:3261-73.
    • (2001) Blood , vol.98 , pp. 3261-3273
    • Socolovsky, M.1    Nam, H.2    Fleming, M.D.3    Haase, V.H.4    Brugnara, C.5    Lodish, H.F.6
  • 21
    • 84956427297 scopus 로고
    • A direct measurement of the radiation sensitivity of normal mouse bone marrow cells
    • Till JE, McCulloch EA. A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. Radiat Res 1961;14:213-22.
    • (1961) Radiat Res , vol.14 , pp. 213-222
    • Till, J.E.1    McCulloch, E.A.2
  • 22
    • 79551519982 scopus 로고    scopus 로고
    • Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice
    • Elkabets M, Gifford AM, Scheel C, Nilsson B, Reinhardt F, Bray MA, et al. Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice. J Clin Invest 2011;121:784-99.
    • (2011) J Clin Invest , vol.121 , pp. 784-799
    • Elkabets, M.1    Gifford, A.M.2    Scheel, C.3    Nilsson, B.4    Reinhardt, F.5    Bray, M.A.6
  • 23
    • 40349094954 scopus 로고    scopus 로고
    • Inflammation and breast cancer. Balancing immune response: Crosstalk between adaptive and innate immune cells during breast cancer progression
    • DeNardo DG, Coussens LM. Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression. Breast Cancer Res 2007;9:212.
    • (2007) Breast Cancer Res , vol.9 , pp. 212
    • DeNardo, D.G.1    Coussens, L.M.2
  • 24
    • 80053401068 scopus 로고    scopus 로고
    • Breast cancer stem cells, cytokine networks, and the tumor microenvironment
    • Korkaya H, Liu S, Wicha MS. Breast cancer stem cells, cytokine networks, and the tumor microenvironment. J Clin Invest 2011;121:3804-9.
    • (2011) J Clin Invest , vol.121 , pp. 3804-3809
    • Korkaya, H.1    Liu, S.2    Wicha, M.S.3
  • 26
    • 35348849015 scopus 로고    scopus 로고
    • Hox genes in hematopoiesis and leukemogenesis
    • Argiropoulos B, Humphries RK. Hox genes in hematopoiesis and leukemogenesis. Oncogene 2007;26:6766-76.
    • (2007) Oncogene , vol.26 , pp. 6766-6776
    • Argiropoulos, B.1    Humphries, R.K.2
  • 27
    • 79251609962 scopus 로고    scopus 로고
    • Epigenetic regulations in hematopoietic Hox code
    • He H, Hua X, Yan J. Epigenetic regulations in hematopoietic Hox code. Oncogene 2011;30:379-88.
    • (2011) Oncogene , vol.30 , pp. 379-388
    • He, H.1    Hua, X.2    Yan, J.3
  • 28
    • 76549105779 scopus 로고    scopus 로고
    • MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele
    • Thiel AT, Blessington P, Zou T, Feather D, Wu X, Yan J, et al. MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele. Cancer Cell 2010;17:148-59.
    • (2010) Cancer Cell , vol.17 , pp. 148-159
    • Thiel, A.T.1    Blessington, P.2    Zou, T.3    Feather, D.4    Wu, X.5    Yan, J.6
  • 29
    • 67349266612 scopus 로고    scopus 로고
    • Haematopoietic malignancies caused by dysregulation of a chromatinbinding PHD finger
    • Wang GG, Song J, Wang Z, Dormann HL, Casadio F, Li H, et al. Haematopoietic malignancies caused by dysregulation of a chromatinbinding PHD finger. Nature 2009;459:847-51.
    • (2009) Nature , vol.459 , pp. 847-851
    • Wang, G.G.1    Song, J.2    Wang, Z.3    Dormann, H.L.4    Casadio, F.5    Li, H.6
  • 30
    • 84857195696 scopus 로고    scopus 로고
    • Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia
    • Grembecka J, He S, Shi A, Purohit T, Muntean AG, Sorenson RJ, et al. Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia. Nat Chem Biol 2012;8:277-84.
    • (2012) Nat Chem Biol , vol.8 , pp. 277-284
    • Grembecka, J.1    He, S.2    Shi, A.3    Purohit, T.4    Muntean, A.G.5    Sorenson, R.J.6
  • 31
    • 32244439095 scopus 로고    scopus 로고
    • The tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression
    • Chen YX, Yan J, Keeshan K, Tubbs AT, Wang H, Silva A, et al. The tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression. Proc Natl Acad Sci U S A 2006;103:1018-23.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 1018-1023
    • Chen, Y.X.1    Yan, J.2    Keeshan, K.3    Tubbs, A.T.4    Wang, H.5    Silva, A.6
  • 32
    • 84862147254 scopus 로고    scopus 로고
    • Oncogenic kras-induced GM-CSF production promotes the development of pancreatic neoplasia
    • Pylayeva-Gupta Y, Lee KE, Hajdu CH, Miller G, Bar-Sagi D. Oncogenic kras-induced GM-CSF production promotes the development of pancreatic neoplasia. Cancer Cell 2012;21:836-47.
    • (2012) Cancer Cell , vol.21 , pp. 836-847
    • Pylayeva-Gupta, Y.1    Lee, K.E.2    Hajdu, C.H.3    Miller, G.4    Bar-Sagi, D.5
  • 33
    • 84866784798 scopus 로고    scopus 로고
    • Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy
    • DeNardo DG, Brennan DJ, Rexhepaj E, Ruffell B, Shiao SL, Madden SF, et al. Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy. Cancer Discov 2011;1:54-67.
    • (2011) Cancer Discov , vol.1 , pp. 54-67
    • DeNardo, D.G.1    Brennan, D.J.2    Rexhepaj, E.3    Ruffell, B.4    Shiao, S.L.5    Madden, S.F.6
  • 35
    • 77953462161 scopus 로고    scopus 로고
    • Quiescent haematopoietic stem cells are activated by IFN-g in response to chronic infection
    • Baldridge MT, King KY, Boles NC, Weksberg DC, Goodell MA. Quiescent haematopoietic stem cells are activated by IFN-g in response to chronic infection. Nature 2010;465:793-7.
    • (2010) Nature , vol.465 , pp. 793-797
    • Baldridge, M.T.1    King, K.Y.2    Boles, N.C.3    Weksberg, D.C.4    Goodell, M.A.5
  • 36
    • 0026716157 scopus 로고
    • Long-term recombinant human granulocyte colony-stimulating factor (rhG-CSF) treatment severely depresses murine marrow erythropoiesis without causing an anemia
    • de Haan G, Loeffler M, Nijhof W. Long-term recombinant human granulocyte colony-stimulating factor (rhG-CSF) treatment severely depresses murine marrow erythropoiesis without causing an anemia. Exp Hematol 1992;20:600-4.
    • (1992) Exp Hematol , vol.20 , pp. 600-604
    • De Haan, G.1    Loeffler, M.2    Nijhof, W.3
  • 38
    • 0035875880 scopus 로고    scopus 로고
    • Anemia as an independent prognostic factor for survival in patients with cancer: A systemic, quantitative review
    • Caro JJ, Salas M, Ward A, Goss G. Anemia as an independent prognostic factor for survival in patients with cancer: a systemic, quantitative review. Cancer 2001;91:2214-21.
    • (2001) Cancer , vol.91 , pp. 2214-2221
    • Caro, J.J.1    Salas, M.2    Ward, A.3    Goss, G.4
  • 39
    • 33845944941 scopus 로고    scopus 로고
    • Murine mammary carcinoma 4T1 induces a leukemoid reaction with splenomegaly: Association with tumorderived growth factors
    • DuPre SA, Hunter KW Jr. Murine mammary carcinoma 4T1 induces a leukemoid reaction with splenomegaly: association with tumorderived growth factors. Exp Mol Pathol 2007;82:12-24.
    • (2007) Exp Mol Pathol , vol.82 , pp. 12-24
    • DuPre, S.A.1    Hunter Jr., K.W.2
  • 40
    • 81155131681 scopus 로고    scopus 로고
    • Tumor-derived G-CSF facilitates neoplastic growth through a granulocytic myeloidderived suppressor cell-dependent mechanism
    • Waight JD, Hu Q, Miller A, Liu S, Abrams SI. Tumor-derived G-CSF facilitates neoplastic growth through a granulocytic myeloidderived suppressor cell-dependent mechanism. PLoS One 2011;6:e27690.
    • (2011) PLoS One , vol.6
    • Waight, J.D.1    Hu, Q.2    Miller, A.3    Liu, S.4    Abrams, S.I.5
  • 41
    • 0030736703 scopus 로고    scopus 로고
    • Flt3 ligand synergizeswith granulocyte-macrophage colony-stimulating factor or granulocyte colony-stimulating factor to mobilize hematopoietic progenitor cells into the peripheral blood of mice
    • Brasel K, McKenna HJ, Charrier K, Morrissey PJ, Williams DE, Lyman SD. Flt3 ligand synergizeswith granulocyte-macrophage colony-stimulating factor or granulocyte colony-stimulating factor to mobilize hematopoietic progenitor cells into the peripheral blood of mice. Blood 1997;90:3781-8.
    • (1997) Blood , vol.90 , pp. 3781-3788
    • Brasel, K.1    McKenna, H.J.2    Charrier, K.3    Morrissey, P.J.4    Williams, D.E.5    Lyman, S.D.6
  • 42
    • 0039434927 scopus 로고    scopus 로고
    • Bladder cancer producing granulocyte colony-stimulating factor (G-CSF): A case report
    • Asano T, Morimoto S, Kitami Y, Miyauchi T, Sakai K, Takagi K. [Bladder cancer producing granulocyte colony-stimulating factor (G-CSF): a case report]. Hinyokika Kiyo 2002;48:495-8.
    • (2002) Hinyokika Kiyo , vol.48 , pp. 495-498
    • Asano, T.1    Morimoto, S.2    Kitami, Y.3    Miyauchi, T.4    Sakai, K.5    Takagi, K.6
  • 43
    • 58849161785 scopus 로고    scopus 로고
    • Urinary bladder cancer producing granulocytecolony stimulating factor: A case report and review of the literature
    • Yoshino T, Yoneda K. [Urinary bladder cancer producing granulocytecolony stimulating factor: a case report and review of the literature]. Hinyokika Kiyo 2008;54:775-8.
    • (2008) Hinyokika Kiyo , vol.54 , pp. 775-778
    • Yoshino, T.1    Yoneda, K.2
  • 45
    • 79956340285 scopus 로고    scopus 로고
    • H-Ras-specific upregulation of granulocyte colony-stimulating factor promotes human breast cell invasion via matrix metalloproteinase-2
    • Park S, Kim ES, Noh DY, Hwang KT, Moon A. H-Ras-specific upregulation of granulocyte colony-stimulating factor promotes human breast cell invasion via matrix metalloproteinase-2. Cytokine 2011;55:126-33.
    • (2011) Cytokine , vol.55 , pp. 126-133
    • Park, S.1    Kim, E.S.2    Noh, D.Y.3    Hwang, K.T.4    Moon, A.5
  • 46
    • 35948997676 scopus 로고    scopus 로고
    • The plasma levels of granulocyte-colony stimulating factor and granulocytemacrophage colony stimulating factor in breast cancer patients
    • Lawicki S, Czygier M, Omyla J, Bedkowska E, Szmitkowski M. [The plasma levels of granulocyte-colony stimulating factor and granulocytemacrophage colony stimulating factor in breast cancer patients]. Pol Merkur Lekarski 2007;23:259-63.
    • (2007) Pol Merkur Lekarski , vol.23 , pp. 259-263
    • Lawicki, S.1    Czygier, M.2    Omyla, J.3    Bedkowska, E.4    Szmitkowski, M.5
  • 47
    • 34247890015 scopus 로고    scopus 로고
    • Assessing serum cytokine profiles in breast cancer patients receiving a HER2/neu vaccine using Luminex technology
    • Dehqanzada ZA, Storrer CE, Hueman MT, Foley RJ, Harris KA, Jama YH, et al. Assessing serum cytokine profiles in breast cancer patients receiving a HER2/neu vaccine using Luminex technology. Oncol Rep 2007;17:687-94.
    • (2007) Oncol Rep , vol.17 , pp. 687-694
    • Dehqanzada, Z.A.1    Storrer, C.E.2    Hueman, M.T.3    Foley, R.J.4    Harris, K.A.5    Jama, Y.H.6
  • 49
    • 77952222310 scopus 로고    scopus 로고
    • Squamous cell carcinoma of the uterine cervix producing granulocyte colony-stimulating factor: A report of 4 cases and a review of the literature
    • Matsumoto Y, Mabuchi S, Muraji M, Morii E, Kimura T. Squamous cell carcinoma of the uterine cervix producing granulocyte colony-stimulating factor: a report of 4 cases and a review of the literature. Int J Gynecol Cancer 2010;20:417-21.
    • (2010) Int J Gynecol Cancer , vol.20 , pp. 417-421
    • Matsumoto, Y.1    Mabuchi, S.2    Muraji, M.3    Morii, E.4    Kimura, T.5
  • 50
    • 0036090290 scopus 로고    scopus 로고
    • Overexpression of themyeloid leukemia-associated Hoxa9 gene in bone marrow cells induces stem cell expansion
    • Thorsteinsdottir U, Mamo A, Kroon E, Jerome L, Bijl J, Lawrence HJ, et al. Overexpression of themyeloid leukemia-associated Hoxa9 gene in bone marrow cells induces stem cell expansion. Blood 2002;99:121-9.
    • (2002) Blood , vol.99 , pp. 121-129
    • Thorsteinsdottir, U.1    Mamo, A.2    Kroon, E.3    Jerome, L.4    Bijl, J.5    Lawrence, H.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.