The tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 4, 2006, Pages 1018-1023

  Chen, Ya Xiong ^a   Yan, Jizhou ^a   Keeshan, Karen ^a,c   Tubbs, Anthony T ^a   Wang, Haoren ^a   Silva, Albert ^a   Brown, Eric J ^a   Hess, Jay L ^b,d   Pear, Warren S ^a,b,c   Hua, Xianxin ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c BRB2/3   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Histone lysine methylation; Men1 gene; Mixed lineage leukemia; Multiple endocrine neoplasia type 1

Indexed keywords

METHIONINE; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CELL TRANSFORMATION; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE LOCUS; GENE MUTATION; HEMATOPOIESIS; HOX GENE; KNOCKOUT MOUSE; LEUKOCYTE COUNT; MOUSE; MULTIPLE ENDOCRINE NEOPLASIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANIMALS; BLOTTING, WESTERN; CELL LINE, TRANSFORMED; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; DNA; DNA METHYLATION; DNA-BINDING PROTEINS; EXONS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENOTYPE; HEMATOPOIESIS; HISTONES; HOMEODOMAIN PROTEINS; HOMOZYGOTE; LEUKEMIA; LYSINE; METHYLATION; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MODELS, GENETIC; MODELS, STATISTICAL; MYELOID CELLS; PROTO-ONCOGENE PROTEINS; RETROVIRIDAE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STEM CELLS; TIME FACTORS; TRANSGENES;

ANIMALIA;

EID: 32244439095     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0510347103     Document Type: Article

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