The role of sorption promoters in increasing the bioavailability of drugs in oral preparations
Sharma P, Chawla HPS, Panchagnula R. The role of sorption promoters in increasing the bioavailability of drugs in oral preparations. Drugs Future 1999;24:1221.
Payghan SA, Bhat M, Savla A, Toppo E, Purohit S. Solubility of active pharmaceutical ingredients (API) has always been a concern for formulators, since inadequate aqueous solubility may hamper development of parenteral products and limit bioavailability of oral products., on-line, .
Relationship between lipophilicity of BCS class III and IV drugs and the functional activity of peroral absorption enhancers
Sharma P, Varma MVS, Chawla HPS, Panchagnula R. Relationship between lipophilicity of BCS class III and IV drugs and the functional activity of peroral absorption enhancers. Farmaco 2005;60:870.
Novel oral colon-specific drug delivery systems for pharmacotherapy of peptide and nonpeptide drugs
Reddy SM, Sinha VR, Reddy DS. Novel oral colon-specific drug delivery systems for pharmacotherapy of peptide and nonpeptide drugs. Drugs Today 1999;35:537.
Improvement of intestinal peptide absorption by a synthetic bile acid derivative, cholylsarcosine
Michael S, Thole M, Dillmann R, Fahr A, Drewe J, Fricker G. Improvement of intestinal peptide absorption by a synthetic bile acid derivative, cholylsarcosine. Eur J Pharm Sci 2000;10:133.
Comparison of pharmacokinetic and pharmacodynamic properties of single-dose oral insulin spray and subcutaneous insulin injection in healthy subjects using the euglycemic clamp technique
Cernea S, Kidron M, Wohlgelernter J, Modi P, Raz I. Comparison of pharmacokinetic and pharmacodynamic properties of single-dose oral insulin spray and subcutaneous insulin injection in healthy subjects using the euglycemic clamp technique. Clin Ther 2004;26:2084.
Pharmacology of bile acids and their derivatives: Absorption promoters and therapeutic agents
Mikov M, Fawcett JP, Kuhajda K, Kevresan S. Pharmacology of bile acids and their derivatives: absorption promoters and therapeutic agents. Eur J Drug Metab Pharmacokinet 2006;31:237.
Absorption study of deoxycholic acid-heparin conjugate as a new form of oral anti-coagulant
Kim SK, Lee DY, Lee E, Lee YK, Kim CY, Moon HT, Byun Y. Absorption study of deoxycholic acid-heparin conjugate as a new form of oral anti-coagulant. J Control Release 2007;120:4.
The influence of 3alpha,7alpha-dihydroxy-12-keto-5beta-cholanate on gliclazide pharmacokinetics and glucose levels in a rat model of diabetes
Mikov M, Al-Salami H, Golocorbin-Kon S, Skrbic R, Raskovic A, Fawcett JP. The influence of 3alpha,7alpha-dihydroxy-12-keto-5beta-cholanate on gliclazide pharmacokinetics and glucose levels in a rat model of diabetes. Eur J Drug Metab Pharmacokinet 2008;33:137.
Effect of bile salts on the transport of morphine-6-glucuronide in rat brain endothelial cells
Yang L, Zhang H, Fawcett JP, Mikov M, Tucker IG. Effect of bile salts on the transport of morphine-6-glucuronide in rat brain endothelial cells. J Pharm Sci 2011;100:1516.
Mechanistic studies of the effect of bile salts on rhodamine 123 uptake into RBE4 cells
Yang L, Fawcett JP, Ostergaard J, Zhang H, Tucker IG. Mechanistic studies of the effect of bile salts on rhodamine 123 uptake into RBE4 cells. Mol Pharm 2012;9:29.
Bile acids as enhancers of steroid penetration through excised hairless mouse skin
Carelli V, Di Colo G, Nannipieri E, Serafini MF. Bile acids as enhancers of steroid penetration through excised hairless mouse skin. Int J Pharm 1993;89:81.
Effect of cholic acid and its keto derivatives on the analgesic action of lidocaine and associated biochemical parameters in rats
Posa M, Kevresan S, Mikov M, Cirin-Novta V, Kuhajda K. Effect of cholic acid and its keto derivatives on the analgesic action of lidocaine and associated biochemical parameters in rats. Eur J Drug Metab Pharmacokinet 2007;32:109.
Physicochemical properties of bile acids and their relationship to biological properties: An overview of the problem
Hofmann AF, Roda A. Physicochemical properties of bile acids and their relationship to biological properties: an overview of the problem. J Lipid Res 1984;25:1477.
New cationic surfactants derived from bile acids: Synthesis and thermodynamic and biophysicochemical properties such as membrane perturbation and protein solubilizing abilities
Araki YI, Lee S, Sugihara G, Furuichi M, Yamashita S, Ohseto F. New cationic surfactants derived from bile acids: synthesis and thermodynamic and biophysicochemical properties such as membrane perturbation and protein solubilizing abilities. Colloid Surf B 1996;8:81.
A novel class of organogelator based on n-isopropylcholamide and the first observation of fibrous colloidal aggregates
Hishikawa Y, Sada K, Watanbe R, Miyata M, Hanabusa K. A novel class of organogelator based on n-isopropylcholamide and the first observation of fibrous colloidal aggregates. Chem Lett 1998;1998:795.
Metal coordination as a tool for controlling the self-assembling and gelation properties of novel type cholic amide-phenanthroline gelating agent
Dukh M, Saman D, Kroulik J, Cerny I, Pouzar V, Kral V, Drasar P. Metal coordination as a tool for controlling the self-assembling and gelation properties of novel type cholic amide-phenanthroline gelating agent. Tetrahedron 2003;59:4069.
Structure and dynamics of cholic acid and dodecylphosphocholine-cholic acid aggregates
Sayyed-Ahmad A, Lichtenberger LM, Gorfe AA. Structure and dynamics of cholic acid and dodecylphosphocholine-cholic acid aggregates. Langmuir 2010;26:13407.
Investigation of new acyloxy derivatives of cholic acid and their esters as drug absorption modifiers
Mrozek L, Dvorakova L, Mandelova Z, Rarova L, Rezacova A, Placek L, Opatrilova R, Dohnal J, Paleta O, Kral V, Drasar P, Jampilek J. Investigation of new acyloxy derivatives of cholic acid and their esters as drug absorption modifiers. Steroids 2011;76:1082.
New propanoyloxy derivatives of 5bcholan-24-oic acid as drug absorption modifiers
Coufalova L, Mrozek L, Rarova L, Placek L, Opatrilova R, Dohnal J, Kralova K., Paleta, O, Kral V, Drasar P, Jampilek J. New propanoyloxy derivatives of 5bcholan-24-oic acid as drug absorption modifiers. Steroids 2013;78:435.
Synthesis, physicochemical properties and penetration activity of alkyl-6-(2,5-dioxopyrrolidin-1-yl)-2-(2-oxopyrrolidin-1-yl)hexanoates as potential transdermal penetration enhancers
Brychtova K, Jampilek J, Opatrilova R, Raich I, Csollei J. Synthesis, physicochemical properties and penetration activity of alkyl-6-(2,5- dioxopyrrolidin-1-yl)-2-(2-oxopyrrolidin-1-yl)hexanoates as potential transdermal penetration enhancers. Bioorg Med Chem 2010;18:73.
Physicochemical high throughput screening: Parallel artificial membrane permeation assay in the description of passive absorption processes
Kansy M, Senner F, Gubernator K. Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes. J Med Chem 1998;41:1007.
PAMPA-A drug absorption in vitro model 13. Chemical selectivity due to membrane hydrogen bonding: In combo comparisons of HDM-, DOPC-, and DS-PAMPA models
Avdeef A, Tsinman O. PAMPA-a drug absorption in vitro model 13. Chemical selectivity due to membrane hydrogen bonding: In combo comparisons of HDM-, DOPC-, and DS-PAMPA models. Eur J Pharm Sci 2006;28:43.
The importance of and different approaches to permeability determination
Mandic Z, editor, Zagreb: IAPC Publishing
Tam KY, Velicky M, Dryfe RAW. The importance of and different approaches to permeability determination. In: Mandic Z, editor. Physico-chemical methods in drug discovery and development. Zagreb: IAPC Publishing; 2012. p. 121-64.
Estimation of lipophilicity by reversed-phase thin-layer chromatography
Pliska V, Testa B, van de Waterbeemd H, editors, Weinheim: VCH
Mannhold R, Dross K, Sonntag C. Estimation of lipophilicity by reversed-phase thin-layer chromatography. In: Pliska V, Testa B, van de Waterbeemd H, editors. Lipophilicity in drug action and toxicology. Weinheim: VCH; 1996. p. 141-56.
Fragmental methods in the analysis of biological activities of diverse compound sets
Japertas P, Didziapetris R, Petrauskas A. Fragmental methods in the analysis of biological activities of diverse compound sets. Mini-Rev Med Chem 2003;3:797-808.
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
Lipinski C A, Lombardo F, Dominy BW, Feeney PJ. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Deliv Rev 1997; 23:3.
Estimation of the effect of NaCl on the solubility of organic compounds in aqueous solutions
Ni N, El-Sayed MM, Sanghvi T, Yalkowsky SH. Estimation of the effect of NaCl on the solubility of organic compounds in aqueous solutions. J Pharm Sci 2000;89:1620.
Rapid colorimetric screening of drug interaction and penetration through lipid barriers
Katz M, Ben-Shlush I, Kolusheva S, Jelinek R. Rapid colorimetric screening of drug interaction and penetration through lipid barriers. Pharm Res 2006;23:580.
Development and evaluation of the essential oil from Magnolia fargesii for enhancing the transdermal absorption of theophylline and cianidanol
Fang JY, Tsai TH, Hung CF, Wong WW. Development and evaluation of the essential oil from Magnolia fargesii for enhancing the transdermal absorption of theophylline and cianidanol. J Pharm Pharmacol 2004;56:1493.
Transdermal delivery of theophylline from alcohol vehicles
Sloan KB, Beall HD, Taylor HE, Getz JJ, Villaneuva R, Nipper R, Smith K. Transdermal delivery of theophylline from alcohol vehicles. Int J Pharm 1998;171:185.
A new colorimetric assay for studying and rapid screening of membrane penetration enhancers
Evrard D, Touitou E, Kolusheva S, Fishov Y, Jelinek R. A new colorimetric assay for studying and rapid screening of membrane penetration enhancers. Pharm Res 2001;18:943.
Terpene penetration enhancers in propylene glycol/water co-solvent systems: Effectiveness and mechanism of action
Yamane MA, Williams AC, Barry BW. Terpene penetration enhancers in propylene glycol/water co-solvent systems: effectiveness and mechanism of action. J Pharm Pharmacol 1995;47:978.
Porcine ear skin: An in vitro model for human skin
Jacobi U, Kaiser M, Toll R, Mangelsdorf S, Audring H, Otberg N, Sterry W, Lademann J. Porcine ear skin: an in vitro model for human skin. Skin Res Technol 2007;13:19.
Pig ear skin ex vivo as a model for in vivo dermatopharmacokinetic studies in man
Herkenne C, Naik A, Kalia YN, Hadgraft J, Guy RH. Pig ear skin ex vivo as a model for in vivo dermatopharmacokinetic studies in man. Pharm Res 2006;23:1850.
The skin of domestic mammals as a model for the human skin, with special reference to the domestic pig
Meyer W, Schwarz K, Neurand KT. The skin of domestic mammals as a model for the human skin, with special reference to the domestic pig. Curr Probl Dermatol 1978;7:39.
Interactions of skin thickness and physicochemical properties of test compounds in percutaneous penetration studies
Wilkinson SC, Maas WJM, Nielsen JB, Greaves LC, Sandt JJM, Williams FM. Interactions of skin thickness and physicochemical properties of test compounds in percutaneous penetration studies. Int Arch Occup Environ Health 2006;79:405.
Molecular modeling of skin permeation enhancement by chemical agents
Walters KA, Hadgraft J, editors, New York: Marcel Dekker
Brain KR, Walters KA. Molecular modeling of skin permeation enhancement by chemical agents. In: Walters KA, Hadgraft J, editors. Pharmaceutical skin penetration enhancement. New York: Marcel Dekker; 1993. p. 389-416.
Investigations on the mechanism of aqueous solubility increase caused by some hydrotropes
Da Silva RC, Spitzer M, Da Silva LHM, Loh W. Investigations on the mechanism of aqueous solubility increase caused by some hydrotropes. Thermochim Acta 1999;328:161.
Cut-off effect in antimicrobial activity and in membrane perturbation efficiency of the homologous series of N, N-dimethylalkylamine oxides
Devinsky F, Kopecka-Leitmanova A, Sersen F, Balgavy P. Cut-off effect in antimicrobial activity and in membrane perturbation efficiency of the homologous series of N, N-dimethylalkylamine oxides. J Pharm Pharmacol 1990;42:790.
