메뉴 건너뛰기




Volumn 100, Issue 4, 2011, Pages 1516-1524

Effect of bile salts on the transport of morphine-6-glucuronide in rat brain endothelial cells

Author keywords

Astrocyte; Bile salt; Blood brain barrier; M6G; Permeability; RBE4 cell; Transport

Indexed keywords

12 MONOKETOCHOLATE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BILE SALT; CHOLIC ACID; DEOXYCHOLIC ACID; MORPHINE 6 GLUCURONIDE; SUCROSE; TAUROCHOLIC ACID; UNCLASSIFIED DRUG; BILE ACID; DRUG VEHICLE; MORPHINE DERIVATIVE; MORPHINE-6-GLUCURONIDE;

EID: 79951930856     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22390     Document Type: Article
Times cited : (23)

References (46)
  • 1
    • 27744448891 scopus 로고    scopus 로고
    • Absorption enhancement, mechanistic and toxicity studies of medium chain fatty acids, cyclodextrins and bile salts as peroral absorption enhancers
    • Sharma P, Varma MV, Chawla HP, Panchagnula R. 2005. Absorption enhancement, mechanistic and toxicity studies of medium chain fatty acids, cyclodextrins and bile salts as peroral absorption enhancers. Farmaco 60(11-12):884-893.
    • (2005) Farmaco , vol.60 , Issue.11-12 , pp. 884-893
    • Sharma, P.1    Varma, M.V.2    Chawla, H.P.3    Panchagnula, R.4
  • 3
    • 0030604042 scopus 로고    scopus 로고
    • Evaluation of ocular permeation enhancers: In vitro effects on corneal transport of four β-blockers, and in vitro/in vivo toxic activity
    • Saettone MF, Chetoni P, Cerbai R, Mazzanti G, Braghiroli L. 1996. Evaluation of ocular permeation enhancers: In vitro effects on corneal transport of four β-blockers, and in vitro/in vivo toxic activity. Int J Pharm 142(1):103-113.
    • (1996) Int J Pharm , vol.142 , Issue.1 , pp. 103-113
    • Saettone, M.F.1    Chetoni, P.2    Cerbai, R.3    Mazzanti, G.4    Braghiroli, L.5
  • 4
    • 3542993842 scopus 로고    scopus 로고
    • 3Alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate as blood-brain barrier permeator
    • Mikov M, Kevresan S, Kuhajda K, Jakovljevic V, Vasovic V. 2004. 3Alpha, 7alpha-dihydroxy-12-oxo-5beta-cholanate as blood-brain barrier permeator. Pol J Pharmacol 56(3):367-371.
    • (2004) Pol J Pharmacol , vol.56 , Issue.3 , pp. 367-371
    • Mikov, M.1    Kevresan, S.2    Kuhajda, K.3    Jakovljevic, V.4    Vasovic, V.5
  • 5
    • 0016590983 scopus 로고
    • Diagnostic value of serum bile acid estimations in liver disease
    • Barnes S, Gallo GA, Trash DB, Morris JS. 1975. Diagnostic value of serum bile acid estimations in liver disease. J Clin Pathol 28(6):506-509.
    • (1975) J Clin Pathol , vol.28 , Issue.6 , pp. 506-509
    • Barnes, S.1    Gallo, G.A.2    Trash, D.B.3    Morris, J.S.4
  • 6
    • 0026072540 scopus 로고
    • Synergistic effect of bile acid, endotoxin, and ammonia on brain edema
    • Tominaga S, Watanabe A, Tsuji T. 1991. Synergistic effect of bile acid, endotoxin, and ammonia on brain edema. Metab Brain Dis 6(2):93-105.
    • (1991) Metab Brain Dis , vol.6 , Issue.2 , pp. 93-105
    • Tominaga, S.1    Watanabe, A.2    Tsuji, T.3
  • 7
    • 0035156232 scopus 로고    scopus 로고
    • Progress and limitations in the use of in vitro cell cultures to serve as a permeability screen for the blood-brain barrier
    • Gumbleton M, Audus KL. 2001. Progress and limitations in the use of in vitro cell cultures to serve as a permeability screen for the blood-brain barrier. J Pharm Sci 90(11):1681-1698.
    • (2001) J Pharm Sci , vol.90 , Issue.11 , pp. 1681-1698
    • Gumbleton, M.1    Audus, K.L.2
  • 8
    • 34249048897 scopus 로고    scopus 로고
    • Characteristics of the ATP-induced Ca2+-entry pathway in the t-BBEC 117 cell line derived from bovine brain endothelial cells
    • Yamazaki D, Ohya S, Asai K, Imaizumi Y. 2007. Characteristics of the ATP-induced Ca2+-entry pathway in the t-BBEC 117 cell line derived from bovine brain endothelial cells. J Pharmacol Sci 104(1):103-107.
    • (2007) J Pharmacol Sci , vol.104 , Issue.1 , pp. 103-107
    • Yamazaki, D.1    Ohya, S.2    Asai, K.3    Imaizumi, Y.4
  • 10
    • 0032934648 scopus 로고    scopus 로고
    • High-affinity efflux transport system for glutathione conjugates on the luminal membrane of a mouse brain capillary endothelial cell line (MBEC4)
    • Homma M, Suzuki H, Kusuhara H, Naito M, Tsuruo T, Sugiyama Y. 1999. High-affinity efflux transport system for glutathione conjugates on the luminal membrane of a mouse brain capillary endothelial cell line (MBEC4). J Pharmacol Exp Ther 288(1):198-203.
    • (1999) J Pharmacol Exp Ther , vol.288 , Issue.1 , pp. 198-203
    • Homma, M.1    Suzuki, H.2    Kusuhara, H.3    Naito, M.4    Tsuruo, T.5    Sugiyama, Y.6
  • 12
    • 0028024646 scopus 로고
    • Regulation of gamma-glutamyl transpeptidase and alkaline phosphatase activities in immortalized rat brain microvessel endothelial cells
    • Roux F, Durieu-Trautmann O, Chaverot N, Claire M, Mailly P, Bourre JM, Strosberg AD, Couraud PO. 1994. Regulation of gamma-glutamyl transpeptidase and alkaline phosphatase activities in immortalized rat brain microvessel endothelial cells. J Cell Physiol 159(1):101-113.
    • (1994) J Cell Physiol , vol.159 , Issue.1 , pp. 101-113
    • Roux, F.1    Durieu-Trautmann, O.2    Chaverot, N.3    Claire, M.4    Mailly, P.5    Bourre, J.M.6    Strosberg, A.D.7    Couraud, P.O.8
  • 14
    • 0035900881 scopus 로고    scopus 로고
    • Transendothelial permeability of chlorpyrifos in RBE4 monolayers is modulated by astrocyte-conditioned medium
    • Yang J, Mutkus LA, Sumner D, Stevens JT, Eldridge JC, Strandhoy JW, Aschner M. 2001. Transendothelial permeability of chlorpyrifos in RBE4 monolayers is modulated by astrocyte-conditioned medium. Mol Brain Res 97(1):43-50.
    • (2001) Mol Brain Res , vol.97 , Issue.1 , pp. 43-50
    • Yang, J.1    Mutkus, L.A.2    Sumner, D.3    Stevens, J.T.4    Eldridge, J.C.5    Strandhoy, J.W.6    Aschner, M.7
  • 15
    • 0030748912 scopus 로고    scopus 로고
    • F-actin cytoskeleton and sucrose permeability of immortalised rat brain microvascular endothelial cell monolayers: Effects of cyclic AMP and astrocytic factors
    • Rist RJ, Romero IA, Chan MWK, Couraud PO, Roux F, Abbott NJ. 1997. F-actin cytoskeleton and sucrose permeability of immortalised rat brain microvascular endothelial cell monolayers: Effects of cyclic AMP and astrocytic factors. Brain Res 768(1-2):10-18.
    • (1997) Brain Res , vol.768 , Issue.1-2 , pp. 10-18
    • Rist, R.J.1    Romero, I.A.2    Chan, M.W.K.3    Couraud, P.O.4    Roux, F.5    Abbott, N.J.6
  • 16
    • 33750605004 scopus 로고    scopus 로고
    • Blood-brain barrier and cell-cell interactions: Methods for establishing in vitro models of the blood-brain barrier and transport measurements
    • Aschner M, Fitsanakis VA, dos Santos AP, Olivi L, Bressler JP. 2006. Blood-brain barrier and cell-cell interactions: Methods for establishing in vitro models of the blood-brain barrier and transport measurements. Methods Mol Biol 341:1-15.
    • (2006) Methods Mol Biol , vol.341 , pp. 1-15
    • Aschner, M.1    Fitsanakis, V.A.2    dos Santos, A.P.3    Olivi, L.4    Bressler, J.P.5
  • 17
    • 33646088705 scopus 로고    scopus 로고
    • Puromycin-purified rat brain microvascular endothelial cell cultures exhibit improved barrier properties in response to glucocorticoid induction
    • Calabria AR, Weidenfeller C, Jones AR, de Vries HE, Shusta EV. 2006. Puromycin-purified rat brain microvascular endothelial cell cultures exhibit improved barrier properties in response to glucocorticoid induction. J Neurochem 97(4):922-933.
    • (2006) J Neurochem , vol.97 , Issue.4 , pp. 922-933
    • Calabria, A.R.1    Weidenfeller, C.2    Jones, A.R.3    de Vries, H.E.4    Shusta, E.V.5
  • 18
    • 44349150865 scopus 로고    scopus 로고
    • Glucocorticoids increase VE-cadherin expression and cause cytoskeletal rearrangements in murine brain endothelial cEND cells
    • Blecharz KG, Drenckhahn D, Förster CY. 2008. Glucocorticoids increase VE-cadherin expression and cause cytoskeletal rearrangements in murine brain endothelial cEND cells. J Cereb Blood Flow Metab 28(6):1139-1149.
    • (2008) J Cereb Blood Flow Metab , vol.28 , Issue.6 , pp. 1139-1149
    • Blecharz, K.G.1    Drenckhahn, D.2    Förster, C.Y.3
  • 19
    • 28444454959 scopus 로고    scopus 로고
    • Influence of hydrocortisone on the mechanical properties of the cerebral endothelium in vitro
    • Schrot S, Weidenfeller C, Schäffer TE, Robenek H, Galla HJ. 2005. Influence of hydrocortisone on the mechanical properties of the cerebral endothelium in vitro. Biophys J 89(6):3904-3910.
    • (2005) Biophys J , vol.89 , Issue.6 , pp. 3904-3910
    • Schrot, S.1    Weidenfeller, C.2    Schäffer, T.E.3    Robenek, H.4    Galla, H.J.5
  • 20
    • 24144470762 scopus 로고    scopus 로고
    • Morphine-6-glucuronide: Actions and mechanisms
    • Kilpatrick GJ, Smith TW. 2005. Morphine-6-glucuronide: Actions and mechanisms. Med Res Rev 25(5):521-544.
    • (2005) Med Res Rev , vol.25 , Issue.5 , pp. 521-544
    • Kilpatrick, G.J.1    Smith, T.W.2
  • 21
    • 0019313317 scopus 로고
    • Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue
    • McCarthy KD, de Vellis J. 1980. Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J Cell Biol 85(3):890-902.
    • (1980) J Cell Biol , vol.85 , Issue.3 , pp. 890-902
    • McCarthy, K.D.1    de Vellis, J.2
  • 22
    • 0015447985 scopus 로고
    • Growth and cultivation of dissociated neurons and glial cells from embryonic chick, rat and human brain in flask cultures
    • Booher J, Sensenbrenner M. 1972. Growth and cultivation of dissociated neurons and glial cells from embryonic chick, rat and human brain in flask cultures. Neurobiology 2(3):97-105.
    • (1972) Neurobiology , vol.2 , Issue.3 , pp. 97-105
    • Booher, J.1    Sensenbrenner, M.2
  • 23
    • 0030957316 scopus 로고    scopus 로고
    • Concentration-effect relationships of morphine and morphine-6β-glucuronide in the rat
    • van Crugten JT, Somogyi AA, Nation RL, Reynolds G. 1997. Concentration-effect relationships of morphine and morphine-6β-glucuronide in the rat. Clin Exp Pharmacol Physiol 24(5):359-364.
    • (1997) Clin Exp Pharmacol Physiol , vol.24 , Issue.5 , pp. 359-364
    • van Crugten, J.T.1    Somogyi, A.A.2    Nation, R.L.3    Reynolds, G.4
  • 24
    • 0032724187 scopus 로고    scopus 로고
    • Elevated concentrations of morphine 6-beta-d-glucuronide in brain extracellular fluid despite low blood-brain barrier permeability
    • Stain-Texier F, Boschi G, Sandouk P, Scherrmann JM. 1999. Elevated concentrations of morphine 6-beta-d-glucuronide in brain extracellular fluid despite low blood-brain barrier permeability. Br J Pharmacol 128(4):917-924.
    • (1999) Br J Pharmacol , vol.128 , Issue.4 , pp. 917-924
    • Stain-Texier, F.1    Boschi, G.2    Sandouk, P.3    Scherrmann, J.M.4
  • 25
    • 64649093413 scopus 로고    scopus 로고
    • Physicochemical and biological characterization of monoketocholic acid, a novel permeability enhancer
    • Yang L, Zhang H, Mikov M, Tucker IG. 2009. Physicochemical and biological characterization of monoketocholic acid, a novel permeability enhancer. Mol Pharm 6(2):448-456.
    • (2009) Mol Pharm , vol.6 , Issue.2 , pp. 448-456
    • Yang, L.1    Zhang, H.2    Mikov, M.3    Tucker, I.G.4
  • 26
    • 29244463365 scopus 로고    scopus 로고
    • Astrocyte-endothelial interactions at the blood-brain barrier
    • Abbott NJ, Rönnbäck L, Hansson E. 2006. Astrocyte-endothelial interactions at the blood-brain barrier. Nat Rev Neurosci 7(1):41-53.
    • (2006) Nat Rev Neurosci , vol.7 , Issue.1 , pp. 41-53
    • Abbott, N.J.1    Rönnbäck, L.2    Hansson, E.3
  • 27
    • 0023471290 scopus 로고
    • Astrocyte-mediated induction of tight junctions in brain capillary endothelium: An efficient in vitro model
    • Arthur FE, Shivers RR, Bowman PD. 1987. Astrocyte-mediated induction of tight junctions in brain capillary endothelium: An efficient in vitro model. Brain Res 433(1):155-159.
    • (1987) Brain Res , vol.433 , Issue.1 , pp. 155-159
    • Arthur, F.E.1    Shivers, R.R.2    Bowman, P.D.3
  • 29
    • 0033673170 scopus 로고    scopus 로고
    • Establishment and functional characterization of an in vitro model of the blood-brain barrier, comprising a co-culture of brain capillary endothelial cells and astrocytes
    • Gaillard PJ, Voorwinden LH, Nielsen JL, Ivanov A, Atsumi R, Engman H, Ringbom C, de Boer AG, Breimer DD. 2000. Establishment and functional characterization of an in vitro model of the blood-brain barrier, comprising a co-culture of brain capillary endothelial cells and astrocytes. Eur J Pharm Sci 12(3):215-222.
    • (2000) Eur J Pharm Sci , vol.12 , Issue.3 , pp. 215-222
    • Gaillard, P.J.1    Voorwinden, L.H.2    Nielsen, J.L.3    Ivanov, A.4    Atsumi, R.5    Engman, H.6    Ringbom, C.7    de Boer, A.G.8    Breimer, D.D.9
  • 30
    • 0030748912 scopus 로고    scopus 로고
    • F-Actin cytoskeleton and sucrose permeability of immortalised rat brain microvascular endothelial cell monolayers: Effects of cyclic AMP and astrocytic factors
    • Rist RJ, Romero IA, Chan MWK, Couraud PO, Roux F, Abbott NJ. 1997. F-Actin cytoskeleton and sucrose permeability of immortalised rat brain microvascular endothelial cell monolayers: Effects of cyclic AMP and astrocytic factors. Brain Res 768(1-2):10-18.
    • (1997) Brain Res , vol.768 , Issue.1-2 , pp. 10-18
    • Rist, R.J.1    Romero, I.A.2    Chan, M.W.K.3    Couraud, P.O.4    Roux, F.5    Abbott, N.J.6
  • 31
    • 79951924969 scopus 로고    scopus 로고
    • Blood-brain barrier: Drug delivery and brain pathology
    • 1st ed. New York: Kluwer Academic Publishers.
    • David Kobiler SL, Shlomo Shapira. 2001. Blood-brain barrier: Drug delivery and brain pathology. 1st ed. New York: Kluwer Academic Publishers.
    • (2001)
    • David Kobiler, S.L.1    Shlomo, S.2
  • 32
    • 0025329190 scopus 로고
    • Comparison of in vitro and in vivo models of drug transcytosis through the blood-brain barrier
    • Pardridge WM, Triguero D, Yang J, Cancilla PA. 1990. Comparison of in vitro and in vivo models of drug transcytosis through the blood-brain barrier. J Pharmacol Exp Ther 253(2):884-891.
    • (1990) J Pharmacol Exp Ther , vol.253 , Issue.2 , pp. 884-891
    • Pardridge, W.M.1    Triguero, D.2    Yang, J.3    Cancilla, P.A.4
  • 33
    • 0019124032 scopus 로고
    • Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability
    • Levin VA. 1980. Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability. J Med Chem 23(6):682-684.
    • (1980) J Med Chem , vol.23 , Issue.6 , pp. 682-684
    • Levin, V.A.1
  • 34
    • 0018237164 scopus 로고
    • Lower limits of cerebrovascular permeability to nonelectrolytes in the conscious rat
    • Ohno K, Pettigrew KD, Rapoport SI. 1978. Lower limits of cerebrovascular permeability to nonelectrolytes in the conscious rat. Am J Physiol Heart Circ Physiol 4(3):H299-H307.
    • (1978) Am J Physiol Heart Circ Physiol , vol.4 , Issue.3
    • Ohno, K.1    Pettigrew, K.D.2    Rapoport, S.I.3
  • 36
    • 20444462366 scopus 로고    scopus 로고
    • Pericyte abundance affects sucrose permeability in cultures of rat brain microvascular endothelial cells
    • Parkinson FE, Hacking C. 2005. Pericyte abundance affects sucrose permeability in cultures of rat brain microvascular endothelial cells. Brain Res 1049(1):8-14.
    • (2005) Brain Res , vol.1049 , Issue.1 , pp. 8-14
    • Parkinson, F.E.1    Hacking, C.2
  • 37
    • 0035286778 scopus 로고    scopus 로고
    • Caco-2 monolayers in experimental and theoretical predictions of drug transport
    • Artursson P, Palm K, Luthman K. 2001. Caco-2 monolayers in experimental and theoretical predictions of drug transport. Adv Drug Delivery Rev 46(1-3):27-43.
    • (2001) Adv Drug Delivery Rev , vol.46 , Issue.1-3 , pp. 27-43
    • Artursson, P.1    Palm, K.2    Luthman, K.3
  • 38
    • 0035292828 scopus 로고    scopus 로고
    • Delivery of peptides and proteins through the blood-brain barrier
    • Bickel U, Yoshikawa T, Pardridge WM. 2001. Delivery of peptides and proteins through the blood-brain barrier. Adv Drug Deliv Rev 46(1-3):247-279.
    • (2001) Adv Drug Deliv Rev , vol.46 , Issue.1-3 , pp. 247-279
    • Bickel, U.1    Yoshikawa, T.2    Pardridge, W.M.3
  • 39
    • 0004844581 scopus 로고    scopus 로고
    • Blood-brain barrier permeability to morphine-6-glucuronide is markedly reduced compared with morphine
    • Wu D, Kang YS, Bickel U, Pardridge WM. 1997. Blood-brain barrier permeability to morphine-6-glucuronide is markedly reduced compared with morphine. Drug Metab Dispos 25(6):768-771.
    • (1997) Drug Metab Dispos , vol.25 , Issue.6 , pp. 768-771
    • Wu, D.1    Kang, Y.S.2    Bickel, U.3    Pardridge, W.M.4
  • 40
    • 0141432124 scopus 로고    scopus 로고
    • Evidence for an active transport of morphine-6-beta-d-glucuronide but not P-glycoprotein-mediated at the blood-brain barrier
    • Bourasset F, Cisternino S, Temsamani J, Scherrmann JM. 2003. Evidence for an active transport of morphine-6-beta-d-glucuronide but not P-glycoprotein-mediated at the blood-brain barrier. J Neurochem 86(6):1564-1567.
    • (2003) J Neurochem , vol.86 , Issue.6 , pp. 1564-1567
    • Bourasset, F.1    Cisternino, S.2    Temsamani, J.3    Scherrmann, J.M.4
  • 41
    • 0037199658 scopus 로고    scopus 로고
    • The influence of inhibition of probenecid sensitive transporters on the central nervous system (CNS) uptake and the antinociceptive activity of morphine-6-glucuronide in rats
    • Lötsch J, Schmidt R, Vetter G, Schmidt H, Skarke C, Niederberger E, Geisslinger G, Tegeder I. 2002. The influence of inhibition of probenecid sensitive transporters on the central nervous system (CNS) uptake and the antinociceptive activity of morphine-6-glucuronide in rats. Neurosci Lett 329(2):145-148.
    • (2002) Neurosci Lett , vol.329 , Issue.2 , pp. 145-148
    • Lötsch, J.1    Schmidt, R.2    Vetter, G.3    Schmidt, H.4    Skarke, C.5    Niederberger, E.6    Geisslinger, G.7    Tegeder, I.8
  • 42
    • 0034608103 scopus 로고    scopus 로고
    • Antinociceptive effects of morphine-6-glucuronide in homozygous MDR1a P-glycoprotein knockout and in wildtype mice in the hotplate test
    • Lötsch J, Tegeder I, Angst MS, Geisslinger G. 2000. Antinociceptive effects of morphine-6-glucuronide in homozygous MDR1a P-glycoprotein knockout and in wildtype mice in the hotplate test. Life Sci 66(24):2393-2403.
    • (2000) Life Sci , vol.66 , Issue.24 , pp. 2393-2403
    • Lötsch, J.1    Tegeder, I.2    Angst, M.S.3    Geisslinger, G.4
  • 43
    • 0036605677 scopus 로고    scopus 로고
    • Functional expression and localization of P-glycoprotein at the blood-brain barrier
    • Reina B, Gloria L, Moise B. 2002. Functional expression and localization of P-glycoprotein at the blood-brain barrier. Microsc Res Tech 57(5):365-380.
    • (2002) Microsc Res Tech , vol.57 , Issue.5 , pp. 365-380
    • Reina, B.1    Gloria, L.2    Moise, B.3
  • 44
    • 0026636390 scopus 로고
    • Comparative hepatotoxicity of cholic acid, deoxycholic acid and lithocholic acid in the rat: In vivo and in vitro studies
    • Delzenne NM, Calderon PB, Taper HS, Roberfroid MB. 1992. Comparative hepatotoxicity of cholic acid, deoxycholic acid and lithocholic acid in the rat: In vivo and in vitro studies. Toxicol Lett 61(2-3):291-304.
    • (1992) Toxicol Lett , vol.61 , Issue.2-3 , pp. 291-304
    • Delzenne, N.M.1    Calderon, P.B.2    Taper, H.S.3    Roberfroid, M.B.4
  • 45
    • 0032437785 scopus 로고    scopus 로고
    • Efflux of taurocholic acid across the blood-brain barrier: Interaction with cyclic peptides
    • Kitazawa T, Terasaki T, Suzuki H, Kakee A, Sugiyama Y. 1998. Efflux of taurocholic acid across the blood-brain barrier: Interaction with cyclic peptides. J Pharmacol Exp Ther 286(2):890-895.
    • (1998) J Pharmacol Exp Ther , vol.286 , Issue.2 , pp. 890-895
    • Kitazawa, T.1    Terasaki, T.2    Suzuki, H.3    Kakee, A.4    Sugiyama, Y.5
  • 46
    • 17644364387 scopus 로고    scopus 로고
    • Rat brain endothelial cell lines for the study of blood-brain barrier permeability and transport functions
    • Roux F, Couraud PO. 2005. Rat brain endothelial cell lines for the study of blood-brain barrier permeability and transport functions. Cell Mol Neurobiol 25(1):41-58.
    • (2005) Cell Mol Neurobiol , vol.25 , Issue.1 , pp. 41-58
    • Roux, F.1    Couraud, P.O.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.