Mitochondrial optic neuropathies: Our travels from bench to bedside and back again

Clinical and Experimental Ophthalmology

Volumn 41, Issue 7, 2013, Pages 702-712

  Sadun, Alfredo A ^a   La Morgia, Chiara ^b,c   Carelli, Valerio ^a,b,c  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b IRCCS ISTITUTO DELLE SCIENZE NEUROLOGICHE DI BOLOGNA   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Leber's hereditary optic neuropathy; Mitochondria; Optic nerve

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; CHLORAMPHENICOL; ETHAMBUTOL; IDEBENONE; LINEZOLID; METAL ION; MITOCHONDRIAL DNA; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MYELIN; PLACEBO; ROTENONE; STREPTOMYCIN; TETRACYCLINE DERIVATIVE; UBIDECARENONE;

ALCOHOL CONSUMPTION; BLINDNESS; CELL MEMBRANE STEADY POTENTIAL; CENTRAL NERVOUS SYSTEM; COLOR VISION DEFECT; COPY NUMBER VARIATION; ENERGY CONSUMPTION; EPIGENETICS; GENE LOCUS; GENE MUTATION; GENETIC SCREENING; HETEROPLASMY; HISTOPATHOLOGY; HUMAN; LEBER HEREDITARY OPTIC NEUROPATHY; MELAS SYNDROME; MERRF SYNDROME; NERVE FIBER; NONHUMAN; OPHTHALMOLOGY; OXIDATIVE PHOSPHORYLATION; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SMOKING; VISUAL ACUITY;

LEBER'S HEREDITARY OPTIC NEUROPATHY; MITOCHONDRIA; OPTIC NERVE;

ANIMALS; ANTIOXIDANTS; BIOMEDICAL RESEARCH; DNA, MITOCHONDRIAL; HUMANS; MITOCHONDRIA; MITOCHONDRIAL DISEASES; OPTIC ATROPHY, HEREDITARY, LEBER; REACTIVE OXYGEN SPECIES; UBIQUINONE;

EID: 84884981630     PISSN: 14426404     EISSN: 14429071     Source Type: Journal    
DOI: 10.1111/ceo.12086     Document Type: Review

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