Bioenergetics shapes cellular death pathways in Leber's hereditary optic neuropathy: A model of mitochondrial neurodegeneration

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1658, Issue 1-2, 2004, Pages 172-179

  Carelli, Valerio ^a   Rugolo, Michela ^a   Sgarbi, Gianluca ^b   Ghelli, Anna ^a   Zanna, Claudia ^a   Baracca, Alessandra ^a   Lenaz, Giorgio ^a   Napoli, Eleonora ^c   Martinuzzi, Andrea ^c   Solaini, Giancarlo ^b  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b SCUOLA SUPERIORE SANT ANNA   (Italy)

^c SCIENTIFIC INSTITUTE   (Italy)

Author keywords

Apoptosis; ATP synthesis; Complex I; LHON; Mitochondria; ROS

Indexed keywords

1,4 BENZOQUINONE; ADENOSINE TRIPHOSPHATE; ANTIOXIDANT; GALACTOSE; GLUCOSE; MITOCHONDRIAL DNA; MYXOTHIAZOL; PROTON; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (QUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE;

ALCOHOL CONSUMPTION; BIOENERGY; CELL DEATH; CELL LOSS; CULTURE MEDIUM; CYBRID; ENZYME SUBSTRATE; EUKARYOTE; GENE MUTATION; HUMAN; LEBER HEREDITARY OPTIC NEUROPATHY; MITOCHONDRION; MOLECULAR MODEL; NERVE CELL; NERVE DEGENERATION; NONHUMAN; OPTIC NERVE ATROPHY; OXIDATIVE STRESS; POINT MUTATION; PREVALENCE; PRIORITY JOURNAL; PROTON TRANSPORT; RESPIRATORY CHAIN; RETINA; REVIEW; SMOKING; SYNTHESIS; VISUAL IMPAIRMENT;

ANIMALS; CELL DEATH; CELLS, CULTURED; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT COMPLEX I; ENERGY METABOLISM; HUMANS; OPTIC ATROPHY, HEREDITARY, LEBER; OXIDATION-REDUCTION; POINT MUTATION; REACTIVE OXYGEN SPECIES;

EID: 3543025191     PISSN: 00052728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbabio.2004.05.009     Document Type: Review

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