메뉴 건너뛰기




Volumn 76, Issue , 2013, Pages 84-93

Microcystin-LR induces autophagy and apoptosis in rat Sertoli cells invitro

Author keywords

Apoptosis; Autophagosome accumulation; Autophagy; MC LR; Sertoli cell

Indexed keywords

3 METHYLADENINE; MESSENGER RNA; MICROCYSTIN LR; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN LIGHT CHAIN 3; UNCLASSIFIED DRUG; 3-METHYLADENINE; CYTOCHROME C; LACTATE DEHYDROGENASE; LC3 PROTEIN, RAT; MICROCYSTIN; CELL PROTEIN; PROTEIN LC3;

EID: 84884971696     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2013.09.005     Document Type: Article
Times cited : (59)

References (45)
  • 1
    • 67649414226 scopus 로고    scopus 로고
    • Morphological and ultrastructural effects of microcystin-LR from Microcystis aeruginosa extract on a kidney cell line
    • Alverca E., Andrade M., Dias E., Sam Bento F., Batoréu M.C.C., Jordan P., Silva M.J., Pereira P. Morphological and ultrastructural effects of microcystin-LR from Microcystis aeruginosa extract on a kidney cell line. Toxicon 2009, 54:283-294.
    • (2009) Toxicon , vol.54 , pp. 283-294
    • Alverca, E.1    Andrade, M.2    Dias, E.3    Sam Bento, F.4    Batoréu, M.C.C.5    Jordan, P.6    Silva, M.J.7    Pereira, P.8
  • 2
    • 39749141485 scopus 로고    scopus 로고
    • The regulation and function of Class III PI3Ks: novel roles for Vps34
    • Backer J.M. The regulation and function of Class III PI3Ks: novel roles for Vps34. Biochem. J. 2008, 410:1-17.
    • (2008) Biochem. J. , vol.410 , pp. 1-17
    • Backer, J.M.1
  • 4
    • 20344387475 scopus 로고    scopus 로고
    • Autophagy: dual roles in life and death?
    • Baehrecke E.H. Autophagy: dual roles in life and death?. Nat. Rev. Mol. Cell Biol. 2005, 6:505-510.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 505-510
    • Baehrecke, E.H.1
  • 6
    • 18244392443 scopus 로고    scopus 로고
    • Cell death independent of caspases: a review
    • Broker L.E., Kruyt F.A., Giaccone G. Cell death independent of caspases: a review. Clin. Cancer Res. 2005, 11:3155-3162.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 3155-3162
    • Broker, L.E.1    Kruyt, F.A.2    Giaccone, G.3
  • 7
    • 15044358224 scopus 로고    scopus 로고
    • Tissue distributions and seasonal dynamics of the hepatotoxic microcystins-LR and -RR in two freshwater shrimps, Palaemon modestus and Macrobrachium nipponensis, from a large shallow, eutrophic lake of the subtropical China
    • Chen J., Xie P. Tissue distributions and seasonal dynamics of the hepatotoxic microcystins-LR and -RR in two freshwater shrimps, Palaemon modestus and Macrobrachium nipponensis, from a large shallow, eutrophic lake of the subtropical China. Toxicon 2005, 45:615-625.
    • (2005) Toxicon , vol.45 , pp. 615-625
    • Chen, J.1    Xie, P.2
  • 8
    • 11144257676 scopus 로고    scopus 로고
    • Tissue distributions and seasonal dynamics of the hepatotoxic microcystins-LR and -RR in a freshwater snail (Bellamya aeruginosa) from a large shallow, eutrophic lake of the subtropical China
    • Chen J., Xie P., Guo L., Zheng L., Ni L. Tissue distributions and seasonal dynamics of the hepatotoxic microcystins-LR and -RR in a freshwater snail (Bellamya aeruginosa) from a large shallow, eutrophic lake of the subtropical China. Environ. Pollut. 2005, 134:423-430.
    • (2005) Environ. Pollut. , vol.134 , pp. 423-430
    • Chen, J.1    Xie, P.2    Guo, L.3    Zheng, L.4    Ni, L.5
  • 9
    • 61349165636 scopus 로고    scopus 로고
    • First identification of the hepatotoxic microcystins in the serum of a chronically exposed human population together with indication of hepatocellular damage
    • Chen J., Xie P., Li L., Xu J. First identification of the hepatotoxic microcystins in the serum of a chronically exposed human population together with indication of hepatocellular damage. Toxicol. Sci. 2009, 108:81-89.
    • (2009) Toxicol. Sci. , vol.108 , pp. 81-89
    • Chen, J.1    Xie, P.2    Li, L.3    Xu, J.4
  • 10
    • 79956369884 scopus 로고    scopus 로고
    • Decline of sperm quality and testicular function in male mice during chronic low-dose exposure to microcystin-LR
    • Chen Y., Xu J., Li Y., Han X. Decline of sperm quality and testicular function in male mice during chronic low-dose exposure to microcystin-LR. Reprod. Toxicol. 2011, 31:551-557.
    • (2011) Reprod. Toxicol. , vol.31 , pp. 551-557
    • Chen, Y.1    Xu, J.2    Li, Y.3    Han, X.4
  • 11
    • 79952441038 scopus 로고    scopus 로고
    • Induction of apoptotic cell death via accumulation of autophagosomes in rat granulosa cells
    • Choi J., Jo M., Lee E., Choi D. Induction of apoptotic cell death via accumulation of autophagosomes in rat granulosa cells. Fertil. Steril. 2011, 95:1482-1486.
    • (2011) Fertil. Steril. , vol.95 , pp. 1482-1486
    • Choi, J.1    Jo, M.2    Lee, E.3    Choi, D.4
  • 13
    • 0033733770 scopus 로고    scopus 로고
    • Cyanobacterial toxins, the perception of water quality, and the prioritisation of eutrophication control
    • Codd G.A. Cyanobacterial toxins, the perception of water quality, and the prioritisation of eutrophication control. Ecol. Eng. 2000, 16:51-60.
    • (2000) Ecol. Eng. , vol.16 , pp. 51-60
    • Codd, G.A.1
  • 14
    • 27644466759 scopus 로고    scopus 로고
    • Autophagy and signaling: their role in cell survival and cell death
    • Codogno P., Meijer A.J. Autophagy and signaling: their role in cell survival and cell death. Cell Death Differ. 2005, 12(Suppl. 2):1509-1518.
    • (2005) Cell Death Differ. , vol.12 , Issue.SUPPL. 2 , pp. 1509-1518
    • Codogno, P.1    Meijer, A.J.2
  • 15
    • 0023105617 scopus 로고
    • Ultrastructural changes in the mouse liver induced by hepatotoxin from the freshwater cyanobacterium Microcystis aeruginosa strain 7820
    • Dabholkar A.S., Carmichael W.W. Ultrastructural changes in the mouse liver induced by hepatotoxin from the freshwater cyanobacterium Microcystis aeruginosa strain 7820. Toxicon 1987, 25:285-292.
    • (1987) Toxicon , vol.25 , pp. 285-292
    • Dabholkar, A.S.1    Carmichael, W.W.2
  • 16
    • 7744235672 scopus 로고    scopus 로고
    • Death by design: apoptosis, necrosis and autophagy
    • Edinger A.L., Thompson C.B. Death by design: apoptosis, necrosis and autophagy. Curr. Opin. Cell Biol. 2004, 16:663-669.
    • (2004) Curr. Opin. Cell Biol. , vol.16 , pp. 663-669
    • Edinger, A.L.1    Thompson, C.B.2
  • 17
    • 67549142261 scopus 로고    scopus 로고
    • Life and death partners: apoptosis, autophagy and the cross-talk between them
    • Eisenberg-Lerner A., Bialik S., Simon H.U., Kimchi A. Life and death partners: apoptosis, autophagy and the cross-talk between them. Cell Death Differ. 2009, 16:966-975.
    • (2009) Cell Death Differ. , vol.16 , pp. 966-975
    • Eisenberg-Lerner, A.1    Bialik, S.2    Simon, H.U.3    Kimchi, A.4
  • 18
    • 27644471129 scopus 로고    scopus 로고
    • Doctor Jekyll and Mister Hyde: autophagy can promote both cell survival and cell death
    • Eskelinen E.L. Doctor Jekyll and Mister Hyde: autophagy can promote both cell survival and cell death. Cell Death Differ. 2005, 12(Suppl. 2):1468-1472.
    • (2005) Cell Death Differ. , vol.12 , Issue.SUPPL. 2 , pp. 1468-1472
    • Eskelinen, E.L.1
  • 19
    • 58149260266 scopus 로고    scopus 로고
    • Oatp-associated uptake and toxicity of microcystins in primary murine whole brain cells
    • Feurstein D., Holst K., Fischer A., Dietrich D.R. Oatp-associated uptake and toxicity of microcystins in primary murine whole brain cells. Toxicol. Appl. Pharmacol. 2009, 234:247-255.
    • (2009) Toxicol. Appl. Pharmacol. , vol.234 , pp. 247-255
    • Feurstein, D.1    Holst, K.2    Fischer, A.3    Dietrich, D.R.4
  • 22
    • 38949178055 scopus 로고    scopus 로고
    • Human health risk assessment related to cyanotoxins exposure
    • Funari E., Testai E. Human health risk assessment related to cyanotoxins exposure. Crit. Rev. Toxicol. 2008, 38:97-125.
    • (2008) Crit. Rev. Toxicol. , vol.38 , pp. 97-125
    • Funari, E.1    Testai, E.2
  • 23
    • 0032706891 scopus 로고    scopus 로고
    • Chemistry and structure activity relationships of bafilomycin A1, a potent and selective inhibitor of the vacuolar H+-ATPase
    • Gagliardi S., Rees M., Farina C. Chemistry and structure activity relationships of bafilomycin A1, a potent and selective inhibitor of the vacuolar H+-ATPase. Curr. Med. Chem. 1999, 6:1197-1212.
    • (1999) Curr. Med. Chem. , vol.6 , pp. 1197-1212
    • Gagliardi, S.1    Rees, M.2    Farina, C.3
  • 24
    • 0032822101 scopus 로고    scopus 로고
    • Recent advances of toxic cyanobacteria researches
    • Harada K. Recent advances of toxic cyanobacteria researches. J. Health Sci. 1999, 45:150-165.
    • (1999) J. Health Sci. , vol.45 , pp. 150-165
    • Harada, K.1
  • 25
    • 0034598658 scopus 로고    scopus 로고
    • Intratracheal administration of microcystin-LR, and its distribution
    • Ito E., Kondo F., Harada K. Intratracheal administration of microcystin-LR, and its distribution. Toxicon 2001, 39:265-271.
    • (2001) Toxicon , vol.39 , pp. 265-271
    • Ito, E.1    Kondo, F.2    Harada, K.3
  • 26
    • 0842287263 scopus 로고    scopus 로고
    • Effect of selenium-induced oxidative stress on the oxidation reduction system and reproductive ability of male mice
    • Kaur P., Bansal M.P. Effect of selenium-induced oxidative stress on the oxidation reduction system and reproductive ability of male mice. Biol. Trace Elem. Res. 2004, 97:83-93.
    • (2004) Biol. Trace Elem. Res. , vol.97 , pp. 83-93
    • Kaur, P.1    Bansal, M.P.2
  • 27
    • 34248583762 scopus 로고    scopus 로고
    • Methods for monitoring autophagy from yeast to human
    • Klionsky D.J., Cuervo A.M., Seglen P.O. Methods for monitoring autophagy from yeast to human. Autophagy 2007, 3:181-206.
    • (2007) Autophagy , vol.3 , pp. 181-206
    • Klionsky, D.J.1    Cuervo, A.M.2    Seglen, P.O.3
  • 28
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B., Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008, 132:27-42.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 29
    • 77956438065 scopus 로고    scopus 로고
    • Combined effects of two environmental endocrine disruptors nonyl phenol and di-n-butyl phthalate on rat Sertoli cells invitro
    • Li D., Hu Y., Shen X., Dai X., Han X. Combined effects of two environmental endocrine disruptors nonyl phenol and di-n-butyl phthalate on rat Sertoli cells invitro. Reprod. Toxicol. 2010, 30:438-445.
    • (2010) Reprod. Toxicol. , vol.30 , pp. 438-445
    • Li, D.1    Hu, Y.2    Shen, X.3    Dai, X.4    Han, X.5
  • 30
    • 62549099961 scopus 로고    scopus 로고
    • Cytotoxicity and oxidative stress study in cultured rat Sertoli cells with methyl tert-butyl ether (MTBE) exposure
    • Li D., Liu Q., Gong Y., Huang Y., Han X. Cytotoxicity and oxidative stress study in cultured rat Sertoli cells with methyl tert-butyl ether (MTBE) exposure. Reprod. Toxicol. 2009, 27:170-176.
    • (2009) Reprod. Toxicol. , vol.27 , pp. 170-176
    • Li, D.1    Liu, Q.2    Gong, Y.3    Huang, Y.4    Han, X.5
  • 31
    • 84862803695 scopus 로고    scopus 로고
    • Microcystin-LR causes cytotoxicity effects in rat testicular Sertoli cells
    • Li Y., Han X. Microcystin-LR causes cytotoxicity effects in rat testicular Sertoli cells. Environ. Toxicol. Pharmacol. 2012, 33:318-326.
    • (2012) Environ. Toxicol. Pharmacol. , vol.33 , pp. 318-326
    • Li, Y.1    Han, X.2
  • 32
    • 55949089946 scopus 로고    scopus 로고
    • The toxic effects of microcystin-LR on the reproductive system of male rats invivo and invitro
    • Li Y., Sheng J., Sha J., Han X. The toxic effects of microcystin-LR on the reproductive system of male rats invivo and invitro. Reprod. Toxicol. 2008, 26:239-245.
    • (2008) Reprod. Toxicol. , vol.26 , pp. 239-245
    • Li, Y.1    Sheng, J.2    Sha, J.3    Han, X.4
  • 33
  • 34
    • 4344712684 scopus 로고    scopus 로고
    • Methods for monitoring autophagy
    • Mizushima N. Methods for monitoring autophagy. Int. J. Biochem. Cell Biol. 2004, 36:2491-2502.
    • (2004) Int. J. Biochem. Cell Biol. , vol.36 , pp. 2491-2502
    • Mizushima, N.1
  • 35
    • 36249025723 scopus 로고    scopus 로고
    • Autophagy: process and function
    • Mizushima N. Autophagy: process and function. Genes Dev. 2007, 21:2861-2873.
    • (2007) Genes Dev. , vol.21 , pp. 2861-2873
    • Mizushima, N.1
  • 36
    • 33847411960 scopus 로고    scopus 로고
    • Potent cytotoxicity of the phosphatase inhibitor microcystin LR and microcystin analogues in OATP1B1- and OATP1B3-expressing HeLa cells
    • Monks N.R., Liu S., Xu Y., Yu H., Bendelow A.S., Moscow J.A. Potent cytotoxicity of the phosphatase inhibitor microcystin LR and microcystin analogues in OATP1B1- and OATP1B3-expressing HeLa cells. Mol. Cancer Ther. 2007, 6:587-598.
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 587-598
    • Monks, N.R.1    Liu, S.2    Xu, Y.3    Yu, H.4    Bendelow, A.S.5    Moscow, J.A.6
  • 37
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes invivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai Z.N., Milliman C.L., Korsmeyer S.J. Bcl-2 heterodimerizes invivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 1993, 74:609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 38
    • 0033978633 scopus 로고    scopus 로고
    • Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells
    • Petiot A., Ogier-Denis E., Blommaart E.F., Meijer A.J., Codogno P. Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells. J. Biol. Chem. 2000, 275:992-998.
    • (2000) J. Biol. Chem. , vol.275 , pp. 992-998
    • Petiot, A.1    Ogier-Denis, E.2    Blommaart, E.F.3    Meijer, A.J.4    Codogno, P.5
  • 41
    • 34249949759 scopus 로고    scopus 로고
    • Distribution and bioaccumulation of microcystins in water columns: a systematic investigation into the environmental fate and the risks associated with microcystins in Meiliang Bay, Lake Taihu
    • Song L., Chen W., Peng L., Wan N., Gan N., Zhang X. Distribution and bioaccumulation of microcystins in water columns: a systematic investigation into the environmental fate and the risks associated with microcystins in Meiliang Bay, Lake Taihu. Water Res. 2007, 41:2853-2864.
    • (2007) Water Res. , vol.41 , pp. 2853-2864
    • Song, L.1    Chen, W.2    Peng, L.3    Wan, N.4    Gan, N.5    Zhang, X.6
  • 42
    • 84855220947 scopus 로고    scopus 로고
    • Microcystin (-LR) affects hormones level of male mice by damaging hypothalamic-pituitary system
    • Wang X., Ying F., Chen Y., Han X. Microcystin (-LR) affects hormones level of male mice by damaging hypothalamic-pituitary system. Toxicon 2012, 59:205-214.
    • (2012) Toxicon , vol.59 , pp. 205-214
    • Wang, X.1    Ying, F.2    Chen, Y.3    Han, X.4
  • 43
    • 0344430177 scopus 로고    scopus 로고
    • Dynamics of microcystins-LR and -RR in the phytoplanktivorous silver carp in a sub-chronic toxicity experiment
    • Xie L., Xie P., Ozawa K., Honma T., Yokoyama A., Park H.D. Dynamics of microcystins-LR and -RR in the phytoplanktivorous silver carp in a sub-chronic toxicity experiment. Environ. Pollut. 2004, 127:431-439.
    • (2004) Environ. Pollut. , vol.127 , pp. 431-439
    • Xie, L.1    Xie, P.2    Ozawa, K.3    Honma, T.4    Yokoyama, A.5    Park, H.D.6
  • 44
    • 84872454400 scopus 로고    scopus 로고
    • A cyanobacterial toxin, microcystin-LR, induces apoptosis of sertoli cells by changing the expression levels of apoptosis-related proteins
    • Zhang H.Z., Zhang F.Q., Li C.F., Yi D., Fu X.L., Cui L.X. A cyanobacterial toxin, microcystin-LR, induces apoptosis of sertoli cells by changing the expression levels of apoptosis-related proteins. Tohoku J. Exp. Med. 2011, 224:235-242.
    • (2011) Tohoku J. Exp. Med. , vol.224 , pp. 235-242
    • Zhang, H.Z.1    Zhang, F.Q.2    Li, C.F.3    Yi, D.4    Fu, X.L.5    Cui, L.X.6
  • 45
    • 84861467696 scopus 로고    scopus 로고
    • The toxic effects of microcystin-LR on rat spermatogonia invitro
    • Zhou Y., Yuan J., Wu J., Han X. The toxic effects of microcystin-LR on rat spermatogonia invitro. Toxicol. Lett. 2012, 212:48-56.
    • (2012) Toxicol. Lett. , vol.212 , pp. 48-56
    • Zhou, Y.1    Yuan, J.2    Wu, J.3    Han, X.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.