Chemistry and structure activity relationships of bafilomycin A1, a potent and selective inhibitor of the vacuolar H+-ATPase

Current Medicinal Chemistry

Volumn 6, Issue 12, 1999, Pages 1197-1212

  Gagliardi, S ^a   Rees, M ^b   Farina, C ^a  

^a SmithKline Beecham SpA   (Italy)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BAFILOMYCIN A1; BAFILOMYCIN B1; BAFILOMYCIN C1; BAFILOMYCIN D; CONCANAMYCIN A; EFOMYCIN A; EFOMYCIN G; LEUCANIDICIN; PROTON PUMP INHIBITOR; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG; VIRANAMYCIN A; VIRUSTOMYCIN A;

ANIMAL CELL; ARTICLE; CATTLE; CELL VACUOLE; CHICKEN; CHROMAFFIN CELL; CONTROLLED STUDY; INTRACELLULAR TRANSPORT; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; PROTON TRANSPORT; STOMACH ACID SECRETION; STRUCTURE ACTIVITY RELATION; TRANSPORT KINETICS;

ANIMALS; ANTI-BACTERIAL AGENTS; DRUG DESIGN; ENZYME INHIBITORS; INHIBITORY CONCENTRATION 50; MACROLIDES; PROTON-TRANSLOCATING ATPASES; STREPTOMYCES; STRUCTURE-ACTIVITY RELATIONSHIP; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 0032706891     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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