Ulinastatin is a novel candidate drug for sepsis and secondary acute lung injury, evidence from an optimized CLP rat model

International Immunopharmacology

Volumn 17, Issue 3, 2013, Pages 799-807

  Wang, Ning ^a   Liu, Xin ^a   Zheng, Xinchuan ^a   Cao, Hongwei ^a   Wei, Guo ^a   Zhu, Yuanfeng ^a   Fan, Shijun ^a   Zhou, Hong ^b   Zheng, Jiang ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Candidate drug; CLP; Sepsis; Ulinastatin

Indexed keywords

ELASTASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA; ULINASTATIN;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD CLOTTING; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; DRUG EFFICACY; DRUG MECHANISM; ENZYME INHIBITION; LUNG PARENCHYMA; NONHUMAN; ORGAN INJURY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT MODEL; SEPSIS; SURVIVAL; SYSTEMIC DISEASE; TREATMENT OUTCOME;

CANDIDATE DRUG; CLP; SEPSIS; ULINASTATIN;

ACUTE LUNG INJURY; ANIMALS; ANTI-INFLAMMATORY AGENTS; CECUM; CELLS, CULTURED; DISEASE MODELS, ANIMAL; GLYCOPROTEINS; INTERLEUKIN-6; LIGATION; LUNG; NEUTROPHILS; NF-KAPPA B; RATS; RATS, SPRAGUE-DAWLEY; SEPSIS; TRYPSIN INHIBITORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84884970476     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2013.09.004     Document Type: Article

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