Sivelestat (selective neutrophil elastase inhibitor) improves the mortality rate of sepsis associated with both acute respiratory distress syndrome and disseminated intravascular coagulation patients

Shock

Volumn 33, Issue 1, 2010, Pages 14-18

  Hayakawa, Mineji ^a   Katabami, Kenichi ^a   Wada, Takeshi ^a   Sugano, Masahiro ^a   Hoshino, Hirokatsu ^a   Sawamura, Atsushi ^a   Gando, Satoshi ^a  

^a HOKKAIDO UNIVERSITY HOSPITAL   (Japan)

Author keywords

Acute lung injury; Critically ill patients; Leukocyte, endothelial cell; Protease

Indexed keywords

LEUKOCYTE ELASTASE INHIBITOR; SIVELESTAT;

ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; ARTICLE; CONTROLLED STUDY; CRITICALLY ILL PATIENT; DISSEMINATED INTRAVASCULAR CLOTTING; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME INHIBITION; FEMALE; HUMAN; INTENSIVE CARE UNIT; LENGTH OF STAY; LEUKOCYTE; LUNG INJURY; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PROGNOSIS; RETROSPECTIVE STUDY; SCORING SYSTEM; SEPSIS; SURVIVAL;

ADULT; AGED; DISSEMINATED INTRAVASCULAR COAGULATION; FEMALE; GLYCINE; HUMANS; MALE; MIDDLE AGED; RESPIRATORY DISTRESS SYNDROME, ADULT; RETROSPECTIVE STUDIES; SEPSIS; SERINE PROTEINASE INHIBITORS; SULFONAMIDES; TREATMENT OUTCOME;

EID: 73849113867     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e3181aa95c4     Document Type: Article

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