Urinary trypsin inhibitor reduces inflammatory response in kidney induced by Lipopolysaccharide

Journal of Bioscience and Bioengineering

Volumn 104, Issue 4, 2007, Pages 315-320

  Ueki, Masaaki ^a   Taie, Satoshi ^a   Chujo, Kousuke ^a   Asaga, Takehiko ^a   Iwanaga, Yasuyuki ^a   Ono, Junichiro ^a   Maekawa, Nobuhiro ^a  

^a KAGAWA UNIVERSITY   (Japan)

Author keywords

acute renal dysfunction; cytokine induced neutrophil chemoattractant 1 (CINC 1); lipopolysaccharide; neutrophil; tumor necrosis factor alpha; urinary trypsin inhibitor

Indexed keywords

BIOLOGICAL ORGANS; DRUG DOSAGE; PATIENT TREATMENT; RATS; TISSUE;

ACUTE RENAL DYSFUNCTION; PROINFLAMMATORY CYTOKINES; TUMOR NECROSIS FACTOR ALPHA;

ENZYME INHIBITION;

CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; LIPOPOLYSACCHARIDE; MYELOPEROXIDASE; TUMOR NECROSIS FACTOR ALPHA; ULINASTATIN;

ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; HISTOPATHOLOGY; INFLAMMATION; KIDNEY FUNCTION; KIDNEY INJURY; LEUKOCYTE ACTIVATION; MALE; NONHUMAN; RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCOPROTEINS; KIDNEY; LIPOPOLYSACCHARIDES; MALE; NEPHRITIS; RATS; RATS, WISTAR;

RATTUS;

EID: 36048985321     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1263/jbb.104.315     Document Type: Article

References (34)

1. Michie H.R., Manogue K.R., Spriggs D.R., Revhaug A., O'Dwyer S., Dinarello C.A., Cerami A., Wolff S.M., and Wilmore D.W. Detection of circulating tumor necrosis factor after endotoxin administration. N. Engl. J. Med. 318 (1988) 1481-1486
2. Parrillo J.E. Pathogenetic mechanisms of septic shock. N. Engl. J. Med. 328 (1993) 1471-1477
3. De Vriese A.S. Prevention and treatment of acute renal failure in sepsis. J. Am. Soc. Nephrol. 14 (2003) 792-805
4. Cohen J. The immunopathogenesis of sepsis. Nature 420 (2002) 885-891
5. Brown K.A., Brain S.D., Pearson J.D., Edgeworth J.D., Lewis S.M., and Treacher D.F. Neutrophils in development of multiple organ failure in sepsis. Lancet 368 (2006) 157-169
6. Jonsson-Berling B.M., Ohlsson K., and Rosengren M. Radioimmunological quantitation of the urinary trypsin inhibitor in normal blood and urine. Biol. Chem. Hoppe-Seyler 370 (1989) 1157-1161
7. Morishita H., Yamakawa T., Matsusue T., Kusuyama T., Sameshima-Aruga R., Hirose J., Nii A., Miura T., Isaji M., Horisawa-Nakano R., and other 13 authors. Novel factor Xa and plasma kallikrein inhibitory-activities of the second Kunitz-type inhibitory domain of urinary trypsin inhibitor. Thromb. Res. 73 (1994) 193-204
8. Aosasa S., Ono S., Mochizuki H., Tsujimoto H., Ueno C., and Matsumoto A. Mechanism of the inhibitory effect of protease inhibitor on tumor necrosis factor alpha production of monocytes. Shock 15 (2001) 101-105
9. Yamaguchi Y., Ohshiro H., Nagao Y., Odawara K., Okabe K., Hidaka H., Ishihara K., Uchino S., Furuhashi T., Yamada S., Mori K., and Ogawa M. Urinary trypsin inhibitor reduces C-X-C chemokine production in rat liver ischemia/reperfusion. J. Surg. Res. 94 (2000) 107-115
10. Guo R., Wnag Y., Minto A.W., Quigg R.J., and Cunningham P.N. Acute renal failure in endotoxemia is dependent on caspase activation. J. Am. Soc. Nephrol. 15 (2004) 3093-3102
11. Groeneveld A.B., Tran D.D., van der Meulen J., Nauta J.J., and Thijs L.G. Acute renal failure in the medical intensive care unit: predisposing, complicating factors and outcome. Nephron 59 (1991) 602-610
12. Neveu H., Kleinknecht D., Brivet F., Loirat P., and Landais P. Prognostic factors in acute renal failure due to sepsis. Results of a prospective multicentre study. The French Study Group on Acute Renal Failure. Nephrol. Dial. Transplant. 11 (1996) 293-299
13. Beutler B.A., Milsark I.W., and Cerami A. Cachectin/tumor necrosis factor: production, distribution, and metabolic fate in vivo. J. Immunol. 135 (1985) 3972-3977
14. Van Deventer S.J., Buller H.R., ten Cate J.W., Aarden L.A., Hack C.E., and Sturk A. Experimental endotoxemia in humans: analysis of cytokine release and coagulation, fibrinolytic, and complement pathways. Blood 76 (1990) 2520-2526
15. Linas S.L., Whittenburg D., and Repine J.E. Role of neutrophil derived oxidants and elastase in lipopolysaccharide-mediated renal injury. Kidney Int. 39 (1991) 618-623
16. Guthrie L.A., McPhail C., Henson P.M., and Johnston Jr. R.B. Priming of neutrophils for enhanced release of oxygen metabolites by bacterial lipopolysaccharide. Evidence for increased activity of the superoxide-producing enzyme. J. Exp. Med. 160 (1984) 1656-1671
17. Smedly L.A., Tonnesen M.G., Sandhaus R.A., Haslett C., Guthrie L.A., Johnston Jr. R.B., Henson P.M., and Worthen G.S. Neutrophil-mediated injury to endothelial cells. Enhancement by endotoxin and essential role of neutrophil elastase. J. Clin. Invest. 77 (1986) 1233-1243
18. Weiss S.J. Tissue destruction by neutrophils. N. Engl. J. Med. 320 (1989) 365-376
19. Deng X., Wang X., Lasson A., Sun T.Z., Soltesz V., and Andersson R. The involvement of multiple protease-antiprotease systems and gut origin sepsis in zymosan-associated endothelial barrier injury and multiple organ dysfunction in rats. Shock 16 (2001) 298-303
20. Lehrer R.I., Ganz T., Selsted M.E., Babior B.M., and Curnutte J.T. Neutrophils and host defense. Ann. Intern. Med. 109 (1988) 127-142
21. Molor-Erdene P., Okajima K., Isobe H., Uchiba M., Harada N., and Okabe H. Urinary trypsin inhibitor reduces LPS-induced hypotension by suppressing tumor necrosis factor-alpha production through inhibition of Egr-1 expression. Am. J. Physiol. Heart Circ. Physiol. 288 (2005) H1265-H1271
22. Matsushima K., Morishita K., Yoshimura T., Lavu S., Kobayashi Y., Lew W.E., Kung H.F., Leonard E.J., and Oppenheim J.J. Molecular cloning of a human monocyte-derived neutrophil chemotactic factor (MDNCF) and the induction of MDNCF mRNA by interleukin 1 and tumor necrosis factor. J. Exp. Med. 167 (1988) 1883-1893
23. Strieter R.M., Kunkel S.L., Showell H.J., Remick D.G., Phan S.H., Ward P.A., and Marks R.M. Endothelial cell gene expression of a neutrophil chemotactic factor by TNF-alpha, LPS, and IL-1 beta. Science 243 (1989) 1467-1469
24. Sekido N., Mukaida N., Harada A., Nakanishi I., Watanabe Y., and Matsushima K. Prevention of lung reperfusion injury in rabbits by a monoclonal antibody against interleukin-8. Nature 365 (1993) 654-657
25. Maehara K., Kanayama N., Halim A., el Maradny E., Oda T., Fujita M., and Terao T. Down-regulation of interleukin-8 gene expression in HL60 cell line by human Kunitz-type trypsin inhibitor. Biochem. Biophys. Res. Commun. 206 (1995) 927-934
26. Nakagawa H., Komori N., Shibata F., Ikesue A., Konishi K., Fujioka M., and Kato H. Identification of cytokine-induced neutrophil chemoattractants (CINC), rat GRO/CINC-2 alpha and CINC-2 beta, produced by granulation tissue in culture: purification, complete amino acid sequences and characterization. Biochem. J. 301 (1994) 545-550
27. Krawisz J.E., Sharon P., and Stenson W.F. Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models. Gastroenterology 87 (1984) 1344-1350
28. Hirose J., Ozawa T., Miura T., Isaji M., Nagao Y., Yamashiro K., Nii A., Kato K., and Uemura A. Human neutrophil elastase degrades inter-alpha-trypsin inhibitor to liberate urinary trypsin inhibitor related proteins. Biol. Pharm. Bull. 21 (1998) 651-656
29. Inoue K., Takano H., Shimada A., Yanagisawa R., Sakurai M., Yoshino S., Sato H., and Yoshikawa T. Urinary trypsin inhibitor protects against systemic inflammation induced by lipopolysaccharide. Mol. Pharmacol. 67 (2005) 673-680
30. Sato Y., Ishikawa S., Otaki A., Takahashi T., Hasegawa Y., Suzuki M., Yamagishi T., and Morishita Y. Induction of acute-phase reactive substances during open-heart surgery and efficacy of ulinastatin. Inhibiting cytokines and postoperative organ injury. Jpn. J. Thorac. Cardiovasc. Surg. 48 (2000) 428-434
31. Ito K., Mizutani A., Kira S., Mori M., Iwasaka H., and Noguchi T. Effect of Ulinastatin, a human urinary trypsin inhibitor, on the oleic acid-induced acute lung injury in rats via the inhibition of activated leukocytes. Injury 36 (2005) 387-394
32. Taie S., Yokono S., Ueki M., and Ogli K. Effects of ulinastatin (urinary trypsin inhibitor) on ATP, intracellular pH, and intracellular sodium transients during ischemia and reperfusion in the rat kidney in vivo. J. Anesth. 15 (2001) 33-38
33. Ueki M., Yokono S., and Ogli K. Effects of ulinastatin on rat renal energy metabolism and blood flow in hemorrhagic shock. J. Anesth. 9 (1995) 65-69
34. Fries E., and Blom A.M. Bikunin-not just a plasma proteinase inhibitor. Int. J. Biochem. Cell Biol. 32 (2000) 125-137