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Volumn 182, Issue 2, 2013, Pages 296-302

Ulinastatin improves survival of septic mice by suppressing inflammatory response and lymphocyte apoptosis

Author keywords

Apoptosis; Sepsis; Treatment; Ulinastatin

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA; ULINASTATIN;

EID: 84877713591     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2012.10.043     Document Type: Article
Times cited : (36)

References (28)
  • 1
    • 0034958947 scopus 로고    scopus 로고
    • Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
    • D.C. Angus, W.T. Linde-Zwirble, and J. Lidicker Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care Crit Care Med 29 2001 1303
    • (2001) Crit Care Med , vol.29 , pp. 1303
    • Angus, D.C.1    Linde-Zwirble, W.T.2    Lidicker, J.3
  • 2
    • 0029903114 scopus 로고    scopus 로고
    • Sir Isaac Newton, sepsis, SIRS, and CARS
    • R.C. Bone Sir Isaac Newton, sepsis, SIRS, and CARS Crit Care Med 24 1996 1125
    • (1996) Crit Care Med , vol.24 , pp. 1125
    • Bone, R.C.1
  • 4
    • 0037426726 scopus 로고    scopus 로고
    • The pathophysiology and treatment of sepsis
    • R.S. Hotchkiss, and I.E. Karl The pathophysiology and treatment of sepsis N Engl J Med 348 2003 138
    • (2003) N Engl J Med , vol.348 , pp. 138
    • Hotchkiss, R.S.1    Karl, I.E.2
  • 5
    • 14244260288 scopus 로고    scopus 로고
    • Pathophysiology and diagnostic value of urinary trypsin inhibitors
    • M.J. Pugia, and J.A. Lott Pathophysiology and diagnostic value of urinary trypsin inhibitors Clin Chem Lab Med 43 2005 1
    • (2005) Clin Chem Lab Med , vol.43 , pp. 1
    • Pugia, M.J.1    Lott, J.A.2
  • 6
    • 77955653376 scopus 로고    scopus 로고
    • Urinary trypsin inhibitor suppresses excessive generation of superoxide anion radical, systemic inflammation, oxidative stress, and endothelial injury in endotoxemic rats
    • R. Tanaka, M. Fujita, and R. Tsuruta Urinary trypsin inhibitor suppresses excessive generation of superoxide anion radical, systemic inflammation, oxidative stress, and endothelial injury in endotoxemic rats Inflamm Res 59 2010 597
    • (2010) Inflamm Res , vol.59 , pp. 597
    • Tanaka, R.1    Fujita, M.2    Tsuruta, R.3
  • 7
    • 81455141331 scopus 로고    scopus 로고
    • Ulinastatin improves pulmonary function in severe burn-induced acute lung injury by attenuating inflammatory response
    • Y. Fang, P. Xu, and C. Gu Ulinastatin improves pulmonary function in severe burn-induced acute lung injury by attenuating inflammatory response J Trauma 71 2011 1297
    • (2011) J Trauma , vol.71 , pp. 1297
    • Fang, Y.1    Xu, P.2    Gu, C.3
  • 8
    • 22144444213 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-induced tissue factor expression in monocytes by urinary trypsin inhibitor in vitro and in vivo
    • P. Molor-Erdene, K. Okajima, and H. Isobe Inhibition of lipopolysaccharide-induced tissue factor expression in monocytes by urinary trypsin inhibitor in vitro and in vivo Thromb Haemost 94 2005 136
    • (2005) Thromb Haemost , vol.94 , pp. 136
    • Molor-Erdene, P.1    Okajima, K.2    Isobe, H.3
  • 9
    • 70350689765 scopus 로고    scopus 로고
    • Protective role of urinary trypsin inhibitor in lung expression of proinflammatory cytokines accompanied by lethal liver injury in mice
    • K. Inoue, H. Takano, H. Sato, R. Yanagisawa, and T. Yoshikawa Protective role of urinary trypsin inhibitor in lung expression of proinflammatory cytokines accompanied by lethal liver injury in mice Immunopharmacol Immunotoxicol 31 2009 446
    • (2009) Immunopharmacol Immunotoxicol , vol.31 , pp. 446
    • Inoue, K.1    Takano, H.2    Sato, H.3    Yanagisawa, R.4    Yoshikawa, T.5
  • 10
    • 67649875342 scopus 로고    scopus 로고
    • Urinary trypsin inhibitor protects against liver injury and coagulation pathway dysregulation induced by lipopolysaccharide/D-galactosamine in mice
    • H. Takano, K. Inoue, and A. Shimada Urinary trypsin inhibitor protects against liver injury and coagulation pathway dysregulation induced by lipopolysaccharide/D-galactosamine in mice Lab Invest 89 2009 833
    • (2009) Lab Invest , vol.89 , pp. 833
    • Takano, H.1    Inoue, K.2    Shimada, A.3
  • 11
    • 36048985321 scopus 로고    scopus 로고
    • Urinary trypsin inhibitor reduces inflammatory response in kidney induced by lipopolysaccharide
    • M. Ueki, S. Taie, and K. Chujo Urinary trypsin inhibitor reduces inflammatory response in kidney induced by lipopolysaccharide J Biosci Bioeng 104 2007 315
    • (2007) J Biosci Bioeng , vol.104 , pp. 315
    • Ueki, M.1    Taie, S.2    Chujo, K.3
  • 12
    • 84866037504 scopus 로고    scopus 로고
    • Protective effects of ulinastatin on pulmonary damage in rats following scald injury
    • C. Gao, Y. Liu, L. Ma, and S. Wang Protective effects of ulinastatin on pulmonary damage in rats following scald injury Burns 38 2012 1027
    • (2012) Burns , vol.38 , pp. 1027
    • Gao, C.1    Liu, Y.2    Ma, L.3    Wang, S.4
  • 13
    • 77953470355 scopus 로고    scopus 로고
    • The effect of ulinastatin on hemostasis in major orthopedic surgery
    • J.Y. Lee, J.Y. Chon, H.S. Moon, and S.J. Hong The effect of ulinastatin on hemostasis in major orthopedic surgery Korean J Anesthesiol 58 2010 25
    • (2010) Korean J Anesthesiol , vol.58 , pp. 25
    • Lee, J.Y.1    Chon, J.Y.2    Moon, H.S.3    Hong, S.J.4
  • 15
    • 0026511205 scopus 로고
    • Polymicrobial sepsis selectively activates peritoneal but not alveolar macrophages to release inflammatory mediators (interleukins-1 and -6 and tumor necrosis factor)
    • A. Ayala, M.M. Perrin, J.M. Kisala, W. Ertel, and I.H. Chaudry Polymicrobial sepsis selectively activates peritoneal but not alveolar macrophages to release inflammatory mediators (interleukins-1 and -6 and tumor necrosis factor) Circ Shock 36 1992 191
    • (1992) Circ Shock , vol.36 , pp. 191
    • Ayala, A.1    Perrin, M.M.2    Kisala, J.M.3    Ertel, W.4    Chaudry, I.H.5
  • 16
    • 0036051160 scopus 로고    scopus 로고
    • Influence of a human protease inhibitor on surgical stress induced immunosuppression
    • N. Sato, S. Endo, and Y. Kimura Influence of a human protease inhibitor on surgical stress induced immunosuppression Dig Surg 19 2002 300
    • (2002) Dig Surg , vol.19 , pp. 300
    • Sato, N.1    Endo, S.2    Kimura, Y.3
  • 17
    • 34347204795 scopus 로고    scopus 로고
    • Bikunin (urinary trypsin inhibitor): Structure, biological relevance, and measurement
    • M.J. Pugia, R. Valdes Jr., and S.A. Jortani Bikunin (urinary trypsin inhibitor): structure, biological relevance, and measurement Adv Clin Chem 44 2007 223
    • (2007) Adv Clin Chem , vol.44 , pp. 223
    • Pugia, M.J.1    Valdes Jr., R.2    Jortani, S.A.3
  • 18
    • 0023801387 scopus 로고
    • The human neutrophil serine proteinases, elastase and cathepsin G, can mediate glomerular injury in vivo
    • R.J. Johnson, W.G. Couser, and C.E. Alpers The human neutrophil serine proteinases, elastase and cathepsin G, can mediate glomerular injury in vivo J Exp Med 168 1988 1169
    • (1988) J Exp Med , vol.168 , pp. 1169
    • Johnson, R.J.1    Couser, W.G.2    Alpers, C.E.3
  • 19
    • 0035717034 scopus 로고    scopus 로고
    • Granzymes: A family of lymphocyte granule serine proteases
    • reviews3014.1
    • J.A. Trapani Granzymes: a family of lymphocyte granule serine proteases Genome Biol 2 2001 reviews3014.1
    • (2001) Genome Biol , vol.2
    • Trapani, J.A.1
  • 20
    • 0034615553 scopus 로고    scopus 로고
    • Granzymes (lymphocyte serine proteases): Characterization with natural and synthetic substrates and inhibitors
    • C.M. Kam, D. Hudig, and J.C. Powers Granzymes (lymphocyte serine proteases): characterization with natural and synthetic substrates and inhibitors Biochim Biophys Acta 1477 2000 307
    • (2000) Biochim Biophys Acta , vol.1477 , pp. 307
    • Kam, C.M.1    Hudig, D.2    Powers, J.C.3
  • 22
    • 16244397365 scopus 로고    scopus 로고
    • Neutrophil serine proteases: Potential key regulators of cell signalling during inflammation
    • O. Wiedow, and U. Meyer-Hoffert Neutrophil serine proteases: potential key regulators of cell signalling during inflammation J Intern Med 257 2005 319
    • (2005) J Intern Med , vol.257 , pp. 319
    • Wiedow, O.1    Meyer-Hoffert, U.2
  • 23
    • 0033071821 scopus 로고    scopus 로고
    • Thrombin and trypsin receptors: The same mechanism of signalling on cellular surfaces
    • T. Olejar, and K. Nouza Thrombin and trypsin receptors: the same mechanism of signalling on cellular surfaces Bratisl Lek Listy 100 1999 75
    • (1999) Bratisl Lek Listy , vol.100 , pp. 75
    • Olejar, T.1    Nouza, K.2
  • 24
    • 0033969341 scopus 로고    scopus 로고
    • Pro- versus anti-inflammatory cytokine profile in patients with severe sepsis: A marker for prognosis and future therapeutic options
    • C.A. Gogos, E. Drosou, H.P. Bassaris, and A. Skoutelis Pro- versus anti-inflammatory cytokine profile in patients with severe sepsis: a marker for prognosis and future therapeutic options J Infect Dis 181 2000 176
    • (2000) J Infect Dis , vol.181 , pp. 176
    • Gogos, C.A.1    Drosou, E.2    Bassaris, H.P.3    Skoutelis, A.4
  • 25
    • 17044413706 scopus 로고    scopus 로고
    • Accelerated lymphocyte death in sepsis occurs by both the death receptor and mitochondrial pathways
    • R.S. Hotchkiss, S.B. Osmon, and K.C. Chang Accelerated lymphocyte death in sepsis occurs by both the death receptor and mitochondrial pathways J Immunol 174 2005 5110
    • (2005) J Immunol , vol.174 , pp. 5110
    • Hotchkiss, R.S.1    Osmon, S.B.2    Chang, K.C.3
  • 26
    • 0036023614 scopus 로고    scopus 로고
    • Myocardial apoptosis and ischemic preconditioning
    • Z.Q. Zhao, and J. Vinten-Johansen Myocardial apoptosis and ischemic preconditioning Cardiovasc Res 55 2002 438
    • (2002) Cardiovasc Res , vol.55 , pp. 438
    • Zhao, Z.Q.1    Vinten-Johansen, J.2
  • 27
    • 84864506615 scopus 로고    scopus 로고
    • Protective effect of Ulinastatin against murine models of sepsis: Inhibition of TNF-alpha and IL-6 and augmentation of IL-10 and IL-13
    • Y.Z. Cao, Y.Y. Tu, and X. Chen Protective effect of Ulinastatin against murine models of sepsis: inhibition of TNF-alpha and IL-6 and augmentation of IL-10 and IL-13 Exp Toxicol Pathol 64 2012 543
    • (2012) Exp Toxicol Pathol , vol.64 , pp. 543
    • Cao, Y.Z.1    Tu, Y.Y.2    Chen, X.3
  • 28
    • 68349130226 scopus 로고    scopus 로고
    • The effect of ulinastatin on the small intestine injury and mast cell degranulation in a rat model of sepsis induced by CLP
    • Y.J. Zhang, M. Li, M. Meng, M. Feng, and C.Y. Qin The effect of ulinastatin on the small intestine injury and mast cell degranulation in a rat model of sepsis induced by CLP Exp Toxicol Pathol 61 2009 481
    • (2009) Exp Toxicol Pathol , vol.61 , pp. 481
    • Zhang, Y.J.1    Li, M.2    Meng, M.3    Feng, M.4    Qin, C.Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.