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Volumn 10, Issue 1, 2013, Pages

The combination of arsenic, interferon-alpha, and zidovudine restores an " immunocompetent-like" cytokine expression profile in patients with adult T-cell leukemia lymphoma

(20)  Kchour, Ghada a   Rezaee, SA R b   Farid, Reza b   Ghantous, Akram c   Rafatpanah, Houshang b   Tarhini, Mahdi d   Kooshyar, Mohamad Mehdi e   El Hajj, Hiba f   Berry, Fadwa a   Mortada, Mohamad a   Nasser, Roudaina f   Shirdel, Abbas e   Dassouki, Zeina f   Ezzedine, Mohamad a   Rahimi, Hossein e   Ghavamzadeh, Ardeshir g   de Thé, Hugues h   Hermine, Olivier i   Mahmoudi, Mahmoud b   Bazarbachi, Ali f  


Author keywords

Arsenic; ATL; Cytokines; HTLV I; Immune deficiency; Interferon; Zidovudine

Indexed keywords

ALPHA INTERFERON; ARSENIC TRIOXIDE; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; MESSENGER RNA; TRANSCRIPTION FACTOR FOXP3; ZIDOVUDINE;

EID: 84884966978     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-10-91     Document Type: Article
Times cited : (44)

References (53)
  • 1
    • 0019940257 scopus 로고
    • Antibodies to adult T-cell leukemia-virus-associated antigen (ATLA) in sera from patients with ATL and controls in Japan: a nation-wide sero-epidemiologic study
    • 10.1002/ijc.2910290606, 6980846
    • Hinuma Y, Komoda H, Chosa T, Kondo T, Kohakura M, Takenaka T, Kikuchi M, Ichimaru M, Yunoki K, Sato I, et al. Antibodies to adult T-cell leukemia-virus-associated antigen (ATLA) in sera from patients with ATL and controls in Japan: a nation-wide sero-epidemiologic study. Int J Cancer 1982, 29:631-635. 10.1002/ijc.2910290606, 6980846.
    • (1982) Int J Cancer , vol.29 , pp. 631-635
    • Hinuma, Y.1    Komoda, H.2    Chosa, T.3    Kondo, T.4    Kohakura, M.5    Takenaka, T.6    Kikuchi, M.7    Ichimaru, M.8    Yunoki, K.9    Sato, I.10
  • 2
    • 0019254359 scopus 로고
    • Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma
    • 10.1073/pnas.77.12.7415, 350514, 6261256
    • Poiesz BJ, Ruscetti FW, Gazdar AF, Bunn PA, Minna JD, Gallo RC. Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma. Proc Natl Acad Sci USA 1980, 77:7415-7419. 10.1073/pnas.77.12.7415, 350514, 6261256.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 7415-7419
    • Poiesz, B.J.1    Ruscetti, F.W.2    Gazdar, A.F.3    Bunn, P.A.4    Minna, J.D.5    Gallo, R.C.6
  • 4
    • 80051899384 scopus 로고    scopus 로고
    • How I treat adult T-cell leukemia/lymphoma
    • 10.1182/blood-2011-03-345702, 21673346
    • Bazarbachi A, Suarez F, Fields P, Hermine O. How I treat adult T-cell leukemia/lymphoma. Blood 2011, 118:1736-1745. 10.1182/blood-2011-03-345702, 21673346.
    • (2011) Blood , vol.118 , pp. 1736-1745
    • Bazarbachi, A.1    Suarez, F.2    Fields, P.3    Hermine, O.4
  • 5
    • 58549103931 scopus 로고    scopus 로고
    • Definition, prognostic factors, treatment, and response criteria of adult T-cell leukemia-lymphoma: a proposal from an international consensus meeting
    • 2737379, 19064971
    • Tsukasaki K, Hermine O, Bazarbachi A, Ratner L, Ramos JC, Harrington W, O'Mahony D, Janik JE, Bittencourt AL, Taylor GP, et al. Definition, prognostic factors, treatment, and response criteria of adult T-cell leukemia-lymphoma: a proposal from an international consensus meeting. J Clin Oncol 2009, 27:453-459. 2737379, 19064971.
    • (2009) J Clin Oncol , vol.27 , pp. 453-459
    • Tsukasaki, K.1    Hermine, O.2    Bazarbachi, A.3    Ratner, L.4    Ramos, J.C.5    Harrington, W.6    O'Mahony, D.7    Janik, J.E.8    Bittencourt, A.L.9    Taylor, G.P.10
  • 6
    • 0032425056 scopus 로고    scopus 로고
    • Adult T cell leukaemia: a review of established and new treatments
    • 10.2165/00063030-199810060-00003, 18020614
    • Hermine O, Wattel E, Gessain A, Bazarbachi A. Adult T cell leukaemia: a review of established and new treatments. BioDrugs 1998, 10:447-462. 10.2165/00063030-199810060-00003, 18020614.
    • (1998) BioDrugs , vol.10 , pp. 447-462
    • Hermine, O.1    Wattel, E.2    Gessain, A.3    Bazarbachi, A.4
  • 7
    • 0029783563 scopus 로고    scopus 로고
    • Adult T-cell leukemia/lymphoma in Jamaica: 1986-1995
    • Hanchard B. Adult T-cell leukemia/lymphoma in Jamaica: 1986-1995. J Acquir Immune Defic Syndr Hum Retrovirol 1996, 13(Suppl 1):S20-S25.
    • (1996) J Acquir Immune Defic Syndr Hum Retrovirol , vol.13 , Issue.SUPPL 1
    • Hanchard, B.1
  • 11
    • 80053356662 scopus 로고    scopus 로고
    • Human T-lymphotropic virus type 1 (HTLV-1) and regulatory T cells in HTLV-1-associated neuroinflammatory disease
    • 10.3390/v3091532, 3187691, 21994794
    • Araya N, Sato T, Yagishita N, Ando H, Utsunomiya A, Jacobson S, Yamano Y. Human T-lymphotropic virus type 1 (HTLV-1) and regulatory T cells in HTLV-1-associated neuroinflammatory disease. Viruses 2011, 3:1532-1548. 10.3390/v3091532, 3187691, 21994794.
    • (2011) Viruses , vol.3 , pp. 1532-1548
    • Araya, N.1    Sato, T.2    Yagishita, N.3    Ando, H.4    Utsunomiya, A.5    Jacobson, S.6    Yamano, Y.7
  • 12
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • 10.1126/science.1079490, 12522256
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003, 299:1057-1061. 10.1126/science.1079490, 12522256.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 13
    • 44849129837 scopus 로고    scopus 로고
    • Regulatory T cells in the past and for the future
    • 10.1002/eji.200890012, 18395855
    • Sakaguchi S. Regulatory T cells in the past and for the future. Eur J Immunol 2008, 38:901-937. 10.1002/eji.200890012, 18395855.
    • (2008) Eur J Immunol , vol.38 , pp. 901-937
    • Sakaguchi, S.1
  • 14
    • 0020662183 scopus 로고
    • Phenotypic and functional analysis of leukemic cells from 16 patients with adult T-cell leukemia/lymphoma
    • Yamada Y. Phenotypic and functional analysis of leukemic cells from 16 patients with adult T-cell leukemia/lymphoma. Blood 1983, 61:192-199.
    • (1983) Blood , vol.61 , pp. 192-199
    • Yamada, Y.1
  • 15
    • 25844507839 scopus 로고    scopus 로고
    • Possible origin of adult T-cell leukemia/lymphoma cells from human T lymphotropic virus type-1-infected regulatory T cells
    • 10.1111/j.1349-7006.2005.00080.x, 16108835
    • Kohno T, Yamada Y, Akamatsu N, Kamihira S, Imaizumi Y, Tomonaga M, Matsuyama T. Possible origin of adult T-cell leukemia/lymphoma cells from human T lymphotropic virus type-1-infected regulatory T cells. Cancer Sci 2005, 96:527-533. 10.1111/j.1349-7006.2005.00080.x, 16108835.
    • (2005) Cancer Sci , vol.96 , pp. 527-533
    • Kohno, T.1    Yamada, Y.2    Akamatsu, N.3    Kamihira, S.4    Imaizumi, Y.5    Tomonaga, M.6    Matsuyama, T.7
  • 17
    • 15044347382 scopus 로고    scopus 로고
    • Phenotypic and functional relationship between adult T-cell leukemia cells and regulatory T cells
    • 10.1038/sj.leu.2403628, 15674359
    • Matsubara Y, Hori T, Morita R, Sakaguchi S, Uchiyama T. Phenotypic and functional relationship between adult T-cell leukemia cells and regulatory T cells. Leukemia 2005, 19:482-483. 10.1038/sj.leu.2403628, 15674359.
    • (2005) Leukemia , vol.19 , pp. 482-483
    • Matsubara, Y.1    Hori, T.2    Morita, R.3    Sakaguchi, S.4    Uchiyama, T.5
  • 18
    • 0026095532 scopus 로고
    • Diagnostic criteria and classification of clinical subtypes of adult T-cell leukaemia-lymphoma: a report from the Lymphoma Study Group (1984-87)
    • 10.1111/j.1365-2141.1991.tb08051.x, 1751370
    • Shimoyama M. Diagnostic criteria and classification of clinical subtypes of adult T-cell leukaemia-lymphoma: a report from the Lymphoma Study Group (1984-87). Br J Haematol 1991, 79:428-437. 10.1111/j.1365-2141.1991.tb08051.x, 1751370.
    • (1991) Br J Haematol , vol.79 , pp. 428-437
    • Shimoyama, M.1
  • 19
    • 0034887099 scopus 로고    scopus 로고
    • Treatment of adult T-cell leukaemia/lymphoma: current strategy and future perspectives
    • 10.1016/S0168-1702(01)00286-6, 11520582
    • Bazarbachi A, Hermine O. Treatment of adult T-cell leukaemia/lymphoma: current strategy and future perspectives. Virus Res 2001, 78:79-92. 10.1016/S0168-1702(01)00286-6, 11520582.
    • (2001) Virus Res , vol.78 , pp. 79-92
    • Bazarbachi, A.1    Hermine, O.2
  • 20
    • 74249117327 scopus 로고    scopus 로고
    • Current management of adult T-cell leukemia/lymphoma
    • Tobinai K. Current management of adult T-cell leukemia/lymphoma. Oncology (Williston Park) 2009, 23:1250-1256.
    • (2009) Oncology (Williston Park) , vol.23 , pp. 1250-1256
    • Tobinai, K.1
  • 21
    • 1542639509 scopus 로고    scopus 로고
    • An intensive chemotherapy of adult T-cell leukemia/lymphoma: CHOP followed by etoposide, vindesine, ranimustine, and mitoxantrone with granulocyte colony-stimulating factor support
    • 10.1097/00042560-199606010-00012, 8680890
    • Taguchi H, Kinoshita KI, Takatsuki K, Tomonaga M, Araki K, Arima N, Ikeda S, Uozumi K, Kohno H, Kawano F, et al. An intensive chemotherapy of adult T-cell leukemia/lymphoma: CHOP followed by etoposide, vindesine, ranimustine, and mitoxantrone with granulocyte colony-stimulating factor support. J Acquir Immune Defic Syndr Hum Retrovirol 1996, 12:182-186. 10.1097/00042560-199606010-00012, 8680890.
    • (1996) J Acquir Immune Defic Syndr Hum Retrovirol , vol.12 , pp. 182-186
    • Taguchi, H.1    Kinoshita, K.I.2    Takatsuki, K.3    Tomonaga, M.4    Araki, K.5    Arima, N.6    Ikeda, S.7    Uozumi, K.8    Kohno, H.9    Kawano, F.10
  • 22
    • 0035004336 scopus 로고    scopus 로고
    • A new G-CSF-supported combination chemotherapy, LSG15, for adult T-cell leukaemia-lymphoma: Japan Clinical Oncology Group Study 9303
    • 10.1046/j.1365-2141.2001.02737.x, 11380402
    • Yamada Y, Tomonaga M, Fukuda H, Hanada S, Utsunomiya A, Tara M, Sano M, Ikeda S, Takatsuki K, Kozuru M, et al. A new G-CSF-supported combination chemotherapy, LSG15, for adult T-cell leukaemia-lymphoma: Japan Clinical Oncology Group Study 9303. Br J Haematol 2001, 113:375-382. 10.1046/j.1365-2141.2001.02737.x, 11380402.
    • (2001) Br J Haematol , vol.113 , pp. 375-382
    • Yamada, Y.1    Tomonaga, M.2    Fukuda, H.3    Hanada, S.4    Utsunomiya, A.5    Tara, M.6    Sano, M.7    Ikeda, S.8    Takatsuki, K.9    Kozuru, M.10
  • 24
    • 77957962485 scopus 로고    scopus 로고
    • Meta-analysis on the use of zidovudine and interferon-alfa in adult T-cell leukemia/lymphoma showing improved survival in the leukemic subtypes
    • 10.1200/JCO.2010.28.0669, 20585095
    • Bazarbachi A, Plumelle Y, Carlos Ramos J, Tortevoye P, Otrock Z, Taylor G, Gessain A, Harrington W, Panelatti G, Hermine O. Meta-analysis on the use of zidovudine and interferon-alfa in adult T-cell leukemia/lymphoma showing improved survival in the leukemic subtypes. J Clin Oncol 2010, 28:4177-4183. 10.1200/JCO.2010.28.0669, 20585095.
    • (2010) J Clin Oncol , vol.28 , pp. 4177-4183
    • Bazarbachi, A.1    Plumelle, Y.2    Carlos Ramos, J.3    Tortevoye, P.4    Otrock, Z.5    Taylor, G.6    Gessain, A.7    Harrington, W.8    Panelatti, G.9    Hermine, O.10
  • 26
    • 0034667621 scopus 로고    scopus 로고
    • Arsenic-interferon-alpha-triggered apoptosis in HTLV-I transformed cells is associated with tax down-regulation and reversal of NF-kappa B activation
    • El-Sabban ME, Nasr R, Dbaibo G, Hermine O, Abboushi N, Quignon F, Ameisen JC, Bex F, de The H, Bazarbachi A. Arsenic-interferon-alpha-triggered apoptosis in HTLV-I transformed cells is associated with tax down-regulation and reversal of NF-kappa B activation. Blood 2000, 96:2849-2855.
    • (2000) Blood , vol.96 , pp. 2849-2855
    • El-Sabban, M.E.1    Nasr, R.2    Dbaibo, G.3    Hermine, O.4    Abboushi, N.5    Quignon, F.6    Ameisen, J.C.7    Bex, F.8    de The, H.9    Bazarbachi, A.10
  • 27
    • 0038481253 scopus 로고    scopus 로고
    • Arsenic/interferon specifically reverses 2 distinct gene networks critical for the survival of HTLV-1-infected leukemic cells
    • 10.1182/blood-2002-09-2986, 12560223
    • Nasr R, Rosenwald A, El-Sabban ME, Arnulf B, Zalloua P, Lepelletier Y, Bex F, Hermine O, Staudt L, de The H, Bazarbachi A. Arsenic/interferon specifically reverses 2 distinct gene networks critical for the survival of HTLV-1-infected leukemic cells. Blood 2003, 101:4576-4582. 10.1182/blood-2002-09-2986, 12560223.
    • (2003) Blood , vol.101 , pp. 4576-4582
    • Nasr, R.1    Rosenwald, A.2    El-Sabban, M.E.3    Arnulf, B.4    Zalloua, P.5    Lepelletier, Y.6    Bex, F.7    Hermine, O.8    Staudt, L.9    de The, H.10    Bazarbachi, A.11
  • 28
    • 11144356179 scopus 로고    scopus 로고
    • Phase II trial of arsenic trioxide and alpha interferon in patients with relapsed/refractory adult T-cell leukemia/lymphoma
    • 10.1038/sj.thj.6200374, 15048063
    • Hermine O, Dombret H, Poupon J, Arnulf B, Lefrere F, Rousselot P, Damaj G, Delarue R, Fermand JP, Brouet JC, et al. Phase II trial of arsenic trioxide and alpha interferon in patients with relapsed/refractory adult T-cell leukemia/lymphoma. Hematol J 2004, 5:130-134. 10.1038/sj.thj.6200374, 15048063.
    • (2004) Hematol J , vol.5 , pp. 130-134
    • Hermine, O.1    Dombret, H.2    Poupon, J.3    Arnulf, B.4    Lefrere, F.5    Rousselot, P.6    Damaj, G.7    Delarue, R.8    Fermand, J.P.9    Brouet, J.C.10
  • 29
    • 78650373635 scopus 로고    scopus 로고
    • Therapy-induced selective loss of leukemia-initiating activity in murine adult T cell leukemia
    • 10.1084/jem.20101095, 3005222, 21135137
    • El Hajj H, El-Sabban M, Hasegawa H, Zaatari G, Ablain J, Saab ST, Janin A, Mahfouz R, Nasr R, Kfoury Y, et al. Therapy-induced selective loss of leukemia-initiating activity in murine adult T cell leukemia. J Exp Med 2010, 207:2785-2792. 10.1084/jem.20101095, 3005222, 21135137.
    • (2010) J Exp Med , vol.207 , pp. 2785-2792
    • El Hajj, H.1    El-Sabban, M.2    Hasegawa, H.3    Zaatari, G.4    Ablain, J.5    Saab, S.T.6    Janin, A.7    Mahfouz, R.8    Nasr, R.9    Kfoury, Y.10
  • 30
    • 69249235900 scopus 로고    scopus 로고
    • Phase 2 study of the efficacy and safety of the combination of arsenic trioxide, interferon alpha, and zidovudine in newly diagnosed chronic adult T-cell leukemia/lymphoma (ATL)
    • 10.1182/blood-2009-03-211821, 19411628
    • Kchour G, Tarhini M, Kooshyar MM, El Hajj H, Wattel E, Mahmoudi M, Hatoum H, Rahimi H, Maleki M, Rafatpanah H, et al. Phase 2 study of the efficacy and safety of the combination of arsenic trioxide, interferon alpha, and zidovudine in newly diagnosed chronic adult T-cell leukemia/lymphoma (ATL). Blood 2009, 113:6528-6532. 10.1182/blood-2009-03-211821, 19411628.
    • (2009) Blood , vol.113 , pp. 6528-6532
    • Kchour, G.1    Tarhini, M.2    Kooshyar, M.M.3    El Hajj, H.4    Wattel, E.5    Mahmoudi, M.6    Hatoum, H.7    Rahimi, H.8    Maleki, M.9    Rafatpanah, H.10
  • 31
    • 33646410446 scopus 로고    scopus 로고
    • Clinical significance of serum Th1-, Th2- and regulatory T cells-associated cytokines in adult T-cell leukemia/lymphoma: high interleukin-5 and -10 levels are significant unfavorable prognostic factors
    • 10.1002/ijc.21688, 16425276
    • Inagaki A, Ishida T, Ishii T, Komatsu H, Iida S, Ding J, Yonekura K, Takeuchi S, Takatsuka Y, Utsunomiya A, Ueda R. Clinical significance of serum Th1-, Th2- and regulatory T cells-associated cytokines in adult T-cell leukemia/lymphoma: high interleukin-5 and -10 levels are significant unfavorable prognostic factors. Int J Cancer 2006, 118:3054-3061. 10.1002/ijc.21688, 16425276.
    • (2006) Int J Cancer , vol.118 , pp. 3054-3061
    • Inagaki, A.1    Ishida, T.2    Ishii, T.3    Komatsu, H.4    Iida, S.5    Ding, J.6    Yonekura, K.7    Takeuchi, S.8    Takatsuka, Y.9    Utsunomiya, A.10    Ueda, R.11
  • 33
    • 3042838753 scopus 로고    scopus 로고
    • Expression of FoxP3, a key molecule in CD4CD25 regulatory T cells, in adult T-cell leukaemia/lymphoma cells
    • 10.1111/j.1365-2141.2004.04999.x, 15198736
    • Karube K, Ohshima K, Tsuchiya T, Yamaguchi T, Kawano R, Suzumiya J, Utsunomiya A, Harada M, Kikuchi M. Expression of FoxP3, a key molecule in CD4CD25 regulatory T cells, in adult T-cell leukaemia/lymphoma cells. Br J Haematol 2004, 126:81-84. 10.1111/j.1365-2141.2004.04999.x, 15198736.
    • (2004) Br J Haematol , vol.126 , pp. 81-84
    • Karube, K.1    Ohshima, K.2    Tsuchiya, T.3    Yamaguchi, T.4    Kawano, R.5    Suzumiya, J.6    Utsunomiya, A.7    Harada, M.8    Kikuchi, M.9
  • 34
    • 70349883761 scopus 로고    scopus 로고
    • FoxP3+ regulatory T cells are distinct from leukemia cells in HTLV-1-associated adult T-cell leukemia
    • 10.1002/ijc.24664, 19544530
    • Toulza F, Nosaka K, Takiguchi M, Pagliuca T, Mitsuya H, Tanaka Y, Taylor GP, Bangham CR. FoxP3+ regulatory T cells are distinct from leukemia cells in HTLV-1-associated adult T-cell leukemia. Int J Cancer 2009, 125:2375-2382. 10.1002/ijc.24664, 19544530.
    • (2009) Int J Cancer , vol.125 , pp. 2375-2382
    • Toulza, F.1    Nosaka, K.2    Takiguchi, M.3    Pagliuca, T.4    Mitsuya, H.5    Tanaka, Y.6    Taylor, G.P.7    Bangham, C.R.8
  • 36
    • 68349144374 scopus 로고    scopus 로고
    • Abnormally high levels of virus-infected IFN-gamma+ CCR4+ CD4+ CD25+ T cells in a retrovirus-associated neuroinflammatory disorder
    • 10.1371/journal.pone.0006517, 2715877, 19654865
    • Yamano Y, Araya N, Sato T, Utsunomiya A, Azakami K, Hasegawa D, Izumi T, Fujita H, Aratani S, Yagishita N, et al. Abnormally high levels of virus-infected IFN-gamma+ CCR4+ CD4+ CD25+ T cells in a retrovirus-associated neuroinflammatory disorder. PLoS One 2009, 4:e6517. 10.1371/journal.pone.0006517, 2715877, 19654865.
    • (2009) PLoS One , vol.4
    • Yamano, Y.1    Araya, N.2    Sato, T.3    Utsunomiya, A.4    Azakami, K.5    Hasegawa, D.6    Izumi, T.7    Fujita, H.8    Aratani, S.9    Yagishita, N.10
  • 37
    • 18244370760 scopus 로고    scopus 로고
    • Virus-induced dysfunction of CD4+CD25+ T cells in patients with HTLV-I-associated neuroimmunological disease
    • 1087174, 15864353
    • Yamano Y, Takenouchi N, Li HC, Tomaru U, Yao K, Grant CW, Maric DA, Jacobson S. Virus-induced dysfunction of CD4+CD25+ T cells in patients with HTLV-I-associated neuroimmunological disease. J Clin Invest 2005, 115:1361-1368. 1087174, 15864353.
    • (2005) J Clin Invest , vol.115 , pp. 1361-1368
    • Yamano, Y.1    Takenouchi, N.2    Li, H.C.3    Tomaru, U.4    Yao, K.5    Grant, C.W.6    Maric, D.A.7    Jacobson, S.8
  • 38
    • 33646906178 scopus 로고    scopus 로고
    • Reduced Foxp3 protein expression is associated with inflammatory disease during human t lymphotropic virus type 1 Infection
    • 10.1086/503874, 16652285
    • Oh U, Grant C, Griffith C, Fugo K, Takenouchi N, Jacobson S. Reduced Foxp3 protein expression is associated with inflammatory disease during human t lymphotropic virus type 1 Infection. J Infect Dis 2006, 193:1557-1566. 10.1086/503874, 16652285.
    • (2006) J Infect Dis , vol.193 , pp. 1557-1566
    • Oh, U.1    Grant, C.2    Griffith, C.3    Fugo, K.4    Takenouchi, N.5    Jacobson, S.6
  • 39
    • 49449114030 scopus 로고    scopus 로고
    • The frequency of CD127low expressing CD4+CD25high T regulatory cells is inversely correlated with human T lymphotrophic virus type-1 (HTLV-1) proviral load in HTLV-1-infection and HTLV-1-associated myelopathy/tropical spastic paraparesis
    • 10.1186/1471-2172-9-41, 2515103, 18664281
    • Michaelsson J, Barbosa HM, Jordan KA, Chapman JM, Brunialti MK, Neto WK, Nukui Y, Sabino EC, Chieia MA, Oliveira AS, et al. The frequency of CD127low expressing CD4+CD25high T regulatory cells is inversely correlated with human T lymphotrophic virus type-1 (HTLV-1) proviral load in HTLV-1-infection and HTLV-1-associated myelopathy/tropical spastic paraparesis. BMC Immunol 2008, 9:41. 10.1186/1471-2172-9-41, 2515103, 18664281.
    • (2008) BMC Immunol , vol.9 , pp. 41
    • Michaelsson, J.1    Barbosa, H.M.2    Jordan, K.A.3    Chapman, J.M.4    Brunialti, M.K.5    Neto, W.K.6    Nukui, Y.7    Sabino, E.C.8    Chieia, M.A.9    Oliveira, A.S.10
  • 40
    • 49849089833 scopus 로고    scopus 로고
    • Reduced Foxp3 expression with increased cytomegalovirus-specific CTL in HTLV-I-associated myelopathy
    • 10.1016/j.jneuroim.2008.06.005, 18639344
    • Hayashi D, Kubota R, Takenouchi N, Tanaka Y, Hirano R, Takashima H, Osame M, Izumo S, Arimura K. Reduced Foxp3 expression with increased cytomegalovirus-specific CTL in HTLV-I-associated myelopathy. J Neuroimmunol 2008, 200:115-124. 10.1016/j.jneuroim.2008.06.005, 18639344.
    • (2008) J Neuroimmunol , vol.200 , pp. 115-124
    • Hayashi, D.1    Kubota, R.2    Takenouchi, N.3    Tanaka, Y.4    Hirano, R.5    Takashima, H.6    Osame, M.7    Izumo, S.8    Arimura, K.9
  • 41
    • 77956469491 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor reveals distinct requirements for IL-22 and IL-17 production by human T helper cells
    • 10.1002/eji.201040461, 20706985
    • Ramirez JM, Brembilla NC, Sorg O, Chicheportiche R, Matthes T, Dayer JM, Saurat JH, Roosnek E, Chizzolini C. Activation of the aryl hydrocarbon receptor reveals distinct requirements for IL-22 and IL-17 production by human T helper cells. Eur J Immunol 2010, 40:2450-2459. 10.1002/eji.201040461, 20706985.
    • (2010) Eur J Immunol , vol.40 , pp. 2450-2459
    • Ramirez, J.M.1    Brembilla, N.C.2    Sorg, O.3    Chicheportiche, R.4    Matthes, T.5    Dayer, J.M.6    Saurat, J.H.7    Roosnek, E.8    Chizzolini, C.9
  • 43
    • 57049165326 scopus 로고    scopus 로고
    • Elevated pretreatment interleukin-10 serum level is an International Prognostic Score (IPS)-independent risk factor for early treatment failure in advanced stage Hodgkin lymphoma
    • 10.1080/10428190802441339, 19021051
    • Rautert R, Schinkothe T, Franklin J, Weihrauch M, Boll B, Pogge E, Bredenfeld H, Engert A, Diehl V, Re D. Elevated pretreatment interleukin-10 serum level is an International Prognostic Score (IPS)-independent risk factor for early treatment failure in advanced stage Hodgkin lymphoma. Leuk Lymphoma 2008, 49:2091-2098. 10.1080/10428190802441339, 19021051.
    • (2008) Leuk Lymphoma , vol.49 , pp. 2091-2098
    • Rautert, R.1    Schinkothe, T.2    Franklin, J.3    Weihrauch, M.4    Boll, B.5    Pogge, E.6    Bredenfeld, H.7    Engert, A.8    Diehl, V.9    Re, D.10
  • 44
    • 0024408824 scopus 로고
    • Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones
    • 10.1084/jem.170.6.2081, 2189521, 2531194
    • Fiorentino DF, Bond MW, Mosmann TR. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med 1989, 170:2081-2095. 10.1084/jem.170.6.2081, 2189521, 2531194.
    • (1989) J Exp Med , vol.170 , pp. 2081-2095
    • Fiorentino, D.F.1    Bond, M.W.2    Mosmann, T.R.3
  • 45
    • 0027281346 scopus 로고
    • Human interleukin-10 can directly inhibit T-cell growth
    • Taga K, Mostowski H, Tosato G. Human interleukin-10 can directly inhibit T-cell growth. Blood 1993, 81:2964-2971.
    • (1993) Blood , vol.81 , pp. 2964-2971
    • Taga, K.1    Mostowski, H.2    Tosato, G.3
  • 46
    • 35548998271 scopus 로고    scopus 로고
    • IL-2 withdrawal induces HTLV-1 expression through p38 activation in ATL cell lines
    • 10.1016/j.febslet.2007.10.008, 17950728
    • Washiyama M, Nishigaki K, Ahmed N, Kinpara S, Ishii Y, Kanzawa N, Masuda T, Kannagi M. IL-2 withdrawal induces HTLV-1 expression through p38 activation in ATL cell lines. FEBS Lett 2007, 581:5207-5212. 10.1016/j.febslet.2007.10.008, 17950728.
    • (2007) FEBS Lett , vol.581 , pp. 5207-5212
    • Washiyama, M.1    Nishigaki, K.2    Ahmed, N.3    Kinpara, S.4    Ishii, Y.5    Kanzawa, N.6    Masuda, T.7    Kannagi, M.8
  • 47
    • 8644292663 scopus 로고    scopus 로고
    • Enhanced tumorigenesis in HTLV-1 tax-transgenic mice deficient in interferon-gamma
    • 10.1182/blood-2004-01-0266, 15292059
    • Mitra-Kaushik S, Harding J, Hess J, Schreiber R, Ratner L. Enhanced tumorigenesis in HTLV-1 tax-transgenic mice deficient in interferon-gamma. Blood 2004, 104:3305-3311. 10.1182/blood-2004-01-0266, 15292059.
    • (2004) Blood , vol.104 , pp. 3305-3311
    • Mitra-Kaushik, S.1    Harding, J.2    Hess, J.3    Schreiber, R.4    Ratner, L.5
  • 50
    • 0034806874 scopus 로고    scopus 로고
    • Human T cell leukemia virus type I Tax enhances IL-4 gene expression in T cells
    • 10.1002/1521-4141(200109)31:9<2623::AID-IMMU2623>3.0.CO;2-4, 11536160
    • Li-Weber M, Giaisi M, Chlichlia K, Khazaie K, Krammer PH. Human T cell leukemia virus type I Tax enhances IL-4 gene expression in T cells. Eur J Immunol 2001, 31:2623-2632. 10.1002/1521-4141(200109)31:9<2623::AID-IMMU2623>3.0.CO;2-4, 11536160.
    • (2001) Eur J Immunol , vol.31 , pp. 2623-2632
    • Li-Weber, M.1    Giaisi, M.2    Chlichlia, K.3    Khazaie, K.4    Krammer, P.H.5
  • 51
    • 0035883050 scopus 로고    scopus 로고
    • The contribution of NF-kappa B activity to spontaneous proliferation and resistance to apoptosis in human T-cell leukemia virus type 1 Tax-induced tumors
    • 10.1182/blood.V98.4.1200, 11493471
    • Portis T, Harding JC, Ratner L. The contribution of NF-kappa B activity to spontaneous proliferation and resistance to apoptosis in human T-cell leukemia virus type 1 Tax-induced tumors. Blood 2001, 98(4):1200-1208. 10.1182/blood.V98.4.1200, 11493471.
    • (2001) Blood , vol.98 , Issue.4 , pp. 1200-1208
    • Portis, T.1    Harding, J.C.2    Ratner, L.3
  • 52
    • 79959631178 scopus 로고    scopus 로고
    • Controversies in targeted therapy of adult T cell leukemia/lymphoma: ON target or OFF target effects?
    • 3185778, 21994752
    • Nasr R, El Hajj H, Kfoury Y, de Thé H, Hermine O, Bazarbachi A. Controversies in targeted therapy of adult T cell leukemia/lymphoma: ON target or OFF target effects?. Viruses 2011, 3(6):750-769. 3185778, 21994752.
    • (2011) Viruses , vol.3 , Issue.6 , pp. 750-769
    • Nasr, R.1    El Hajj, H.2    Kfoury, Y.3    de Thé, H.4    Hermine, O.5    Bazarbachi, A.6
  • 53
    • 33746589840 scopus 로고    scopus 로고
    • Persistent inhibition of telomerase reprograms adult T-cell leukemia to p53-dependent senescence
    • 10.1182/blood-2006-01-0067, 1895862, 16569765
    • Datta A, Bellon M, Sinha-Datta U, Bazarbachi A, Lepelletier Y, Canioni D, Waldmann TA, Hermine O, Nicot C. Persistent inhibition of telomerase reprograms adult T-cell leukemia to p53-dependent senescence. Blood 2006, 108(3):1021-1029. 10.1182/blood-2006-01-0067, 1895862, 16569765.
    • (2006) Blood , vol.108 , Issue.3 , pp. 1021-1029
    • Datta, A.1    Bellon, M.2    Sinha-Datta, U.3    Bazarbachi, A.4    Lepelletier, Y.5    Canioni, D.6    Waldmann, T.A.7    Hermine, O.8    Nicot, C.9


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