메뉴 건너뛰기




Volumn 11, Issue 1, 2013, Pages

Functional effect of Saffron supplementation and risk genotypes in early age-related macular degeneration: A preliminary report

Author keywords

Age related macular degeneration; Electroretinography; Gene polymorphism; Saffron

Indexed keywords

COMPLEMENT FACTOR H; GENOMIC DNA; NATURAL PRODUCT; SAFFRON; UNCLASSIFIED DRUG;

EID: 84884963753     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-11-228     Document Type: Article
Times cited : (53)

References (56)
  • 2
    • 0033795036 scopus 로고    scopus 로고
    • The role of oxidative stress in the pathogenesis of age-related macular degeneration
    • 10.1016/S0039-6257(00)00140-5, 11033038
    • Beatty S, Koh H, Phil M, Henson D, Boulton M. The role of oxidative stress in the pathogenesis of age-related macular degeneration. Surv Ophthalmol 2000, 45:115-134. 10.1016/S0039-6257(00)00140-5, 11033038.
    • (2000) Surv Ophthalmol , vol.45 , pp. 115-134
    • Beatty, S.1    Koh, H.2    Phil, M.3    Henson, D.4    Boulton, M.5
  • 3
    • 79960671469 scopus 로고    scopus 로고
    • Age related macular degeneration and drusen: neuroinflammation in the retina
    • 10.1016/j.pneurobio.2011.05.011, 21740956
    • Buschini E, Piras A, Nuzzi R, Vercelli A. Age related macular degeneration and drusen: neuroinflammation in the retina. Prog Neurobiol 2011, 95:14-25. 10.1016/j.pneurobio.2011.05.011, 21740956.
    • (2011) Prog Neurobiol , vol.95 , pp. 14-25
    • Buschini, E.1    Piras, A.2    Nuzzi, R.3    Vercelli, A.4
  • 4
    • 77949890579 scopus 로고    scopus 로고
    • Age-related macular degeneration: the molecular link between oxidative damage, tissue-specific inflammation and outer retinal disease: the Proctor lecture
    • 10.1167/iovs.09-4481, 20185837
    • Hollyfield JG. Age-related macular degeneration: the molecular link between oxidative damage, tissue-specific inflammation and outer retinal disease: the Proctor lecture. Invest Ophthalmol Vis Sci 2010, 51:1275-1281. 10.1167/iovs.09-4481, 20185837.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 1275-1281
    • Hollyfield, J.G.1
  • 5
    • 0029836759 scopus 로고    scopus 로고
    • Age-related macular degeneration and smoking. The Rotterdam Study
    • 10.1001/archopht.1996.01100140393005, 8859077
    • Vingerling JR, Hofman A, Grobbee DE, De Jong PT. Age-related macular degeneration and smoking. The Rotterdam Study. Arch Ophthalmol 1996, 114:1193-1196. 10.1001/archopht.1996.01100140393005, 8859077.
    • (1996) Arch Ophthalmol , vol.114 , pp. 1193-1196
    • Vingerling, J.R.1    Hofman, A.2    Grobbee, D.E.3    De Jong, P.T.4
  • 6
    • 0033769628 scopus 로고    scopus 로고
    • The prevalence of age-related maculopathy: the visual impairment project
    • 10.1016/S0161-6420(00)00175-5, 10919916
    • Van Newkirk MR, Nanjan MB, Wang JJ, Mitchell P. The prevalence of age-related maculopathy: the visual impairment project. Ophthalmology 2000, 107:1593-1600. 10.1016/S0161-6420(00)00175-5, 10919916.
    • (2000) Ophthalmology , vol.107 , pp. 1593-1600
    • Van Newkirk, M.R.1    Nanjan, M.B.2    Wang, J.J.3    Mitchell, P.4
  • 9
    • 84863726788 scopus 로고    scopus 로고
    • Consequences of oxidative stress in age-related macular degeneration
    • 10.1016/j.mam.2012.03.009, 3392472, 22510306
    • Jarrett SG, Boulton ME. Consequences of oxidative stress in age-related macular degeneration. Mol Aspects Med 2012, 33:399-417. 10.1016/j.mam.2012.03.009, 3392472, 22510306.
    • (2012) Mol Aspects Med , vol.33 , pp. 399-417
    • Jarrett, S.G.1    Boulton, M.E.2
  • 10
    • 70350238360 scopus 로고    scopus 로고
    • Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration
    • 10.1146/annurev.genom.9.081307.164350, 3469316, 19405847
    • Swaroop A, Chew EY, Rickman CB, Abecasis GR. Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration. Annu Rev Genomics Hum Genet 2009, 10:19-43. 10.1146/annurev.genom.9.081307.164350, 3469316, 19405847.
    • (2009) Annu Rev Genomics Hum Genet , vol.10 , pp. 19-43
    • Swaroop, A.1    Chew, E.Y.2    Rickman, C.B.3    Abecasis, G.R.4
  • 11
    • 0034832029 scopus 로고    scopus 로고
    • An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration
    • 10.1016/S1350-9462(01)00010-6, 11587915
    • Hageman GS, Luthert PJ, Victor Chong NH. An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration. Prog Retin Eye Res 2001, 20:705-732. 10.1016/S1350-9462(01)00010-6, 11587915.
    • (2001) Prog Retin Eye Res , vol.20 , pp. 705-732
    • Hageman, G.S.1    Luthert, P.J.2    Victor Chong, N.H.3
  • 17
    • 79958727628 scopus 로고    scopus 로고
    • Complement in age-related macular degeneration: a focus on function
    • 10.1038/eye.2011.37, 3178140, 21394116
    • Bradley DT, Zipfel PF, Hughes AE. Complement in age-related macular degeneration: a focus on function. Eye 2011, 25:683-693. 10.1038/eye.2011.37, 3178140, 21394116.
    • (2011) Eye , vol.25 , pp. 683-693
    • Bradley, D.T.1    Zipfel, P.F.2    Hughes, A.E.3
  • 18
    • 80052214839 scopus 로고    scopus 로고
    • Risk models for progression to advanced age-related macular degeneration using demographic, environmental, genetic, and ocular factors
    • 10.1016/j.ophtha.2011.04.029, 21959373
    • Seddon JM, Reynolds R, Yu Y, Daly MJ, Rosner B. Risk models for progression to advanced age-related macular degeneration using demographic, environmental, genetic, and ocular factors. Ophthalmology 2011, 118:2203-2211. 10.1016/j.ophtha.2011.04.029, 21959373.
    • (2011) Ophthalmology , vol.118 , pp. 2203-2211
    • Seddon, J.M.1    Reynolds, R.2    Yu, Y.3    Daly, M.J.4    Rosner, B.5
  • 20
    • 17244379811 scopus 로고    scopus 로고
    • Complement factor H polymorphism and age related macular degeneration
    • 10.1126/science.1110189, 15761121
    • Edwards AO, Ritter R, Abel KJ, Manning A, Panhuysen C, Farrer LA. Complement factor H polymorphism and age related macular degeneration. Science 2005, 308:421-424. 10.1126/science.1110189, 15761121.
    • (2005) Science , vol.308 , pp. 421-424
    • Edwards, A.O.1    Ritter, R.2    Abel, K.J.3    Manning, A.4    Panhuysen, C.5    Farrer, L.A.6
  • 22
    • 23944465880 scopus 로고    scopus 로고
    • Susceptibility genes for age-related maculopathy on chromosome 10q26
    • 10.1086/444437, 1226205, 16080115
    • Jakobsdottir J, Conley YP, Weeks DE, Mah TS, Ferrell RE, Gorin MB. Susceptibility genes for age-related maculopathy on chromosome 10q26. Am J Hum Genet 2005, 77:389-407. 10.1086/444437, 1226205, 16080115.
    • (2005) Am J Hum Genet , vol.77 , pp. 389-407
    • Jakobsdottir, J.1    Conley, Y.P.2    Weeks, D.E.3    Mah, T.S.4    Ferrell, R.E.5    Gorin, M.B.6
  • 23
    • 27744462212 scopus 로고    scopus 로고
    • Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk
    • 10.1093/hmg/ddi353, 16174643
    • Rivera A, Fisher SA, Fritsche LG, Keilhauer CN, Lichtner P, Meitinger T, Weber BH. Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk. Hum Mol Genet 2005, 14:3227-3236. 10.1093/hmg/ddi353, 16174643.
    • (2005) Hum Mol Genet , vol.14 , pp. 3227-3236
    • Rivera, A.1    Fisher, S.A.2    Fritsche, L.G.3    Keilhauer, C.N.4    Lichtner, P.5    Meitinger, T.6    Weber, B.H.7
  • 24
    • 0034968528 scopus 로고    scopus 로고
    • Complement factor H: physiology and pathophysiology
    • 10.1055/s-2001-15248, 11446652
    • Zipfel PF. Complement factor H: physiology and pathophysiology. Semin Thromb Hemost 2001, 27:191-199. 10.1055/s-2001-15248, 11446652.
    • (2001) Semin Thromb Hemost , vol.27 , pp. 191-199
    • Zipfel, P.F.1
  • 27
    • 36049042661 scopus 로고    scopus 로고
    • A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration
    • 10.1073/pnas.0703933104, 1987388, 17884985
    • Kanda A, Chen W, Othman M, Branham KE, Brooks M, Khanna R, He S, Lyons R, Abecasis GR, Swaroop A. A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration. Proc Natl Acad Sci USA 2007, 104:16227-16232. 10.1073/pnas.0703933104, 1987388, 17884985.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 16227-16232
    • Kanda, A.1    Chen, W.2    Othman, M.3    Branham, K.E.4    Brooks, M.5    Khanna, R.6    He, S.7    Lyons, R.8    Abecasis, G.R.9    Swaroop, A.10
  • 30
    • 0023277076 scopus 로고
    • Early color vision changes in age-related maculopathy
    • 10.1364/AO.26.001458, 20454343
    • Applegate RA, Adams AJ, Cavender JC, Zisman F. Early color vision changes in age-related maculopathy. Appl Opt 1987, 26:1458-1462. 10.1364/AO.26.001458, 20454343.
    • (1987) Appl Opt , vol.26 , pp. 1458-1462
    • Applegate, R.A.1    Adams, A.J.2    Cavender, J.C.3    Zisman, F.4
  • 31
  • 32
    • 0026660698 scopus 로고
    • Mid-frequency loss of foveal flicker sensitivity in early stages of age-related maculopathy
    • Mayer MJ, Spiegler SJ, Ward B, Glucs A, Kim CB. Mid-frequency loss of foveal flicker sensitivity in early stages of age-related maculopathy. Invest Ophthalmol Vis Sci 1992, 33:3136-3142.
    • (1992) Invest Ophthalmol Vis Sci , vol.33 , pp. 3136-3142
    • Mayer, M.J.1    Spiegler, S.J.2    Ward, B.3    Glucs, A.4    Kim, C.B.5
  • 34
    • 0037224777 scopus 로고    scopus 로고
    • Influence of short-term antioxidant supplementation on macular function in age-related maculopathy: a pilot study including electrophysiologic assessment
    • 10.1016/S0161-6420(02)01547-6, 12511345
    • Falsini B, Piccardi M, Iarossi G, Fadda A, Merendino E, Valentini P. Influence of short-term antioxidant supplementation on macular function in age-related maculopathy: a pilot study including electrophysiologic assessment. Ophthalmology 2003, 110:51-60. 10.1016/S0161-6420(02)01547-6, 12511345.
    • (2003) Ophthalmology , vol.110 , pp. 51-60
    • Falsini, B.1    Piccardi, M.2    Iarossi, G.3    Fadda, A.4    Merendino, E.5    Valentini, P.6
  • 35
    • 0242500290 scopus 로고    scopus 로고
    • Loss of cone function in age-related maculopathy
    • 10.1167/iovs.02-0769, 12714671
    • Phipps JA, Guymer RH, Vingrys AJ. Loss of cone function in age-related maculopathy. Invest Ophthalmol Vis Sci 2003, 44:2277-2283. 10.1167/iovs.02-0769, 12714671.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 2277-2283
    • Phipps, J.A.1    Guymer, R.H.2    Vingrys, A.J.3
  • 36
    • 38549178105 scopus 로고    scopus 로고
    • Carotenoids and antioxidants in age-related maculopathyitalian study: multifocal electroretinogram modifications after 1 year
    • 10.1016/j.ophtha.2007.05.029, 17716735, CARMIS Study Group
    • Parisi V, Tedeschi M, Gallinaro G, Varano M, Saviano S, Piermarocchi S, CARMIS Study Group Carotenoids and antioxidants in age-related maculopathyitalian study: multifocal electroretinogram modifications after 1 year. Ophthalmology 2008, 115:324-333. 10.1016/j.ophtha.2007.05.029, 17716735, CARMIS Study Group.
    • (2008) Ophthalmology , vol.115 , pp. 324-333
    • Parisi, V.1    Tedeschi, M.2    Gallinaro, G.3    Varano, M.4    Saviano, S.5    Piermarocchi, S.6
  • 39
    • 33746733130 scopus 로고    scopus 로고
    • Protective effect of crocin against blue light- and white light-mediated photoreceptor cell death in bovine and primate retinal primary cell culture
    • 10.1167/iovs.05-1621, 16799063
    • Laabich A, Vissvesvaran GP, Lieu KL. Protective effect of crocin against blue light- and white light-mediated photoreceptor cell death in bovine and primate retinal primary cell culture. Invest Ophthalmol Vis Sci 2006, 47:3156-3163. 10.1167/iovs.05-1621, 16799063.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 3156-3163
    • Laabich, A.1    Vissvesvaran, G.P.2    Lieu, K.L.3
  • 40
    • 41949111779 scopus 로고    scopus 로고
    • Saffron supplement maintains morphology and function after exposure to damaging light in mammalian retina
    • 10.1167/iovs.07-0438, 18326756
    • Maccarone R, Di Marco S, Bisti S. Saffron supplement maintains morphology and function after exposure to damaging light in mammalian retina. Invest Ophthalmol Vis Sci 2008, 49:1254-1261. 10.1167/iovs.07-0438, 18326756.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 1254-1261
    • Maccarone, R.1    Di Marco, S.2    Bisti, S.3
  • 41
    • 0034800655 scopus 로고    scopus 로고
    • A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8
    • 1462955, 11594942, Age-Related Eye Disease Study Research Group
    • Age-Related Eye Disease Study Research Group A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol 2001, 119:1417-1436. 1462955, 11594942, Age-Related Eye Disease Study Research Group.
    • (2001) Arch Ophthalmol , vol.119 , pp. 1417-1436
  • 42
    • 0027099648 scopus 로고
    • Temporal frequency dependent adaptation at the level of the outer retina in humans
    • 10.1016/0042-6989(92)90065-Q, 1304081
    • Seiple W, Holopigian K, Greenstein V, Hood DC. Temporal frequency dependent adaptation at the level of the outer retina in humans. Vision Res 1992, 32:2043-2048. 10.1016/0042-6989(92)90065-Q, 1304081.
    • (1992) Vision Res , vol.32 , pp. 2043-2048
    • Seiple, W.1    Holopigian, K.2    Greenstein, V.3    Hood, D.C.4
  • 44
    • 0019404089 scopus 로고
    • The ERG in response to alternating gratings in patients with diseases of the peripheral visual pathway
    • Fiorentini A, Maffei L, Pirchio M, Spinelli D, Porciatti V. The ERG in response to alternating gratings in patients with diseases of the peripheral visual pathway. Invest Ophthalmol Vis Sci 1981, 21:490-493.
    • (1981) Invest Ophthalmol Vis Sci , vol.21 , pp. 490-493
    • Fiorentini, A.1    Maffei, L.2    Pirchio, M.3    Spinelli, D.4    Porciatti, V.5
  • 45
    • 84861904183 scopus 로고    scopus 로고
    • Rapid detection of CFH (p.Y402H) and ARMS2 (p.A69S) polymorphisms in age-related macular degeneration using high-resolution melting analysis
    • Mello E, Falsini B, Zuppi C, Giardina B, Concolino P, Capoluongo E. Rapid detection of CFH (p.Y402H) and ARMS2 (p.A69S) polymorphisms in age-related macular degeneration using high-resolution melting analysis. Clin Chem Lab Med 2012, 50:1031-1034.
    • (2012) Clin Chem Lab Med , vol.50 , pp. 1031-1034
    • Mello, E.1    Falsini, B.2    Zuppi, C.3    Giardina, B.4    Concolino, P.5    Capoluongo, E.6
  • 47
    • 77749307396 scopus 로고    scopus 로고
    • Complement, age-related macular degeneration and a vision of the future
    • 10.1001/archophthalmol.2010.18, 20212207
    • Gehrs KM, Jackson JR, Brown EN, Allikmets R, Hageman GS. Complement, age-related macular degeneration and a vision of the future. Arch Ophthalmol 2010, 128:349-358. 10.1001/archophthalmol.2010.18, 20212207.
    • (2010) Arch Ophthalmol , vol.128 , pp. 349-358
    • Gehrs, K.M.1    Jackson, J.R.2    Brown, E.N.3    Allikmets, R.4    Hageman, G.S.5
  • 48
    • 47249120139 scopus 로고    scopus 로고
    • The spectrum of complement alternative pathway-mediated diseases
    • 10.1111/j.1600-065X.2008.00641.x, 18613844
    • Holers VM. The spectrum of complement alternative pathway-mediated diseases. Immunol Rev 2008, 223:300-316. 10.1111/j.1600-065X.2008.00641.x, 18613844.
    • (2008) Immunol Rev , vol.223 , pp. 300-316
    • Holers, V.M.1
  • 49
    • 79953271804 scopus 로고    scopus 로고
    • Persons with age-related maculopathy risk genotypes and clinically normal eyes have reduced mesopic vision
    • Feigl B, Cao D, Morris CP, Zele AJ. Persons with age-related maculopathy risk genotypes and clinically normal eyes have reduced mesopic vision. Invest Ophthalmol Vis Sci 2011, 52:145-150.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 145-150
    • Feigl, B.1    Cao, D.2    Morris, C.P.3    Zele, A.J.4
  • 50
    • 44349192752 scopus 로고    scopus 로고
    • CFH and LOC387715/ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration
    • 10.1016/j.ophtha.2008.01.036, 18423869
    • Klein ML, Francis PJ, Rosner B, Reynolds R, Hamon SC, Schultz DW, Ott J, Seddon JM. CFH and LOC387715/ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration. Ophthalmology 2008, 115:1019-1025. 10.1016/j.ophtha.2008.01.036, 18423869.
    • (2008) Ophthalmology , vol.115 , pp. 1019-1025
    • Klein, M.L.1    Francis, P.J.2    Rosner, B.3    Reynolds, R.4    Hamon, S.C.5    Schultz, D.W.6    Ott, J.7    Seddon, J.M.8
  • 52
    • 0141746538 scopus 로고    scopus 로고
    • Antinociceptive and anti-inflammatory effects of Crocus sativus L. stigma and petal extracts in mice
    • Hosseinzadeh H, Younesi HM. Antinociceptive and anti-inflammatory effects of Crocus sativus L. stigma and petal extracts in mice. BMC Pharmacol 2002, 15:2-7.
    • (2002) BMC Pharmacol , vol.15 , pp. 2-7
    • Hosseinzadeh, H.1    Younesi, H.M.2
  • 54
    • 77956959692 scopus 로고    scopus 로고
    • Gene and noncoding RNA regulation underlying photoreceptor protection: microarray study of dietary antioxidant saffron and photobiomodulation in rat retina
    • 2932490, 20844572
    • Natoli R, Zhu Y, Valter K, Bisti S, Eells J, Stone J. Gene and noncoding RNA regulation underlying photoreceptor protection: microarray study of dietary antioxidant saffron and photobiomodulation in rat retina. Mol Vis 2010, 16:1801-1822. 2932490, 20844572.
    • (2010) Mol Vis , vol.16 , pp. 1801-1822
    • Natoli, R.1    Zhu, Y.2    Valter, K.3    Bisti, S.4    Eells, J.5    Stone, J.6
  • 55
    • 0035798068 scopus 로고    scopus 로고
    • Crocin suppresses tumor necrosis factor-alpha-induced cell death of neuronally differentiated PC-12 cells
    • 10.1016/S0024-3205(01)01357-1, 11720092
    • Soeda S, Ochiai T, Paopong L, Tanaka H, Shoyama Y, Shimeno H. Crocin suppresses tumor necrosis factor-alpha-induced cell death of neuronally differentiated PC-12 cells. Life Sci 2001, 69:2887-2898. 10.1016/S0024-3205(01)01357-1, 11720092.
    • (2001) Life Sci , vol.69 , pp. 2887-2898
    • Soeda, S.1    Ochiai, T.2    Paopong, L.3    Tanaka, H.4    Shoyama, Y.5    Shimeno, H.6
  • 56
    • 84864443525 scopus 로고    scopus 로고
    • Oral administration of crocetin prevents inner retinal damage induced by N-methyl-d-aspartate in mice
    • 10.1016/j.ejphar.2012.06.035, 22760072
    • Ohno Y, Nakanishi T, Umigai N, Tsuruma K, Shimazawa M, Hara H. Oral administration of crocetin prevents inner retinal damage induced by N-methyl-d-aspartate in mice. Eur J Pharmacol 2012, 690:84-89. 10.1016/j.ejphar.2012.06.035, 22760072.
    • (2012) Eur J Pharmacol , vol.690 , pp. 84-89
    • Ohno, Y.1    Nakanishi, T.2    Umigai, N.3    Tsuruma, K.4    Shimazawa, M.5    Hara, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.