Mitigated cytotoxicity and tremendously enhanced gene transfection efficiency of PEI through facile one-step carbamate modification

Advanced Healthcare Materials

Volumn 2, Issue 10, 2013, Pages 1304-1308

  Yang, Chuan ^a   Cheng, Wei ^a   Teo, Pei Yun ^a   Engler, Amanda C ^b   Coady, Daniel J ^b   Hedrick, James L ^b   Yang, Yi Yan ^a  

^a INSTITUTE OF BIOENGINEERING AND NANOTECHNOLOGY   (Singapore)

^b IBM ALMADEN RESEARCH CENTER   (United States)

Author keywords

Cyclic carbonate; High gene transfection; Negligible toxicity; PEI; Simple click modification

Indexed keywords

MATERIALS; POLYETHERIMIDES;

CYCLIC CARBONATES; GENE TRANSFECTION; SIMPLE CLICK MODIFICATION;

GENES;

AMINE; CARBAMIC ACID; POLYETHYLENEIMINE;

ARTICLE; CHEMICAL COMPOSITION; CHEMICAL MODIFICATION; CONTROLLED STUDY; COST; CYTOTOXICITY; DENSITY; GENE SILENCING; GENE TARGETING; GENE THERAPY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; SYNTHESIS;

CYCLIC CARBONATE; HIGH GENE TRANSFECTION; NEGLIGIBLE TOXICITY; PEI; SIMPLE CLICK MODIFICATION;

CARBAMATES; CELL SURVIVAL; DIOXANES; DNA; HEP G2 CELLS; HUMANS; NANOSTRUCTURES; POLYETHYLENEIMINE; TRANSFECTION;

EID: 84884932769     PISSN: 21922640     EISSN: 21922659     Source Type: Journal    
DOI: 10.1002/adhm.201300046     Document Type: Article

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