Enhanced gene delivery mediated by low molecular weight chitosan/DNA complexes: Effect of pH and serum

Molecular Biotechnology

Volumn 46, Issue 2, 2010, Pages 182-196

  Nimesh, Surendra ^a   Thibault, Marc M ^a   Lavertu, Marc ^a   Buschmann, Michael D ^a  

^a ÉCOLE POLYTECHNIQUE DE MONTRÉAL   (Canada)

Author keywords

Chitosan; Complexes; Cytotoxicity; Transfection; Uptake

Indexed keywords

BIOLOGICAL MECHANISMS; CELLULAR UPTAKE; COMPLEXES; DNA COMPLEX; EFFECT OF PH; FLUORESCENT IMAGING; GENE DELIVERY; HEK293 CELLS; HYDRODYNAMIC DIAMETER; INFLUENCE OF PH; LIPOFECTAMINE; LOW MOLECULAR WEIGHT; TRANSFECTION; TRANSGENE EXPRESSION; UPTAKE;

BODY FLUIDS; CHITIN; CHITOSAN; CYTOTOXICITY; DYNAMIC LIGHT SCATTERING; FLOW CYTOMETRY; GENE THERAPY; GENE TRANSFER;

PH EFFECTS;

CHITOSAN; LIPOFECTAMINE; PLASMID DNA;

ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; CULTURE MEDIUM; CYTOTOXICITY; EMBRYO; FLOW CYTOMETRY; FLUORESCENCE IMAGING; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; HYDRODYNAMICS; IN VITRO GENE TRANSFER; INTERACTIONS WITH DNA; LIGHT SCATTERING; MOLECULAR WEIGHT; NONHUMAN; PH; PHYSICAL CHEMISTRY; SERUM;

ANIMALS; CATTLE; CHITOSAN; DNA; GENE TRANSFER TECHNIQUES; HEK293 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; LUCIFERASES; TRANSFECTION;

EID: 78149466246     PISSN: 10736085     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12033-010-9286-1     Document Type: Article

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