메뉴 건너뛰기




Volumn 127, Issue 1, 2013, Pages 57-65

Arrestin-dependent but G-protein coupled receptor kinase-independent uncoupling of D2-dopamine receptors

Author keywords

arrestin; D2 dopamine receptor; desensitization; G protein coupled receptor kinase; protein kinase C; uncoupling

Indexed keywords

DELTA OPIATE RECEPTOR; DOPAMINE 2 RECEPTOR; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; G PROTEIN COUPLED RECEPTOR KINASE; G PROTEIN GATED INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR3; G PROTEIN GATED INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR3.1; G PROTEIN GATED INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR3.4; PROTEIN KINASE C; RETINA S ANTIGEN; UNCLASSIFIED DRUG;

EID: 84884902187     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12359     Document Type: Article
Times cited : (16)

References (35)
  • 1
    • 0033588094 scopus 로고    scopus 로고
    • Agonist-dependent desensitization of the kappa opioid receptor by G protein receptor kinase and beta-arrestin
    • Appleyard S. M., Celver J., Pineda V., Kovoor A., Wayman G. A., and, Chavkin C., (1999) Agonist-dependent desensitization of the kappa opioid receptor by G protein receptor kinase and beta-arrestin. J. Biol. Chem. 274, 23802-23807.
    • (1999) J. Biol. Chem. , vol.274 , pp. 23802-23807
    • Appleyard, S.M.1    Celver, J.2    Pineda, V.3    Kovoor, A.4    Wayman, G.A.5    Chavkin, C.6
  • 2
    • 1342265799 scopus 로고    scopus 로고
    • Distinct domains of the mu-opioid receptor control uncoupling and internalization
    • Celver J., Xu M., Jin W., Lowe J., and, Chavkin C., (2004) Distinct domains of the mu-opioid receptor control uncoupling and internalization. Mol. Pharmacol. 65, 528-537.
    • (2004) Mol. Pharmacol. , vol.65 , pp. 528-537
    • Celver, J.1    Xu, M.2    Jin, W.3    Lowe, J.4    Chavkin, C.5
  • 3
    • 77954346676 scopus 로고    scopus 로고
    • RGS9-2 mediates specific inhibition of agonist-induced internalization of D2-dopamine receptors
    • Celver J., Sharma M., and, Kovoor A., (2010) RGS9-2 mediates specific inhibition of agonist-induced internalization of D2-dopamine receptors. J. Neurochem. 114, 739-749.
    • (2010) J. Neurochem. , vol.114 , pp. 739-749
    • Celver, J.1    Sharma, M.2    Kovoor, A.3
  • 4
    • 77249103669 scopus 로고    scopus 로고
    • Agonist-induced endocytosis and receptor phosphorylation mediate resensitization of dopamine D2 receptors
    • Cho D., Zheng M., Min C., Ma L., Kurose H., Park J. H., and, Kim K. M., (2010) Agonist-induced endocytosis and receptor phosphorylation mediate resensitization of dopamine D2 receptors. Mol. Endocrinol. 24, 574-586.
    • (2010) Mol. Endocrinol. , vol.24 , pp. 574-586
    • Cho, D.1    Zheng, M.2    Min, C.3    Ma, L.4    Kurose, H.5    Park, J.H.6    Kim, K.M.7
  • 7
    • 84858608294 scopus 로고    scopus 로고
    • Role of receptor-attached phosphates in binding of visual and non-visual arrestins to G protein-coupled receptors
    • Gimenez L. E., Kook S., Vishnivetskiy S. A., Ahmed M. R., Gurevich E. V., and, Gurevich V. V., (2012) Role of receptor-attached phosphates in binding of visual and non-visual arrestins to G protein-coupled receptors. J. Biol. Chem. 287, 9028-9040.
    • (2012) J. Biol. Chem. , vol.287 , pp. 9028-9040
    • Gimenez, L.E.1    Kook, S.2    Vishnivetskiy, S.A.3    Ahmed, M.R.4    Gurevich, E.V.5    Gurevich, V.V.6
  • 8
    • 0842331059 scopus 로고    scopus 로고
    • The molecular acrobatics of arrestin activation
    • Gurevich V. V., and, Gurevich E. V., (2004) The molecular acrobatics of arrestin activation. Trends Pharmacol. Sci. 25, 105-111.
    • (2004) Trends Pharmacol. Sci. , vol.25 , pp. 105-111
    • Gurevich, V.V.1    Gurevich, E.V.2
  • 9
    • 33646414189 scopus 로고    scopus 로고
    • The structural basis of arrestin-mediated regulation of G-protein-coupled receptors
    • Gurevich V. V., and, Gurevich E. V., (2006) The structural basis of arrestin-mediated regulation of G-protein-coupled receptors. Pharmacol. Ther. 110, 465-502.
    • (2006) Pharmacol. Ther. , vol.110 , pp. 465-502
    • Gurevich, V.V.1    Gurevich, E.V.2
  • 11
    • 83555168220 scopus 로고    scopus 로고
    • G protein-coupled receptor kinases: More than just kinases and not only for GPCRs
    • Gurevich E. V., Tesmer J. J., Mushegian A., and, Gurevich V. V., (2012) G protein-coupled receptor kinases: more than just kinases and not only for GPCRs. Pharmacol. Ther. 133, 40-69.
    • (2012) Pharmacol. Ther. , vol.133 , pp. 40-69
    • Gurevich, E.V.1    Tesmer, J.J.2    Mushegian, A.3    Gurevich, V.V.4
  • 12
    • 0033558141 scopus 로고    scopus 로고
    • Sequestration of dopamine D2 receptors depends on coexpression of G-protein-coupled receptor kinases 2 or 5
    • Ito K., Haga T., Lameh J., and, Sadee W., (1999) Sequestration of dopamine D2 receptors depends on coexpression of G-protein-coupled receptor kinases 2 or 5. Eur. J. Biochem. 260, 112-119.
    • (1999) Eur. J. Biochem. , vol.260 , pp. 112-119
    • Ito, K.1    Haga, T.2    Lameh, J.3    Sadee, W.4
  • 13
    • 0033562607 scopus 로고    scopus 로고
    • Distinct domains of the CB1 cannabinoid receptor mediate desensitization and internalization
    • Jin W., Brown S., Roche J. P., Hsieh C., Celver J. P., Kovoor A., Chavkin C., and, Mackie K., (1999) Distinct domains of the CB1 cannabinoid receptor mediate desensitization and internalization. J. Neurosci. 19, 3773-3780.
    • (1999) J. Neurosci. , vol.19 , pp. 3773-3780
    • Jin, W.1    Brown, S.2    Roche, J.P.3    Hsieh, C.4    Celver, J.P.5    Kovoor, A.6    Chavkin, C.7    Mackie, K.8
  • 14
    • 17844410926 scopus 로고    scopus 로고
    • Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors enhances heterodimer formation: A mechanism for receptor cross-talk?
    • Kearn C. S., Blake-Palmer K., Daniel E., Mackie K., and, Glass M., (2005) Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors enhances heterodimer formation: a mechanism for receptor cross-talk? Mol. Pharmacol. 67, 1697-1704.
    • (2005) Mol. Pharmacol. , vol.67 , pp. 1697-1704
    • Kearn, C.S.1    Blake-Palmer, K.2    Daniel, E.3    Mackie, K.4    Glass, M.5
  • 15
    • 0037423307 scopus 로고    scopus 로고
    • N-formyl peptide receptor phosphorylation domains differentially regulate arrestin and agonist affinity
    • Key T. A., Foutz T. D., Gurevich V. V., Sklar L. A., and, Prossnitz E. R., (2003) N-formyl peptide receptor phosphorylation domains differentially regulate arrestin and agonist affinity. J. Biol. Chem. 278, 4041-4047.
    • (2003) J. Biol. Chem. , vol.278 , pp. 4041-4047
    • Key, T.A.1    Foutz, T.D.2    Gurevich, V.V.3    Sklar, L.A.4    Prossnitz, E.R.5
  • 16
    • 0037012076 scopus 로고    scopus 로고
    • Gi Irks GIRKs
    • Kovoor A., and, Lester H. A., (2002) Gi Irks GIRKs. Neuron 33, 6-8.
    • (2002) Neuron , vol.33 , pp. 6-8
    • Kovoor, A.1    Lester, H.A.2
  • 17
    • 0028985595 scopus 로고
    • Agonist-induced desensitization of the mu opioid receptor-coupled potassium channel (GIRK1)
    • Kovoor A., Henry D. J., and, Chavkin C., (1995) Agonist-induced desensitization of the mu opioid receptor-coupled potassium channel (GIRK1). J. Biol. Chem. 270, 589-595.
    • (1995) J. Biol. Chem. , vol.270 , pp. 589-595
    • Kovoor, A.1    Henry, D.J.2    Chavkin, C.3
  • 18
    • 0030736086 scopus 로고    scopus 로고
    • Mu and delta opioid receptors are differentially desensitized by the coexpression of beta-adrenergic receptor kinase 2 and beta-arrestin 2 in xenopus oocytes
    • Kovoor A., Nappey V., Kieffer B. L., and, Chavkin C., (1997) Mu and delta opioid receptors are differentially desensitized by the coexpression of beta-adrenergic receptor kinase 2 and beta-arrestin 2 in xenopus oocytes. J. Biol. Chem. 272, 27605-27611.
    • (1997) J. Biol. Chem. , vol.272 , pp. 27605-27611
    • Kovoor, A.1    Nappey, V.2    Kieffer, B.L.3    Chavkin, C.4
  • 19
    • 58849164925 scopus 로고    scopus 로고
    • A dopamine D2 receptor mutant capable of G protein-mediated signaling but deficient in arrestin binding
    • Lan H., Liu Y., Bell M. I., Gurevich V. V., and, Neve K. A., (2009) A dopamine D2 receptor mutant capable of G protein-mediated signaling but deficient in arrestin binding. Mol. Pharmacol. 75, 113-123.
    • (2009) Mol. Pharmacol. , vol.75 , pp. 113-123
    • Lan, H.1    Liu, Y.2    Bell, M.I.3    Gurevich, V.V.4    Neve, K.A.5
  • 21
    • 0037124061 scopus 로고    scopus 로고
    • Aspartic acid 564 in the third cytoplasmic loop of the luteinizing hormone/choriogonadotropin receptor is crucial for phosphorylation-independent interaction with arrestin2
    • Mukherjee S., Gurevich V. V., Preninger A., Hamm H. E., Bader M. F., Fazleabas A. T., Birnbaumer L., and, Hunzicker-Dunn M., (2002) Aspartic acid 564 in the third cytoplasmic loop of the luteinizing hormone/choriogonadotropin receptor is crucial for phosphorylation-independent interaction with arrestin2. J. Biol. Chem. 277, 17916-17927.
    • (2002) J. Biol. Chem. , vol.277 , pp. 17916-17927
    • Mukherjee, S.1    Gurevich, V.V.2    Preninger, A.3    Hamm, H.E.4    Bader, M.F.5    Fazleabas, A.T.6    Birnbaumer, L.7    Hunzicker-Dunn, M.8
  • 22
    • 10344262615 scopus 로고    scopus 로고
    • Protein kinase C mediates phosphorylation, desensitization, and trafficking of the D2 dopamine receptor
    • Namkung Y., and, Sibley D. R., (2004) Protein kinase C mediates phosphorylation, desensitization, and trafficking of the D2 dopamine receptor. J. Biol. Chem. 279, 49533-49541.
    • (2004) J. Biol. Chem. , vol.279 , pp. 49533-49541
    • Namkung, Y.1    Sibley, D.R.2
  • 23
    • 67649321841 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase-mediated phosphorylation regulates post-endocytic trafficking of the D2 dopamine receptor
    • Namkung Y., Dipace C., Javitch J. A., and, Sibley D. R., (2009a) G protein-coupled receptor kinase-mediated phosphorylation regulates post-endocytic trafficking of the D2 dopamine receptor. J. Biol. Chem. 284, 15038-15051.
    • (2009) J. Biol. Chem. , vol.284 , pp. 15038-15051
    • Namkung, Y.1    Dipace, C.2    Javitch, J.A.3    Sibley, D.R.4
  • 24
    • 71749113078 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase-2 constitutively regulates D2 dopamine receptor expression and signaling independently of receptor phosphorylation
    • Namkung Y., Dipace C., Urizar E., Javitch J. A., and, Sibley D. R., (2009b) G protein-coupled receptor kinase-2 constitutively regulates D2 dopamine receptor expression and signaling independently of receptor phosphorylation. J. Biol. Chem. 284, 34103-34115.
    • (2009) J. Biol. Chem. , vol.284 , pp. 34103-34115
    • Namkung, Y.1    Dipace, C.2    Urizar, E.3    Javitch, J.A.4    Sibley, D.R.5
  • 26
    • 0033600736 scopus 로고    scopus 로고
    • Agonist-induced, G protein-dependent and -independent down-regulation of the mu opioid receptor. The receptor is a direct substrate for protein-tyrosine kinase
    • Pak Y., O'Dowd B. F., Wang J. B., and, George S. R., (1999) Agonist-induced, G protein-dependent and -independent down-regulation of the mu opioid receptor. The receptor is a direct substrate for protein-tyrosine kinase. J. Biol. Chem. 274, 27610-27616.
    • (1999) J. Biol. Chem. , vol.274 , pp. 27610-27616
    • Pak, Y.1    O'Dowd, B.F.2    Wang, J.B.3    George, S.R.4
  • 27
    • 0141814986 scopus 로고    scopus 로고
    • Mu-opioid receptor desensitization: Role of receptor phosphorylation, internalization, and representation
    • Qiu Y., Law P. Y., and, Loh H. H., (2003) Mu-opioid receptor desensitization: role of receptor phosphorylation, internalization, and representation. J. Biol. Chem. 278, 36733-36739.
    • (2003) J. Biol. Chem. , vol.278 , pp. 36733-36739
    • Qiu, Y.1    Law, P.Y.2    Loh, H.H.3
  • 28
    • 0035195752 scopus 로고    scopus 로고
    • Dyskinesia: L-dopa-induced and tardive dyskinesia
    • Rascol O., and, Fabre N., (2001) Dyskinesia: L-dopa-induced and tardive dyskinesia. Clin. Neuropharmacol. 24, 313-323.
    • (2001) Clin. Neuropharmacol. , vol.24 , pp. 313-323
    • Rascol, O.1    Fabre, N.2
  • 29
    • 9644284466 scopus 로고    scopus 로고
    • Internalization of the human CRF receptor 1 is independent of classical phosphorylation sites and of beta-arrestin 1 recruitment
    • Rasmussen T. N., Novak I., and, Nielsen S. M., (2004) Internalization of the human CRF receptor 1 is independent of classical phosphorylation sites and of beta-arrestin 1 recruitment. Eur. J. Biochem. 271, 4366-4374.
    • (2004) Eur. J. Biochem. , vol.271 , pp. 4366-4374
    • Rasmussen, T.N.1    Novak, I.2    Nielsen, S.M.3
  • 30
    • 84855901533 scopus 로고    scopus 로고
    • Molecular mechanism of beta-arrestin-biased agonism at seven-transmembrane receptors
    • Reiter E., Ahn S., Shukla A. K., and, Lefkowitz R. J., (2012) Molecular mechanism of beta-arrestin-biased agonism at seven-transmembrane receptors. Annu. Rev. Pharmacol. Toxicol. 52, 179-197.
    • (2012) Annu. Rev. Pharmacol. Toxicol. , vol.52 , pp. 179-197
    • Reiter, E.1    Ahn, S.2    Shukla, A.K.3    Lefkowitz, R.J.4
  • 31
    • 0141455897 scopus 로고    scopus 로고
    • Understanding antipsychotic 'atypicality': A clinical and pharmacological moving target
    • Remington G., (2003) Understanding antipsychotic 'atypicality': a clinical and pharmacological moving target. J. Psychiatry Neurosci. 28, 275-284.
    • (2003) J. Psychiatry Neurosci. , vol.28 , pp. 275-284
    • Remington, G.1
  • 32
    • 33746575616 scopus 로고    scopus 로고
    • Psychosis pathways converge via D2high dopamine receptors
    • Seeman P., Schwarz J., Chen J. F., et al,. (2006) Psychosis pathways converge via D2high dopamine receptors. Synapse 60, 319-346.
    • (2006) Synapse , vol.60 , pp. 319-346
    • Seeman, P.1    Schwarz, J.2    Chen, J.F.3
  • 33
    • 0035976757 scopus 로고    scopus 로고
    • Divers pathways mediate delta-opioid receptor down regulation within the same cell
    • Shapira M., Keren O., Gafni M., and, Sarne Y., (2001) Divers pathways mediate delta-opioid receptor down regulation within the same cell. Brain Res. Mol. Brain Res. 96, 142-150.
    • (2001) Brain Res. Mol. Brain Res. , vol.96 , pp. 142-150
    • Shapira, M.1    Keren, O.2    Gafni, M.3    Sarne, Y.4
  • 34
    • 79953193734 scopus 로고    scopus 로고
    • Neurotensin triggers dopamine D2 receptor desensitization through a protein kinase C and beta-arrestin1-dependent mechanism
    • Thibault D., Albert P. R., Pineyro G., and, Trudeau L. E., (2011) Neurotensin triggers dopamine D2 receptor desensitization through a protein kinase C and beta-arrestin1-dependent mechanism. J. Biol. Chem. 286, 9174-9184.
    • (2011) J. Biol. Chem. , vol.286 , pp. 9174-9184
    • Thibault, D.1    Albert, P.R.2    Pineyro, G.3    Trudeau, L.E.4
  • 35
    • 0035896001 scopus 로고    scopus 로고
    • Heterologous activation of protein kinase C stimulates phosphorylation of delta-opioid receptor at serine 344, resulting in beta-arrestin- and clathrin-mediated receptor internalization
    • Xiang B., Yu G. H., Guo J., Chen L., Hu W., Pei G., and, Ma L., (2001) Heterologous activation of protein kinase C stimulates phosphorylation of delta-opioid receptor at serine 344, resulting in beta-arrestin- and clathrin-mediated receptor internalization. J. Biol. Chem. 276, 4709-4716.
    • (2001) J. Biol. Chem. , vol.276 , pp. 4709-4716
    • Xiang, B.1    Yu, G.H.2    Guo, J.3    Chen, L.4    Hu, W.5    Pei, G.6    Ma, L.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.