Identification of labile zn sites in drug-target proteins

Journal of the American Chemical Society

Volumn 135, Issue 38, 2013, Pages 14028-14031

  Lee, Yu Ming ^a   Wang, Yi Ting ^b   Duh, Yulander ^b   Yuan, Hanna S ^b   Lim, Carmay ^a,c  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^b INSTITUTE OF MOLECULAR BIOLOGY   (Taiwan)

^c NATIONAL TSING HUA UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG TARGETS; PROTEIN UNFOLDING; THIOLATES;

HYDROGEN BONDS; ZINC;

PROTEINS;

ESTROGEN RECEPTOR; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; ZINC; ZINC FINGER PROTEIN; ZINC ION;

ARTICLE; CONTROLLED STUDY; DNA BINDING; DNA METHYLATION; DRUG TARGETING; ELECTROPHILICITY; HYDROGEN BOND; MOLECULAR MECHANICS; MOLECULAR WEIGHT; NONHUMAN; PROTEIN ANALYSIS; PROTEIN STRUCTURE; PROTEIN TARGETING; PROTEIN UNFOLDING; REACTION ANALYSIS; STATIC ELECTRICITY; ZINC FINGER MOTIF;

2,2'-DIPYRIDYL; CCAAT-ENHANCER-BINDING PROTEINS; DISULFIDES; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; HISTONE DEACETYLASES; HUMANS; PROTEINS; RECOMBINANT PROTEINS; SULFHYDRYL COMPOUNDS; THIRAM; TNF RECEPTOR-ASSOCIATED FACTOR 6; UBIQUITIN-PROTEIN LIGASES; ZINC; ZINC FINGERS;

EID: 84884891743     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja406300c     Document Type: Article

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