How the HIV-1 Nucleocapsid Protein Binds and Destabilises the (-)Primer Binding Site During Reverse Transcription

Journal of Molecular Biology

Volumn 383, Issue 5, 2008, Pages 1112-1128

  Bourbigot, Sarah ^a,b,c   Ramalanjaona, Nick ^a   Boudier, Christian ^a   Salgado, Gilmar F J ^a,b,c   Roques, Bernard P ^d   Mély, Yves ^a   Bouaziz, Serge ^a,b,c   Morellet, Nelly ^a,b,c  

^a CNRS   (France)

^b INSERM   (France)

^c FACULTÉ DES SCIENCES PHARMACEUTIQUES ET BIOLOGIQUES   (France)

^d Lab d'Hyg et de S Publique   (France)

Author keywords

4 (4 dimethylaminophenylazo)benzoic acid; 6 carboxyrhodamine; DABCYL; exchange; exchange spectroscopy; EXSY; FCS; fluorescence correlation spectroscopy; HIV 1; human immunodeficiency virus type 1; human immunodeficiency virus type 1 (HIV 1); isothermal titration calorimetry; ITC; NOE; NOESY; nuclear magnetic resonance (NMR); nuclear Overhauser enhancement; nuclear Overhauser enhancement spectroscopy; nucleocapsid protein (NCp7); PBS; primer binding site (PBS); primer binding site; Rh6G; ROESY; rotating frame Overhauser effect spectroscopy; SL; stem loop>; TOCSY; total correlated spectroscopy

Indexed keywords

NUCLEOCAPSID PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROPHOBICITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; REVERSE TRANSCRIPTION; ZINC FINGER MOTIF;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 53749093357     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2008.08.046     Document Type: Article

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