7,8-dihydroxyflavone suppresses oxidative stress-induced base modification in DNA via induction of the repair enzyme 8-oxoguanine DNA glycosylase-1

BioMed Research International

Volumn 2013, Issue , 2013, Pages

  Kim, Ki Cheon ^a   Lee, In Kyung ^b   Kang, Kyoung Ah ^a   Cha, Ji Won ^a   Cho, Suk Ju ^a   Na, Soo Young ^a   Chae, Sungwook ^c   Kim, Hye Sun ^d   Kim, Suhkmann ^e   Hyun, Jin Won ^a  

^a Jeju National University   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

^c Korea Institute of Oriental Medicine (KIOM)   (South Korea)

^d Seoul National University   (South Korea)

^e Pusan National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

7,8 DIHYDROXYFLAVONE; 8 HYDROXYGUANINE; 8 OXOGUANINE DNA GLYCOSYLASE 1; DNA BASE; HYDROGEN PEROXIDE; MESSENGER RNA; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; TRANSCRIPTION FACTOR MAF; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; 6,7 DIHYDROXYFLAVONE; 6,7-DIHYDROXYFLAVONE; DNA GLYCOSYLTRANSFERASE; FLAVONE DERIVATIVE; OXOGUANINE GLYCOSYLASE 1, HUMAN;

ANIMAL CELL; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DNA MODIFICATION; FIBROBLAST; GENE EXPRESSION; NONHUMAN; OXIDATIVE STRESS; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HAMSTER; HUMAN; LUNG; METABOLISM;

ANIMALS; CRICETINAE; DNA GLYCOSYLASES; FIBROBLASTS; FLAVONES; GENE EXPRESSION REGULATION; HUMANS; HYDROGEN PEROXIDE; LUNG; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 84884859723     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2013/863720     Document Type: Article

References (47)

1. Ravanat J., Berger M., Benard F., Phthalocyanine and naphthalocyanine photosensitized oxidation of 2′-deoxyguanosine: distinct type I and type II products. Photochemistry and Photobiology 1984 39 6 809 814
2. Honda M., Yamada Y., Tomonaga M., Ichinose H., Kamihira S., Correlation of urinary 8-hydroxy-2′-deoxyguanosine (8-OHdG), a biomarker of oxidative DNA damage, and clinical features of hematological disorders: a pilot study. Leukemia Research 2000 24 6 461 468 2-s2.0-0034002547 10.1016/S0145-2126(00) 00006-0 (Pubitemid 30227222)
3. Hyun J. W., Choi J. Y., Zeng H. H., Lee Y., Kim H., Yoon S., Chung M., Leukemic cell line, KG-1 has a functional loss of hOGG1 enzyme due to a point mutation and 8-hydroxydeoxyguanosine can kill KG-1. Oncogene 2000 19 39 4476 4479 2-s2.0-0034648719
4. Hyun J. W., Jung Y. C., Kim H. S., Choi E., Kim J., Yoon B., Yoon S., Lee Y., Choi J., You H., Chung M., 8-Hydroxydeoxyguanosine causes death of human leukemia cells deficient in 8-oxoguanine glycosylase 1 activity by inducing apoptosis. Molecular Cancer Research 2003 1 4 290 299 2-s2.0-12244270357 (Pubitemid 36292614)
5. Kikuchi A., Takeda A., Onodera H., Kimpara T., Hisanaga K., Sato N., Nunomura A., Castellani R. J., Perry G., Smith M. A., Itoyama Y., Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy. Neurobiology of Disease 2002 9 2 244 248 2-s2.0-0036197296 10.1006/nbdi.2002.0466 (Pubitemid 34261218)
6. Matsui M., Nishigori C., Toyokuni S., Takada J., Akaboshi M., Ishikawa M., Imamura S., Miyachi Y., The role of oxidative DNA damage in human arsenic carcinogenesis: detection of 8-hydroxy-2′-deoxyguanosine in arsenic-related Bowen's disease. Journal of Investigative Dermatology 1999 113 1 26 31 2-s2.0-0042771971 10.1046/j.1523-1747.1999.00630.x (Pubitemid 29328154)
7. Sato S., Mizuno Y., Hattori N., Urinary 8-hydroxydeoxyguanosine levels as a biomarker for progression of Parkinson disease. Neurology 2005 64 6 1081 1083 2-s2.0-15244357268 (Pubitemid 40388471)
8. Wu L. L., Chiou C., Chang P., Wu J. T., Urinary 8-OHdG: a marker of oxidative stress to DNA and a risk factor for cancer, atherosclerosis and diabetics. Clinica Chimica Acta 2004 339 1-2 1 9 2-s2.0-0345735389 10.1016/j.cccn.2003.09.010 (Pubitemid 37542453)
9. Halliwell B., Reactive species and antioxidants. Redox biology is a fundamental theme of aerobic life. Plant Physiology 2006 141 2 312 322 2-s2.0-33745662190 10.1104/pp.106.077073 (Pubitemid 43974521)
10. Boiteux S., O'Connor T. R., Lederer F., Gouyette A., Laval J., Homogeneous Escherichia coli FPG protein. A DNA glycosylase which excises imidazole ring-opened purines and nicks DNA at apurinic/apyrimidinic sites. Journal of Biological Chemistry 1990 265 7 3916 3922 2-s2.0-0025240665
11. Krokan H. E., Nilsen H., Skorpen F., Otterlei M., Slupphaug G., Base excision repair of DNA in mammalian cells. FEBS Letters 2000 476 1-2 73 77 2-s2.0-0034733899 10.1016/S0014-5793(00)01674-4 (Pubitemid 30394654)
12. Bogliolo M., Cappelli E., D'Osualdo A., Rossi O., Barbieri O., Kelley M. R., Frosina G., Effect of S. cerevisiae APN1 protein on mammalian DNA base excision repair. Anticancer Research 2003 23 5 3727 3734 2-s2.0-0344010996 (Pubitemid 37474317)
13. de Souza-Pinto N. C., Eide L., Hogue B. A., Thybo T., Stevnsner T., Seeberg E., Klungland A., Bohr V. A., Repair of 8-oxodeoxyguanosine lesions in mitochondrial DNA depends on the oxoguanine DNA glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial DNA of OGG1-defective mice. Cancer Research 2001 61 14 5378 5381 2-s2.0-0035878869 (Pubitemid 32694914)
14. Dhénaut A., Boiteux S., Radicella J. P., Characterization of the hOGG1 promoter and its expression during the cell cycle. Mutation Research 2000 461 2 109 118 2-s2.0-0343353893 10.1016/S0921-8777(00)00042-2
15. Ueta E., Sasabe E., Yang Z., Osaki T., Yamamoto T., Enhancement of apoptotic damage of squamous cell carcinoma cells by inhibition of the mitochondrial DNA repairing system. Cancer Science 2008 99 11 2230 2237 2-s2.0-55449126111 10.1111/j.1349-7006.2008.00918.x
16. Keum Y. S., Regulation of Nrf2-mediated phase II detoxification and anti-oxidant genes. Biomolecules & Therapeutics 2012 20 2 144 151
17. Itoh K., Chiba T., Takahashi S., Ishii T., Igarashi K., Katoh Y., Oyake T., Hayashi N., Satoh K., Hatayama I., Yamamoto M., Nabeshima Y., An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochemical and Biophysical Research Communications 1997 236 2 313 322 2-s2.0-0031577292 10.1006/bbrc.1997.6943 (Pubitemid 27373291)
18. Nakaso K., Yano H., Fukuhara Y., Takeshima T., Wada-Isoe K., Nakashima K., PI3K is a key molecule in the Nrf2-mediated regulation of antioxidative proteins by hemin in human neuroblastoma cells. FEBS Letters 2003 546 2-3 181 184 2-s2.0-0038537298 10.1016/S0014-5793(03)00517-9 (Pubitemid 36782407)
19. Wang L., Chen Y., Sternberg P., Cai J., Essential roles of the PI3 kinase/Akt pathway in regulating Nrf2-dependent antioxidant functions in the RPE. Investigative Ophthalmology and Visual Science 2008 49 4 1671 1678 2-s2.0-45549087514 10.1167/iovs.07-1099
20. Tasdemir D., Kaiser M., Brun R., Yardley V., Schmidt T. J., Tosun F., Rüedi P., Antitrypanosomal and antileishmanial activities of flavonoids and their analogues: in vitro, in vivo, structure-activity relationship, and quantitative structure-activity relationship studies. Antimicrobial Agents and Chemotherapy 2006 50 4 1352 1364 2-s2.0-33645755408 10.1128/AAC.50.4.1352-1364. 2006
21. Zhang R., Kang K. A., Piao M. J., Ko D. O., Wang Z. H., Chang W. Y., You H. J., Lee I. K., Kim B. J., Kang S. S., Hyun J. W., Preventive effect of 7,8-dihydroxyflavone against oxidative stress induced genotoxicity. Biological and Pharmaceutical Bulletin 2009 32 2 166 171 2-s2.0-60749102990 10.1248/bpb.32.166
22. Pryor W. A., Stone K., Zang L., Bermúdez E., Fractionation of aqueous cigarette tar extracts: fractions that contain the tar radical cause DNA damage. Chemical Research in Toxicology 1998 11 5 441 448 2-s2.0-0031748203 10.1021/tx970159y (Pubitemid 28242488)
23. Murray J. I., Whitfield M. L., Trinklein N. D., Myers R. M., Brown P. O., Botstein D., Diverse and specific gene expression responses to stresses in cultured human cells. Molecular Biology of the Cell 2004 15 5 2361 2374 2-s2.0-2342518844 10.1091/mbc.E03-11-0799 (Pubitemid 38580652)
24. Kang K. A., Lee K. H., Chae S., Zhang R., Jung M. S., Lee Y., Kim S. Y., Kim H. S., Joo H. G., Park J. W., Ham Y. M., Lee N. H., Hyun J. W., Eckol isolated from Ecklonia cava attenuates oxidative stress induced cell damage in lung fibroblast cells. FEBS Letters 2005 579 28 6295 6304 2-s2.0-27744511937 10.1016/j.febslet.2005.10.008 (Pubitemid 41612143)
25. Struthers L., Patel R., Clark J., Thomas S., Direct detection of 8-oxodeoxyguanosine and 8-oxoguanine by avidin and its analogues. Analytical Biochemistry 1998 255 1 20 31 2-s2.0-0031984418 10.1006/abio.1997.2354 (Pubitemid 28047615)
26. Livak K. J., Schmittgen T. D., Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method. Methods 2001 25 4 402 408 2-s2.0-0035710746 10.1006/meth.2001.1262 (Pubitemid 34164012)
27. Carmichael J., DeGraff W. G., Gazdar A. F., Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing. Cancer Research 1987 47 4 936 942 2-s2.0-0023130372 (Pubitemid 17027905)
28. Valavanidis A., Vlachogianni T., Fiotakis C., 8-hydroxy-2′- deoxyguanosine (8-OHdG): a critical biomarker of oxidative stress and carcinogenesis. Journal of Environmental Science and Health C 2009 27 2 120 139 2-s2.0-66149088854
29. Fortini P., Pascucci B., Parlanti E., D'Errico M., Simonelli V., Dogliotti E., 8-Oxoguanine DNA damage: at the crossroad of alternative repair pathways. Mutation Research 2003 531 1-2 127 139 2-s2.0-0344154405 10.1016/j.mrfmmm.2003.07.004 (Pubitemid 37456727)
30. Mo J., Xia Y., Wade T. J., Schmitt M., Le X. C., Dang R., Mumford J. L., Chronic arsenic exposure and oxidative stress: OGG1 expression and arsenic exposure, nail selenium, and skin hyperkeratosis in inner Mongolia. Environmental Health Perspectives 2006 114 6 835 841 2-s2.0-33745020070 10.1289/ehp.8723 (Pubitemid 43871730)
31. David S. S., O'Shea V. L., Kundu S., Base-excision repair of oxidative DNA damage. Nature 2007 447 7147 941 950 2-s2.0-34250900982 10.1038/nature05978 (Pubitemid 46975761)
32. Ruchko M. V., Gorodnya O. M., Zuleta A., Pastukh V. M., Gillespie M. N., The DNA glycosylase Ogg1 defends against oxidant-induced mtDNA damage and apoptosis in pulmonary artery endothelial cells. Free Radical Biology and Medicine 2011 50 9 1107 1113 2-s2.0-79953252754 10.1016/j.freeradbiomed.2010.10. 692
33. Liu D., Croteau D. L., Souza-Pinto N., Pitta M., Tian J., Wu C., Jiang H., Mustafa K., Keijzers G., Bohr V. A., Mattson M. P., Evidence that OGG1 glycosylase protects neurons against oxidative DNA damage and cell death under ischemic conditions. Journal of Cerebral Blood Flow and Metabolism 2011 31 2 680 692 2-s2.0-79551649906 10.1038/jcbfm.2010.147
34. Motohashi H., Katsuoka F., Engel J. D., Yamamoto M., Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway. Proceedings of the National Academy of Sciences of the United States of America 2004 101 17 6379 6384 2-s2.0-2342511435 10.1073/pnas.0305902101 (Pubitemid 38585982)
35. McMahon M., Itoh K., Yamamoto M., Hayes J. D., Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression. Journal of Biological Chemistry 2003 278 24 21592 21600 2-s2.0-0037821802 10.1074/jbc.M300931200 (Pubitemid 36792558)
36. Kensler T. W., Wakabayashi N., Biswal S., Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annual Review of Pharmacology and Toxicology 2007 47 89 116 2-s2.0-33847050801 10.1146/annurev.pharmtox.46.120604.141046
37. Sykiotis G. P., Bohmann D., Stress-activated cap"n"collar transcription factors in aging and human disease. Science Signaling 2010 3 112 re3 2-s2.0-77953012548 10.1126/scisignal.3112re3
38. Itoh K., Tong K. I., Yamamoto M., Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles. Free Radical Biology and Medicine 2004 36 10 1208 1213 2-s2.0-1942455887 10.1016/j.freeradbiomed.2004.02.075 (Pubitemid 38526314)
39. Boutten A., Goven D., Artaud-Macari E., Boczkowski J., Bonay M., NRF2 targeting: a promising therapeutic strategy in chronic obstructive pulmonary disease. Trends in Molecular Medicine 2011 17 7 363 371 2-s2.0-79960273488 10.1016/j.molmed.2011.02.006
40. Thannickal V. J., Fanburg B. L., Reactive oxygen species in cell signaling. American Journal of Physiology 2000 279 6 L1005 L1028 2-s2.0-0034533082 (Pubitemid 32009487)
41. Pi J., Qu W., Reece J. M., Kumagai Y., Waalkes M. P., Transcription factor Nrf2 activation by inorganic arsenic in cultured keratinocytes: involvement of hydrogen peroxide. Experimental Cell Research 2003 290 2 234 245 2-s2.0-0142058235 10.1016/S0014-4827(03)00341-0 (Pubitemid 37272168)
42. Lee J. W., Hanson J. M., Chu W. A., Johnson J. A., Phosphatidylinositol 3-kinase, not extracellular signal-regulated kinase, regulates activation of the antioxidant-responsive element in IMR-32 human neuroblastoma cells. Journal of Biological Chemistry 2001 276 23 20011 20016 2-s2.0-0035827505 10.1074/jbc.M100734200
43. Martin D., Rojo A. I., Salinas M., Diaz R., Gallardo G., Alam J., Ruiz De Galarreta C. M., Cuadrado A., Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol. Journal of Biological Chemistry 2004 279 10 8919 8929 2-s2.0-1542335553 10.1074/jbc.M309660200 (Pubitemid 38295953)
44. Surh Y. J., Kundu J. K., Na H. K., Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals. Planta Medica 2008 74 13 1526 1539 2-s2.0-56249106571 10.1055/s-0028-1088302
45. Papaiahgari S., Zhang Q., Kleeberger S. R., Cho H., Reddy S. P., Hyperoxia stimulates an Nrf2-ARE transcriptional response via ROS-EGFR-P13K-Akt/ERK MAP kinase signaling in pulmonary epithelial cells. Antioxidants and Redox Signaling 2006 8 1-2 43 52 2-s2.0-33644649422 10.1089/ars.2006.8.43 (Pubitemid 43324529)
46. Le Belle J. E., Orozco N. M., Paucar A. A., Saxe J. P., Mottahedeh J., Pyle A. D., Wu H., Kornblum H. I., Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner. Cell Stem Cell 2011 8 1 59 71 2-s2.0-78650968492 10.1016/j.stem.2010.11.028
47. Erdogdu Ö., Nathanson D., Sjöholm Å., Nyström T., Zhang Q., Exendin-4 stimulates proliferation of human coronary artery endothelial cells through eNOS-, PKA- and PI3K/Akt-dependent pathways and requires GLP-1 receptor. Molecular and Cellular Endocrinology 2010 325 1-2 26 35 2-s2.0-77954384449 10.1016/j.mce.2010.04.022