메뉴 건너뛰기




Volumn 113, Issue 9, 2013, Pages 2183-2192

Space physiology VI: Exercise, artificial gravity, and countermeasure development for prolonged space flight

Author keywords

Aerobic exercise; Cardiovascular; Fluid shift; ICP; LBNP; Microgravity; Musculoskeletal; Resistive exercise; Vision decrement

Indexed keywords

ANIMAL; CARDIOVASCULAR FUNCTION; EXERCISE; GRAVITY; HUMAN; PHYSIOLOGY; REVIEW; SKELETAL MUSCLE; SPACE FLIGHT; WEIGHTLESSNESS;

EID: 84884816176     PISSN: 14396319     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00421-012-2523-5     Document Type: Review
Times cited : (123)

References (87)
  • 1
    • 0034030333 scopus 로고    scopus 로고
    • Leg-press resistance training during 20 days of 6 degrees head-down-tilt bed rest prevents muscle deconditioning
    • 10879440 10.1007/s004210050648 1:STN:280:DC%2BD3cvntFGjtQ%3D%3D
    • Akima H, Kubo K, Kanehisa H, Suzuki Y, Gunji A, Fukunaga T (2000) Leg-press resistance training during 20 days of 6 degrees head-down-tilt bed rest prevents muscle deconditioning. Eur J Appl Physiol 82:30-38
    • (2000) Eur J Appl Physiol , vol.82 , pp. 30-38
    • Akima, H.1    Kubo, K.2    Kanehisa, H.3    Suzuki, Y.4    Gunji, A.5    Fukunaga, T.6
  • 3
    • 3042700474 scopus 로고    scopus 로고
    • Efficacy of a gravity-independent resistance exercise device as a countermeasure to muscle atrophy during 29-day bed rest
    • 15196095 10.1111/j.1365-201X.2004.01293.x 1:CAS:528:DC%2BD2cXlslSqtr8%3D
    • Alkner BA, Tesch PA (2004) Efficacy of a gravity-independent resistance exercise device as a countermeasure to muscle atrophy during 29-day bed rest. Acta Physiol Scand 181:345-357
    • (2004) Acta Physiol Scand , vol.181 , pp. 345-357
    • Alkner, B.A.1    Tesch, P.A.2
  • 5
    • 27544492516 scopus 로고    scopus 로고
    • Portal vein cross-sectional area and flow and orthostatic tolerance: A 90-day bed rest study
    • 16227458 10.1152/japplphysiol.00331.2005
    • Arbeille PP, Besnard SS, Kerbeci PP, Mohty DM (2005) Portal vein cross-sectional area and flow and orthostatic tolerance: a 90-day bed rest study. J Appl Physiol 99:1853-1857
    • (2005) J Appl Physiol , vol.99 , pp. 1853-1857
    • Arbeille, P.P.1    Besnard, S.S.2    Kerbeci, P.P.3    Mohty, D.M.4
  • 6
    • 57049152316 scopus 로고    scopus 로고
    • Insufficient flow reduction during LBNP in both splanchnic and lower limb areas is associated with orthostatic intolerance after bedrest
    • 18757480 10.1152/ajpheart.509.2008 1:CAS:528:DC%2BD1cXhsVWktb%2FO
    • Arbeille P, Kerbeci P, Mattar L, Shoemaker JK, Hughson R (2008) Insufficient flow reduction during LBNP in both splanchnic and lower limb areas is associated with orthostatic intolerance after bedrest. Am J Physiol Heart Circ Physiol 295:H1846-H1854
    • (2008) Am J Physiol Heart Circ Physiol , vol.295
    • Arbeille, P.1    Kerbeci, P.2    Mattar, L.3    Shoemaker, J.K.4    Hughson, R.5
  • 8
    • 0042924254 scopus 로고    scopus 로고
    • Bone resorption is induced on the second day of bed rest: Results of a controlled crossover trial
    • 12909597 1:CAS:528:DC%2BD3sXnsFCjsb0%3D
    • Baecker N, Tomic A, Mika C, Gotzmann A, Platen P, Gerzer R, Heer M (2003) Bone resorption is induced on the second day of bed rest: results of a controlled crossover trial. J Appl Physiol 95:977-982
    • (2003) J Appl Physiol , vol.95 , pp. 977-982
    • Baecker, N.1    Tomic, A.2    Mika, C.3    Gotzmann, A.4    Platen, P.5    Gerzer, R.6    Heer, M.7
  • 9
    • 84861526722 scopus 로고    scopus 로고
    • Effects of vibration training on bone metabolism: Results from a short-term bed rest study
    • 21894450 10.1007/s00421-011-2137-3 1:CAS:528:DC%2BC38Xls1Sit7c%3D
    • Baecker N, Frings-Meuthen P, Heer M, Mester J, Liphardt AM (2012) Effects of vibration training on bone metabolism: results from a short-term bed rest study. Eur J Appl Physiol 112:1741-1750
    • (2012) Eur J Appl Physiol , vol.112 , pp. 1741-1750
    • Baecker, N.1    Frings-Meuthen, P.2    Heer, M.3    Mester, J.4    Liphardt, A.M.5
  • 11
    • 45149091896 scopus 로고    scopus 로고
    • Diminished mesenteric vaso- and venoconstriction and elevated plasma ANP and BNP with simulated microgravity
    • 18218919 10.1152/japplphysiol.00954.2006 1:CAS:528:DC%2BD1cXmsFemt74%3D
    • Behnke BJ, Zawieja DC, Gashev AA, Ray CA, Delp MD (2008) Diminished mesenteric vaso- and venoconstriction and elevated plasma ANP and BNP with simulated microgravity. J Appl Physiol 104:1273-1280
    • (2008) J Appl Physiol , vol.104 , pp. 1273-1280
    • Behnke, B.J.1    Zawieja, D.C.2    Gashev, A.A.3    Ray, C.A.4    Delp, M.D.5
  • 12
    • 80052671222 scopus 로고    scopus 로고
    • Bone structure and density via HR-pQCT in 60d bed-rest, 2-years recovery with and without countermeasures
    • 21885896 1:STN:280:DC%2BC3Mfgs1yqsA%3D%3D
    • Belavy DL, Beller G, Ritter Z, Felsenberg D (2011) Bone structure and density via HR-pQCT in 60d bed-rest, 2-years recovery with and without countermeasures. J Musculoskelet Neuronal Interact 11:215-226
    • (2011) J Musculoskelet Neuronal Interact , vol.11 , pp. 215-226
    • Belavy, D.L.1    Beller, G.2    Ritter, Z.3    Felsenberg, D.4
  • 13
    • 84155189041 scopus 로고    scopus 로고
    • Resistive vibration exercise during bed-rest reduces motor control changes in the lumbo-pelvic musculature
    • 22018458 10.1016/j.jelekin.2011.09.009
    • Belavy DL, Wilson SJ, Armbrecht G, Rittweger J, Felsenberg D, Richardson CA (2012) Resistive vibration exercise during bed-rest reduces motor control changes in the lumbo-pelvic musculature. J Electromyogr Kinesiol 22(1):21-30
    • (2012) J Electromyogr Kinesiol , vol.22 , Issue.1 , pp. 21-30
    • Belavy, D.L.1    Wilson, S.J.2    Armbrecht, G.3    Rittweger, J.4    Felsenberg, D.5    Richardson, C.A.6
  • 14
    • 33846240336 scopus 로고    scopus 로고
    • Does altered blood flow to bone in microgravity impact on mechanotransduction?
    • 17185808 1:STN:280:DC%2BD28jkslWltg%3D%3D
    • Bloomfield SA (2006) Does altered blood flow to bone in microgravity impact on mechanotransduction? J Musculoskelet Neuronal Interact 6:324-326
    • (2006) J Musculoskelet Neuronal Interact , vol.6 , pp. 324-326
    • Bloomfield, S.A.1
  • 15
    • 0033870432 scopus 로고    scopus 로고
    • Supine lower body negative pressure exercise simulates metabolic and kinetic features of upright exercise
    • 10926650 1:STN:280:DC%2BD3cvjslSntg%3D%3D
    • Boda WL, Watenpaugh DE, Ballard RE, Hargens AR (2000) Supine lower body negative pressure exercise simulates metabolic and kinetic features of upright exercise. J Appl Physiol 89:649-654
    • (2000) J Appl Physiol , vol.89 , pp. 649-654
    • Boda, W.L.1    Watenpaugh, D.E.2    Ballard, R.E.3    Hargens, A.R.4
  • 16
    • 33947719964 scopus 로고    scopus 로고
    • Fundamental questions about genes, inactivity, and chronic diseases
    • Booth FW, Lees SJ (2007) Fundamental questions about genes, inactivity, and chronic diseases. Physiological genomics 28:146-157
    • (2007) Physiological Genomics , vol.2 , pp. 146-157
    • Booth, F.W.1    Lees, S.J.2
  • 17
    • 67650047761 scopus 로고    scopus 로고
    • Artificial gravity as a countermeasure to microgravity: A pilot study examining the effects on knee extensor and plantar flexor muscle groups
    • 19286573 10.1152/japplphysiol.91130.2008 1:CAS:528:DC%2BD1MXovFKqtrY%3D
    • Caiozzo VJ, Haddad F, Lee S, Baker M, Paloski W, Baldwin KM (2009) Artificial gravity as a countermeasure to microgravity: a pilot study examining the effects on knee extensor and plantar flexor muscle groups. J Appl Physiol 107:39-46
    • (2009) J Appl Physiol , vol.107 , pp. 39-46
    • Caiozzo, V.J.1    Haddad, F.2    Lee, S.3    Baker, M.4    Paloski, W.5    Baldwin, K.M.6
  • 18
    • 21644440039 scopus 로고    scopus 로고
    • Exercise within lower body negative pressure partially counteracts lumbar spine deconditioning associated with 28-day bed rest
    • 15761083 10.1152/japplphysiol.01400.2004
    • Cao P, Kimura S, Macias BR, Ueno T, Watenpaugh DE, Hargens AR (2005) Exercise within lower body negative pressure partially counteracts lumbar spine deconditioning associated with 28-day bed rest. J Appl Physiol 99:39-44
    • (2005) J Appl Physiol , vol.99 , pp. 39-44
    • Cao, P.1    Kimura, S.2    Macias, B.R.3    Ueno, T.4    Watenpaugh, D.E.5    Hargens, A.R.6
  • 19
    • 0034493130 scopus 로고    scopus 로고
    • Alterations in skeletal perfusion with simulated microgravity: A possible mechanism for bone remodeling
    • 10956349 1:STN:280:DC%2BD3cvpsF2jsA%3D%3D
    • Colleran PN, Wilkerson MK, Bloomfield SA, Suva LJ, Turner RT, Delp MD (2000) Alterations in skeletal perfusion with simulated microgravity: a possible mechanism for bone remodeling. J Appl Physiol 89:1046-1054
    • (2000) J Appl Physiol , vol.89 , pp. 1046-1054
    • Colleran, P.N.1    Wilkerson, M.K.2    Bloomfield, S.A.3    Suva, L.J.4    Turner, R.T.5    Delp, M.D.6
  • 20
    • 0000148137 scopus 로고    scopus 로고
    • Exercise and adaptation to microgravity environments
    • Convertino VA (1996) Exercise and adaptation to microgravity environments. Handbook of physiology, pp 815-843
    • (1996) Handbook of Physiology , pp. 815-843
    • Convertino, V.A.1
  • 22
    • 0032964686 scopus 로고    scopus 로고
    • Intra-ocular pressure changes during maximal isometric contraction: Does this reflect intra-cranial pressure or retinal venous pressure?
    • 10319330 1:STN:280:DyaK1M3lt1yrug%3D%3D
    • Dickerman RD, Smith GH, Langham-Roof L, McConathy WJ, East JW, Smith AB (1999) Intra-ocular pressure changes during maximal isometric contraction: does this reflect intra-cranial pressure or retinal venous pressure? Neurol Res 21:243-246
    • (1999) Neurol Res , vol.21 , pp. 243-246
    • Dickerman, R.D.1    Smith, G.H.2    Langham-Roof, L.3    McConathy, W.J.4    East, J.W.5    Smith, A.B.6
  • 23
    • 34447513739 scopus 로고    scopus 로고
    • Plasma and blood volume in space
    • 17630598 10.1097/MAJ.0b013e318065b89b
    • Diedrich A, Paranjape SY, Robertson D (2007) Plasma and blood volume in space. Am J Med Sci 334:80-85
    • (2007) Am J Med Sci , vol.334 , pp. 80-85
    • Diedrich, A.1    Paranjape, S.Y.2    Robertson, D.3
  • 25
    • 0029964564 scopus 로고    scopus 로고
    • Prolonged bed rest decreases skeletal muscle and whole body protein synthesis
    • 8928769 1:CAS:528:DyaK28Xis1enu7s%3D
    • Ferrando AA, Lane HW, Stuart CA, Davis-Street J, Wolfe RR (1996) Prolonged bed rest decreases skeletal muscle and whole body protein synthesis. Am J Physiol 270:E627-E633
    • (1996) Am J Physiol , vol.270
    • Ferrando, A.A.1    Lane, H.W.2    Stuart, C.A.3    Davis-Street, J.4    Wolfe, R.R.5
  • 26
    • 0031002537 scopus 로고    scopus 로고
    • Resistance exercise maintains skeletal muscle protein synthesis during bed rest
    • 9074967 1:STN:280:DyaK2s3ivV2ksg%3D%3D
    • Ferrando AA, Tipton KD, Bamman MM, Wolfe RR (1997) Resistance exercise maintains skeletal muscle protein synthesis during bed rest. J Appl Physiol 82:807-810
    • (1997) J Appl Physiol , vol.82 , pp. 807-810
    • Ferrando, A.A.1    Tipton, K.D.2    Bamman, M.M.3    Wolfe, R.R.4
  • 29
    • 79959902659 scopus 로고    scopus 로고
    • American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: Guidance for prescribing exercise
    • 21694556 10.1249/MSS.0b013e318213fefb
    • Garber CE, Blissmer B, Deschenes MR, Franklin BA, Lamonte MJ, Lee IM, Nieman DC, Swain DP (2011) American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Med Sci Sports Exerc 43:1334-1359
    • (2011) Med Sci Sports Exerc , vol.43 , pp. 1334-1359
    • Garber, C.E.1    Blissmer, B.2    Deschenes, M.R.3    Franklin, B.A.4    Lamonte, M.J.5    Lee, I.M.6    Nieman, D.C.7    Swain, D.P.8
  • 30
    • 33750458695 scopus 로고    scopus 로고
    • Gravity replacement during running in simulated microgravity
    • 17086763
    • Genc KO, Mandes VE, Cavanagh PR (2006) Gravity replacement during running in simulated microgravity. Aviat Space Environ Med 77:1117-1124
    • (2006) Aviat Space Environ Med , vol.77 , pp. 1117-1124
    • Genc, K.O.1    Mandes, V.E.2    Cavanagh, P.R.3
  • 31
    • 3043001603 scopus 로고
    • Skylab 4 Crew Observations
    • Johnston RS, F. DL (eds) (NASA SP-377), Washington D.C.
    • Gibson EG (1977) Skylab 4 Crew Observations. In: Johnston RS, F. DL (eds) Biomedical results from skylab (NASA SP-377), Washington D.C., pp 22-26
    • (1977) Biomedical Results from Skylab , pp. 22-26
    • Gibson, E.G.1
  • 34
    • 35748941921 scopus 로고    scopus 로고
    • Role of low energy expenditure and sitting in obesity, metabolic syndrome, type 2 diabetes, and cardiovascular disease
    • 17827399 10.2337/db07-0882 1:CAS:528:DC%2BD2sXhtlWitL7F
    • Hamilton MT, Hamilton DG, Zderic TW (2007) Role of low energy expenditure and sitting in obesity, metabolic syndrome, type 2 diabetes, and cardiovascular disease. Diabetes 56:2655-2667
    • (2007) Diabetes , vol.56 , pp. 2655-2667
    • Hamilton, M.T.1    Hamilton, D.G.2    Zderic, T.W.3
  • 35
    • 0019446352 scopus 로고
    • Normal transcapillary pressures in human skeletal muscle and subcutaneous tissues
    • 7321903 10.1016/0026-2862(81)90087-X 1:STN:280:DyaL387gtlaktw%3D%3D
    • Hargens AR, Cologne JB, Menninger FJ, Hogan JS, Tucker BJ, Peters RM (1981) Normal transcapillary pressures in human skeletal muscle and subcutaneous tissues. Microvasc Res 22:177-189
    • (1981) Microvasc Res , vol.22 , pp. 177-189
    • Hargens, A.R.1    Cologne, J.B.2    Menninger, F.J.3    Hogan, J.S.4    Tucker, B.J.5    Peters, R.M.6
  • 37
    • 75549087687 scopus 로고    scopus 로고
    • Cardiovascular adaptations, fluid shifts, and countermeasures related to space flight
    • 19615471 10.1016/j.resp.2009.07.005
    • Hargens AR, Richardson S (2009) Cardiovascular adaptations, fluid shifts, and countermeasures related to space flight. Respir Physiol Neurobiol 169(Suppl 1):S30-S33
    • (2009) Respir Physiol Neurobiol , vol.169 , Issue.SUPPL. 1
    • Hargens, A.R.1    Richardson, S.2
  • 38
    • 83655203041 scopus 로고    scopus 로고
    • Brief daily exposure to low intensity vibration mitigates the degradation of the intervertebral disc in a frequency-specific manner
    • 21960658 10.1152/japplphysiol.00846.2011
    • Holguin N, Uzer G, Chiang FP, Rubin CT, Judex S (2011) Brief daily exposure to low intensity vibration mitigates the degradation of the intervertebral disc in a frequency-specific manner. J Appl Physiol 111(6):1846-1853
    • (2011) J Appl Physiol , vol.111 , Issue.6 , pp. 1846-1853
    • Holguin, N.1    Uzer, G.2    Chiang, F.P.3    Rubin, C.T.4    Judex, S.5
  • 39
    • 0035845202 scopus 로고    scopus 로고
    • Usefulness of daily +2Gz load as a countermeasure against physiological problems during weightlessness
    • 11669112 10.1016/S0094-5765(01)00101-1 1:STN:280:DC%2BD3Mrms1KgtA%3D%3D
    • Iwasaki KI, Sasaki T, Hirayanagi K, Yajima K (2001) Usefulness of daily +2Gz load as a countermeasure against physiological problems during weightlessness. Acta Astronaut 49:227-235
    • (2001) Acta Astronaut , vol.49 , pp. 227-235
    • Iwasaki, K.I.1    Sasaki, T.2    Hirayanagi, K.3    Yajima, K.4
  • 40
    • 19944380166 scopus 로고    scopus 로고
    • Effectiveness of centrifuge-induced artificial gravity with ergometric exercise as a countermeasure during simulated microgravity exposure in humans
    • 16010754 10.1016/j.actaastro.2005.03.013
    • Iwase S (2005) Effectiveness of centrifuge-induced artificial gravity with ergometric exercise as a countermeasure during simulated microgravity exposure in humans. Acta Astronaut 57:75-80
    • (2005) Acta Astronaut , vol.57 , pp. 75-80
    • Iwase, S.1
  • 43
    • 0019084635 scopus 로고
    • Blood pressure and oxygenation in different cardiovascular compartments of a normal man during postural exposures
    • 7213270 1:STN:280:DyaL3M7lvFyhuw%3D%3D
    • Katkov VE, Chestukhin VV (1980) Blood pressure and oxygenation in different cardiovascular compartments of a normal man during postural exposures. Aviat Space Environ Med 51:1234-1242
    • (1980) Aviat Space Environ Med , vol.51 , pp. 1234-1242
    • Katkov, V.E.1    Chestukhin, V.V.2
  • 44
    • 0027268267 scopus 로고
    • Fluid shifts into and out of superficial tissues under microgravity and terrestrial conditions
    • 8241717 10.1007/BF00209721 1:STN:280:DyaK2c%2FmtVKhug%3D%3D
    • Kirsch KA, Baartz FJ, Gunga HC, Rocker L (1993) Fluid shifts into and out of superficial tissues under microgravity and terrestrial conditions. Clin Investig 71:687-689
    • (1993) Clin Investig , vol.71 , pp. 687-689
    • Kirsch, K.A.1    Baartz, F.J.2    Gunga, H.C.3    Rocker, L.4
  • 45
    • 0029380330 scopus 로고
    • Countermeasure of the negative effects of weightlessness on physical systems in long-term space flights
    • 11541002 10.1016/0094-5765(95)00156-5 1:STN:280:DC%2BD3MnlvFGktg%3D%3D
    • Kozlovskaya IB, Grigoriev AI, Stepantzov VI (1995) Countermeasure of the negative effects of weightlessness on physical systems in long-term space flights. Acta Astronaut 36:661-668
    • (1995) Acta Astronaut , vol.36 , pp. 661-668
    • Kozlovskaya, I.B.1    Grigoriev, A.I.2    Stepantzov, V.I.3
  • 48
    • 0030785585 scopus 로고    scopus 로고
    • Upright exercise or supine lower body negative pressure exercise maintains exercise responses after bed rest
    • 9243488 10.1097/00005768-199707000-00008 1:STN:280:DyaK2szoslCmtw%3D%3D
    • Lee SM, Bennett BS, Hargens AR, Watenpaugh DE, Ballard RE, Murthy G, Ford SR, Fortney SM (1997) Upright exercise or supine lower body negative pressure exercise maintains exercise responses after bed rest. Med Sci Sports Exerc 29:892-900
    • (1997) Med Sci Sports Exerc , vol.29 , pp. 892-900
    • Lee, S.M.1    Bennett, B.S.2    Hargens, A.R.3    Watenpaugh, D.E.4    Ballard, R.E.5    Murthy, G.6    Ford, S.R.7    Fortney, S.M.8
  • 50
    • 64349084017 scopus 로고    scopus 로고
    • LBNP exercise protects aerobic capacity and sprint speed of female twins during 30 days of bed rest
    • 19112155 10.1152/japplphysiol.91502.2008
    • Lee SM, Schneider SM, Boda WL, Watenpaugh DE, Macias BR, Meyer RS, Hargens AR (2009) LBNP exercise protects aerobic capacity and sprint speed of female twins during 30 days of bed rest. J Appl Physiol 106:919-928
    • (2009) J Appl Physiol , vol.106 , pp. 919-928
    • Lee, S.M.1    Schneider, S.M.2    Boda, W.L.3    Watenpaugh, D.E.4    Macias, B.R.5    Meyer, R.S.6    Hargens, A.R.7
  • 51
    • 0030854092 scopus 로고    scopus 로고
    • Cardiac atrophy after bed-rest deconditioning: A nonneural mechanism for orthostatic intolerance
    • 9244220 10.1161/01.CIR.96.2.517 1:STN:280:DyaK2szos1eksw%3D%3D
    • Levine BD, Zuckerman JH, Pawelczyk JA (1997) Cardiac atrophy after bed-rest deconditioning: a nonneural mechanism for orthostatic intolerance. Circulation 96:517-525
    • (1997) Circulation , vol.96 , pp. 517-525
    • Levine, B.D.1    Zuckerman, J.H.2    Pawelczyk, J.A.3
  • 52
    • 0027501854 scopus 로고
    • Changes in markers of bone formation and resorption in a bed rest model of weightlessness
    • 10.1002/jbmr.5650081204 1:STN:280:DyaK2c7js1Wnug%3D%3D
    • Lueken SA, Arnaud SB, Taylor AK, Baylink DJ (1993) Changes in markers of bone formation and resorption in a bed rest model of weightlessness. J Bone Miner Res: Off J Am Soc Bone Miner Res 8:1433-1438
    • (1993) J Bone Miner Res: Off J Am Soc Bone Miner Res , vol.8 , pp. 1433-1438
    • Lueken, S.A.1    Arnaud, S.B.2    Taylor, A.K.3    Baylink, D.J.4
  • 53
    • 0021839908 scopus 로고
    • Arterial blood pressure response to heavy resistance exercise
    • 3980383 1:STN:280:DyaL2M7lslejsA%3D%3D
    • MacDougall JD, Tuxen D, Sale DG, Moroz JR, Sutton JR (1985) Arterial blood pressure response to heavy resistance exercise. J Appl Physiol 58:785-790
    • (1985) J Appl Physiol , vol.58 , pp. 785-790
    • Macdougall, J.D.1    Tuxen, D.2    Sale, D.G.3    Moroz, J.R.4    Sutton, J.R.5
  • 54
    • 34447540156 scopus 로고    scopus 로고
    • LBNP treadmill exercise maintains spine function and muscle strength in identical twins during 28-day simulated microgravity
    • 17395762 10.1152/japplphysiol.00541.2006
    • Macias BR, Cao P, Watenpaugh DE, Hargens AR (2007) LBNP treadmill exercise maintains spine function and muscle strength in identical twins during 28-day simulated microgravity. J Appl Physiol 102:2274-2278
    • (2007) J Appl Physiol , vol.102 , pp. 2274-2278
    • Macias, B.R.1    Cao, P.2    Watenpaugh, D.E.3    Hargens, A.R.4
  • 57
    • 79954588007 scopus 로고    scopus 로고
    • Differential atrophy of the postero-lateral hip musculature during prolonged bedrest and the influence of exercise countermeasures
    • 21233337 10.1152/japplphysiol.01105.2010
    • Miokovic T, Armbrecht G, Felsenberg D, Belavy DL (2011) Differential atrophy of the postero-lateral hip musculature during prolonged bedrest and the influence of exercise countermeasures. J Appl Physiol 110:926-934
    • (2011) J Appl Physiol , vol.110 , pp. 926-934
    • Miokovic, T.1    Armbrecht, G.2    Felsenberg, D.3    Belavy, D.L.4
  • 58
    • 33744507639 scopus 로고    scopus 로고
    • Renal stone risk in a simulated microgravity environment: Impact of treadmill exercise with lower body negative pressure
    • 16753386 10.1016/S0022-5347(06)00572-6
    • Monga M, Macias B, Groppo E, Kostelec M, Hargens A (2006) Renal stone risk in a simulated microgravity environment: impact of treadmill exercise with lower body negative pressure. J Urol 176:127-131
    • (2006) J Urol , vol.176 , pp. 127-131
    • Monga, M.1    Macias, B.2    Groppo, E.3    Kostelec, M.4    Hargens, A.5
  • 59
    • 75049083878 scopus 로고    scopus 로고
    • Cardiovascular exercise in the US space program: Past, present and future
    • Moore AD, Lee SMC, Stenger MB, Platts SH (2010) Cardiovascular exercise in the U.S. space program: past, present and future. Acta astronautica 66:974-978
    • (2010) Acta Astronautica , vol.66 , pp. 974-978
    • Moore, A.D.1    Lee, S.M.C.2    Stenger, M.B.3    Platts, S.H.4
  • 60
    • 33746587438 scopus 로고    scopus 로고
    • Strength, size and activation of knee extensors followed during 8 weeks of horizontal bed rest and the influence of a countermeasure
    • 16786354 10.1007/s00421-006-0241-6 1:STN:280:DC%2BD28vkvFGltA%3D%3D
    • Mulder ER, Stegeman DF, Gerrits KH, Paalman MI, Rittweger J, Felsenberg D, de Haan A (2006) Strength, size and activation of knee extensors followed during 8 weeks of horizontal bed rest and the influence of a countermeasure. Eur J Appl Physiol 97:706-715
    • (2006) Eur J Appl Physiol , vol.97 , pp. 706-715
    • Mulder, E.R.1    Stegeman, D.F.2    Gerrits, K.H.3    Paalman, M.I.4    Rittweger, J.5    Felsenberg, D.6    De Haan, A.7
  • 62
    • 0026342906 scopus 로고
    • Transcapillary fluid shifts in tissues of the head and neck during and after simulated microgravity
    • 1778948 1:STN:280:DyaK387jvVGntg%3D%3D
    • Parazynski SE, Hargens AR, Tucker B, Aratow M, Styf J, Crenshaw A (1991) Transcapillary fluid shifts in tissues of the head and neck during and after simulated microgravity. J Appl Physiol 71:2469-2475
    • (1991) J Appl Physiol , vol.71 , pp. 2469-2475
    • Parazynski, S.E.1    Hargens, A.R.2    Tucker, B.3    Aratow, M.4    Styf, J.5    Crenshaw, A.6
  • 63
    • 34548263096 scopus 로고    scopus 로고
    • From space to Earth: Advances in human physiology from 20 years of bed rest studies (1986-2006)
    • Pavy-Le Traon A, Heer M, Narici MV, Rittweger J, Vernikos J (2007) From space to Earth: advances in human physiology from 20 years of bed rest studies (1986-2006). Eur J Appl Physiol 101:143-194
    • (2007) Eur J Appl Physiol , vol.101 , pp. 143-194
    • Pavy-Le Traon, A.1    Heer, M.2    Narici, M.V.3    Rittweger, J.4    Vernikos, J.5
  • 64
    • 33745833959 scopus 로고    scopus 로고
    • Endothelium-dependent vasodilation of cerebral arteries is altered with simulated microgravity through nitric oxide synthase and EDHF mechanisms
    • 16627679 10.1152/japplphysiol.00941.2005 1:CAS:528:DC%2BD28XnsFWjtr0%3D
    • Prisby RD, Wilkerson MK, Sokoya EM, Bryan RM Jr, Wilson E, Delp MD (2006) Endothelium-dependent vasodilation of cerebral arteries is altered with simulated microgravity through nitric oxide synthase and EDHF mechanisms. J Appl Physiol 101:348-353
    • (2006) J Appl Physiol , vol.101 , pp. 348-353
    • Prisby, R.D.1    Wilkerson, M.K.2    Sokoya, E.M.3    Bryan, Jr.R.M.4    Wilson, E.5    Delp, M.D.6
  • 65
    • 85014385026 scopus 로고    scopus 로고
    • Flight Surgeon Perspective: Gaps in human health, performance, and safety
    • National Research Council, Washington, D.C
    • Polk JD (2009) Flight Surgeon Perspective: Gaps in human health, performance, and safety. In: Committee of the decadal survey on biological and physical sciences in space. National Research Council, Washington, D.C
    • (2009) Committee of the Decadal Survey on Biological and Physical Sciences in Space
    • Polk, J.D.1
  • 66
    • 22544478796 scopus 로고    scopus 로고
    • The negative regulation of red cell mass by neocytolysis: Physiologic and pathophysiologic manifestations
    • 10.1159/000087234 1:CAS:528:DC%2BD2MXmtlGrtrg%3D
    • Rice L, Alfrey CP (2005) The negative regulation of red cell mass by neocytolysis: physiologic and pathophysiologic manifestations. Cell Physiol Biochem: Int J Exp Cell Physiol Biochem Pharmacol 15:245-250
    • (2005) Cell Physiol Biochem: Int J Exp Cell Physiol Biochem Pharmacol , vol.15 , pp. 245-250
    • Rice, L.1    Alfrey, C.P.2
  • 69
    • 73449087626 scopus 로고    scopus 로고
    • WISE-2005: Exercise and nutrition countermeasures for upright VO2pk during bed rest
    • 19915502 10.1249/MSS.0b013e3181aa04e5
    • Schneider SM, Lee SM, Macias BR, Watenpaugh DE, Hargens AR (2009) WISE-2005: exercise and nutrition countermeasures for upright VO2pk during bed rest. Med Sci Sports Exerc 41:2165-2176
    • (2009) Med Sci Sports Exerc , vol.41 , pp. 2165-2176
    • Schneider, S.M.1    Lee, S.M.2    Macias, B.R.3    Watenpaugh, D.E.4    Hargens, A.R.5
  • 70
  • 71
    • 14944340214 scopus 로고    scopus 로고
    • The nutritional status of astronauts is altered after long-term space flight aboard the International Space Station
    • 15735075 1:CAS:528:DC%2BD2MXit12ntr8%3D
    • Smith SM, Zwart SR, Block G, Rice BL, Davis-Street JE (2005) The nutritional status of astronauts is altered after long-term space flight aboard the International Space Station. J Nutr 135:437-443
    • (2005) J Nutr , vol.135 , pp. 437-443
    • Smith, S.M.1    Zwart, S.R.2    Block, G.3    Rice, B.L.4    Davis-Street, J.E.5
  • 72
    • 0033000338 scopus 로고    scopus 로고
    • Protein kinetics during and after long-duration spaceflight on MIR
    • 10362613 1:CAS:528:DyaK1MXktlSqsbc%3D
    • Stein TP, Leskiw MJ, Schluter MD, Donaldson MR, Larina I (1999a) Protein kinetics during and after long-duration spaceflight on MIR. Am J Physiol 276:E1014-E1021
    • (1999) Am J Physiol , vol.276
    • Stein, T.P.1    Leskiw, M.J.2    Schluter, M.D.3    Donaldson, M.R.4    Larina, I.5
  • 75
    • 0034971330 scopus 로고    scopus 로고
    • Comparison of a space shuttle flight (STS-78) and bed rest on human muscle function
    • 11408413 1:STN:280:DC%2BD3MzksFCrsw%3D%3D
    • Trappe SW, Trappe TA, Lee GA, Widrick JJ, Costill DL, Fitts RH (2001) Comparison of a space shuttle flight (STS-78) and bed rest on human muscle function. J Appl Physiol 91:57-64
    • (2001) J Appl Physiol , vol.91 , pp. 57-64
    • Trappe, S.W.1    Trappe, T.A.2    Lee, G.A.3    Widrick, J.J.4    Costill, D.L.5    Fitts, R.H.6
  • 76
    • 3042695007 scopus 로고    scopus 로고
    • Human single muscle fibre function with 84 day bed-rest and resistance exercise
    • 15064323 10.1113/jphysiol.2004.062166 1:CAS:528:DC%2BD2cXkvFOhs7Y%3D
    • Trappe S, Trappe T, Gallagher P, Harber M, Alkner B, Tesch P (2004) Human single muscle fibre function with 84 day bed-rest and resistance exercise. J Physiol 557:501-513
    • (2004) J Physiol , vol.557 , pp. 501-513
    • Trappe, S.1    Trappe, T.2    Gallagher, P.3    Harber, M.4    Alkner, B.5    Tesch, P.6
  • 77
    • 35348931000 scopus 로고    scopus 로고
    • Single muscle fiber function with concurrent exercise or nutrition countermeasures during 60 days of bed rest in women
    • 17641219 10.1152/japplphysiol.00560.2007
    • Trappe S, Creer A, Slivka D, Minchev K, Trappe T (2007) Single muscle fiber function with concurrent exercise or nutrition countermeasures during 60 days of bed rest in women. J Appl Physiol 103:1242-1250
    • (2007) J Appl Physiol , vol.103 , pp. 1242-1250
    • Trappe, S.1    Creer, A.2    Slivka, D.3    Minchev, K.4    Trappe, T.5
  • 78
    • 40449097564 scopus 로고    scopus 로고
    • Human soleus single muscle fiber function with exercise or nutrition countermeasures during 60 days of bed rest
    • 18094071 10.1152/ajpregu.00761.2007 1:CAS:528:DC%2BD1cXjsFylsro%3D
    • Trappe S, Creer A, Minchev K, Slivka D, Louis E, Luden N, Trappe T (2008) Human soleus single muscle fiber function with exercise or nutrition countermeasures during 60 days of bed rest. Am J Physiol Regul Integr Comp Physiol 294:R939-R947
    • (2008) Am J Physiol Regul Integr Comp Physiol , vol.294
    • Trappe, S.1    Creer, A.2    Minchev, K.3    Slivka, D.4    Louis, E.5    Luden, N.6    Trappe, T.7
  • 79
    • 66149124537 scopus 로고    scopus 로고
    • Exercise in space: Human skeletal muscle after 6 months aboard the International Space Station
    • 19150852 10.1152/japplphysiol.91578.2008
    • Trappe S, Costill D, Gallagher P, Creer A, Peters JR, Evans H, Riley DA, Fitts RH (2009) Exercise in space: human skeletal muscle after 6 months aboard the International Space Station. J Appl Physiol 106:1159-1168
    • (2009) J Appl Physiol , vol.106 , pp. 1159-1168
    • Trappe, S.1    Costill, D.2    Gallagher, P.3    Creer, A.4    Peters, J.R.5    Evans, H.6    Riley, D.A.7    Fitts, R.H.8
  • 80
    • 0035746196 scopus 로고    scopus 로고
    • Fluid volume control during short-term space flight and implications for human performance
    • 11581336 1:STN:280:DC%2BD3MrjsVansw%3D%3D
    • Watenpaugh DE (2001) Fluid volume control during short-term space flight and implications for human performance. J Exp Biol 204:3209-3215
    • (2001) J Exp Biol , vol.204 , pp. 3209-3215
    • Watenpaugh, D.E.1
  • 82
    • 0000581478 scopus 로고    scopus 로고
    • The cardiovascular system in microgravity
    • Watenpaugh DE, Hargens AR (1996) The cardiovascular system in microgravity. Handbook of physiology, pp 631-674
    • (1996) Handbook of Physiology , pp. 631-674
    • De, W.1    Hargens, A.R.2
  • 83
    • 36849016786 scopus 로고    scopus 로고
    • Lower body negative pressure exercise plus brief postexercise lower body negative pressure improve post-bed rest orthostatic tolerance
    • 17947505 10.1152/japplphysiol.00132.2007
    • Watenpaugh DE, O'Leary DD, Schneider SM, Lee SM, Macias BR, Tanaka K, Hughson RL, Hargens AR (2007) Lower body negative pressure exercise plus brief postexercise lower body negative pressure improve post-bed rest orthostatic tolerance. J Appl Physiol 103:1964-1972
    • (2007) J Appl Physiol , vol.103 , pp. 1964-1972
    • Watenpaugh, D.E.1    O'Leary, D.D.2    Schneider, S.M.3    Lee, S.M.4    Macias, B.R.5    Tanaka, K.6    Hughson, R.L.7    Hargens, A.R.8
  • 84
    • 15744366644 scopus 로고    scopus 로고
    • Simulated microgravity enhances cerebral artery vasoconstriction and vascular resistance through endothelial nitric oxide mechanism
    • 15576439 10.1152/ajpheart.00925.2004 1:CAS:528:DC%2BD2MXjtlOrt7k%3D
    • Wilkerson MK, Lesniewski LA, Golding EM, Bryan RM Jr, Amin A, Wilson E, Delp MD (2005) Simulated microgravity enhances cerebral artery vasoconstriction and vascular resistance through endothelial nitric oxide mechanism. Am J Physiol Heart Circ Physiol 288:H1652-H1661
    • (2005) Am J Physiol Heart Circ Physiol , vol.288
    • Wilkerson, M.K.1    Lesniewski, L.A.2    Golding, E.M.3    Bryan, Jr.R.M.4    Amin, A.5    Wilson, E.6    Delp, M.D.7
  • 85
    • 84863259239 scopus 로고    scopus 로고
    • Peripheral arterial and venous response to tilt test after a 60-day bedrest with and without countermeasures (ES-IBREP)
    • 22412933 10.1371/journal.pone.0032854 1:CAS:528:DC%2BC38XktF2gtrc%3D
    • Yuan M, Coupe M, Bai Y, Gauquelin-Koch G, Jiang S, Aubry P, Wan Y, Custaud MA, Li Y, Arbeille P (2012) Peripheral arterial and venous response to tilt test after a 60-day bedrest with and without countermeasures (ES-IBREP). PLoS One 7:e32854
    • (2012) PLoS One , vol.7 , pp. 32854
    • Yuan, M.1    Coupe, M.2    Bai, Y.3    Gauquelin-Koch, G.4    Jiang, S.5    Aubry, P.6    Wan, Y.7    Custaud, M.A.8    Li, Y.9    Arbeille, P.10
  • 86
    • 4644223973 scopus 로고    scopus 로고
    • Vascular adaptation to microgravity
    • 15487032 10.1152/japplphysiol.00534.2003 author reply 1585-1587
    • Zhang LF (2004) Vascular adaptation to microgravity. J Appl Physiol 97:1584-1585 author reply 1585-1587
    • (2004) J Appl Physiol , vol.97 , pp. 1584-1585
    • Zhang, L.F.1
  • 87
    • 33845989095 scopus 로고    scopus 로고
    • Lower body negative pressure treadmill exercise as a countermeasure for bed rest-induced bone loss in female identical twins
    • 17070743 10.1016/j.bone.2006.09.014
    • Zwart SR, Hargens AR, Lee SM, Macias BR, Watenpaugh DE, Tse K, Smith SM (2007) Lower body negative pressure treadmill exercise as a countermeasure for bed rest-induced bone loss in female identical twins. Bone 40:529-537
    • (2007) Bone , vol.40 , pp. 529-537
    • Zwart, S.R.1    Hargens, A.R.2    Lee, S.M.3    Macias, B.R.4    Watenpaugh, D.E.5    Tse, K.6    Smith, S.M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.