Endothelium-dependent vasodilation of cerebral arteries is altered with simulated microgravity through nitric oxide synthase and EDHF mechanisms

Journal of Applied Physiology

Volumn 101, Issue 1, 2006, Pages 348-353

  Prisby, Rhonda D ^a   Wilkerson, M Keith ^b   Sokoya, Elke M ^c   Bryan Jr , Robert M ^c   Wilson, Emily ^d   Delp, Michael D ^a  

^a WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d TEXAS A M COLLEGE OF MEDICINE   (United States)

Author keywords

Cerebral blood flow; Endothelium dependent hyperpolarizing factor; Hindlimb unloading; Middle cerebral artery; Orthostatic intolerance

Indexed keywords

2 METHYLTHIOADENOSINE TRIPHOSPHATE; BRADYKININ; CAVEOLIN 1; INDOMETACIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE INHIBITOR; NITROPRUSSIDE SODIUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; BED REST; BRAIN ARTERY; BRAIN CIRCULATION; BRAIN PERFUSION; CONTROLLED STUDY; DOSE RESPONSE; DRUG INHIBITION; FLUID SHIFT; IMMUNOBLOTTING; IN VITRO STUDY; MALE; MICROGRAVITY; MIDDLE CEREBRAL ARTERY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; VASODILATATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; BIOLOGICAL FACTORS; BRADYKININ; CAVEOLIN 1; CEREBRAL ARTERIES; CYCLOOXYGENASE INHIBITORS; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HINDLIMB SUSPENSION; INDOMETHACIN; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE TYPE III; NITROPRUSSIDE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; THIONUCLEOTIDES; VASODILATION; VASODILATOR AGENTS; WEIGHTLESSNESS;

EID: 33745833959     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00941.2005     Document Type: Article

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