Exercise within lower body negative pressure partially counteracts lumbar spine deconditioning associated with 28-day bed rest

Journal of Applied Physiology

Volumn 99, Issue 1, 2005, Pages 39-44

  Cao, Peihong ^a   Kimura, Shinji ^b   Macias, Brandon R ^a   Ueno, Toshiaki ^a   Watenpaugh, Donald E ^c   Hargens, Alan R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^c SLEEP CONSULTANTS INC   (United States)

Author keywords

Countermeasures; Intervertebral disk height; Lumbar spine length; Simulated microgravity; Spinal curvature

Indexed keywords

ADULT; ARTICLE; BED REST; CLINICAL ARTICLE; CONTROLLED STUDY; EXERCISE; FEMALE; HUMAN; INTERVERTEBRAL DISK; LORDOSIS; LOWER BODY NEGATIVE PRESSURE; LUMBAR SPINE; MALE; MICROGRAVITY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SUPINE POSITION; TREADMILL EXERCISE;

NASA DISCIPLINE MUSCULOSKELETAL; NON-NASA CENTER;

ADAPTATION, PHYSIOLOGICAL; ADULT; BED REST; EXERCISE; EXERCISE THERAPY; FEMALE; HUMANS; LOWER BODY NEGATIVE PRESSURE; LUMBAR VERTEBRAE; MALE; SPINAL CURVATURES; TREATMENT OUTCOME; TWINS, MONOZYGOTIC; WEIGHT-BEARING; WEIGHTLESSNESS SIMULATION;

EID: 21644440039     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.01400.2004     Document Type: Article

References (32)

1. Adams MA and Hutton WC. The effect of posture on the fluid content of lumbar intervertebral discs. Spine 8: 665-671, 1983.
2. Andersson GB, Murphy RW, Ortengre R, and Nachemson AL. The influence of backrest inclination and lumbar support on lumbar lordosis. Spine 4: 52-58, 1979.
3. Boda WL, Watenpaugh DE, Ballard RE, and Hargens AR. Supine lower body negative pressure exercise simulates metabolic and kinetic features of upright exercise. J Appl Physiol 89: 649-654, 2000.
4. Brown JW. Crew height measurements. In: The Apollo-Soyuz Test Project: Medical Report. Washington, DC: NASA, 1977, p. 119-121. (Spec. NASA Rep. SP-411)
5. Convertino VA. Planning strategies for development of effective exercise and nutrition countermeasures for long-duration space flight. Nutrition 18: 880-888, 2002.
6. Dabbs VM and Dabbs LG. Correlation between disc height narrowing and low-back pain. Spine 15: 1366-1369, 1990.
7. Farfan HF, Huberdeau RM, and Dubow HI. Lumbar intervertebral disc degeneration. J Bone Joint Surg Am 54: 492-510, 1972.
8. Hargens AR, Hutchinson KJ, Ballard RE, and Murthy G. Intervertebral disc: loaded on Earth and unloaded in space. In: Connective Tissue Biology: Integration and Reductionism, edited by Reed R and Rubin K. London: Portland Press, 1998, p. 125-133.
9. Hargens AR, Whalen RT, Watenpaugh DE, Schwandt DF, and Krock LP. Lower body negative pressure to provide load bearing in space. Aviat Space Environ Med 62: 934-937, 1991.
10. Hutchinson KJ, Watenpaugh DE, Murthy G, Convertino VA, and Hargens AR. Back pain during 6 degrees head-down tilt approximates that during actual microgravity. Aviat Space Environ Med 66: 256-259, 1995.
11. Hutton WC, Malko JA, and Fajman WA. Lumbar disc volume measured by MRI: effects of bed rest, horizontal exercise, and vertical loading. Aviat Space Environ Med 74: 73-78, 2003.
12. Hutton WC, Yoon ST, Elmer WA, Li J, Murakami H, Minamide A, and Akamaru T. Effect of tail suspension (or simulated weightlessness) on the lumbar intervertebral disc: study of proteoglycans and collagen. Spine 27: 1286-1290, 2002.
13. Itoi E. Roentgenographic analysis of posture in spinal osteoporotics. Spine 16: 750-756, 1991.
14. Kimura S, Steinbach GC, Watenpauch DE, and Hargens AR. Lumbar spine disc height and curvature responses to an axial load generated by a compression device compatible with magnetic resonance imaging. Spine 26: 2596-2600, 2001.
15. LeBlanc A, Evans HJ, Schneider VS, Wendt RE 3rd, and Hedrick TD. Changes in intervertebral disc cross-sectional area with bed rest and space flight. Spine 19: 812-817, 1994.
16. LeBlanc A, Gogia P, Schneider V, Krebs J, Schonfeld E, and Evans H. Calf muscle area and strength changes after five weeks of horizontal bed rest. Am J Sports Med 16: 624-629, 1988.
17. LeBlanc A, Rowe R, Schneider V, Evans H, and Hedrick T. Regional muscle loss after short duration spaceflight. Aviat Space Environ Med 66: 1151-1154, 1995.
18. Lee SU, Hargens AR, Fredericson M, and Lang PK. Lumbar spine disc heights and curvature: upright posture vs. supine compression harness. Aviat Space Environ Med 74: 512-516, 2003.
19. Malko JA, Hutton WC, and Fajman WA. An in vivo magnetic resonance imaging study of changes in the volume (and fluid content) of the lumbar intervertebral discs during a simulated diurnal load cycle. Spine 24: 1015-1022, 1999.
20. McGill SM and Axler CT. Changes in spine height throughout 32 hours of bedrest. Arch Phys Med Rehabil 77: 1071-1073, 1996.
21. Murthy G, Watenpaugh DE, Ballard RE, and Hargens AR. Exercise against lower body negative pressure as a countermeasure for cardiovascular and musculoskeletal deconditioning. Acta Astronaut 33: 89-96, 1994.
22. Nachemson AL. Disc pressure measurements. Spine 6: 93-97, 1981.
23. Noshir A, Langrana W, Edwards T, and Sharma M. Biomechanical analysis of loads on the lumbar spine. In: The Lumbar Spine/The International Society for ihe Study of Lumbar Spine (2nd ed.), edited by Wiesel SW, Weinstein JN, Herkowitz H, DvoŘák J, and Bell G. Philadelphia, PA: Saunders, 1996, vol. 1, chapt. 4, p. 163-181.
24. Pavy Le-Traon A, Rous De Feneyrols A, Cornac A, Abdeseelam R, N'uygen D, Lazerges M, Guell A, and Bes A. Psychomotor performance during a 28 day head-down tilt with and without lower body negative pressure. Acta Astronaut 32: 319-330, 1994.
25. Sinha RK, Shah SA, Hume EL, and Tuan RS. The effect of a 5-day space flight on the immature rat spine. Spine 2: 239-243, 2002.
26. Smith SM, Davis-Street JE, Fesperman JV, Calkins DS, Bawa M, Macias BR, Meyer RS, and Hargens AR. Evaluation of treadmill exercise in a lower body negative pressure chamber as a countermeasure for weightlessness-induced bone loss: a bed rest study with identical twins. J Bone Miner Res 18: 2223-2230, 2003.
27. Styf JR, Ballard RE, Fechner K, Watenpaugh DE, Kahan NJ, and Hargens AR. Height increase, neuromuscular function, and back pain during 6 degree head-down tilt with traction. Aviat Space Environ Med 68: 24-29, 1997.
28. Thornton WE and Moore TP. Height changes in microgravity. In: Results of the Life Sciences DSOs Conducted Aboard the Space Shuttle 1981-1986, edited by Bungo MW, Bagian TM, Bowman MA, and Levitan BM. Houston, TX: NASA-Johnson Space Center, 1987, p. 55-57.
29. Thornton WE, Hoffler GW, and Rummel JA. Anthropometric changes and fluid shifts. In: Biomedical Results from Skylab. Houston, TX: NASA, 1977.
30. Urban JP and Maroudas A, Swelling of the intervertebral disc in vitro. Connect Tissue Res 9: 1-10, 1981.
31. Watenpaugh DE, Ballard RE, Schneider SM, Lee SM, Ertl AC, William JM, Boda WL, Hutchinson KJ, and Hargens AR. Supine lower body negative pressure exercise during bed rest maintains upright exercise capacity. J Appl Physiol 89: 218-227, 2000.
32. Wing PC, Tsang IK, Susak L, Gagnon F, Gagnon R, and Potts JE. Back pain and spinal changes in microgravity. Orthop Clin North Am 22: 255-262, 1991.