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Volumn 19, Issue 10, 2013, Pages 625-632

Is CD69 an effective brake to control inflammatory diseases?

Author keywords

CD69; Immunoregulation; Inflammatory diseases; Th17 lymphocytes; Treg lymphocytes

Indexed keywords

CD69 ANTIGEN;

EID: 84884815357     PISSN: 14714914     EISSN: 1471499X     Source Type: Journal    
DOI: 10.1016/j.molmed.2013.07.006     Document Type: Review
Times cited : (140)

References (77)
  • 1
    • 14644387445 scopus 로고    scopus 로고
    • CD69 is an immunoregulatory molecule induced following activation
    • Sancho D., et al. CD69 is an immunoregulatory molecule induced following activation. Trends Immunol. 2005, 26:136-140.
    • (2005) Trends Immunol. , vol.26 , pp. 136-140
    • Sancho, D.1
  • 2
    • 0024247067 scopus 로고
    • Triggering of T cell proliferation through AIM, an activation inducer molecule expressed on activated human lymphocytes
    • Cebrian M., et al. Triggering of T cell proliferation through AIM, an activation inducer molecule expressed on activated human lymphocytes. J. Exp. Med. 1988, 168:1621-1637.
    • (1988) J. Exp. Med. , vol.168 , pp. 1621-1637
    • Cebrian, M.1
  • 3
    • 0024390970 scopus 로고
    • T cell activation via Leu-23 (CD69)
    • Testi R., et al. T cell activation via Leu-23 (CD69). J. Immunol. 1989, 143:1123-1128.
    • (1989) J. Immunol. , vol.143 , pp. 1123-1128
    • Testi, R.1
  • 4
    • 78049398753 scopus 로고    scopus 로고
    • CD69 association with Jak3/Stat5 proteins regulates Th17 cell differentiation
    • Martin P., et al. CD69 association with Jak3/Stat5 proteins regulates Th17 cell differentiation. Mol. Cell. Biol. 2010, 30:4877-4889.
    • (2010) Mol. Cell. Biol. , vol.30 , pp. 4877-4889
    • Martin, P.1
  • 5
    • 84860818905 scopus 로고    scopus 로고
    • Type II membrane protein CD69 regulates the formation of resting T-helper memory
    • Shinoda K.E.A. Type II membrane protein CD69 regulates the formation of resting T-helper memory. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:7409-7414.
    • (2012) Proc. Natl. Acad. Sci. U.S.A. , vol.109 , pp. 7409-7414
    • Shinoda, K.E.A.1
  • 6
    • 84868157014 scopus 로고    scopus 로고
    • CD69 does not affect the extent of T cell priming
    • Alari-Pahissa E., et al. CD69 does not affect the extent of T cell priming. PLoS ONE 2012, 7:e48593.
    • (2012) PLoS ONE , vol.7
    • Alari-Pahissa, E.1
  • 7
    • 84862153245 scopus 로고    scopus 로고
    • + regulatory T cells following adoptive transfer
    • + regulatory T cells following adoptive transfer. Eur. J. Immunol. 2012, 42:1429-1435.
    • (2012) Eur. J. Immunol. , vol.42 , pp. 1429-1435
    • Lieberman, S.M.1
  • 8
    • 33645289121 scopus 로고    scopus 로고
    • CD69 acts downstream of interferon-α/β to inhibit S1P1 and lymphocyte egress from lymphoid organs
    • Shiow L.R., et al. CD69 acts downstream of interferon-α/β to inhibit S1P1 and lymphocyte egress from lymphoid organs. Nature 2006, 440:540-544.
    • (2006) Nature , vol.440 , pp. 540-544
    • Shiow, L.R.1
  • 9
    • 79958846495 scopus 로고    scopus 로고
    • CD69 modulates sphingosine-1-phosphate-induced migration of skin dendritic cells
    • Lamana A., et al. CD69 modulates sphingosine-1-phosphate-induced migration of skin dendritic cells. J. Invest. Dermatol. 2011, 131:1503-1512.
    • (2011) J. Invest. Dermatol. , vol.131 , pp. 1503-1512
    • Lamana, A.1
  • 10
    • 0142217899 scopus 로고    scopus 로고
    • CD69 downregulates autoimmune reactivity through active transforming growth factor-β production in collagen-induced arthritis
    • Sancho D., et al. CD69 downregulates autoimmune reactivity through active transforming growth factor-β production in collagen-induced arthritis. J. Clin. Invest. 2003, 112:872-882.
    • (2003) J. Clin. Invest. , vol.112 , pp. 872-882
    • Sancho, D.1
  • 11
    • 77955920583 scopus 로고    scopus 로고
    • The leukocyte activation antigen CD69 limits allergic asthma and skin contact hypersensitivity
    • Martin P., et al. The leukocyte activation antigen CD69 limits allergic asthma and skin contact hypersensitivity. J. Allergy Clin. Immunol. 2010, 126:355-365.
    • (2010) J. Allergy Clin. Immunol. , vol.126 , pp. 355-365
    • Martin, P.1
  • 12
    • 77958470132 scopus 로고    scopus 로고
    • CD69 limits the severity of cardiomyopathy after autoimmune myocarditis
    • Cruz-Adalia A., et al. CD69 limits the severity of cardiomyopathy after autoimmune myocarditis. Circulation 2010, 122:1396-1404.
    • (2010) Circulation , vol.122 , pp. 1396-1404
    • Cruz-Adalia, A.1
  • 13
    • 84856837493 scopus 로고    scopus 로고
    • CD69 regulates type I IFN-induced tolerogenic signals to mucosal CD4 T cells that attenuate their colitogenic potential
    • Radulovic K., et al. CD69 regulates type I IFN-induced tolerogenic signals to mucosal CD4 T cells that attenuate their colitogenic potential. J. Immunol. 2012, 188:2001-2013.
    • (2012) J. Immunol. , vol.188 , pp. 2001-2013
    • Radulovic, K.1
  • 14
    • 57749192648 scopus 로고    scopus 로고
    • Atherosclerosis development in apolipoprotein E-null mice deficient for CD69
    • Gomez M., et al. Atherosclerosis development in apolipoprotein E-null mice deficient for CD69. Cardiovasc. Res. 2009, 81:197-205.
    • (2009) Cardiovasc. Res. , vol.81 , pp. 197-205
    • Gomez, M.1
  • 15
    • 33644856279 scopus 로고    scopus 로고
    • The proatherogenic role of T cells requires cell division and is dependent on the stage of the disease
    • Khallou-Laschet J., et al. The proatherogenic role of T cells requires cell division and is dependent on the stage of the disease. Arterioscler. Thromb. Vasc. Biol. 2006, 26:353-358.
    • (2006) Arterioscler. Thromb. Vasc. Biol. , vol.26 , pp. 353-358
    • Khallou-Laschet, J.1
  • 16
    • 12444265792 scopus 로고    scopus 로고
    • CD69-null mice protected from arthritis induced with anti-type II collagen antibodies
    • Murata K., et al. CD69-null mice protected from arthritis induced with anti-type II collagen antibodies. Int. Immunol. 2003, 15:987-992.
    • (2003) Int. Immunol. , vol.15 , pp. 987-992
    • Murata, K.1
  • 17
    • 76249132174 scopus 로고    scopus 로고
    • CD69 controls the pathogenesis of allergic airway inflammation
    • Miki-Hosokawa T., et al. CD69 controls the pathogenesis of allergic airway inflammation. J. Immunol. 2009, 183:8203-8215.
    • (2009) J. Immunol. , vol.183 , pp. 8203-8215
    • Miki-Hosokawa, T.1
  • 18
    • 80053475925 scopus 로고    scopus 로고
    • Attenuation of lung inflammation and fibrosis in CD69-deficient mice after intratracheal bleomycin
    • Yamauchi K., et al. Attenuation of lung inflammation and fibrosis in CD69-deficient mice after intratracheal bleomycin. Respir. Res. 2011, 12:131.
    • (2011) Respir. Res. , vol.12 , pp. 131
    • Yamauchi, K.1
  • 19
    • 80955143781 scopus 로고    scopus 로고
    • Cigarette smoke-induced pulmonary inflammation is attenuated in CD69-deficient mice
    • Tsuyusaki J., et al. Cigarette smoke-induced pulmonary inflammation is attenuated in CD69-deficient mice. J. Recept. Signal. Transduct. Res. 2011, 31:434-439.
    • (2011) J. Recept. Signal. Transduct. Res. , vol.31 , pp. 434-439
    • Tsuyusaki, J.1
  • 20
    • 33750231874 scopus 로고    scopus 로고
    • The role of CD69 in acute neutrophil-mediated inflammation
    • Lamana A., et al. The role of CD69 in acute neutrophil-mediated inflammation. Eur. J. Immunol. 2006, 36:2632-2638.
    • (2006) Eur. J. Immunol. , vol.36 , pp. 2632-2638
    • Lamana, A.1
  • 21
    • 0025834169 scopus 로고
    • Upregulated expression and function of VLA-4 fibronectin receptors on human activated T cells in rheumatoid arthritis
    • Laffon A., et al. Upregulated expression and function of VLA-4 fibronectin receptors on human activated T cells in rheumatoid arthritis. J. Clin. Invest. 1991, 88:546-552.
    • (1991) J. Clin. Invest. , vol.88 , pp. 546-552
    • Laffon, A.1
  • 22
    • 0025240631 scopus 로고
    • + T lymphocytes in viral chronic active hepatitis
    • + T lymphocytes in viral chronic active hepatitis. Gastroenterology 1990, 98:1029-1035.
    • (1990) Gastroenterology , vol.98 , pp. 1029-1035
    • Garcia-Monzon, C.1
  • 23
    • 0027323671 scopus 로고
    • Expression of CD69 antigen on synovial fluid T cells in patients with rheumatoid arthritis and other chronic synovitis
    • Afeltra A., et al. Expression of CD69 antigen on synovial fluid T cells in patients with rheumatoid arthritis and other chronic synovitis. Ann. Rheum. Dis. 1993, 52:457-460.
    • (1993) Ann. Rheum. Dis. , vol.52 , pp. 457-460
    • Afeltra, A.1
  • 24
    • 0030671044 scopus 로고    scopus 로고
    • Coexpression of CD69 and HLADR activation markers on synovial fluid T lymphocytes of patients affected by rheumatoid arthritis: a three-colour cytometric analysis
    • Afeltra A., et al. Coexpression of CD69 and HLADR activation markers on synovial fluid T lymphocytes of patients affected by rheumatoid arthritis: a three-colour cytometric analysis. Int. J. Exp. Pathol. 1997, 78:331-336.
    • (1997) Int. J. Exp. Pathol. , vol.78 , pp. 331-336
    • Afeltra, A.1
  • 25
    • 34547832867 scopus 로고    scopus 로고
    • Interleukin-15 and interferon-γ participate in the cross-talk between natural killer and monocytic cells required for tumour necrosis factor production
    • Gonzalez-Alvaro I., et al. Interleukin-15 and interferon-γ participate in the cross-talk between natural killer and monocytic cells required for tumour necrosis factor production. Arthritis Res. Ther. 2006, 8:R88.
    • (2006) Arthritis Res. Ther. , vol.8
    • Gonzalez-Alvaro, I.1
  • 26
    • 43449128415 scopus 로고    scopus 로고
    • Early lymphocyte activation in the synovial microenvironment in patients with osteoarthritis: comparison with rheumatoid arthritis patients and healthy controls
    • Rollin R., et al. Early lymphocyte activation in the synovial microenvironment in patients with osteoarthritis: comparison with rheumatoid arthritis patients and healthy controls. Rheumatol. Int. 2008, 28:757-764.
    • (2008) Rheumatol. Int. , vol.28 , pp. 757-764
    • Rollin, R.1
  • 27
    • 23444457756 scopus 로고    scopus 로고
    • Early T cell activation in the skin from patients with systemic sclerosis
    • Kalogerou A., et al. Early T cell activation in the skin from patients with systemic sclerosis. Ann. Rheum. Dis. 2005, 64:1233-1235.
    • (2005) Ann. Rheum. Dis. , vol.64 , pp. 1233-1235
    • Kalogerou, A.1
  • 28
    • 67650114978 scopus 로고    scopus 로고
    • The pronounced Th17 profile in systemic sclerosis (SSc) together with intracellular expression of TGFβ and IFNγ distinguishes SSc phenotypes
    • Radstake T.R., et al. The pronounced Th17 profile in systemic sclerosis (SSc) together with intracellular expression of TGFβ and IFNγ distinguishes SSc phenotypes. PLoS ONE 2009, 4:e5903.
    • (2009) PLoS ONE , vol.4
    • Radstake, T.R.1
  • 29
    • 76649142440 scopus 로고    scopus 로고
    • Transforming growth factor-β in systemic sclerosis (scleroderma)
    • Varga J., Whitfield M.L. Transforming growth factor-β in systemic sclerosis (scleroderma). Front. Biosci. (Schol. Ed.) 2009, 1:226-235.
    • (2009) Front. Biosci. (Schol. Ed.) , vol.1 , pp. 226-235
    • Varga, J.1    Whitfield, M.L.2
  • 30
    • 79958070141 scopus 로고    scopus 로고
    • Phenotype and function of natural killer cells in systemic lupus erythematosus: excess interferon-γ production in patients with active disease
    • Hervier B., et al. Phenotype and function of natural killer cells in systemic lupus erythematosus: excess interferon-γ production in patients with active disease. Arthritis Rheum. 2011, 63:1698-1706.
    • (2011) Arthritis Rheum. , vol.63 , pp. 1698-1706
    • Hervier, B.1
  • 31
    • 27244440325 scopus 로고    scopus 로고
    • Increased expression and release of functional tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by T cells from lupus patients with active disease
    • Rus V., et al. Increased expression and release of functional tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by T cells from lupus patients with active disease. Clin. Immunol. 2005, 117:48-56.
    • (2005) Clin. Immunol. , vol.117 , pp. 48-56
    • Rus, V.1
  • 32
    • 0035863868 scopus 로고    scopus 로고
    • Anti-CD69 autoantibodies cross-react with low density lipoprotein receptor-related protein 2 in systemic autoimmune diseases
    • Yu X., et al. Anti-CD69 autoantibodies cross-react with low density lipoprotein receptor-related protein 2 in systemic autoimmune diseases. J. Immunol. 2001, 166:1360-1369.
    • (2001) J. Immunol. , vol.166 , pp. 1360-1369
    • Yu, X.1
  • 33
    • 0042622563 scopus 로고    scopus 로고
    • Autoantibodies to low-density-lipoprotein-receptor-related protein 2 (LRP2) in systemic autoimmune diseases
    • Ooka S., et al. Autoantibodies to low-density-lipoprotein-receptor-related protein 2 (LRP2) in systemic autoimmune diseases. Arthritis Res. Ther. 2003, 5:R174-R180.
    • (2003) Arthritis Res. Ther. , vol.5
    • Ooka, S.1
  • 34
    • 0027514226 scopus 로고
    • + in patients with multiple sclerosis
    • + in patients with multiple sclerosis. Eur. Neurol. 1993, 33:152-155.
    • (1993) Eur. Neurol. , vol.33 , pp. 152-155
    • Perrella, O.1
  • 35
    • 4644335691 scopus 로고    scopus 로고
    • Cross-sectional and longitudinal analysis of myelin-reactive T cells in patients with multiple sclerosis
    • Lunemann J.D., et al. Cross-sectional and longitudinal analysis of myelin-reactive T cells in patients with multiple sclerosis. J. Neurol. 2004, 251:1111-1120.
    • (2004) J. Neurol. , vol.251 , pp. 1111-1120
    • Lunemann, J.D.1
  • 36
    • 80051864035 scopus 로고    scopus 로고
    • Increased T-cell immunity against aquaporin-4 and proteolipid protein in neuromyelitis optica
    • Matsuya N., et al. Increased T-cell immunity against aquaporin-4 and proteolipid protein in neuromyelitis optica. Int. Immunol. 2011, 23:565-573.
    • (2011) Int. Immunol. , vol.23 , pp. 565-573
    • Matsuya, N.1
  • 37
    • 42249101897 scopus 로고    scopus 로고
    • The Peyer's patch is a critical immunoregulatory site for mucosal tolerance in experimental autoimmune encephalomylelitis (EAE)
    • Song F., et al. The Peyer's patch is a critical immunoregulatory site for mucosal tolerance in experimental autoimmune encephalomylelitis (EAE). J. Autoimmun. 2008, 30:230-237.
    • (2008) J. Autoimmun. , vol.30 , pp. 230-237
    • Song, F.1
  • 38
    • 72649089874 scopus 로고    scopus 로고
    • Phenotypical and functional characterization of T helper 17 cells in multiple sclerosis
    • Brucklacher-Waldert V., et al. Phenotypical and functional characterization of T helper 17 cells in multiple sclerosis. Brain 2009, 132:3329-3341.
    • (2009) Brain , vol.132 , pp. 3329-3341
    • Brucklacher-Waldert, V.1
  • 39
    • 0345019905 scopus 로고    scopus 로고
    • Elevated CD69 expression on naive peripheral blood T-cells in hyperthyroid Graves' disease and autoimmune thyroiditis: discordant effect of methimazole on HLA-DR and CD69
    • Gessl A., Waldhausl W. Elevated CD69 expression on naive peripheral blood T-cells in hyperthyroid Graves' disease and autoimmune thyroiditis: discordant effect of methimazole on HLA-DR and CD69. Clin. Immunol. Immunopathol. 1998, 87:168-175.
    • (1998) Clin. Immunol. Immunopathol. , vol.87 , pp. 168-175
    • Gessl, A.1    Waldhausl, W.2
  • 40
    • 0028108180 scopus 로고
    • Adhesion molecules from the LFA-1/ICAM-1,3 and VLA-4/VCAM-1 pathways on T lymphocytes and vascular endothelium in Graves' and Hashimoto's thyroid glands
    • Marazuela M., et al. Adhesion molecules from the LFA-1/ICAM-1,3 and VLA-4/VCAM-1 pathways on T lymphocytes and vascular endothelium in Graves' and Hashimoto's thyroid glands. Eur. J. Immunol. 1994, 24:2483-2490.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2483-2490
    • Marazuela, M.1
  • 41
    • 33748741386 scopus 로고    scopus 로고
    • Regulatory T cells in human autoimmune thyroid disease
    • Marazuela M., et al. Regulatory T cells in human autoimmune thyroid disease. J. Clin. Endocrinol. Metab. 2006, 91:3639-3646.
    • (2006) J. Clin. Endocrinol. Metab. , vol.91 , pp. 3639-3646
    • Marazuela, M.1
  • 42
    • 47249092218 scopus 로고    scopus 로고
    • Skewed distribution of Th17 lymphocytes in patients with Wegener's granulomatosis in remission
    • Abdulahad W.H., et al. Skewed distribution of Th17 lymphocytes in patients with Wegener's granulomatosis in remission. Arthritis Rheum. 2008, 58:2196-2205.
    • (2008) Arthritis Rheum. , vol.58 , pp. 2196-2205
    • Abdulahad, W.H.1
  • 43
    • 0033060994 scopus 로고    scopus 로고
    • Phenotypic analysis of lymphocytes and monocytes/macrophages in peripheral blood and bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis
    • Wahlstrom J., et al. Phenotypic analysis of lymphocytes and monocytes/macrophages in peripheral blood and bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis. Thorax 1999, 54:339-346.
    • (1999) Thorax , vol.54 , pp. 339-346
    • Wahlstrom, J.1
  • 44
    • 77950670526 scopus 로고    scopus 로고
    • +CD28(null) cells?
    • +CD28(null) cells?. Clin. Exp. Immunol. 2010, 160:256-265.
    • (2010) Clin. Exp. Immunol. , vol.160 , pp. 256-265
    • Heron, M.1
  • 45
    • 33646056128 scopus 로고    scopus 로고
    • + T-cell activation is correlated with FEV1 in smokers
    • + T-cell activation is correlated with FEV1 in smokers. Respir. Med. 2006, 100:1088-1093.
    • (2006) Respir. Med. , vol.100 , pp. 1088-1093
    • Glader, P.1
  • 46
    • 0034074750 scopus 로고    scopus 로고
    • The expression of lymphocyte surface antigens in bronchial biopsies, bronchoalveolar lavage cells and blood cells in healthy smoking and never-smoking men, 60 years old
    • Ekberg-Jansson A., et al. The expression of lymphocyte surface antigens in bronchial biopsies, bronchoalveolar lavage cells and blood cells in healthy smoking and never-smoking men, 60 years old. Respir. Med. 2000, 94:264-272.
    • (2000) Respir. Med. , vol.94 , pp. 264-272
    • Ekberg-Jansson, A.1
  • 47
    • 0038065618 scopus 로고    scopus 로고
    • Increased expression of T cell activation markers (CD25, CD26, CD40L and CD69) in atherectomy specimens of patients with unstable angina and acute myocardial infarction
    • Hosono M., et al. Increased expression of T cell activation markers (CD25, CD26, CD40L and CD69) in atherectomy specimens of patients with unstable angina and acute myocardial infarction. Atherosclerosis 2003, 168:73-80.
    • (2003) Atherosclerosis , vol.168 , pp. 73-80
    • Hosono, M.1
  • 48
    • 59849119691 scopus 로고    scopus 로고
    • - T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-β1
    • - T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-β1. J. Immunol. 2009, 182:111-120.
    • (2009) J. Immunol. , vol.182 , pp. 111-120
    • Han, Y.1
  • 49
    • 0037016422 scopus 로고    scopus 로고
    • Changes in monocyte/macrophage neurotoxicity in the era of HAART: implications for HIV-associated dementia
    • Kusdra L., et al. Changes in monocyte/macrophage neurotoxicity in the era of HAART: implications for HIV-associated dementia. AIDS 2002, 16:31-38.
    • (2002) AIDS , vol.16 , pp. 31-38
    • Kusdra, L.1
  • 50
    • 0036860276 scopus 로고    scopus 로고
    • Evaluation of peripheral blood CD4 and CD8 lymphocyte subsets, CD69 expression and histologic rejection grade as diagnostic markers for the presence of cardiac allograft rejection
    • Creemers P., et al. Evaluation of peripheral blood CD4 and CD8 lymphocyte subsets, CD69 expression and histologic rejection grade as diagnostic markers for the presence of cardiac allograft rejection. Transpl. Immunol. 2002, 10:285-292.
    • (2002) Transpl. Immunol. , vol.10 , pp. 285-292
    • Creemers, P.1
  • 51
    • 0038299441 scopus 로고    scopus 로고
    • CD69 expression on peripheral CD8 T cells correlates with acute rejection in renal transplant recipients
    • Posselt A.M., et al. CD69 expression on peripheral CD8 T cells correlates with acute rejection in renal transplant recipients. Transplantation 2003, 76:190-195.
    • (2003) Transplantation , vol.76 , pp. 190-195
    • Posselt, A.M.1
  • 52
    • 79956288367 scopus 로고    scopus 로고
    • Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells
    • Sagoo P., et al. Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells. Sci. Transl. Med. 2011, 3:83ra42.
    • (2011) Sci. Transl. Med. , vol.3
    • Sagoo, P.1
  • 53
    • 9244245747 scopus 로고    scopus 로고
    • Kidney transplant patients with long-term graft survival have altered expression of molecules associated with T-cell activation
    • Alvarez C.M., et al. Kidney transplant patients with long-term graft survival have altered expression of molecules associated with T-cell activation. Transplantation 2004, 78:1541-1547.
    • (2004) Transplantation , vol.78 , pp. 1541-1547
    • Alvarez, C.M.1
  • 54
    • 0027507513 scopus 로고
    • CD69 is expressed by human eosinophils activated in vivo in asthma and in vitro by cytokines
    • Hartnell A., et al. CD69 is expressed by human eosinophils activated in vivo in asthma and in vitro by cytokines. Immunology 1993, 80:281-286.
    • (1993) Immunology , vol.80 , pp. 281-286
    • Hartnell, A.1
  • 55
    • 0032806755 scopus 로고    scopus 로고
    • CD69 surface expression on human lung eosinophils after segmental allergen provocation
    • Julius P., et al. CD69 surface expression on human lung eosinophils after segmental allergen provocation. Eur. Respir. J. 1999, 13:1253-1259.
    • (1999) Eur. Respir. J. , vol.13 , pp. 1253-1259
    • Julius, P.1
  • 56
    • 20044369571 scopus 로고    scopus 로고
    • Expansion of activated eosinophils in infants with severe atopic dermatitis
    • Toma T., et al. Expansion of activated eosinophils in infants with severe atopic dermatitis. Pediatr. Int. 2005, 47:32-38.
    • (2005) Pediatr. Int. , vol.47 , pp. 32-38
    • Toma, T.1
  • 57
    • 71349084630 scopus 로고    scopus 로고
    • T cells in sputum of asthmatic patients are activated independently of disease severity or control
    • Lourenco O., et al. T cells in sputum of asthmatic patients are activated independently of disease severity or control. Allergol. Immunopathol. (Madr.) 2009, 37:285-292.
    • (2009) Allergol. Immunopathol. (Madr.) , vol.37 , pp. 285-292
    • Lourenco, O.1
  • 58
    • 0030968756 scopus 로고    scopus 로고
    • Rapid expression of the CD69 antigen on T cells and natural killer cells upon antigenic stimulation of peripheral blood mononuclear cell suspensions
    • Werfel T., et al. Rapid expression of the CD69 antigen on T cells and natural killer cells upon antigenic stimulation of peripheral blood mononuclear cell suspensions. Allergy 1997, 52:465-469.
    • (1997) Allergy , vol.52 , pp. 465-469
    • Werfel, T.1
  • 59
    • 76249120530 scopus 로고    scopus 로고
    • Allergen provocation increases TH2-cytokines and FOXP3 expression in the asthmatic lung
    • Thunberg S., et al. Allergen provocation increases TH2-cytokines and FOXP3 expression in the asthmatic lung. Allergy 2010, 65:311-318.
    • (2010) Allergy , vol.65 , pp. 311-318
    • Thunberg, S.1
  • 60
    • 77953116038 scopus 로고    scopus 로고
    • Cutting edge: human latency-associated peptide + T cells: a novel regulatory T cell subset
    • Gandhi R., et al. Cutting edge: human latency-associated peptide + T cells: a novel regulatory T cell subset. J. Immunol. 2010, 184:4620-4624.
    • (2010) J. Immunol. , vol.184 , pp. 4620-4624
    • Gandhi, R.1
  • 61
    • 45849145442 scopus 로고    scopus 로고
    • Quantitative and qualitative deficiencies of regulatory T cells in patients with systemic lupus erythematosus (SLE)
    • Bonelli M., et al. Quantitative and qualitative deficiencies of regulatory T cells in patients with systemic lupus erythematosus (SLE). Int. Immunol. 2008, 20:861-868.
    • (2008) Int. Immunol. , vol.20 , pp. 861-868
    • Bonelli, M.1
  • 62
    • 33749520621 scopus 로고    scopus 로고
    • Regulatory T cells in patients with systemic lupus erythematosus
    • Alvarado-Sanchez B., et al. Regulatory T cells in patients with systemic lupus erythematosus. J. Autoimmun. 2006, 27:110-118.
    • (2006) J. Autoimmun. , vol.27 , pp. 110-118
    • Alvarado-Sanchez, B.1
  • 63
    • 80053128959 scopus 로고    scopus 로고
    • - T cells in patients with hepatocellular carcinoma are associated with tumor progression
    • - T cells in patients with hepatocellular carcinoma are associated with tumor progression. J. Gastroenterol. Hepatol. 2011, 26:1519-1526.
    • (2011) J. Gastroenterol. Hepatol. , vol.26 , pp. 1519-1526
    • Zhu, J.1
  • 64
    • 70349091377 scopus 로고    scopus 로고
    • Regulatory T cells in children with intestinal parasite infection
    • Garcia-Hernandez M.H., et al. Regulatory T cells in children with intestinal parasite infection. Parasite Immunol. 2009, 31:597-603.
    • (2009) Parasite Immunol. , vol.31 , pp. 597-603
    • Garcia-Hernandez, M.H.1
  • 65
    • 77958599125 scopus 로고    scopus 로고
    • CD69 limits early inflammatory diseases associated with immune response to Listeria monocytogenes infection
    • Vega-Ramos J., et al. CD69 limits early inflammatory diseases associated with immune response to Listeria monocytogenes infection. Immunol. Cell Biol. 2010, 88:707-715.
    • (2010) Immunol. Cell Biol. , vol.88 , pp. 707-715
    • Vega-Ramos, J.1
  • 66
    • 0032145230 scopus 로고    scopus 로고
    • + T cells expressing early activation antigen CD69 in murine lupus: possible abnormal regulatory role for cytokine imbalance
    • + T cells expressing early activation antigen CD69 in murine lupus: possible abnormal regulatory role for cytokine imbalance. J. Immunol. 1998, 161:1267-1273.
    • (1998) J. Immunol. , vol.161 , pp. 1267-1273
    • Ishikawa, S.1
  • 67
    • 77955896776 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells resident in human thymus drive natural Treg cell development
    • Martin-Gayo E., et al. Plasmacytoid dendritic cells resident in human thymus drive natural Treg cell development. Blood 2010, 115:5366-5375.
    • (2010) Blood , vol.115 , pp. 5366-5375
    • Martin-Gayo, E.1
  • 68
    • 84861546167 scopus 로고    scopus 로고
    • Mesenchymal stem cells promote the sustained expression of CD69 on activated T lymphocytes: roles of canonical and non-canonical NF-κB signalling
    • Saldanha-Araujo F., et al. Mesenchymal stem cells promote the sustained expression of CD69 on activated T lymphocytes: roles of canonical and non-canonical NF-κB signalling. J. Cell. Mol. Med. 2012, 16:1232-1244.
    • (2012) J. Cell. Mol. Med. , vol.16 , pp. 1232-1244
    • Saldanha-Araujo, F.1
  • 69
    • 79958000981 scopus 로고    scopus 로고
    • Regulatory T cells phenotype in different clinical forms of Chagas' disease
    • de Araujo F.F., et al. Regulatory T cells phenotype in different clinical forms of Chagas' disease. PLoS Negl. Trop. Dis. 2011, 5:e992.
    • (2011) PLoS Negl. Trop. Dis. , vol.5
    • de Araujo, F.F.1
  • 70
    • 67650128154 scopus 로고    scopus 로고
    • Increased frequency and compromised function of T regulatory cells in systemic sclerosis (SSc) is related to a diminished CD69 and TGFβ expression
    • Radstake T.R., et al. Increased frequency and compromised function of T regulatory cells in systemic sclerosis (SSc) is related to a diminished CD69 and TGFβ expression. PLoS ONE 2009, 4:e5981.
    • (2009) PLoS ONE , vol.4
    • Radstake, T.R.1
  • 71
    • 49649089269 scopus 로고    scopus 로고
    • Investigation of CD69 as a new candidate gene for rheumatoid arthritis
    • Rueda B., et al. Investigation of CD69 as a new candidate gene for rheumatoid arthritis. Tissue Antigens 2008, 72:206-210.
    • (2008) Tissue Antigens , vol.72 , pp. 206-210
    • Rueda, B.1
  • 72
    • 0015310519 scopus 로고
    • Suppressor T cells
    • Gershon R.K., et al. Suppressor T cells. J. Immunol. 1972, 108:586-590.
    • (1972) J. Immunol. , vol.108 , pp. 586-590
    • Gershon, R.K.1
  • 73
    • 0027436739 scopus 로고
    • Saying the 'S' word in public
    • Green D.R., Webb D.R. Saying the 'S' word in public. Immunol. Today 1993, 14:523-525.
    • (1993) Immunol. Today , vol.14 , pp. 523-525
    • Green, D.R.1    Webb, D.R.2
  • 74
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S., et al. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 1995, 155:1151-1164.
    • (1995) J. Immunol. , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1
  • 75
    • 79952814810 scopus 로고    scopus 로고
    • + regulatory T cells: their knowns and unknowns
    • + regulatory T cells: their knowns and unknowns. Immunol. Cell Biol. 2011, 89:346-351.
    • (2011) Immunol. Cell Biol. , vol.89 , pp. 346-351
    • Miyara, M.1    Sakaguchi, S.2
  • 76
    • 79954511312 scopus 로고    scopus 로고
    • Oral tolerance
    • Weiner H.L., et al. Oral tolerance. Immunol. Rev. 2011, 241:241-259.
    • (2011) Immunol. Rev. , vol.241 , pp. 241-259
    • Weiner, H.L.1
  • 77
    • 78449296907 scopus 로고    scopus 로고
    • IL-35-mediated induction of a potent regulatory T cell population
    • Collison L.W., et al. IL-35-mediated induction of a potent regulatory T cell population. Nat. Immunol. 2010, 11:1093-1101.
    • (2010) Nat. Immunol. , vol.11 , pp. 1093-1101
    • Collison, L.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.