메뉴 건너뛰기




Volumn 65, Issue 3, 2010, Pages 311-318

Allergen provocation increases TH2-cytokines and FOXP3 expression in the asthmatic lung

Author keywords

Allergy; Asthma; Bronchoalveolar lavage; FOXP3; Treg

Indexed keywords

CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 9; NEUTRALIZING ANTIBODY; POLLEN ANTIGEN; TRANSCRIPTION FACTOR FOXP3;

EID: 76249120530     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/j.1398-9995.2009.02218.x     Document Type: Article
Times cited : (55)

References (36)
  • 1
    • 0036051993 scopus 로고    scopus 로고
    • Emerging immune targets for the therapy of allergic asthma
    • Corry DB. Emerging immune targets for the therapy of allergic asthma. Nat Rev Drug Discov 2002 1 : 55 64.
    • (2002) Nat Rev Drug Discov , vol.1 , pp. 55-64
    • Corry, D.B.1
  • 2
    • 41449107295 scopus 로고    scopus 로고
    • Therapeutic approaches for control of transcription factors in allergic disease
    • Cousins DJ, McDonald J, Lee TH. Therapeutic approaches for control of transcription factors in allergic disease. J Allergy Clin Immunol 2008 121 : 803 809.
    • (2008) J Allergy Clin Immunol , vol.121 , pp. 803-809
    • Cousins, D.J.1    McDonald, J.2    Lee, T.H.3
  • 3
    • 33847415066 scopus 로고    scopus 로고
    • Natural regulatory T cells: Mechanisms of suppression
    • Miyara M, Sakaguchi S. Natural regulatory T cells: mechanisms of suppression. Trends Mol Med 2007 13 : 108 116.
    • (2007) Trends Mol Med , vol.13 , pp. 108-116
    • Miyara, M.1    Sakaguchi, S.2
  • 4
    • 11144354531 scopus 로고    scopus 로고
    • Th2 cells are less susceptible than Th1 cells to the suppressive activity of CD25 + regulatory thymocytes because of their responsiveness to different cytokines
    • Cosmi L, Liotta F, Angeli R, Mazzinghi B, Santarlasci V, Manetti R et al. Th2 cells are less susceptible than Th1 cells to the suppressive activity of CD25 + regulatory thymocytes because of their responsiveness to different cytokines. Blood 2004 103 : 3117 3121.
    • (2004) Blood , vol.103 , pp. 3117-3121
    • Cosmi, L.1    Liotta, F.2    Angeli, R.3    Mazzinghi, B.4    Santarlasci, V.5    Manetti, R.6
  • 5
    • 38549166301 scopus 로고    scopus 로고
    • GATA3-driven Th2 responses inhibit TGF-beta1-induced FOXP3 expression and the formation of regulatory T cells
    • Mantel PY, Kuipers H, Boyman O, Rhyner C, Ouaked N, Ruckert B et al. GATA3-driven Th2 responses inhibit TGF-beta1-induced FOXP3 expression and the formation of regulatory T cells. PLoS Biol 2007 5 : e329.
    • (2007) PLoS Biol , vol.5 , pp. 329
    • Mantel, P.Y.1    Kuipers, H.2    Boyman, O.3    Rhyner, C.4    Ouaked, N.5    Ruckert, B.6
  • 6
    • 34447509505 scopus 로고    scopus 로고
    • Immune regulation by CD4+ CD25+ T cells and interleukin-10 in birch pollen-allergic patients and non-allergic controls
    • Thunberg S, Akdis M, Akdis CA, Gronneberg R, Malmstrom V, Trollmo C et al. Immune regulation by CD4+ CD25+ T cells and interleukin-10 in birch pollen-allergic patients and non-allergic controls. Clin Exp Allergy 2007 37 : 1127 1136.
    • (2007) Clin Exp Allergy , vol.37 , pp. 1127-1136
    • Thunberg, S.1    Akdis, M.2    Akdis, C.A.3    Gronneberg, R.4    Malmstrom, V.5    Trollmo, C.6
  • 7
    • 1342308180 scopus 로고    scopus 로고
    • Relation of CD4+ CD25+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic disease
    • Ling EM, Smith T, Nguyen XD, Pridgeon C, Dallman M, Arbery J et al. Relation of CD4+ CD25+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic disease. Lancet 2004 363 : 608 615.
    • (2004) Lancet , vol.363 , pp. 608-615
    • Ling, E.M.1    Smith, T.2    Nguyen, X.D.3    Pridgeon, C.4    Dallman, M.5    Arbery, J.6
  • 8
    • 4544256262 scopus 로고    scopus 로고
    • Defective suppression of Th2 cytokines by CD4CD25 regulatory T cells in birch allergics during birch pollen season
    • Grindebacke H, Wing K, Andersson AC, Suri-Payer E, Rak S, Rudin A. Defective suppression of Th2 cytokines by CD4CD25 regulatory T cells in birch allergics during birch pollen season. Clin Exp Allergy 2004 34 : 1364 1372.
    • (2004) Clin Exp Allergy , vol.34 , pp. 1364-1372
    • Grindebacke, H.1    Wing, K.2    Andersson, A.C.3    Suri-Payer, E.4    Rak, S.5    Rudin, A.6
  • 9
    • 34247526094 scopus 로고    scopus 로고
    • Quantitative and functional impairment of pulmonary CD4+ CD25hi regulatory T cells in pediatric asthma
    • Hartl D, Koller B, Mehlhorn AT, Reinhardt D, Nicolai T, Schendel DJ et al. Quantitative and functional impairment of pulmonary CD4+ CD25hi regulatory T cells in pediatric asthma. J Allergy Clin Immunol 2007 119 : 1258 1266.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 1258-1266
    • Hartl, D.1    Koller, B.2    Mehlhorn, A.T.3    Reinhardt, D.4    Nicolai, T.5    Schendel, D.J.6
  • 10
    • 0028327560 scopus 로고
    • The leukotriene-antagonist ICI-204,219 inhibits the early airway reaction to cumulative bronchial challenge with allergen in atopic asthmatics
    • Dahlen B, Zetterstrom O, Bjorck T, Dahlen SE. The leukotriene-antagonist ICI-204,219 inhibits the early airway reaction to cumulative bronchial challenge with allergen in atopic asthmatics. Eur Respir J 1994 7 : 324 331.
    • (1994) Eur Respir J , vol.7 , pp. 324-331
    • Dahlen, B.1    Zetterstrom, O.2    Bjorck, T.3    Dahlen, S.E.4
  • 11
    • 0022447708 scopus 로고
    • Relationship between changed alveolar-capillary permeability and angiotensin converting enzyme activity in serum in sarcoidosis
    • Eklund A, Blaschke E. Relationship between changed alveolar-capillary permeability and angiotensin converting enzyme activity in serum in sarcoidosis. Thorax 1986 41 : 629 634.
    • (1986) Thorax , vol.41 , pp. 629-634
    • Eklund, A.1    Blaschke, E.2
  • 12
    • 42449125706 scopus 로고    scopus 로고
    • Low levels of endotoxin enhance allergen-stimulated proliferation and reduce the threshold for activation in human peripheral blood cells
    • Velickovic TC, Thunberg S, Polovic N, Neimert-Andersson T, Gronlund H, van Hage M et al. Low levels of endotoxin enhance allergen-stimulated proliferation and reduce the threshold for activation in human peripheral blood cells. Int Arch Allergy Immunol 2008 146 : 1 10.
    • (2008) Int Arch Allergy Immunol , vol.146 , pp. 1-10
    • Velickovic, T.C.1    Thunberg, S.2    Polovic, N.3    Neimert-Andersson, T.4    Gronlund, H.5    Van Hage, M.6
  • 15
    • 24644496854 scopus 로고    scopus 로고
    • IL-4-expressing bronchoalveolar T cells from asthmatic and healthy subjects preferentially express CCR 3 and CCR 4
    • Morgan AJ, Symon FA, Berry MA, Pavord ID, Corrigan CJ, Wardlaw AJ. IL-4-expressing bronchoalveolar T cells from asthmatic and healthy subjects preferentially express CCR 3 and CCR 4. J Allergy Clin Immunol 2005 116 : 594 600.
    • (2005) J Allergy Clin Immunol , vol.116 , pp. 594-600
    • Morgan, A.J.1    Symon, F.A.2    Berry, M.A.3    Pavord, I.D.4    Corrigan, C.J.5    Wardlaw, A.J.6
  • 17
    • 34047261246 scopus 로고    scopus 로고
    • Invariant natural killer T cells in asthma and chronic obstructive pulmonary disease
    • Vijayanand P, Seumois G, Pickard C, Powell RM, Angco G, Sammut D et al. Invariant natural killer T cells in asthma and chronic obstructive pulmonary disease. N Engl J Med 2007 356 : 1410 1422.
    • (2007) N Engl J Med , vol.356 , pp. 1410-1422
    • Vijayanand, P.1    Seumois, G.2    Pickard, C.3    Powell, R.M.4    Angco, G.5    Sammut, D.6
  • 19
    • 20844432429 scopus 로고    scopus 로고
    • Analysis of FOXP3 protein expression in human CD4+ CD25+ regulatory T cells at the single-cell level
    • Roncador G, Brown PJ, Maestre L, Hue S, Martinez-Torrecuadrada JL, Ling KL et al. Analysis of FOXP3 protein expression in human CD4+ CD25+ regulatory T cells at the single-cell level. Eur J Immunol 2005 35 : 1681 1691.
    • (2005) Eur J Immunol , vol.35 , pp. 1681-1691
    • Roncador, G.1    Brown, P.J.2    Maestre, L.3    Hue, S.4    Martinez-Torrecuadrada, J.L.5    Ling, K.L.6
  • 20
    • 34047174849 scopus 로고    scopus 로고
    • Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production
    • Allan SE, Crome SQ, Crellin NK, Passerini L, Steiner TS, Bacchetta R et al. Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production. Int Immunol 2007 19 : 345 354.
    • (2007) Int Immunol , vol.19 , pp. 345-354
    • Allan, S.E.1    Crome, S.Q.2    Crellin, N.K.3    Passerini, L.4    Steiner, T.S.5    Bacchetta, R.6
  • 21
    • 35448930435 scopus 로고    scopus 로고
    • Induction of FOXP3 expression in naive human CD4 + FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype
    • Tran DQ, Ramsey H, Shevach EM. Induction of FOXP3 expression in naive human CD4 + FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype. Blood 2007 110 : 2983 2990.
    • (2007) Blood , vol.110 , pp. 2983-2990
    • Tran, D.Q.1    Ramsey, H.2    Shevach, E.M.3
  • 22
    • 33947121146 scopus 로고    scopus 로고
    • Transient regulatory T-cells: A state attained by all activated human T-cells
    • Pillai V, Ortega SB, Wang CK, Karandikar NJ. Transient regulatory T-cells: a state attained by all activated human T-cells. Clin Immunol 2007 123 : 18 29.
    • (2007) Clin Immunol , vol.123 , pp. 18-29
    • Pillai, V.1    Ortega, S.B.2    Wang, C.K.3    Karandikar, N.J.4
  • 23
    • 33745817085 scopus 로고    scopus 로고
    • CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
    • Liu W, Putnam AL, Xu-Yu Z, Szot GL, Lee MR, Zhu S et al. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med 2006 203 : 1701 1711.
    • (2006) J Exp Med , vol.203 , pp. 1701-1711
    • Liu, W.1    Putnam, A.L.2    Xu-Yu, Z.3    Szot, G.L.4    Lee, M.R.5    Zhu, S.6
  • 24
    • 33745813929 scopus 로고    scopus 로고
    • Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
    • Seddiki N, Santner-Nanan B, Martinson J, Zaunders J, Sasson S, Landay A et al. Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J Exp Med 2006 203 : 1693 1700.
    • (2006) J Exp Med , vol.203 , pp. 1693-1700
    • Seddiki, N.1    Santner-Nanan, B.2    Martinson, J.3    Zaunders, J.4    Sasson, S.5    Landay, A.6
  • 25
    • 33847624061 scopus 로고    scopus 로고
    • The levels of CD4+CD25+ regulatory T cells in paediatric patients with allergic rhinitis and bronchial asthma
    • Lee JH, Yu HH, Wang LC, Yang YH, Lin YT, Chiang BL. The levels of CD4+CD25+ regulatory T cells in paediatric patients with allergic rhinitis and bronchial asthma. Clin Exp Immunol 2007 148 : 53 63.
    • (2007) Clin Exp Immunol , vol.148 , pp. 53-63
    • Lee, J.H.1    Yu, H.H.2    Wang, L.C.3    Yang, Y.H.4    Lin, Y.T.5    Chiang, B.L.6
  • 26
    • 0028873098 scopus 로고
    • Nonallergic individuals recognize the same T cell epitopes of Bet v 1, the major birch pollen allergen, as atopic patients
    • Ebner C, Schenk S, Najafian N, Siemann U, Steiner R, Fischer GW et al. Nonallergic individuals recognize the same T cell epitopes of Bet v 1, the major birch pollen allergen, as atopic patients. J Immunol 1995 154 : 1932 1940.
    • (1995) J Immunol , vol.154 , pp. 1932-1940
    • Ebner, C.1    Schenk, S.2    Najafian, N.3    Siemann, U.4    Steiner, R.5    Fischer, G.W.6
  • 27
    • 3042665666 scopus 로고    scopus 로고
    • Allergen-specific T cells from birch-pollen-allergic patients and healthy controls differ in T helper 2 cytokine and in interleukin-10 production
    • Bullens DM, Van Den Keybus C, Dilissen E, Kasran A, Ceuppens JL. Allergen-specific T cells from birch-pollen-allergic patients and healthy controls differ in T helper 2 cytokine and in interleukin-10 production. Clin Exp Allergy 2004 34 : 879 887.
    • (2004) Clin Exp Allergy , vol.34 , pp. 879-887
    • Bullens, D.M.1    Van Den Keybus, C.2    Dilissen, E.3    Kasran, A.4    Ceuppens, J.L.5
  • 28
    • 44449145067 scopus 로고    scopus 로고
    • Assessment of Bet v 1-specific CD4+ T cell responses in allergic and nonallergic individuals using MHC class II peptide tetramers
    • Van Overtvelt L, Wambre E, Maillere B, von Hofe E, Louise A, Balazuc AM et al. Assessment of Bet v 1-specific CD4+ T cell responses in allergic and nonallergic individuals using MHC class II peptide tetramers. J Immunol 2008 180 : 4514 4522.
    • (2008) J Immunol , vol.180 , pp. 4514-4522
    • Van Overtvelt, L.1    Wambre, E.2    Maillere, B.3    Von Hofe, E.4    Louise, A.5    Balazuc, A.M.6
  • 29
    • 2942709797 scopus 로고    scopus 로고
    • Differential regulatory capacity of CD25+ T regulatory cells and preactivated CD25+ T regulatory cells on development, functional activation, and proliferation of Th2 cells
    • Stassen M, Jonuleit H, Muller C, Klein M, Richter C, Bopp T et al. Differential regulatory capacity of CD25+ T regulatory cells and preactivated CD25+ T regulatory cells on development, functional activation, and proliferation of Th2 cells. J Immunol 2004 173 : 267 274.
    • (2004) J Immunol , vol.173 , pp. 267-274
    • Stassen, M.1    Jonuleit, H.2    Muller, C.3    Klein, M.4    Richter, C.5    Bopp, T.6
  • 30
    • 36649003890 scopus 로고    scopus 로고
    • The functional insufficiency of human CD4 + CD25 high T-regulatory cells in allergic asthma is subjected to TNF-alpha modulation
    • Lin YL, Shieh CC, Wang JY. The functional insufficiency of human CD4 + CD25 high T-regulatory cells in allergic asthma is subjected to TNF-alpha modulation. Allergy 2008 63 : 67 74.
    • (2008) Allergy , vol.63 , pp. 67-74
    • Lin, Y.L.1    Shieh, C.C.2    Wang, J.Y.3
  • 31
    • 47249153897 scopus 로고    scopus 로고
    • Up-regulation and activation of eosinophil integrins in blood and airway after segmental lung antigen challenge
    • Johansson MW, Kelly EA, Busse WW, Jarjour NN, Mosher DF. Up-regulation and activation of eosinophil integrins in blood and airway after segmental lung antigen challenge. J Immunol 2008 180 : 7622 7635.
    • (2008) J Immunol , vol.180 , pp. 7622-7635
    • Johansson, M.W.1    Kelly, E.A.2    Busse, W.W.3    Jarjour, N.N.4    Mosher, D.F.5
  • 32
    • 0032979945 scopus 로고    scopus 로고
    • Interleukin 5 release into asthmatic airways 4 and 24 hours after endobronchial allergen challenge: Its relationship with eosinophil recruitment
    • Teran LM, Carroll MP, Shute JK, Holgate ST. Interleukin 5 release into asthmatic airways 4 and 24 hours after endobronchial allergen challenge: its relationship with eosinophil recruitment. Cytokine 1999 11 : 518 522.
    • (1999) Cytokine , vol.11 , pp. 518-522
    • Teran, L.M.1    Carroll, M.P.2    Shute, J.K.3    Holgate, S.T.4
  • 33
    • 56349154943 scopus 로고    scopus 로고
    • Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset
    • Veldhoen M, Uyttenhove C, van Snick J, Helmby H, Westendorf A, Buer J et al. Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nat Immunol 2008 9 : 1341 1346.
    • (2008) Nat Immunol , vol.9 , pp. 1341-1346
    • Veldhoen, M.1    Uyttenhove, C.2    Van Snick, J.3    Helmby, H.4    Westendorf, A.5    Buer, J.6
  • 34
    • 56349093347 scopus 로고    scopus 로고
    • IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells
    • Dardalhon V, Awasthi A, Kwon H, Galileos G, Gao W, Sobel RA et al. IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells. Nat Immunol 2008 9 : 1347 1355.
    • (2008) Nat Immunol , vol.9 , pp. 1347-1355
    • Dardalhon, V.1    Awasthi, A.2    Kwon, H.3    Galileos, G.4    Gao, W.5    Sobel, R.A.6
  • 36
    • 0038518063 scopus 로고    scopus 로고
    • Segmental allergen challenge in patients with atopic asthma leads to increased IL-9 expression in bronchoalveolar lavage fluid lymphocytes
    • Erpenbeck VJ, Hohlfeld JM, Volkmann B, Hagenberg A, Geldmacher H, Braun A et al. Segmental allergen challenge in patients with atopic asthma leads to increased IL-9 expression in bronchoalveolar lavage fluid lymphocytes. J Allergy Clin Immunol 2003 111 : 1319 1327.
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 1319-1327
    • Erpenbeck, V.J.1    Hohlfeld, J.M.2    Volkmann, B.3    Hagenberg, A.4    Geldmacher, H.5    Braun, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.