CD69 Does Not Affect the Extent of T Cell Priming

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Alari Pahissa, Elisenda ^a,b   Notario, Laura ^a   Lorente, Elena ^a   Vega Ramos, Javier ^c   Justel, Ana ^d   López, Daniel ^a   Villadangos, José A ^c   Lauzurica, Pilar ^a  

^a INSTITUTO DE SALUD CARLOS III   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD69; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN DETECTION; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ANTIGEN SPECIFICITY; ARTICLE; CD8+ T LYMPHOCYTE; CELL MATURATION; CONTROLLED STUDY; DENDRITIC CELL; FLOW CYTOMETRY; GENE INACTIVATION; GENE TARGETING; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; LYMPH NODE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MOUSE; NONHUMAN; T CELL PRIMING; T LYMPHOCYTE; TRANSGENIC MOUSE; VACCINIA;

ADOPTIVE TRANSFER; ANIMALS; ANTIGEN PRESENTATION; ANTIGENS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CELLS, CULTURED; DENDRITIC CELLS; FEMALE; FLOW CYTOMETRY; LECTINS, C-TYPE; LIPOPOLYSACCHARIDES; LYMPH NODES; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; OLIGODEOXYRIBONUCLEOTIDES; T-LYMPHOCYTES; UP-REGULATION; VACCINIA; VACCINIA VIRUS;

MUS; VACCINIA VIRUS;

EID: 84868157014     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0048593     Document Type: Article

References (46)

1. Ziegler SF, Ramsdell F, Alderson MR, (1994) The activation antigen CD69. Stem Cells 12: 456-465.
2. Ziegler SF, Levin SD, Johnson L, Copeland NG, Gilbert DJ, et al. (1994) The mouse CD69 gene. Structure, expression, and mapping to the NK gene complex. J Immunol 152: 1228-1236.
3. Feng H, Zhang D, Palliser D, Zhu P, Cai S, et al. (2005) Listeria-infected myeloid dendritic cells produce IFN-beta, priming T cell activation. J Immunol 175: 421-432.
4. Testi R, Phillips JH, Lanier LL, (1989) T cell activation via Leu-23 (CD69). J Immunol 143: 1123-1128.
5. Rasmussen AM, Blomhoff HK, Stokke T, Horejsi V, Smeland EB, (1994) Cross-linking of CD53 promotes activation of resting human B lymphocytes. J Immunol 153: 4997-5007.
6. Henrickson SE, von Andrian UH, (2007) Single-cell dynamics of T-cell priming. Curr Opin Immunol 19: 249-258.
7. Hodge G, Hodge S, Han P, Haslam R, (2004) Multiple leucocyte activation markers to detect neonatal infection. Clin Exp Immunol 135: 125-129.
8. Bohler T, Walcher J, Holzl-Wenig G, Schnitzler P, Geiss M, et al. (1999) Expression of CD69 on T-cells from HIV-1-infected children and adolescents increases with increasing viral load. Eur J Pediatr 158: 638-644.
9. Iwashiro M, Messer RJ, Peterson KE, Stromnes IM, Sugie T, et al. (2001) Immunosuppression by CD4+ regulatory T cells induced by chronic retroviral infection. Proc Natl Acad Sci U S A 98: 9226-9230.
10. Vega-Ramos J, Alari-Pahissa E, Valle JD, Carrasco-Marin E, Esplugues E, et al. (2010) CD69 limits early inflammatory diseases associated with immune response to Listeria monocytogenes infection. Immunol Cell Biol 88: 707-715.
11. Iannone F, Corrigal VM, Panayi GS, (1996) CD69 on synovial T cells in rheumatoid arthritis correlates with disease activity. Br J Rheumatol 35: 397.
12. Atzeni F, Del Papa N, Sarzi-Puttini P, Bertolazzi F, Minonzio F, et al. (2004) CD69 expression on neutrophils from patients with rheumatoid arthritis. Clin Exp Rheumatol 22: 331-334.
13. Laffon A, Garcia-Vicuna R, Humbria A, Postigo AA, Corbi AL, et al. (1991) Upregulated expression and function of VLA-4 fibronectin receptors on human activated T cells in rheumatoid arthritis. J Clin Invest 88: 546-552.
14. Ortiz AM, Laffon A, Gonzalez-Alvaro I, (2002) CD69 expression on lymphocytes and interleukin-15 levels in synovial fluids from different inflammatory arthropathies. Rheumatol Int 21: 182-188.
15. Portales-Perez D, Gonzalez-Amaro R, Abud-Mendoza C, Sanchez-Armass S, (1997) Abnormalities in CD69 expression, cytosolic pH and Ca2+ during activation of lymphocytes from patients with systemic lupus erythematosus. Lupus 6: 48-56.
16. Ishikawa S, Akakura S, Abe M, Terashima K, Chijiiwa K, et al. (1998) A subset of CD4+ T cells expressing early activation antigen CD69 in murine lupus: possible abnormal regulatory role for cytokine imbalance. J Immunol 161: 1267-1273.
17. Van den Hove LE, Van Gool SW, Van Poppel H, Baert L, Coorevits L, et al. (1997) Phenotype, cytokine production and cytolytic capacity of fresh (uncultured) tumour-infiltrating T lymphocytes in human renal cell carcinoma. Clin Exp Immunol 109: 501-509.
18. Epardaud M, Elpek KG, Rubinstein MP, Yonekura AR, Bellemare-Pelletier A, et al. (2008) Interleukin-15/interleukin-15R alpha complexes promote destruction of established tumors by reviving tumor-resident CD8+ T cells. Cancer Res 68: 2972-2983.
19. Groh V, Rhinehart R, Randolph-Habecker J, Topp MS, Riddell SR, et al. (2001) Costimulation of CD8alphabeta T cells by NKG2D via engagement by MIC induced on virus-infected cells. Nat Immunol 2: 255-260.
20. Tian W, Nunez R, Cheng S, Ding Y, Tumang J, et al. (2005) C-type lectin OCILRP2/Clr-g and its ligand NKRP1f costimulate T cell proliferation and IL-2 production. Cell Immunol 234: 39-53.
21. Figdor CG, van Kooyk Y, Adema GJ, (2002) C-type lectin receptors on dendritic cells and Langerhans cells. Nat Rev Immunol 2: 77-84.
22. van Vliet SJ, Garcia-Vallejo JJ, van Kooyk Y, (2008) Dendritic cells and C-type lectin receptors: coupling innate to adaptive immune responses. Immunol Cell Biol 86: 580-587.
23. Nakamura S, Sung SS, Bjorndahl JM, Fu SM, (1989) Human T cell activation. IV. T cell activation and proliferation via the early activation antigen EA 1. J Exp Med 169: 677-689.
24. Risso A, Cosulich ME, Rubartelli A, Mazza MR, Bargellesi A, (1989) MLR3 molecule is an activation antigen shared by human B, T lymphocytes and T cell precursors. Eur J Immunol 19: 323-328.
25. Santis AG, Campanero MR, Alonso JL, Tugores A, Alonso MA, et al. (1992) Tumor necrosis factor-alpha production induced in T lymphocytes through the AIM/CD69 activation pathway. Eur J Immunol 22: 1253-1259.
26. Cebrian M, Yague E, Rincon M, Lopez-Botet M, de Landazuri MO, et al. (1988) Triggering of T cell proliferation through AIM, an activation inducer molecule expressed on activated human lymphocytes. J Exp Med 168: 1621-1637.
27. Lauzurica P, Sancho D, Torres M, Albella B, Marazuela M, et al. (2000) Phenotypic and functional characteristics of hematopoietic cell lineages in CD69-deficient mice. Blood 95: 2312-2320.
28. Esplugues E, Sancho D, Vega-Ramos J, Martinez C, Syrbe U, et al. (2003) Enhanced antitumor immunity in mice deficient in CD69. J Exp Med 197: 1093-1106.
29. Sancho D, Gomez M, Viedma F, Esplugues E, Gordon-Alonso M, et al. (2003) CD69 downregulates autoimmune reactivity through active transforming growth factor-beta production in collagen-induced arthritis. J Clin Invest 112: 872-882.
30. Martin P, Gomez M, Lamana A, Matesanz Marin AM, Cortes JR, et al. (2010) The leukocyte activation antigen CD69 limits allergic asthma and skin contact hypersensitivity. J Allergy Clin Immunol 126: 355-365, 365 e351-353.
31. Cruz-Adalia A, Jimenez-Borreguero LJ, Ramirez-Huesca M, Chico-Calero I, Barreiro O, et al. (2010) CD69 limits the severity of cardiomyopathy after autoimmune myocarditis. Circulation 122: 1396-1404.
32. Esplugues E, Vega-Ramos J, Cartoixa D, Vazquez BN, Salaet I, et al. (2005) Induction of tumor NK-cell immunity by anti-CD69 antibody therapy. Blood 105: 4399-4406.
33. Sancho D, Gomez M, Martinez Del Hoyo G, Lamana A, Esplugues E, et al. (2006) CD69 targeting differentially affects the course of collagen-induced arthritis. J Leukoc Biol 80: 1233-1241.
34. Alari-Pahissa E, Vega-Ramos J, Zhang JG, Castano AR, Turley SJ, et al. (2012) Differential effect of CD69 targeting on bystander and antigen-specific T cell proliferation. J Leukoc Biol 92: 145-158.
35. Firat H, Garcia-Pons F, Tourdot S, Pascolo S, Scardino A, et al. (1999) H-2 class I knockout, HLA-A2.1-transgenic mice: a versatile animal model for preclinical evaluation of antitumor immunotherapeutic strategies. Eur J Immunol 29: 3112-3121.
36. Vremec D, Shortman K, (2008) The isolation and identification of murine dendritic cell populations from lymphoid tissues and their production in culture. Methods Mol Biol 415: 163-178.
37. Lorente E, Infantes S, Barnea E, Beer I, Garcia R, et al. (2012) Multiple viral ligands naturally presented by different class I molecules in transporter antigen processing-deficient vaccinia virus-infected cells. J Virol 86: 527-541.
38. Restifo NP, Bacik I, Irvine KR, Yewdell JW, McCabe BJ, et al. (1995) Antigen processing in vivo and the elicitation of primary CTL responses. J Immunol 154: 4414-4422.
39. Lorente E, Garcia R, Mir C, Barriga A, Lemonnier FA, et al. (2012) Role of metalloproteases in vaccinia virus epitope processing for transporter associated with antigen processing (TAP)-independent human leukocyte antigen (HLA)-B7 class I antigen presentation. J Biol Chem 287: 9990-10000.
40. Young LJ, Wilson NS, Schnorrer P, Proietto A, ten Broeke T, et al. (2008) Differential MHC class II synthesis and ubiquitination confers distinct antigen-presenting properties on conventional and plasmacytoid dendritic cells. Nat Immunol 9: 1244-1252.
41. Vremec D, O'Keeffe M, Wilson A, Ferrero I, Koch U, et al. (2010) Factors determining the spontaneous activation of splenic dendritic cells in culture. Innate Immun.
42. Bachmann MF, McKall-Faienza K, Schmits R, Bouchard D, Beach J, et al. (1997) Distinct roles for LFA-1 and CD28 during activation of naive T cells: adhesion versus costimulation. Immunity 7: 549-557.
43. Hara T, Jung LK, Bjorndahl JM, Fu SM, (1986) Human T cell activation. III. Rapid induction of a phosphorylated 28 kD/32 kD disulfide-linked early activation antigen (EA 1) by 12-o-tetradecanoyl phorbol-13-acetate, mitogens, and antigens. J Exp Med 164: 1988-2005.
44. Cosulich ME, Rubartelli A, Risso A, Cozzolino F, Bargellesi A, (1987) Functional characterization of an antigen involved in an early step of T-cell activation. Proc Natl Acad Sci U S A 84: 4205-4209.
45. Carrero JA, Calderon B, Unanue ER, (2006) Lymphocytes are detrimental during the early innate immune response against Listeria monocytogenes. J Exp Med 203: 933-940.
46. Martin P, Gomez M, Lamana A, Cruz-Adalia A, Ramirez-Huesca M, et al. (2010) CD69 association with Jak3/Stat5 proteins regulates Th17 cell differentiation. Mol Cell Biol 30: 4877-4889.