Manipulating the antigen-specific immune response by the hydrophobicity of amphiphilic poly(γ-glutamic acid) nanoparticles

Biomaterials

Volumn 34, Issue 37, 2013, Pages 9709-9716

  Shima, Fumiaki ^a,b   Akagi, Takami ^a,b   Uto, Tomofumi ^a,b   Akashi, Mitsuru ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Adjuvant; Hydrophobicity; Immunoengineering; Nanoparticles; Vaccine

Indexed keywords

ACTIVATION POTENTIAL; ADJUVANT; DENDRITIC CELLS (DCS); IMMUNE RESPONSE; IMMUNOENGINEERING; NANOPARTICLE (NPS); VACCINE ADJUVANTS; VACCINE CARRIERS;

AMINO ACIDS; ANTIGENS; GRAFTING (CHEMICAL); HYDROPHOBICITY; NANOPARTICLES; VACCINES;

IMMUNE SYSTEM;

AMPHIPHILIC POLY( GAMMA GLUTAMIC ACID) NANOPARTICLE; FLUORESCEIN ISOTHIOCYANATE; INTERLEUKIN 12; INTERLEUKIN DERIVATIVE; NANOPARTICLE; OVALBUMIN; PHENYLALANINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VACCINE;

ADJUVANT THERAPY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; CELL ACTIVATION; CELL STIMULATION; CELLULAR IMMUNITY; CONTROLLED STUDY; DENDRITIC CELL; DRUG SAFETY; FEMALE; GENE EXPRESSION PROFILING; HYDROPHOBICITY; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; MOUSE; NANOENCAPSULATION; NONHUMAN; PRIORITY JOURNAL;

ADJUVANT; HYDROPHOBICITY; IMMUNOENGINEERING; NANOPARTICLES; VACCINE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGENS; CELLS, CULTURED; DENDRITIC CELLS; FEMALE; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; IMMUNITY, CELLULAR; MICE; MICE, INBRED C57BL; NANOPARTICLES; OVALBUMIN; PHENYLALANINE; POLYGLUTAMIC ACID;

EID: 84884815126     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.08.064     Document Type: Article

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