Intracellular degradation and distribution of protein-encapsulated amphiphilic poly(amino acid) nanoparticles

Biomaterials

Volumn 32, Issue 21, 2011, Pages 4959-4967

  Akagi, Takami ^a,b   Shima, Fumiaki ^a   Akashi, Mitsuru ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Intracellular degradation; Macrophages; Nanoparticles; Particle size; Vaccine

Indexed keywords

AMPHIPHILICS; BIODEGRADABLE NANOPARTICLE; CELLULAR UPTAKE; DEGRADATION KINETICS; ENCAPSULATED NANOPARTICLES; ENCAPSULATED PROTEINS; ENDOSOMES; GLUTAMIC ACID; IMMUNE RESPONSE; IN-VIVO; INTRACELLULAR DEGRADATION; INTRACELLULAR DISTRIBUTION; OVALBUMINS; PHYSICOCHEMICAL PROPERTY; POLY(AMINO ACID)S; POLYMERIC NANOPARTICLES; RATIONAL DESIGN; SIZE EFFECTS; VACCINE DELIVERY SYSTEM;

AMINO ACIDS; ANTIGENS; CYTOLOGY; DEGRADATION; MACROPHAGES; PARTICLE SIZE; PROTEINS; VACCINES;

NANOPARTICLES;

AMPHOPHILE; NANOPARTICLE; OVALBUMIN; POLYAMINOACID; POLYGLUTAMIC ACID; VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN SPECIFICITY; ARTICLE; BIODEGRADABILITY; CELL SHAPE; CELLULAR DISTRIBUTION; CHEMICAL COMPOSITION; CONTROLLED STUDY; CYTOPLASM; DEGRADATION; ENCAPSULATION; ENDOSOME; HYDROPHOBICITY; IMMUNE RESPONSE; IN VIVO STUDY; MACROPHAGE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SURFACE PROPERTY;

AMINO ACIDS; ANIMALS; BIOCOMPATIBLE MATERIALS; CELL LINE; FLUORESCEIN; MACROPHAGES; MATERIALS TESTING; MICE; NANOPARTICLES; OVALBUMIN; PARTICLE SIZE; SURFACE-ACTIVE AGENTS;

EID: 79955757739     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.03.049     Document Type: Article

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