Ablation of p2X7 receptor exacerbates gliosis and motoneuron death in the SOD1-G93A mouse model of amyotrophic lateral sclerosis

Human Molecular Genetics

Volumn 22, Issue 20, 2013, Pages 4102-4116

  Apolloni, Savina ^a,b   Amadio, Susanna ^b   Montilli, Cinzia ^b   Volonté, Cinzia ^a,b   D'ambrosi, Nadia ^a,b  

^a CNR   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE; PURINERGIC P2X7 RECEPTOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; BODY WEIGHT; CONTROLLED STUDY; DISEASE COURSE; DISEASE EXACERBATION; FEMALE; GLIOSIS; KNOCKOUT MOUSE; LIFESPAN; LUMBAR SPINAL CORD; MALE; MOTONEURON; MOUSE; MSOD1 MOUSE; NONHUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; ROTAROD TEST;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BODY WEIGHT; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FEMALE; GLIOSIS; INFLAMMATION; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASES; MOTOR ACTIVITY; MOTOR NEURONS; NADPH OXIDASE; NITRIC OXIDE SYNTHASE TYPE II; RECEPTORS, PURINERGIC P2X7; SPINAL CORD; SUPEROXIDE DISMUTASE; TIME FACTORS;

EID: 84884709663     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt259     Document Type: Article

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