Epigenetic regulation is a crucial factor in the repression of UGT1A1 expression in the human kidney

Drug Metabolism and Disposition

Volumn 41, Issue 10, 2013, Pages 1738-1743

  Oda, Shingo ^a   Fukami, Tatsuki ^a   Yokoi, Tsuyoshi ^a   Nakajima, Miki ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; DNA; GLUCURONOSYLTRANSFERASE 1A1; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HISTONE H3; MESSENGER RNA; TRICHOSTATIN A;

ARTICLE; CELL TYPE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; EPIGENETIC REPRESSION; GENETIC TRANSFECTION; HISTONE ACETYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; KIDNEY CELL; KIDNEY PARENCHYMA; LIVER CELL; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; TISSUE SPECIFICITY;

ACETYLATION; ADOLESCENT; ADULT; AGED, 80 AND OVER; CELL LINE; CELL LINE, TUMOR; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCURONOSYLTRANSFERASE; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; HISTONES; HUMANS; KIDNEY; LIVER; MALE; MIDDLE AGED; PROMOTER REGIONS, GENETIC;

EID: 84884685162     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.113.051201     Document Type: Article

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