The hedgehog Pathway Gene shifted Functions together with the hmgcr-Dependent Isoprenoid Biosynthetic Pathway to Orchestrate Germ Cell Migration

PLoS Genetics

Volumn 9, Issue 9, 2013, Pages

  Deshpande, Girish ^a   Zhou, Keren ^a   Wan, Joy Y ^a   Friedrich, Jana ^b   Jourjine, Nicholas ^a   Smith, Daniel ^a   Schedl, Paul ^a,c  

^a PRINCETON UNIVERSITY   (United States)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c INSTITUTE OF GENE BIOLOGY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

ISOPRENOID; PROTEOGLYCAN; SONIC HEDGEHOG PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BASOLATERAL MEMBRANE; BIOSYNTHESIS; CELL MIGRATION; CONTROLLED STUDY; EMBRYO; FEMALE; FORELIMB; GAIN OF FUNCTION MUTATION; GENE; GENE EXPRESSION; GENE FUNCTION; GENETIC DISTANCE; HH GENE; HMGCR GENE; LIGAND BINDING; LOSS OF FUNCTION MUTATION; MALE; MESODERM; NERVOUS SYSTEM; NONHUMAN; PRIMORDIAL GERM CELL; PROTEIN SECRETION; SHF GENE; SIGNAL TRANSDUCTION; SOMATIC GONADAL PRECURSOR CELL; STEM CELL;

ANIMALS; BLASTODERM; CELL MOVEMENT; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EMBRYO, NONMAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GERM CELLS; GONADS; GTP-BINDING PROTEIN GAMMA SUBUNITS; GTP-BINDING PROTEINS; HEDGEHOG PROTEINS; HIGH MOBILITY GROUP PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; PROTEIN BINDING; SIGNAL TRANSDUCTION; TERPENES; WING;

EID: 84884684581     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003720     Document Type: Article

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