Hedgehog signaling in germ cell migration

Cell

Volumn 106, Issue 6, 2001, Pages 759-769

  Deshpande, Girish ^a   Swanhart, Lisa ^a   Chiang, Phyllis ^a   Schedl, Paul ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SIGNAL RECOGNITION PARTICLE;

ANIMAL EXPERIMENT; ARTICLE; CELL CONTACT; CELL MIGRATION; CELL MOTION; CONTROLLED STUDY; DROSOPHILA; EMBRYO; FEMALE; GENE CONTROL; GENE EXPRESSION; GERM CELL; GERM LINE; MALE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SOMATIC CELL;

EID: 0035929145     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(01)00488-3     Document Type: Article

References (58)

1. Hedgehog and its patched-smoothened receptor complex: A novel signaling mechanism at the cell surface
2. The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal
3. Maternal pumilio acts together with Nanos in germline development in Drosophila embryos
4. Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor
5. Tinman and bagpipe: Two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila
6. Segmentation and specification of the Drosophila mesoderm
7. Specification, migration and assembly of the somatic cells of the Drosophila gonad
8. Expression and function of clift in the development of somatic gonadal precursors within the Drosophila mesoderm
9. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
10. zfh-1 is required for germ cell migration and gonadal mesoderm development in Drosophila
11. The 412 retrotransposon and the development of gonadal mesoderm in Drosophila
12. Dual roles for patched in sequestering and transducing Hedgehog
13. In vivo evidence that patched and smoothened constitute distinct binding and transducing components of a Hedgehog receptor complex
14. Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression
15. Use of a yeast site-specific recombinase to produce female germline chimeras in Drosophila
16. On the range of hedgehog signaling
17. Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened
18. Scute (sis-b) function in Drosophila sex determination
19. Novel functions of nanos in downregulating mitosis and transcription during the development of the Drosophila germline
20. Induction of germ cell formation by Oskar
21. Nanos and Pumilio have critical roles in the development and function of Drosophila germline stem cells
22. Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo
23. Drosophila hedgehog acts as a morphogen in cellular patterning
24. The Drosophila patched gene encodes a putative membrane protein required for segmental patterning
25. Attractive genetics
26. The active migration of Drosophila primordial germ cells
27. Transducing Hedgehog: The story so far
28. New players and puzzles in the Hedgehog signaling pathway
29. Transducing the Hedgehog signal
30. Essential role of the posterior morphogen nanos for germline development in Drosophila
31. A C. elegans patched gene, ptc-1, functions in germ-line cytokinesis
32. Localization and functions of protein kinase A during Drosophila oogenesis
33. Induction of identified mesodermal cells by CNS midline progenitors in Drosophila
34. An absolute requirement for Cubitus interruptus in Hedgehog signaling
35. Gonadal mesoderm and fat body initially follow a common developmental path in Drosophila
36. Identification of genes controlling germ cell migration and embryonic gonad formation in Drosophila
37. A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched
38. Hedgehog patterning activity: Role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain
39. Cholesterol modification of hedgehog signaling proteins in animal development
40. A putative serine/threonine protein kinase encoded by the segment-polarity fused gene of Drosophila
41. Hedgehog signal transduction in the posterior compartment of the Drosophila wing imaginal disc
42. The genetic control of the distinction between fat body and gonadal mesoderm in Drosophila
43. The serpent gene is necessary for progression through the early stages of fat-body development
44. Launching the germline in Caenorhabditis elegans: Regulation of gene expression in early germ cells
45. Overexpression of oskar directs ectopic activation of nanos and presumptive pole cell formation in Drosophila embryos
46. dpp induces mesodermal gene expression in Drosophila
47. Pole plasm and the posterior group genes
48. A Hedgehog activity gradient contributes to AP axial patterning of the Drosophila wing
49. Hedgehog acts by distinct gradient and signal relay mechanisms to organise cell type and cell polarity in the Drosophila abdomen
50. Effects of oncogenic mutations in smoothened and patched can be reversed by cyclopamine
51. Smoothened encodes a receptor-like serpentine protein required for hedgehog signalling
52. HMG-CoA reductase guides migrating primordial germ cells
53. Nuclear import of cubitus interruptus is regulated by hedgehog via a mechanism distinct from Ci stabilization and Ci activation
54. Primordial germ cell migration and the assembly of the Drosophila embryonic gonad
55. Germ cell development in Drosophila
56. Division and migration of nuclei during early embryogenesis of Drosophila melanogaster
57. Identification and genetic analysis of wunen, a gene guiding Drosophila melanogaster germ cell migration
58. The Drosophila protein Wunen repels migrating germ cells