Comparative anatomical distribution of serotonin 1A, 1Dα and 2A receptor mRNAs in human brain postmortem

Molecular Brain Research

Volumn 39, Issue 1-2, 1996, Pages 223-233

  Pasqualetti, Massimo ^a   Nardi, Irma ^a   Ladinsky, Herbert ^b   Marazziti, Donatella ^a   Cassano, Giovanni B ^a  

^a UNIVERSITY OF PISA   (Italy)

^b Boehringer Ingelheim Italia SpA   (Italy)

Author keywords

Gene expression; Human brain; Hybridization histochemistry; In situ; Serotonin; Serotonin receptors

Indexed keywords

BRAIN RECEPTOR; MESSENGER RNA; SEROTONIN 1A RECEPTOR; SEROTONIN 1D RECEPTOR; SEROTONIN 2A RECEPTOR;

ADULT; AGED; ARTICLE; AUTOPSY; BRAIN CORTEX; BRAIN REGION; CAUDATE NUCLEUS; DENTATE GYRUS; FEMALE; GRANULAR CELL; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; MALE; PRIORITY JOURNAL; PUTAMEN; PYRAMIDAL NERVE CELL; RECEPTOR DENSITY; RECEPTOR GENE; RNA PROBE; TISSUE DISTRIBUTION;

EID: 0029888565     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0169-328X(96)00026-5     Document Type: Article

References (44)

1. 1A receptors mediate opposing responses on membrane excitability in rat association cortex, Neuroscience, 40 (1991) 399-412.
2. 2A receptors in the rat medial prefrontal cortex: an iontophoretic study, Synapse, 17 (1994) 173-181.
3. 1A receptor mRNA in neurons of the human brainstem, Synapse, 18 (1994) 279-279.
4. 3H]5-HT, in frontal cortex and the hippocampal region of the human brain, Brain Res., 638 (1994) 85-94.
5. 1D receptor binding affinity of 5-hydroxytryptamine, 5-carboxytryptamine and sumatriptan in the central nervous system of seven species, Eur. J. Pharmacol., 213 (1992) 193-197.
6. Boess, F.G. and Martin, I.L., Molecular biology of 5-HT receptors, Neuropharmacology, 33 (1994) 275-317.
7. 1B receptor is localized predominantly on axon terminals, Neuroscience, 58 (1994) 167-172.
8. 1F receptor messenger RNA in rodent and primate brain, Neuropharmacology, 33 (1994) 376-386.
9. 2A receptor mRNA in human brain, Brain Res., 676 (1995) 157-168.
10. 1A binding in rat brain: a combined in situ hybridization/in vitro receptor autoradiographic study, Brain Res., 561 (1993) 51-60.
11. Cox, K.H., DeLeon, D.V., Angerer, L.M., and Angerer, R.C., Detection of mRNAs in sea urchin embryos by in situ hybridization using asymmetric RNA probes, Dev. Biol., 101 (1984) 485-502.
12. Deakin, J.F.W. and Pennel, I., 5-HTergic receptor subtypes in depression, Psychopharmacology, S24, 1989.
13. De Montigny, C., Chaput, Y., and Blier, P., Classical and novel targets for antidepressants. In: J. Mendlewicz, N. Brunello, and S.Z. Langer (Eds.), New Pharmacologycal Approach to the Treatment of Depressive Disorders, Karger Press, Basel, 1993, pp. 8-17.
14. 1A, Nature, 335 (1988) 358-360.
15. Gelders, Y.G., Thymosthenic agents, a novel approach in the treatment of schizophrenia, Br. J. Psychiatry, 155 (Suppl. 5) (1989) 33-36.
16. 4 receptor: molecular cloning and pharmacological characterization of two splice variants, EMBO J., 14 (1995) 2806-2815.
17. Gerlach, J., New antipsychotics: classification, efficacy, and adverse effects. Schiz. Bull., 155 (Suppl. 5) (1991) 33-36.
18. 2 agonist or antagonist?, Neuropsychopharmacology, 3 (1990) 509-517.
19. 1D-type serotonin receptor, Mol. Pharmacol., 40 (1991) 143-148.
20. Jacobs, B.L. and Formal, C.A., Serotonin and behaviour: a general hypothesis. In: F.E. Bloom, and H.Y. Meltzer (Eds.), Psychopharmacology: the Fourth Generation of Progress, Raven Press, New York, 1995, pp. 461-469.
21. Jacobs, B.L. and Azmitia, E.C., Structure and function of the brain serotonin system, Physiol. Rev., 72 (1992) 165-229.
22. Leysen, J.C., Gommeren, W., Eens, A., de Chaffoy de Courcelles, D., Stoof, J.C., Janssen, P.A.J., Biochemical profile of risperidone, a new antipsychotic, J. Pharmacol. Exp. Ther., 247 (1988) 661-670.
23. Lucki, I. and Wieland, S., 5-Hydroxytryptamine receptors and behavioral responses, Neuropsychopharmacology, 3 (1990) 481-493.
24. Martin, G.R. and Humphrey, P.P.A., Receptors for 5-hydroxytryptamine: current perspectives on classification and nomenclature, Neuropharmacology, 33 (1994) 261-273.
25. 1A receptor in rat hippocampus, Brain Res., 590 (1992) 229-238.
26. Murphy, D.L., Neuropsychiatric disorders and the multiple human brain 5-HT receptor subtypes and subsystems, Neuropharmacology, 3 (1990) 457-471.
27. Owens, M.J. and Nemeroff, C.B., Role of serotonin in the pathophysiology of depression: focus on the serotonin transporter, Clin. Chem., 40 (1994) 288-295.
28. 1D receptor in the human brain using a new iodinated radioligand, Mol. Brain Res., 13 (1992) 175-179.
29. Pazos, A., Probst, A., and Palacios, J.M., Serotonin receptors in the human brain. III. Autoradiographic mapping of serotonin-1 receptors, Neuroscience, 21 (1987a) 97-122.
30. Pazos, A., Probst, A., and Palacios, J.M., Serotonin receptors in the human brain. IV. Autoradiographic mapping of serotonin-2 receptors, Neuroscience, 21 (1987b) 123-139.
31. 1A receptor in the rat brain: correlation with receptor binding, J. Neurosci., 12 (1992) 440-453.
32. 2C receptors, Mol. Brain Res., 23 (1994) 163-178.
33. 1Dα serotonin receptor gene expression in trigeminal ganglia: implication for antimigraine drug development, Proc. Natl. Acad. Sci. USA, 91 (1994) 3666-3669.
34. 1C receptor subtypes, Biochem. Biophys. Res. Comm., 181 (1991) 1469-1478.
35. 3H]8-OH-DPAT labels the serotonin transporter in the rat striatum, Eur. J. Pharmacol., 124 (1986) 371-373.
36. Tejani-Butt, S.M., Jang, J., and Pawlyk, A.C., Altered serotonin transporter sites in Alzheimer's disease raphe and hippocampus, NeuroReport, 6 (1995) 1207-1210.
37. Sleight, A.J., Pierce, P.A., Schmidt, A.W., Hekmatpanah, C.R., and Peroutka, S.J., The clinical utility of serotonin receptor active agents in neuropsychiatrie diseases. In: S.J. Peroutka (Ed.), Serotonin Receptor Subtypes: Basic and Clinical Aspects, Wiley-Liss, New York, 1991, pp. 221-227.
38. 1A receptor-related anxiolytics, TIPS, 8 (1987) 432-437.
39. 1 receptor subtypes in the brain of control or 5,7-dihydroxytryptamine-treated rats, J. Neurosci., 6 (1986) 3474-3482.
40. 1D) in the human brain by autoradiography, Neurosci. Lett., 88 (1988) 11-16.
41. Waeber, C. and Palacios, J.M., Serotonin-1 receptor binding sites in the human basal ganglia are decreased in Huntington's chorea but not in Parkinson's disease: a quantitative in vitro autoradiography study, Neuroscience, 32 (1989) 337-347.
42. 1Dβ, Proc. Natl. Acad. Sci. USA, 89 (1992) 3630-3634.
43. 1A binding sites on serotonin containing neurons in the raphe dorsalis and the raphe centralis nuclei of the rat brain, Neurochem. Int., 7 (1985) 1061-1072.
44. 2 receptor subtype mRNAs in rat brain, J. Comp. Neurol., 351 (1995) 357-373.