Validation of a new in vitro dynamic system to simulate infant digestion

Food Chemistry

Volumn 145, Issue , 2014, Pages 1039-1045

  Ménard, Olivia ^a   Cattenoz, Thomas ^b   Guillemin, Hervé ^b   Souchon, Isabelle ^b   Deglaire, Amélie ^a   Dupont, Didier ^a   Picque, Daniel ^b  

^a UMR1253   (France)

^b UMR SayFood   (France)

Author keywords

In vitro digestion; In vivo digestion; Infant formula; Milk proteolysis; Piglet

Indexed keywords

GASTRIC CONDITIONS; GASTROINTESTINAL DIGESTION; GASTROINTESTINAL TRACT; GOOD CORRELATIONS; IN-VITRO DIGESTIONS; IN-VIVO; INFANT FORMULA; PIGLET;

FOOD TECHNOLOGY; PHYSICAL CHEMISTRY;

PROTEOLYSIS;

CASEIN; PANCREATIN; PEPSIN A; TRIACYLGLYCEROL LIPASE;

ANIMAL EXPERIMENT; ARTICLE; ARTIFICIAL MILK; BILE FLOW; COMPUTER PROGRAM; DIGESTION; EXPERIMENTAL PIG; GASTROINTESTINAL TRACT; HYDROLYSIS; INFANT FEEDING; INTESTINE TRANSIT TIME; MATHEMATICAL MODEL; NONHUMAN; PIGLET; PROTEIN DEGRADATION; SIMULATION; STOMACH PH; STOMACH SECRETION; VALIDATION STUDY;

ANIMALIA;

IN VITRO DIGESTION; IN VIVO DIGESTION; INFANT FORMULA; MILK PROTEOLYSIS; PIGLET;

ANIMALS; ANIMALS, NEWBORN; BIOMEDICAL RESEARCH; CASEINS; CROSSES, GENETIC; DIGESTION; FRANCE; GASTROINTESTINAL TRACT; GASTROINTESTINAL TRANSIT; HUMANS; INFANT; INFANT FORMULA; KINETICS; MILK PROTEINS; MODELS, BIOLOGICAL; PEPTIDE FRAGMENTS; PROTEOLYSIS; SOFTWARE; SUS SCROFA;

EID: 84884662147     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2013.09.036     Document Type: Article

References (30)

1. F. Barbé, O. Ménard, Y. Le Gouar, C. Buffière, M.-H. Famelart, B. Laroche, S. Le Feunteun, D. Dupont, and D. Rémond The heat treatment and the gelation are strong determinants of the kinetics of milk proteins digestion and of the peripheral availability of amino acids Food Chemistry 136 2013 1203 1212
2. S. Blanquet, E. Zeijdner, E. Beyssac, J.P. Meunier, S. Denis, R. Havenaar, and M. Alric A dynamic artificial gastrointestinal system for studying the behavior of orally administered drug dosage forms under various physiological conditions Pharmaceutical Research 21 4 2004 585 591 (Pubitemid 38457280)
3. S. Blanquet-Diot, M. Soufi, M. Rambeau, E. Rock, and M. Alric Digestive stability of xanthophylls exceeds that of carotenes as studied in a dynamic in vitro gastrointestinal system Journal of Nutrition 139 5 2009 876 883
4. Y. Boirie, M. Dangin, P. Gachon, M.P. Vasson, J.L. Maubois, and B. Beaufrere Slow and fast dietary proteins differently modulate postprandial protein accretion Proceedings of the National academy of Sciences of the United States of America 94 26 1997 14930 14935 (Pubitemid 28041477)
5. C. Bourlieu, O. Menard, K. Bouzerzour, G. Mandalari, A. Macierzanka, A. Mackie, and D. Dupont Specificity of infant digestive conditions: Some clues for developing relevant in vitro models Critical Reviews in Food Science and Nutrition 2013
6. K. Bouzerzour, F. Morgan, I. Cuinet, C. Bonhomme, J. Jardin, I. Le Huerou-Luron, and D. Dupont In vivo digestion of infant formula in piglets: Protein digestion kinetics and release of bioactive peptides British Journal of Nutrition 108 12 2012 1 10
7. C. Chiang, J. Croom, S. Chuang, P. Chiou, and B. Yu Development of a dynamic system simulating pig gastric digestion Asian-Australasian Journal of Animal Sciences 21 10 2008 1522 1528
8. A. Deglaire, C. Bos, D. Tome, and P.J. Moughan Ileal digestibility of dietary protein in the growing pig and adult human British Journal of Nutrition 102 12 2009 1752 1759
9. A. Deglaire, and P.J. Moughan Animal models for determining amino acid digestibility in humans - A review British Journal of Nutrition 108 2012 S273 S281
10. D. Dupont, R. Boutrou, O. Menard, J. Jardin, G. Tanguy, P. Schuck, B.B. Haab, and J. Leonil Heat treatment of milk during powder manufacture increases casein resistance to simulated infant digestion Food Digestion 1 1-2 2010 28 39
11. D. Dupont, G. Mandalari, D. Molle, J. Jardin, O. Rolet-Repecaud, G. Duboz, J. Leonil, E.N.C. Mills, and A.R. Mackie Food processing increases casein resistance to simulated infant digestion Molecular Nutrition & Food Research 54 11 2010 1677 1689
12. J.D. Elashoff, T.J. Reedy, and J.H. Meyer Analysis of gastric-emptying data Gastroenterology 83 6 1982 1306 1312
13. A. Guerra, L. Etienne-Mesmin, V. Livrelli, S. Denis, S. Blanquet-Diot, and M. Alric Relevance and challenges in modeling human gastric and small intestinal digestion Trends in Biotechnology 30 11 2012 591 600
14. Guillemin, H., Perret, B., Picque, D., Menard, O., & Cattenoz, T. (2010). Logiciel StoRM - Stomach and duodenum Regulation and Monitoring. IDDN.FR.001.230009.000.R.P.2010.000.31235, 290.
15. M.R. Guo, P.F. Fox, A. Flynn, and P.S. Kindstedt Susceptibility of beta-lactoglobulin and sodium caseinate to proteolysis by pepsin and trypsin Journal of Dairy Science 78 11 1995 2336 2344
16. S.J. Hur, B.O. Lim, E.A. Decker, and D.J. McClements In vitro digestion models for food applications Food Chemistry 125 2011 1 12
17. F. Kong, and R.P. Singh Disintegration of solid foods in human stomach Journal of Food Science 73 5 2008 R67 80
18. F.B. Kong, and R.P. Singh A Human Gastric Simulator (HGS) to Study Food Digestion in Human Stomach Journal of Food Science 75 9 2010 E627 E635
19. G. Mandalari, A.M. Mackie, N.M. Rigby, M.S.J. Wickham, and E.N.C. Mills Physiological phosphatidylcholine protects bovine β-lactoglobulin from simulated gastrointestinal proteolysis Molecular Nutrition & Food Research 53 2009 131 139
20. A. Martin, and G. de Jong Enhancing the in vitro Fe2+ bio-accessibility using ascorbate and cold-set whey protein gel particles Dairy Science & Technology 92 2 2012 133 149
21. M. Marzorati, A. Verhelst, G. Luta, R. Sinnott, W. Verstraete, T. Van de Wiele, and S. Possemiers In vitro modulation of the human gastrointestinal microbial community by plant-derived polysaccharide-rich dietary supplements International Journal of Food Microbiology 139 3 2010 168 176
22. M. Minekus, P. Marteau, R. Havenaar, and J.H.J. Huisintveld A multicompartmental dynamic computer-controlled model simulating the stomach and small-intestine Atla-Alternatives to Laboratory Animals 23 2 1995 197 209
23. K. Molly, M.V. Woestyne, and W. Verstraete Development of a 5-Step multichamber reactor as a simulation of the human intestinal microbial ecosystem Applied Microbiology and Biotechnology 39 2 1993 254 258 (Pubitemid 23134616)
24. P.J. Moughan, P.D. Cranwell, and W.C. Smith An evaluation with piglets of bovine-milk, hydrolyzed bovine-milk, and isolated soybean proteins included in infant milk formulas. 2. Stomach-emptying rate and the postprandial change in gastric ph and milk-clotting enzyme-activity Journal of Pediatric Gastroenterology and Nutrition 12 2 1991 253 259
25. P.J. Moughan, G. Schuttert, and M. Leenaars Endogenous amino-acid flow in the stomach and small-intestine of the young growing pig Journal of the Science of Food and Agriculture 60 4 1992 437 442
26. A.M. Rowan, P.J. Moughan, M.N. Wilson, K. Maher, and C. Tasmanjones Comparison of the ileal and fecal digestibility of dietary amino-acids in adult humans and evaluation of the pig as a model animal for digestion studies in man British Journal of Nutrition 71 1 1994 29 42 (Pubitemid 24045310)
27. S. Souliman, S. Blanquet, E. Beyssac, and J.M. Cardot A level A in vitro/in vivo correlation in fasted and fed states using different methods: Applied to solid immediate release oral dosage form European Journal of Pharmaceutical Sciences 27 1 2006 72 79 (Pubitemid 41728257)
28. A. Tharakan, I. Norton, P. Fryer, and S. Bakalis Mass transfer and nutrient absorption in a simulated model of small intestine Journal of Food Science 75 6 2010 E339 E346
29. M. Vardakou, A. Mercuri, T. Naylor, D. Rizzo, J. Butler, P. Connolly, M. Wickham, and R. Faulks Predicting the human in vivo performance of different oral capsule shell types using a novel in vitro dynamic gastric model International Journal of Pharmaceutics 419 1-2 2011 192 199
30. M. Yvon, S. Beucher, P. Scanff, S. Thirouin, and J.P. Pelissier In vitro simulation of gastric digestion of milk proteins - Comparison between in vitro and in vivo data Journal of Agricultural and Food Chemistry 40 2 1992 239 244