A high-content screening assay for small-molecule modulators of oncogene-induced senescence

Journal of Biomolecular Screening

Volumn 18, Issue 9, 2013, Pages 1054-1061

  Bitler, Benjamin G ^a   Fink, Lauren S ^b   Wei, Zhi ^c   Peterson, Jeffrey R ^b   Zhang, Rugang ^a  

^a WISTAR INSTITUTE   (United States)

^b FOX CHASE CANCER CENTER   (United States)

^c University Heights   (United States)

Author keywords

cancer and cancer drugs; cell based assays; high content screening; kinases

Indexed keywords

BETA GALACTOSIDASE; DIMETHYL SULFOXIDE; K RAS PROTEIN; PUROMYCIN;

ARTICLE; CELL PROLIFERATION; CELL TRANSFORMATION; CONTROLLED STUDY; DOWNSTREAM PROCESSING; ENZYME ACTIVITY; FIBROBLAST; HETEROCHROMATIN; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; HUMAN TISSUE; MAMMAL CELL; MOLECULAR LIBRARY; ONCOGENE K RAS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; SENESCENCE; SIGNAL TRANSDUCTION;

CANCER AND CANCER DRUGS; CELL-BASED ASSAYS; HIGH-CONTENT SCREENING; KINASES;

BETA-GALACTOSIDASE; BIOLOGICAL ASSAY; CELL AGING; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; FIBROBLASTS; GENE EXPRESSION REGULATION; GENES, REPORTER; HETEROCHROMATIN; HUMANS; ONCOGENE PROTEIN P21(RAS); PRIMARY CELL CULTURE; PROTEIN KINASE INHIBITORS; SIGNAL TRANSDUCTION; SMALL MOLECULE LIBRARIES;

EID: 84884621590     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057113491827     Document Type: Article

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