Sulfopeptide probes of the CXCR4/CXCL12 interface reveal oligomer-specific contacts and chemokine allostery

ACS Chemical Biology

Volumn 8, Issue 9, 2013, Pages 1955-1963

  Ziarek, Joshua J ^a,d   Getschman, Anthony E ^a   Butler, Stephen J ^b   Taleski, Deni ^b   Stephens, Bryan ^c   Kufareva, Irina ^c   Handel, Tracy M ^c   Payne, Richard J ^b   Volkman, Brian F ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b UNIVERSITY OF SYDNEY   (Australia)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR CXCR4; DIMER; MONOMER; OLIGOMER; STROMAL CELL DERIVED FACTOR 1; SULFOPEPTIDE; TYROSINE; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BINDING AFFINITY; DIMERIZATION; EXTRACELLULAR SPACE; HYDROPHOBICITY; MOLECULAR INTERACTION; MOLECULAR PROBE; MOLECULAR RECOGNITION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; RECEPTOR UPREGULATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SULFATION; TITRIMETRY;

AMINO ACID SEQUENCE; ANIMALS; CHEMOKINE CXCL12; CHO CELLS; CRICETULUS; HUMANS; MODELS, MOLECULAR; PEPTIDES; PROTEIN BINDING; PROTEIN MULTIMERIZATION; RECEPTORS, CXCR4; TYROSINE;

EID: 84884609886     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb400274z     Document Type: Article

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