Sulfotyrosine recognition as marker for druggable sites in the extracellular space

International Journal of Molecular Sciences

Volumn 12, Issue 6, 2011, Pages 3740-3756

  Ziarek, Joshua J ^a   Heroux, Maxime S ^a   Veldkamp, Christopher T ^b   Peterson, Francis C ^a   Volkman, Brian F ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b UNIVERSITY OF WISCONSIN WHITEWATER   (United States)

Author keywords

Alignment; Chemokine; Drug discovery; NMR; Structure; Sulfotyrosine

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR CXCR4; CXCL1 CHEMOKINE; FRACTALKINE; RANTES; STROMAL CELL DERIVED FACTOR 1; SULFOTYROSINE; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG; ALPHA CHEMOKINE; CHEMOKINE RECEPTOR CXCR; LIGAND; TYROSINE; TYROSINE O-SULFATE;

ARTICLE; BINDING SITE; DRUG RESEARCH; EXTRACELLULAR MATRIX; PROTEIN BINDING; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RECEPTOR BINDING; AMINO ACID SEQUENCE; ANALOGS AND DERIVATIVES; CHEMISTRY; EXTRACELLULAR SPACE; HUMAN; METABOLISM; MOLECULAR DYNAMICS; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; BINDING SITES; CHEMOKINES, CXC; EXTRACELLULAR SPACE; HUMANS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CXCR; SEQUENCE ALIGNMENT; TYROSINE;

EID: 79959708032     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms12063740     Document Type: Article

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