Polyclonal hyper-IgE mouse model reveals mechanistic insights into antibody class switch recombination

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 39, 2013, Pages 15770-15775

  Misaghi, Shahram ^a   Senger, Kate ^a   Sai, Tao ^a   Qu, Yan ^a   Sun, Yonglian ^a   Hamidzadeh, Kajal ^a   Nguyen, Allen ^a   Jin, Zhaoyu ^a   Zhou, Meijuan ^a   Yan, Donghong ^a   Lin, Wei Yu ^a   Lin, Zhonghua ^a   Lorenzo, Maria N ^a   Sebrell, Andrew ^a   Ding, Jiabing ^a   Xu, Min ^a   Caplazi, Patrick ^a   Austin, Cary D ^a   Balazs, Mercedesz ^a   Roose Girma, Merone ^a   DeForge, Laura ^a   Warming, Soren ^a   Lee, Wyne P ^a   Dixit, Vishva M ^a   Zarrin, Ali A ^a   more..

^a GENENTECH INC   (United States)

Author keywords

AICDA; Allergy; Asthma; Germline transcription; Immunoglobulin

Indexed keywords

IMMUNOGLOBULIN E ANTIBODY; POLYCLONAL ANTIBODY; REPETITIVE DNA; S REGION PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE LOCUS; GENE REARRANGEMENT; GENETIC ENGINEERING; GENETIC RECOMBINATION; GERM LINE; HYPER IGE SYNDROME; IMMUNOGLOBULIN GENE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

AICDA; ALLERGY; ASTHMA; GERMLINE TRANSCRIPTION; IMMUNOGLOBULIN;

ALLELES; ANIMALS; B-LYMPHOCYTES; GENE KNOCK-IN TECHNIQUES; GENE TARGETING; GENETIC LOCI; GERM CELLS; HYBRIDOMAS; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN E; IMMUNOGLOBULIN EPSILON-CHAINS; IMMUNOGLOBULIN MU-CHAINS; LYMPHOCYTE ACTIVATION; MICE; MODELS, ANIMAL; RECOMBINATION, GENETIC; RNA, MESSENGER;

EID: 84884598894     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1221661110     Document Type: Article

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