-
1
-
-
77953760056
-
Antibody-mediated modulation of immune responses
-
F. Nimmerjahn, and J.V. Ravetch Antibody-mediated modulation of immune responses Immunol. Rev. 236 2010 265 275
-
(2010)
Immunol. Rev.
, vol.236
, pp. 265-275
-
-
Nimmerjahn, F.1
Ravetch, J.V.2
-
2
-
-
0034268780
-
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
-
M. Muramatsu, K. Kinoshita, S. Fagarasan, S. Yamada, Y. Shinkai, and T. Honjo Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme Cell 102 2000 553 563
-
(2000)
Cell
, vol.102
, pp. 553-563
-
-
Muramatsu, M.1
Kinoshita, K.2
Fagarasan, S.3
Yamada, S.4
Shinkai, Y.5
Honjo, T.6
-
3
-
-
34249790004
-
Molecular mechanisms of antibody somatic hypermutation
-
J.M. Di Noia, and M.S. Neuberger Molecular mechanisms of antibody somatic hypermutation Annu. Rev. Biochem. 76 2007 1 22
-
(2007)
Annu. Rev. Biochem.
, vol.76
, pp. 1-22
-
-
Di Noia, J.M.1
Neuberger, M.S.2
-
4
-
-
34249794280
-
Evolution of the immunoglobulin heavy chain class switch recombination mechanism
-
J. Chaudhuri, U. Basu, A. Zarrin, C. Yan, S. Franco, T. Perlot, B. Vuong, J. Wang, R.T. Phan, and A. Datta Evolution of the immunoglobulin heavy chain class switch recombination mechanism Adv. Immunol. 94 2007 157 214
-
(2007)
Adv. Immunol.
, vol.94
, pp. 157-214
-
-
Chaudhuri, J.1
Basu, U.2
Zarrin, A.3
Yan, C.4
Franco, S.5
Perlot, T.6
Vuong, B.7
Wang, J.8
Phan, R.T.9
Datta, A.10
-
5
-
-
77953229115
-
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway
-
M.R. Lieber The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway Annu. Rev. Biochem. 79 2010 181 211
-
(2010)
Annu. Rev. Biochem.
, vol.79
, pp. 181-211
-
-
Lieber, M.R.1
-
6
-
-
78149264026
-
Mapping of switch recombination junctions, a tool for studying DNA repair pathways during immunoglobulin class switching
-
J. Stavnezer, A. Björkman, L. Du, A. Cagigi, and Q. Pan-Hammarström Mapping of switch recombination junctions, a tool for studying DNA repair pathways during immunoglobulin class switching Adv. Immunol. 108 2010 45 109
-
(2010)
Adv. Immunol.
, vol.108
, pp. 45-109
-
-
Stavnezer, J.1
Björkman, A.2
Du, L.3
Cagigi, A.4
Pan-Hammarström, Q.5
-
9
-
-
0036718611
-
Comparative analyses of immunoglobulin genes: Surprises and portents
-
M.F. Flajnik Comparative analyses of immunoglobulin genes: surprises and portents Nat. Rev. Immunol. 2 2002 688 698
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 688-698
-
-
Flajnik, M.F.1
-
11
-
-
29144433461
-
Somatic hypermutation and junctional diversification at Ig heavy chain loci in the nurse shark
-
K. Malecek, J. Brandman, J.E. Brodsky, Y. Ohta, M.F. Flajnik, and E. Hsu Somatic hypermutation and junctional diversification at Ig heavy chain loci in the nurse shark J. Immunol. 175 2005 8105 8115
-
(2005)
J. Immunol.
, vol.175
, pp. 8105-8115
-
-
Malecek, K.1
Brandman, J.2
Brodsky, J.E.3
Ohta, Y.4
Flajnik, M.F.5
Hsu, E.6
-
12
-
-
45849106307
-
The evolution of multiple isotypic IgM heavy chain genes in the shark
-
V. Lee, J.L. Huang, M.F. Lui, K. Malecek, Y. Ohta, A. Mooers, and E. Hsu The evolution of multiple isotypic IgM heavy chain genes in the shark J. Immunol. 180 2008 7461 7470
-
(2008)
J. Immunol.
, vol.180
, pp. 7461-7470
-
-
Lee, V.1
Huang, J.L.2
Lui, M.F.3
Malecek, K.4
Ohta, Y.5
Mooers, A.6
Hsu, E.7
-
13
-
-
80052662001
-
The multiple shark immunoglobulin heavy chain genes rearrange and hypermutate autonomously
-
C. Zhu, W. Feng, J. Weedon, P. Hua, D. Stepanov, Y. Ohta, M.F. Flajnik, and E. Hsu The multiple shark immunoglobulin heavy chain genes rearrange and hypermutate autonomously J. Immunol. 187 2011 2492 2501
-
(2011)
J. Immunol.
, vol.187
, pp. 2492-2501
-
-
Zhu, C.1
Feng, W.2
Weedon, J.3
Hua, P.4
Stepanov, D.5
Ohta, Y.6
Flajnik, M.F.7
Hsu, E.8
-
14
-
-
2542477275
-
Diversity and repertoire of IgW and IgM VH families in the newborn nurse shark
-
L.L. Rumfelt, R.L. Lohr, H. Dooley, and M.F. Flajnik Diversity and repertoire of IgW and IgM VH families in the newborn nurse shark BMC Immunol. 5 2004 8
-
(2004)
BMC Immunol.
, vol.5
, pp. 8
-
-
Rumfelt, L.L.1
Lohr, R.L.2
Dooley, H.3
Flajnik, M.F.4
-
15
-
-
45849107256
-
Immunoglobulin heavy chain exclusion in the shark
-
K. Malecek, V. Lee, W. Feng, J.L. Huang, M.F. Flajnik, Y. Ohta, and E. Hsu Immunoglobulin heavy chain exclusion in the shark PLoS Biol. 6 2008 e157
-
(2008)
PLoS Biol.
, vol.6
, pp. 157
-
-
Malecek, K.1
Lee, V.2
Feng, W.3
Huang, J.L.4
Flajnik, M.F.5
Ohta, Y.6
Hsu, E.7
-
16
-
-
78149476860
-
Error-prone DNA repair activity during somatic hypermutation in shark B lymphocytes
-
C. Zhu, and E. Hsu Error-prone DNA repair activity during somatic hypermutation in shark B lymphocytes J. Immunol. 185 2010 5336 5347
-
(2010)
J. Immunol.
, vol.185
, pp. 5336-5347
-
-
Zhu, C.1
Hsu, E.2
-
17
-
-
0036032290
-
Structural analysis, selection, and ontogeny of the shark new antigen receptor (IgNAR): Identification of a new locus preferentially expressed in early development
-
M. Diaz, R.L. Stanfield, A.S. Greenberg, and M.F. Flajnik Structural analysis, selection, and ontogeny of the shark new antigen receptor (IgNAR): identification of a new locus preferentially expressed in early development Immunogenetics 54 2002 501 512
-
(2002)
Immunogenetics
, vol.54
, pp. 501-512
-
-
Diaz, M.1
Stanfield, R.L.2
Greenberg, A.S.3
Flajnik, M.F.4
-
18
-
-
0036224829
-
Hypermutation in shark immunoglobulin light chain genes results in contiguous substitutions
-
S.S. Lee, D. Tranchina, Y. Ohta, M.F. Flajnik, and E. Hsu Hypermutation in shark immunoglobulin light chain genes results in contiguous substitutions Immunity 16 2002 571 582
-
(2002)
Immunity
, vol.16
, pp. 571-582
-
-
Lee, S.S.1
Tranchina, D.2
Ohta, Y.3
Flajnik, M.F.4
Hsu, E.5
-
19
-
-
0032911308
-
Mutational pattern of the nurse shark antigen receptor gene (NAR) is similar to that of mammalian Ig genes and to spontaneous mutations in evolution: The translesion synthesis model of somatic hypermutation
-
M. Diaz, J. Velez, M. Singh, J. Cerny, and M.F. Flajnik Mutational pattern of the nurse shark antigen receptor gene (NAR) is similar to that of mammalian Ig genes and to spontaneous mutations in evolution: the translesion synthesis model of somatic hypermutation Int. Immunol. 11 1999 825 833
-
(1999)
Int. Immunol.
, vol.11
, pp. 825-833
-
-
Diaz, M.1
Velez, J.2
Singh, M.3
Cerny, J.4
Flajnik, M.F.5
-
20
-
-
0037650190
-
R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells
-
K. Yu, F. Chedin, C.L. Hsieh, T.E. Wilson, and M.R. Lieber R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells Nat. Immunol. 4 2003 442 451
-
(2003)
Nat. Immunol.
, vol.4
, pp. 442-451
-
-
Yu, K.1
Chedin, F.2
Hsieh, C.L.3
Wilson, T.E.4
Lieber, M.R.5
-
21
-
-
0038664358
-
The influence of transcriptional orientation on endogenous switch region function
-
R. Shinkura, M. Tian, M. Smith, K. Chua, Y. Fujiwara, and F.W. Alt The influence of transcriptional orientation on endogenous switch region function Nat. Immunol. 4 2003 435 441
-
(2003)
Nat. Immunol.
, vol.4
, pp. 435-441
-
-
Shinkura, R.1
Tian, M.2
Smith, M.3
Chua, K.4
Fujiwara, Y.5
Alt, F.W.6
-
22
-
-
1842298136
-
Microsites for immunoglobulin switch recombination breakpoints from Xenopus to mammals
-
R. Mussmann, M. Courtet, J. Schwager, and L. Du Pasquier Microsites for immunoglobulin switch recombination breakpoints from Xenopus to mammals Eur. J. Immunol. 27 1997 2610 2619
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 2610-2619
-
-
Mussmann, R.1
Courtet, M.2
Schwager, J.3
Du Pasquier, L.4
-
23
-
-
13444255004
-
An evolutionarily conserved target motif for immunoglobulin class-switch recombination
-
A.A. Zarrin, F.W. Alt, J. Chaudhuri, N. Stokes, D. Kaushal, L. Du Pasquier, and M. Tian An evolutionarily conserved target motif for immunoglobulin class-switch recombination Nat. Immunol. 5 2004 1275 1281
-
(2004)
Nat. Immunol.
, vol.5
, pp. 1275-1281
-
-
Zarrin, A.A.1
Alt, F.W.2
Chaudhuri, J.3
Stokes, N.4
Kaushal, D.5
Du Pasquier, L.6
Tian, M.7
-
24
-
-
14044260062
-
Influence of switch region length on immunoglobulin class switch recombination
-
A.A. Zarrin, M. Tian, J. Wang, T. Borjeson, and F.W. Alt Influence of switch region length on immunoglobulin class switch recombination Proc. Natl. Acad. Sci. USA 102 2005 2466 2470
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 2466-2470
-
-
Zarrin, A.A.1
Tian, M.2
Wang, J.3
Borjeson, T.4
Alt, F.W.5
-
25
-
-
0025630537
-
Boundaries of somatic mutation in rearranged immunoglobulin genes: 5′ boundary is near the promoter, and 3′ boundary is approximately 1 kb from V(D)J gene
-
S.G. Lebecque, and P.J. Gearhart Boundaries of somatic mutation in rearranged immunoglobulin genes: 5′ boundary is near the promoter, and 3′ boundary is approximately 1 kb from V(D)J gene J. Exp. Med. 172 1990 1717 1727
-
(1990)
J. Exp. Med.
, vol.172
, pp. 1717-1727
-
-
Lebecque, S.G.1
Gearhart, P.J.2
-
26
-
-
33748443257
-
The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/- ung-/- mice
-
K. Xue, C. Rada, and M.S. Neuberger The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/- ung-/- mice J. Exp. Med. 203 2006 2085 2094
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2085-2094
-
-
Xue, K.1
Rada, C.2
Neuberger, M.S.3
-
27
-
-
0037866984
-
H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation
-
B. Reina-San-Martin, S. Difilippantonio, L. Hanitsch, R.F. Masilamani, A. Nussenzweig, and M.C. Nussenzweig H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation J. Exp. Med. 197 2003 1767 1778
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1767-1778
-
-
Reina-San-Martin, B.1
Difilippantonio, S.2
Hanitsch, L.3
Masilamani, R.F.4
Nussenzweig, A.5
Nussenzweig, M.C.6
-
28
-
-
0032578528
-
Trans-chromosomal recombination within the Ig heavy chain switch region in B lymphocytes
-
M. Kingzette, H. Spieker-Polet, P.C. Yam, S.K. Zhai, and K.L. Knight Trans-chromosomal recombination within the Ig heavy chain switch region in B lymphocytes Proc. Natl. Acad. Sci. USA 95 1998 11840 11845
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 11840-11845
-
-
Kingzette, M.1
Spieker-Polet, H.2
Yam, P.C.3
Zhai, S.K.4
Knight, K.L.5
-
29
-
-
18644380562
-
Interallelic class switch recombination contributes significantly to class switching in mouse B cells
-
S. Reynaud, L. Delpy, L. Fleury, H.-L. Dougier, C. Sirac, and M. Cogné Interallelic class switch recombination contributes significantly to class switching in mouse B cells J. Immunol. 174 2005 6176 6183
-
(2005)
J. Immunol.
, vol.174
, pp. 6176-6183
-
-
Reynaud, S.1
Delpy, L.2
Fleury, L.3
Dougier, H.-L.4
Sirac, C.5
Cogné, M.6
-
30
-
-
0027960735
-
Complete genomic sequence and patterns of transcription of a member of an unusual family of closely related, chromosomally dispersed Ig gene clusters in Raja
-
M. Anderson, C. Amemiya, C. Luer, R. Litman, J. Rast, Y. Niimura, and G. Litman Complete genomic sequence and patterns of transcription of a member of an unusual family of closely related, chromosomally dispersed Ig gene clusters in Raja Int. Immunol. 6 1994 1661 1670
-
(1994)
Int. Immunol.
, vol.6
, pp. 1661-1670
-
-
Anderson, M.1
Amemiya, C.2
Luer, C.3
Litman, R.4
Rast, J.5
Niimura, Y.6
Litman, G.7
-
31
-
-
39149099085
-
Two levels of protection for the B cell genome during somatic hypermutation
-
M. Liu, J.L. Duke, D.J. Richter, C.G. Vinuesa, C.C. Goodnow, S.H. Kleinstein, and D.G. Schatz Two levels of protection for the B cell genome during somatic hypermutation Nature 451 2008 841 845
-
(2008)
Nature
, vol.451
, pp. 841-845
-
-
Liu, M.1
Duke, J.L.2
Richter, D.J.3
Vinuesa, C.G.4
Goodnow, C.C.5
Kleinstein, S.H.6
Schatz, D.G.7
-
32
-
-
78650308767
-
Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes
-
A. Yamane, W. Resch, N. Kuo, S. Kuchen, Z. Li, H.W. Sun, D.F. Robbiani, K. McBride, M.C. Nussenzweig, and R. Casellas Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes Nat. Immunol. 12 2011 62 69
-
(2011)
Nat. Immunol.
, vol.12
, pp. 62-69
-
-
Yamane, A.1
Resch, W.2
Kuo, N.3
Kuchen, S.4
Li, Z.5
Sun, H.W.6
Robbiani, D.F.7
McBride, K.8
Nussenzweig, M.C.9
Casellas, R.10
-
33
-
-
80053558376
-
Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells
-
R. Chiarle, Y. Zhang, R.L. Frock, S.M. Lewis, B. Molinie, Y.J. Ho, D.R. Myers, V.W. Choi, M. Compagno, and D.J. Malkin Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells Cell 147 2011 107 119
-
(2011)
Cell
, vol.147
, pp. 107-119
-
-
Chiarle, R.1
Zhang, Y.2
Frock, R.L.3
Lewis, S.M.4
Molinie, B.5
Ho, Y.J.6
Myers, D.R.7
Choi, V.W.8
Compagno, M.9
Malkin, D.J.10
-
34
-
-
80053502216
-
Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes
-
I.A. Klein, W. Resch, M. Jankovic, T. Oliveira, A. Yamane, H. Nakahashi, M. Di Virgilio, A. Bothmer, A. Nussenzweig, and D.F. Robbiani Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes Cell 147 2011 95 106
-
(2011)
Cell
, vol.147
, pp. 95-106
-
-
Klein, I.A.1
Resch, W.2
Jankovic, M.3
Oliveira, T.4
Yamane, A.5
Nakahashi, H.6
Di Virgilio, M.7
Bothmer, A.8
Nussenzweig, A.9
Robbiani, D.F.10
-
35
-
-
73349098453
-
Switch recombination and somatic hypermutation are controlled by the heavy chain 3′ enhancer region
-
W.A. Dunnick, J.T. Collins, J. Shi, G. Westfield, C. Fontaine, P. Hakimpour, and F.N. Papavasiliou Switch recombination and somatic hypermutation are controlled by the heavy chain 3′ enhancer region J. Exp. Med. 206 2009 2613 2623
-
(2009)
J. Exp. Med.
, vol.206
, pp. 2613-2623
-
-
Dunnick, W.A.1
Collins, J.T.2
Shi, J.3
Westfield, G.4
Fontaine, C.5
Hakimpour, P.6
Papavasiliou, F.N.7
-
37
-
-
65249129851
-
H3 trimethyl K9 and H3 acetyl K9 chromatin modifications are associated with class switch recombination
-
F.L. Kuang, Z. Luo, and M.D. Scharff H3 trimethyl K9 and H3 acetyl K9 chromatin modifications are associated with class switch recombination Proc. Natl. Acad. Sci. USA 106 2009 5288 5293
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 5288-5293
-
-
Kuang, F.L.1
Luo, Z.2
Scharff, M.D.3
-
38
-
-
68149158825
-
S region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombination
-
L. Wang, R. Wuerffel, S. Feldman, A.A. Khamlichi, and A.L. Kenter S region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombination J. Exp. Med. 206 2009 1817 1830
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1817-1830
-
-
Wang, L.1
Wuerffel, R.2
Feldman, S.3
Khamlichi, A.A.4
Kenter, A.L.5
-
39
-
-
77955866537
-
PTIP promotes chromatin changes critical for immunoglobulin class switch recombination
-
J.A. Daniel, M.A. Santos, Z. Wang, C. Zang, K.R. Schwab, M. Jankovic, D. Filsuf, H.T. Chen, A. Gazumyan, and A. Yamane PTIP promotes chromatin changes critical for immunoglobulin class switch recombination Science 329 2010 917 923
-
(2010)
Science
, vol.329
, pp. 917-923
-
-
Daniel, J.A.1
Santos, M.A.2
Wang, Z.3
Zang, C.4
Schwab, K.R.5
Jankovic, M.6
Filsuf, D.7
Chen, H.T.8
Gazumyan, A.9
Yamane, A.10
-
41
-
-
25144496639
-
AID from bony fish catalyzes class switch recombination
-
V.M. Barreto, Q. Pan-Hammarstrom, Y. Zhao, L. Hammarstrom, Z. Misulovin, and M.C. Nussenzweig AID from bony fish catalyzes class switch recombination J. Exp. Med. 202 2005 733 738
-
(2005)
J. Exp. Med.
, vol.202
, pp. 733-738
-
-
Barreto, V.M.1
Pan-Hammarstrom, Q.2
Zhao, Y.3
Hammarstrom, L.4
Misulovin, Z.5
Nussenzweig, M.C.6
-
42
-
-
30344463017
-
Evolution of class switch recombination function in fish activation-induced cytidine deaminase, AID
-
K. Wakae, B.G. Magor, H. Saunders, H. Nagaoka, A. Kawamura, K. Kinoshita, T. Honjo, and M. Muramatsu Evolution of class switch recombination function in fish activation-induced cytidine deaminase, AID Int. Immunol. 18 2006 41 47
-
(2006)
Int. Immunol.
, vol.18
, pp. 41-47
-
-
Wakae, K.1
Magor, B.G.2
Saunders, H.3
Nagaoka, H.4
Kawamura, A.5
Kinoshita, K.6
Honjo, T.7
Muramatsu, M.8
|